-
1
-
-
23144439258
-
Intracellular interactions between nucleos(t)ide inhibitors of HIV reverse transcriptase
-
Ray AS. Intracellular interactions between nucleos(t)ide inhibitors of HIV reverse transcriptase. AIDS Rev 2005; 7:113-125.
-
(2005)
AIDS Rev
, vol.7
, pp. 113-125
-
-
Ray, A.S.1
-
2
-
-
0023266214
-
The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial
-
Richman DD, Fischl MA, Grieco MH, et al. The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial. N Engl J Med 1987; 317:192-197.
-
(1987)
N Engl J Med
, vol.317
, pp. 192-197
-
-
Richman, D.D.1
Fischl, M.A.2
Grieco, M.H.3
-
3
-
-
30944468562
-
Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz; for HIV
-
Gallant JE, DeJesus E, Arrihas JR, et al. Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz; for HIV. N Engl J Med 2006; 354:251-260.
-
(2006)
N Engl J Med
, vol.354
, pp. 251-260
-
-
Gallant, J.E.1
DeJesus, E.2
Arrihas, J.R.3
-
4
-
-
4744372267
-
Phosphorylation of thymidine and AZT in heart mitochondria: Elucidation of a novel mechanism of AZT cardiotoxicity
-
McKee EE, Bentley AT, Hatch M, Gingerich J, Susan-Resiga D. Phosphorylation of thymidine and AZT in heart mitochondria: elucidation of a novel mechanism of AZT cardiotoxicity. Cardiovasc Toxicol 2004; 4:155-167.
-
(2004)
Cardiovasc Toxicol
, vol.4
, pp. 155-167
-
-
McKee, E.E.1
Bentley, A.T.2
Hatch, M.3
Gingerich, J.4
Susan-Resiga, D.5
-
5
-
-
33744915313
-
3′-Azido-3′-deoxythymidine (AZT) is a competitive inhibitor of thymidine phosphorylation in isolated rat heart and liver mitochondria
-
Lynx MD, McKee EE. 3′-Azido-3′-deoxythymidine (AZT) is a competitive inhibitor of thymidine phosphorylation in isolated rat heart and liver mitochondria. Biochem Pharmacol 2006; 72:239-243.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 239-243
-
-
Lynx, M.D.1
McKee, E.E.2
-
6
-
-
33645124958
-
3′-Azido-3′-deoxythymidine, (AZT) inhibits thymidine phosphorylation in isolated rat liver mitochondria: A possible mechanism of AZT hepatotoxicity
-
Lynx MD, Bentley AT, McKee EE. 3′-Azido-3′-deoxythymidine, (AZT) inhibits thymidine phosphorylation in isolated rat liver mitochondria: a possible mechanism of AZT hepatotoxicity. Biochem Pharmacol 2006; 71:1342-1348.
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 1342-1348
-
-
Lynx, M.D.1
Bentley, A.T.2
McKee, E.E.3
-
7
-
-
0024353932
-
Cellular pharmacology of 3′-azido-3′-deoxythymidine with evidence of incorporation into DNA of human bone marrow cells
-
Sommadossi JP, Carlisle R, Zhou Z. Cellular pharmacology of 3′-azido-3′-deoxythymidine with evidence of incorporation into DNA of human bone marrow cells. Mol Pharmacol 1989; 36:9-14.
-
(1989)
Mol Pharmacol
, vol.36
, pp. 9-14
-
-
Sommadossi, J.P.1
Carlisle, R.2
Zhou, Z.3
-
8
-
-
0025143813
-
Incorporation of 3′-azido-3′-deoxythymidine into cellular DNA and its removal in a human leukemic cell line
-
Vazquez-Padua MA, Starnes MC, Cheng YC. Incorporation of 3′-azido-3′-deoxythymidine into cellular DNA and its removal in a human leukemic cell line. Cancer Commun 1990; 2:55-62.
-
(1990)
Cancer Commun
, vol.2
, pp. 55-62
-
-
Vazquez-Padua, M.A.1
Starnes, M.C.2
Cheng, Y.C.3
-
9
-
-
0027157404
-
Inhibition of mammalian DNA polymerase-associated 3′ to 5′ exonuclease activity by 5′-monophosphates of 3′-azido-3′-deoxythymidine and 3′-amino-3′-deoxythymidine
-
Bridges EG, Faraj A, Sommadossi JP. Inhibition of mammalian DNA polymerase-associated 3′ to 5′ exonuclease activity by 5′-monophosphates of 3′-azido-3′-deoxythymidine and 3′-amino-3′-deoxythymidine. Biochem Pharmacol 1993; 45:1571-1576.
