메뉴 건너뛰기




Volumn 317, Issue 1-2, 2008, Pages 189-196

Activation of peroxisome proliferator-activated receptor gamma inhibits endothelin-1-induced cardiac hypertrophy via the calcineurin/NFAT signaling pathway

Author keywords

Calcineurin; Cardiac hypertrophy; Endothelin 1; Nuclear factor of activated T cell; Peroxisome proliferator activated receptor gamma

Indexed keywords

CALCINEURIN; ENDOTHELIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ROSIGLITAZONE; TRANSCRIPTION FACTOR NFAT;

EID: 53149117031     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-008-9848-8     Document Type: Article
Times cited : (42)

References (39)
  • 1
    • 0031798873 scopus 로고    scopus 로고
    • Calcineurin - The missing link in cardiac hypertrophy
    • doi: 10.1038/nm0698-661
    • Izumo S, Aoki H (1998) Calcineurin - the missing link in cardiac hypertrophy. Nat Med 4:661-662. doi: 10.1038/nm0698-661
    • (1998) Nat Med , vol.4 , pp. 661-662
    • Izumo, S.1    Aoki, H.2
  • 2
    • 11144310564 scopus 로고    scopus 로고
    • An overview on biological mechanisms of PPARs
    • doi: 10.1016/j.phrs.2004.07.012
    • Kota BP, Huang TH-W, Roufogalis BD (2005) An overview on biological mechanisms of PPARs. Pharmacol Res 51:85-94. doi: 10.1016/ j.phrs.2004.07.012
    • (2005) Pharmacol Res , vol.51 , pp. 85-94
    • Kota, B.P.1    Huang, T.H.-W.2    Roufogalis, B.D.3
  • 3
    • 0033546190 scopus 로고    scopus 로고
    • Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12,14-prostaglandin J2
    • doi: 10.1074/jbc.274.24.17042
    • Bishop-Bailey D, Hla T (1999) Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12,14-prostaglandin J2. J Biol Chem 274:17042-17048. doi: 10.1074/jbc.274.24.17042
    • (1999) J Biol Chem , vol.274 , pp. 17042-17048
    • Bishop-Bailey, D.1    Hla, T.2
  • 4
    • 0037076294 scopus 로고    scopus 로고
    • Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats role of peroxisome proliferator-activated receptor-γ
    • doi: 10.1161/01.CIR.0000016049.86468.23
    • Diep QN, Mabrouk ME, Cohn JS et al (2002) Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats role of peroxisome proliferator-activated receptor-γ. Circulation 105:2296-2302. doi: 10.1161/ 01.CIR.0000016049.86468.23
    • (2002) Circulation , vol.105 , pp. 2296-2302
    • Diep, Q.N.1    Mabrouk, M.E.2    Cohn, J.S.3
  • 5
    • 0036670238 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ activators inhibit endothelin-1-related cardiac hypertrophy in rats
    • Sakai S, Miyauchi T, Irukayama-Tomobe Y et al (2002) Peroxisome proliferator-activated receptor-γ activators inhibit endothelin-1-related cardiac hypertrophy in rats. Clin Sci 103:16S-20S
    • (2002) Clin Sci , vol.103
    • Sakai, S.1    Miyauchi, T.2    Irukayama-Tomobe, Y.3
  • 6
    • 0037066014 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo
    • doi: 10.1161/hc1002.105225
    • Asakawa M, Takano H, Nagai T et al (2002) Peroxisome proliferator-activated receptor γ plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo. Circulation 105:1240-1246. doi: 10.1161/hc1002.105225
    • (2002) Circulation , vol.105 , pp. 1240-1246
    • Asakawa, M.1    Takano, H.2    Nagai, T.3
  • 7
    • 13544270029 scopus 로고    scopus 로고
    • Long-term effects of the PPARγ activator pioglitazone on cardiac inflammation in stroke prone spontaneously hypertensive rats
    • doi: 10.1139/y04-094
    • Diep QN, Amiri F, Benkirane K et al (2004) Long-term effects of the PPARγ activator pioglitazone on cardiac inflammation in stroke prone spontaneously hypertensive rats. Can J Physiol Pharmacol 82:976-985. doi: 10.1139/y04-094
    • (2004) Can J Physiol Pharmacol , vol.82 , pp. 976-985
    • Diep, Q.N.1    Amiri, F.2    Benkirane, K.3
  • 8
    • 0035797865 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ activators inhibit cardiac hypertrophy in cardiac myocytes
    • doi: 10.1161/hc4001.097186
    • Yamamoto K, Ohki R, Lee RT et al (2001) Peroxisome proliferator-activated receptor γ activators inhibit cardiac hypertrophy in cardiac myocytes. Circulation 104:1670-1675. doi: 10.1161/ hc4001.097186
    • (2001) Circulation , vol.104 , pp. 1670-1675
    • Yamamoto, K.1    Ohki, R.2    Lee, R.T.3
  • 9
    • 0032540267 scopus 로고    scopus 로고
    • A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
    • doi: 10.1016/S0092-8674(00)81573-1
    • Molkentin JD, Lu J-R, Antos CL et al (1998) A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93:215-228. doi: 10.1016/S0092-8674(00)81573-1
    • (1998) Cell , vol.93 , pp. 215-228
    • Molkentin, J.D.1    Lu, J.-R.2    Antos, C.L.3
  • 10
    • 0034607990 scopus 로고    scopus 로고