-
(1993)
Biochem Pharmacol
, vol.45
, pp. 1571-1576
-
-
Bridges, E.G.1
Faraj, A.2
Sommadossi, J.P.3
-
10
-
-
0027451533
-
Reduction of 3′-azido-2′,3′-dideoxymideosides to their 3′-amino metabolite is mediated by cytochrome P-450 and NADPH-cytochrome P-450 reductase in rat liver microsomes
-
Cretton EM, Sommadossi JR Reduction of 3′-azido-2′,3′-dideoxymideosides to their 3′-amino metabolite is mediated by cytochrome P-450 and NADPH-cytochrome P-450 reductase in rat liver microsomes. Drug Metab Dispos 1993; 21:946-950.
-
(1993)
Drug Metab Dispos
, vol.21
, pp. 946-950
-
-
Cretton, E.M.1
Sommadossi, J.R.2
-
11
-
-
0035891563
-
Zidovudine phosphorylation and mitochondrial toxicity in vitro
-
Sales SD, Hoggard PG, Sunderland D, Khoo S, Hart CA, Back DJ. Zidovudine phosphorylation and mitochondrial toxicity in vitro. Toxicol Appl Pharmacol 2001; 177:54-58.
-
(2001)
Toxicol Appl Pharmacol
, vol.177
, pp. 54-58
-
-
Sales, S.D.1
Hoggard, P.G.2
Sunderland, D.3
Khoo, S.4
Hart, C.A.5
Back, D.J.6
-
12
-
-
0022996630
-
Phosphorylation of 3′-azido-3′-deoxythymidine and selective interaction of the Y-triphosphate with human immunodeficiency virus reverse transcriptase
-
Furman PA, Fyfe JA, St Clair MH, et al. Phosphorylation of 3′-azido-3′-deoxythymidine and selective interaction of the Y-triphosphate with human immunodeficiency virus reverse transcriptase. Proc Natl Acad Sci U S A 1986; 83:8333-8337.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 8333-8337
-
-
Furman, P.A.1
Fyfe, J.A.2
St Clair, M.H.3
-
13
-
-
0034452004
-
Purine nucleoside phosphorylases: Properties, functions, and clinical aspects
-
Bzowska A, Kulikowska E, Shugar D. Purine nucleoside phosphorylases: properties, functions, and clinical aspects. Pharmacol Ther 2000; 88:349-425.
-
(2000)
Pharmacol Ther
, vol.88
, pp. 349-425
-
-
Bzowska, A.1
Kulikowska, E.2
Shugar, D.3
-
14
-
-
1642461500
-
Role of purine nucleoside p hosphorylase in interactions between 2′,3′-dideoxyinosine and allogerinol, ganciclovir, or tenofovir
-
Ray AS, Olson L, Fridland A. Role of purine nucleoside p hosphorylase in interactions between 2′,3′-dideoxyinosine and allogerinol, ganciclovir, or tenofovir. Antimicrob Agents ther 2004; 48:1089-1095.
-
(2004)
Antimicrob Agents ther
, vol.48
, pp. 1089-1095
-
-
Ray, A.S.1
Olson, L.2
Fridland, A.3
-
15
-
-
11244277325
-
CD4 cell decline with didanosine and tenofovir and failure of triple nucleoside/nucleotide regimens may be related
-
Kakuda TN, Anderson PL, Becker SL. CD4 cell decline with didanosine and tenofovir and failure of triple nucleoside/nucleotide regimens may be related. AIDS 2004; 18:2442-2444.
-
(2004)
AIDS
, vol.18
, pp. 2442-2444
-
-
Kakuda, T.N.1
Anderson, P.L.2
Becker, S.L.3
-
16
-
-
0038730672
-
Mechanism of inhibition of T-acute lymphoblastic leukemia cells by PNP inhibitor-BCX-1777
-
Bantia S, Ananth SL, Parker CD, Horn LL, Upshaw R. Mechanism of inhibition of T-acute lymphoblastic leukemia cells by PNP inhibitor-BCX-1777. Int Immunopharmacol 2003; 3:879-887.
-
(2003)
Int Immunopharmacol
, vol.3
, pp. 879-887
-
-
Bantia, S.1
Ananth, S.L.2
Parker, C.D.3
Horn, L.L.4
Upshaw, R.5
-
17
-
-
12144286268
-
Unexpected CD4 cell count decline in patients receiving didanosine and tenofovir-based regimens despite undetectable viral load
-
Negredo E, Molto J, Burger D, et al. Unexpected CD4 cell count decline in patients receiving didanosine and tenofovir-based regimens despite undetectable viral load. AIDS 2004; 18:459-463.
-
(2004)
AIDS
, vol.18
, pp. 459-463
-
-
Negredo, E.1
Molto, J.2
Burger, D.3
-
18
-
-
20244390456
-
+ T-cell decline in HIV-infected patients with complete virus suppression taking tenofovir and didanosine
-
+ T-cell decline in HIV-infected patients with complete virus suppression taking tenofovir and didanosine. AIDS 2005; 19:569-575.
-
(2005)
AIDS
, vol.19
, pp. 569-575
-
-
Barrios, A.1
Rendon, A.2
Negredo, E.3
-
19
-
-
0038369913
-
A randomized trial to study first-line combination therapy with or without a protease inhibitor in HIV-1-infected patients
-
van Leeuwen R, Katlama C, Murphy RL, et al. A randomized trial to study first-line combination therapy with or without a protease inhibitor in HIV-1-infected patients. AIDS 2003; 17:987-999.
-
(2003)
AIDS
, vol.17
, pp. 987-999
-
-
van Leeuwen, R.1
Katlama, C.2
Murphy, R.L.3
-
20
-
-
0142125266
-
Low efficacy and high frequency of adverse events in a randomized trial of the triple nucleoside regimen abacavir, stavudine and didanosine
-
Gerstoft J, Kirk O, Obel N, et al. Low efficacy and high frequency of adverse events in a randomized trial of the triple nucleoside regimen abacavir, stavudine and didanosine. AIDS 2003; 17:2045-2052.
-
(2003)
AIDS
, vol.17
, pp. 2045-2052
-
-
Gerstoft, J.1
Kirk, O.2
Obel, N.3
-
21
-
-
2342537759
-
Triple-nucleoside regimens versus efavirenz-containing repimens for the initial treatment of HIV-1 infection
-
Gulick RM, Ribaudo HJ, Shikuma CM, et al. Triple-nucleoside regimens versus efavirenz-containing repimens for the initial treatment of HIV-1 infection. N Eng J Med 2004; 350:1850-1861.
-
(2004)
N Eng J Med
, vol.350
, pp. 1850-1861
-
-
Gulick, R.M.1
Ribaudo, H.J.2
Shikuma, C.M.3
-
22
-
-
2142657848
-
Which nucleoside and nucleotide backbone combinations select for the K65R mutation in HIV-1 reverse transcriptase
-
Winston A, Pozniak A, Mandalia S, Gazzard B, Pillay D, Nelson M. Which nucleoside and nucleotide backbone combinations select for the K65R mutation in HIV-1 reverse transcriptase. AIDS 2004; 18:949-951.
-
(2004)
AIDS
, vol.18
, pp. 949-951
-
-
Winston, A.1
Pozniak, A.2
Mandalia, S.3
Gazzard, B.4
Pillay, D.5
Nelson, M.6
-
23
-
-
3142682708
-
Poor virologic responses and early emergence of resistance in treatment naive, HIV-infected patients receiving a once daily triple nucleoside regimen of didanosine, lamivudine, and tenofovir DF
-
8-11 February, San Francisco, CA, USA. Abstract 51
-
Jemsek Hutcherson P, Harper E. Poor virologic responses and early emergence of resistance in treatment naive, HIV-infected patients receiving a once daily triple nucleoside regimen of didanosine, lamivudine, and tenofovir DF. 11th Conference on Retroviruses and Opportunistic Infections. 8-11 February 2004, San Francisco, CA, USA. Abstract 51.
-
(2004)
11th Conference on Retroviruses and Opportunistic Infections
-
-
Jemsek Hutcherson, P.1
Harper, E.2
-
24
-
-
27944472569
-
Early virologic nonresponse to tenofovir, abacavir, and lamivudine in HIV-infected antiretroviral-naive subjects
-
Gallant JE, Rodriguez AE, Weinberg WG, et al. Early virologic nonresponse to tenofovir, abacavir, and lamivudine in HIV-infected antiretroviral-naive subjects. J Infect Dis 2005; 192:1921-1930.
-
(2005)
J Infect Dis
, vol.192
, pp. 1921-1930
-
-
Gallant, J.E.1
Rodriguez, A.E.2
Weinberg, W.G.3
-
25
-
-
53149102969
-
-
Panel on Antiretroviral Guidelines for Adults and Adolescents. dolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services. (Updated 29 January 2008. Accessed 24 April 2008.) Available from http://aidsinfo.nih.gov/ContentFiles/AdultandAdeloscentGL.pdf
-
Panel on Antiretroviral Guidelines for Adults and Adolescents. dolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services. (Updated 29 January 2008. Accessed 24 April 2008.) Available from http://aidsinfo.nih.gov/ContentFiles/AdultandAdeloscentGL.pdf
-
-
-
-
26
-
-
0037144629
-
An efficient and large-scale enantioselective synthesis of PNP405: A purine nucleoside phosphorylase inhibitor
-
Prashad M, Hat D, Chen L, Kim HY, Repic O, Blacklock TJ. An efficient and large-scale enantioselective synthesis of PNP405: a purine nucleoside phosphorylase inhibitor. J Org Chem 2002; 67:6612-6617.
-
(2002)
J Org Chem
, vol.67
, pp. 6612-6617
-
-
Prashad, M.1
Hat, D.2
Chen, L.3
Kim, H.Y.4
Repic, O.5
Blacklock, T.J.6
-
27
-
-
33947430923
-
Simultaneous quantitation of the nucleotide analog adefovir, its phosphorylated anabolites and 2′-deoxyadenosine triphosyhate by ion-pairing LC/MS/MS
-
Vela E, Olson LY, Huang A, Fridland A, Ray AS. Simultaneous quantitation of the nucleotide analog adefovir, its phosphorylated anabolites and 2′-deoxyadenosine triphosyhate by ion-pairing LC/MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci 2007; 848:335-343.
-
(2007)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.848
, pp. 335-343
-
-
Vela, E.1
Olson, L.Y.2
Huang, A.3
Fridland, A.4
Ray, A.S.5
-
28
-
-
0028143584
-
Physiological concentrations of purines and pyrimidines
-
Traut TW. Physiological concentrations of purines and pyrimidines. Mol Cell Biochem 1994; 140:1-22.
-
(1994)
Mol Cell Biochem
, vol.140
, pp. 1-22
-
-
Traut, T.W.1
-
29
-
-
0001707601
-
3′-Azido-3′-deoxythymidine (BW A509U): An antiviral agent that inhibits the infectivity and cyropathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro
-
Mitsuya H, Weinhold KJ, Furman PA, et al. 3′-Azido-3′-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cyropathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro. Proc Natl Acad Sci U S A 1985; 82:7096-7100.
-
(1985)
Proc Natl Acad Sci U S A
, vol.82
, pp. 7096-7100
-
-
Mitsuya, H.1
Weinhold, K.J.2
Furman, P.A.3
-
30
-
-
0025337365
-
Relationship of deoxynucleotide changes to inhibition of DNA synthesis induced by the antiretroviral agent 3′-azido-3′-deoxythymidine and release of its monophosphate by human lymphoid cells (CCRF-CEM)
-
Fridland A, Connelly MC, Ashmun R. Relationship of deoxynucleotide changes to inhibition of DNA synthesis induced by the antiretroviral agent 3′-azido-3′-deoxythymidine and release of its monophosphate by human lymphoid cells (CCRF-CEM). Mol Pharmacol 1990; 37:665-670.
-
(1990)
Mol Pharmacol
, vol.37
, pp. 665-670
-
-
Fridland, A.1
Connelly, M.C.2
Ashmun, R.3
-
31
-
-
0021789719
-
Relations between synthesis of deoxyribonucleotides and DNA replication in 3T6 fibroblasts
-
Nicander B, Reichard P. Relations between synthesis of deoxyribonucleotides and DNA replication in 3T6 fibroblasts. J Biol Chem 1985; 260:5376-5381.
-
(1985)
J Biol Chem
, vol.260
, pp. 5376-5381
-
-
Nicander, B.1
Reichard, P.2
-
32
-
-
0032702725
-
9-(2-phosphonylmethoxyethyl) derivatives of purine nucleotide analogs: A comparison of their metabolism and interaction with cellular DNA synthesis
-
Kramata P, Downey KM. 9-(2-phosphonylmethoxyethyl) derivatives of purine nucleotide analogs: A comparison of their metabolism and interaction with cellular DNA synthesis. Mol Pharmacol 1999; 56:1262-1270.
-
(1999)
Mol Pharmacol
, vol.56
, pp. 1262-1270
-
-
Kramata, P.1
Downey, K.M.2
-
33
-
-
0025339708
-
Selective action of 3′-azido-3′-deoxythymidine 5′-triphosphate on viral reverse transcriptases and human DNA polymerases
-
Huang P, Farquhar D, Plunkett W. Selective action of 3′-azido-3′-deoxythymidine 5′-triphosphate on viral reverse transcriptases and human DNA polymerases. J Biol Chem 1990; 265:11914-11918.
-
(1990)
J Biol Chem
, vol.265
, pp. 11914-11918
-
-
Huang, P.1
Farquhar, D.2
Plunkett, W.3
-
34
-
-
0026786397
-
Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA
-
Copeland WC, Chen MS, Wang TS. Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA. J Biol Chem 1992; 267:21459-21464.
-
(1992)
J Biol Chem
, vol.267
, pp. 21459-21464
-
-
Copeland, W.C.1
Chen, M.S.2
Wang, T.S.3
-
35
-
-
0026604666
-
Interactions of azidothymidine triphosphate with the cellular DNA polymerases alpha, delta, and epsilon and with DNA primase
-
Nickel W, Austermann S, Bialek G, Grosse E, Interactions of azidothymidine triphosphate with the cellular DNA polymerases alpha, delta, and epsilon and with DNA primase. J Biol Chem 1992; 267:848-854.
-
(1992)
J Biol Chem
, vol.267
, pp. 848-854
-
-
Nickel, W.1
Austermann, S.2
Bialek, G.3
Grosse, E.4
-
36
-
-
0035798566
-
Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase
-
Johnson AA, Ray AS, Hanes J, et al. Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase. J Biol Chem 2001; 276:40847-40857.
-
(2001)
J Biol Chem
, vol.276
, pp. 40847-40857
-
-
Johnson, A.A.1
Ray, A.S.2
Hanes, J.3
-
37
-
-
0037220313
-
Assessment of the effect of phosphorylated metabolites of anti-human immunodeficiency virus and anti-hepatitis B virus pyrimidine analogs on the behavior of human deoxycytidylate deaminase
-
Liou JY, Krishnan P, Hsieh CC, Dutschman GE, Cheng YC. Assessment of the effect of phosphorylated metabolites of anti-human immunodeficiency virus and anti-hepatitis B virus pyrimidine analogs on the behavior of human deoxycytidylate deaminase. Mol Pharmacol 2003; 63:105-110.
-
(2003)
Mol Pharmacol
, vol.63
, pp. 105-110
-
-
Liou, J.Y.1
Krishnan, P.2
Hsieh, C.C.3
Dutschman, G.E.4
Cheng, Y.C.5
-
38
-
-
0042357238
-
Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase
-
Lewandowicz A, Tyler PC, Evans GB, Furneaux RH, Schramm VL. Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase. J Biol Chem 2003; 278:31465-31468.
-
(2003)
J Biol Chem
, vol.278
, pp. 31465-31468
-
-
Lewandowicz, A.1
Tyler, P.C.2
Evans, G.B.3
Furneaux, R.H.4
Schramm, V.L.5
-
40
-
-
0031916651
-
Anti-human immunodeficiency virus activity and cellular metabolism of a potential prodrug of the acyclic nucleoside phosphonate 9-R-(2-phosphonomethoxypropyl) adenine (PMPA), bis(isopropyloxymethylcarbonyl)PMPA
-
Robbins BL, Srinivas RV, Kim C, Bischofberger N, Fridland A. Anti-human immunodeficiency virus activity and cellular metabolism of a potential prodrug of the acyclic nucleoside phosphonate 9-R-(2-phosphonomethoxypropyl) adenine (PMPA), bis(isopropyloxymethylcarbonyl)PMPA. Antimicrob Agents Chemother 1998; 42:612-617.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 612-617
-
-
Robbins, B.L.1
Srinivas, R.V.2
Kim, C.3
Bischofberger, N.4
Fridland, A.5
-
41
-
-
0034806946
-
Phase I/ II trial of the pharmacokinetics, safety, and antiretroviral activity of tenofovir disoproxil fumarate in human immunodeficiency virus-infected adults
-
Barditch-Crovo P, Deeks SG, Collier A, et al. Phase I/ II trial of the pharmacokinetics, safety, and antiretroviral activity of tenofovir disoproxil fumarate in human immunodeficiency virus-infected adults. Antimicrob Agents Chemother 2001; 45:2733-2739.
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 2733-2739
-
-
Barditch-Crovo, P.1
Deeks, S.G.2
Collier, A.3
-
42
-
-
0038012639
-
Metabolism of tenofovir and didanosine in quiescent or stimulated human peripheral blood mononuclear cells
-
Robbins BL, Wilcox CK, Fridland A, Rodman JH. Metabolism of tenofovir and didanosine in quiescent or stimulated human peripheral blood mononuclear cells. Pharmacotherapy 2003; 23:695-701.
-
(2003)
Pharmacotherapy
, vol.23
, pp. 695-701
-
-
Robbins, B.L.1
Wilcox, C.K.2
Fridland, A.3
Rodman, J.H.4
-
43
-
-
20944435946
-
Measurement of intracellular didanosine and tenofovir phosphorylated metabolites and possible interaction of the two drugs in human immunodeficiency virus-infected patients
-
Pruvost A, Negredo E, Benech H, et al. Measurement of intracellular didanosine and tenofovir phosphorylated metabolites and possible interaction of the two drugs in human immunodeficiency virus-infected patients. Antimicrob Agents Chemother 2005; 49:1907-1914.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 1907-1914
-
-
Pruvost, A.1
Negredo, E.2
Benech, H.3
-
44
-
-
20444483684
-
Lack of a metabolic and antiviral drug interaction between tenofovir, abacavir and lamivudine
-
Ray AS, Myrick F, Vela JE, et al. Lack of a metabolic and antiviral drug interaction between tenofovir, abacavir and lamivudine. Antivir Ther 2005; 10:451-457.
-
(2005)
Antivir Ther
, vol.10
, pp. 451-457
-
-
Ray, A.S.1
Myrick, F.2
Vela, J.E.3
-
45
-
-
22344455482
-
Intracellular pharmacokinetics of tenofovir diphosphate, carbovir triphosphate, and lamivudine triphosphate in patients receiving triple-nucleoside regimens
-
Hawkins T, Veikley W, St Claire RL, III, Guyer B, Clark N, Kearney BP. Intracellular pharmacokinetics of tenofovir diphosphate, carbovir triphosphate, and lamivudine triphosphate in patients receiving triple-nucleoside regimens. J Acquir Immune Defic Syndr 2005; 39:406-411.
-
(2005)
J Acquir Immune Defic Syndr
, vol.39
, pp. 406-411
-
-
Hawkins, T.1
Veikley, W.2
St Claire III, R.L.3
Guyer, B.4
Clark, N.5
Kearney, B.P.6
-
46
-
-
0035819909
-
Abacavirlamivudine-zidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial
-
Staszewski S, Keiser P, Montaner J, et al. Abacavirlamivudine-zidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial. JAMA 2001; 285:1155-1163.
-
(2001)
JAMA
, vol.285
, pp. 1155-1163
-
-
Staszewski, S.1
Keiser, P.2
Montaner, J.3
-
47
-
-
0038369024
-
K65R with and without S68: A new resistance profile in vivo detected in most patients failing abacavir, didanosine and stavudine
-
Roge BT, Katzenstein TL, Obel N, et al. K65R with and without S68: a new resistance profile in vivo detected in most patients failing abacavir, didanosine and stavudine. Antivir, Ther 2003; 8:173-182.
-
(2003)
Antivir, Ther
, vol.8
, pp. 173-182
-
-
Roge, B.T.1
Katzenstein, T.L.2
Obel, N.3
-
48
-
-
33745450105
-
Virological response to a triple nucleoside/nucleotide analogue regimen over 48 weeks in HIV-1-infected adults in Africa
-
DART Virology Group and Trial Team
-
DART Virology Group and Trial Team. Virological response to a triple nucleoside/nucleotide analogue regimen over 48 weeks in HIV-1-infected adults in Africa. AIDS 2006; 20:1391-1399.
-
(2006)
AIDS
, vol.20
, pp. 1391-1399
-
-
-
49
-
-
33644511106
-
An open-label, randomized comparative pilot study of a single-class quadruple therapy regimen versus a 2-class triple therapy regimen for individuals initiating antiretroviral therapy
-
Moyle G, Higgs C, Teague A, et al. An open-label, randomized comparative pilot study of a single-class quadruple therapy regimen versus a 2-class triple therapy regimen for individuals initiating antiretroviral therapy. Antivir Ther 2006; 11:73-78.
-
(2006)
Antivir Ther
, vol.11
, pp. 73-78
-
-
Moyle, G.1
Higgs, C.2
Teague, A.3
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