    • 2-terminal kinase activation in the heart
    • doi: 10.1074/jbc.275.18.13571
    • 2-terminal kinase activation in the heart. J Biol Chem 275:13571-13579. doi: 10.1074/jbc.275.18.13571
    • (2000) J Biol Chem , vol.275 , pp. 13571-13579
    • Windt, L.J.D.1    Lim, H.W.2    Haq, S.3
  • 11
    • 3242770551 scopus 로고    scopus 로고
    • 2+-calcineurin-NFAT cascade in cardiac myocytes
    • doi: 10.1016/j.cardiores.2004.04.002
    • 2+-calcineurin-NFAT cascade in cardiac myocytes. Cardiovasc Res 63:450-457. doi: 10.1016/ j.cardiores.2004.04.002
    • (2004) Cardiovasc Res , vol.63 , pp. 450-457
    • Fiedler, B.1    Wollert, K.C.2
  • 12
    • 0035800041 scopus 로고    scopus 로고
    • Calcineurin plays a critical role in the development of pressure overload-induced cardiac hypertrophy
    • doi: 10.1161/hc2601.090987
    • Zou Y, Hiroi Y, Uozumi H et al (2001) Calcineurin plays a critical role in the development of pressure overload-induced cardiac hypertrophy. Circulation 104:97-101. doi: 10.1161/hc2601.090987
    • (2001) Circulation , vol.104 , pp. 97-101
    • Zou, Y.1    Hiroi, Y.2    Uozumi, H.3
  • 13
    • 4444382387 scopus 로고    scopus 로고
    • Calcium-calcineurin signaling in the regulation of cardiac hypertrophy
    • doi: 10.1016/j.bbrc.2004.07.121
    • Wilkins BJ, Molkentin JD (2004) Calcium-calcineurin signaling in the regulation of cardiac hypertrophy. Biochem Biophys Res Commun 322:1178-1191. doi: 10.1016/j.bbrc.2004.07.121
    • (2004) Biochem Biophys Res Commun , vol.322 , pp. 1178-1191
    • Wilkins, B.J.1    Molkentin, J.D.2
  • 14
    • 0142210174 scopus 로고    scopus 로고
    • 4+ T cells by PPAR-γ ligands: Involvement of physical association between PPAR-γ and the nuclear factor of activated T cells transcription factor
    • doi: 10.1124/mol.64.5.1169
    • 4+ T cells by PPAR-γ ligands: Involvement of physical association between PPAR-γ and the nuclear factor of activated T cells transcription factor. Mol Pharmacol 64:1169-1179. doi: 10.1124/mol.64.5.1169
    • (2003) Mol Pharmacol , vol.64 , pp. 1169-1179
    • Chung, S.W.1    Kang, B.Y.2    Kim, T.S.3
  • 15
    • 33845609092 scopus 로고    scopus 로고
    • Prostaglandin F2α inhibits adipocyte differentiation via a Gαq-calcium-calcineurin-dependent signaling pathway
    • doi: 10.1002/jcb.21044
    • Liu L, Clipstone NA (2007) Prostaglandin F2α inhibits adipocyte differentiation via a Gαq-calcium-calcineurin-dependent signaling pathway. J Cell Biochem 100:161-173. doi: 10.1002/jcb.21044
    • (2007) J Cell Biochem , vol.100 , pp. 161-173
    • Liu, L.1    Clipstone, N.A.2
  • 16
    • 0036094148 scopus 로고    scopus 로고
    • Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases
    • doi: 10.1128/MCB.22.11.3892-3904.2002
    • Yang TTC, Xiong Q, Enslen H et al (2002) Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases. Mol Cell Biol 22:3892-3904. doi: 10.1128/MCB.22.11.3892-3904.2002
    • (2002) Mol Cell Biol , vol.22 , pp. 3892-3904
    • Yang, T.T.C.1    Xiong, Q.2    Enslen, H.3
  • 17
    • 0034057069 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in the cardiovascular system
    • doi: 10.1038/sj.bjp.0703149
    • Bishop-Bailey D (2000) Peroxisome proliferator-activated receptors in the cardiovascular system. Br J Pharmacol 129:823-834. doi: 10.1038/ sj.bjp.0703149
    • (2000) Br J Pharmacol , vol.129 , pp. 823-834
    • Bishop-Bailey, D.1
  • 18
    • 33745511754 scopus 로고    scopus 로고
    • An optimized protocol for culture of cardiomyocyte from neonatal rat
    • doi: 10.1007/s10616-006-6334-6
    • Fu JJ, Gao J, Pi RB et al (2005) An optimized protocol for culture of cardiomyocyte from neonatal rat. Cytotechnology 49:109-116. doi: 10.1007/ s10616-006-6334-6
    • (2005) Cytotechnology , vol.49 , pp. 109-116
    • Fu, J.J.1    Gao, J.2    Pi, R.B.3
  • 19
    • 31644436468 scopus 로고    scopus 로고
    • C333H, a novel PPARα/γ dual agonist, has beneficial effects on insulin resistance and lipid metabolism
    • doi: 10.1111/j.1745-7254.2006.00263.x
    • Xu C, Wang L, Liu H et al (2006) C333H, a novel PPARα/γ dual agonist, has beneficial effects on insulin resistance and lipid metabolism. Acta Pharmacol Sin 27:223-228. doi: 10.1111/ j.1745-7254.2006.00263.x
    • (2006) Acta Pharmacol Sin , vol.27 , pp. 223-228
    • Xu, C.1    Wang, L.2    Liu, H.3
  • 20
    • 9944219987 scopus 로고    scopus 로고
    • Neuropeptide Y induces cardiomyocyte hypertrophy via calcineurin signaling in rats
    • doi: 10.1016/j.regpep. 2004.07.034
    • Chena M, Lia X, Dongb Q et al (2005) Neuropeptide Y induces cardiomyocyte hypertrophy via calcineurin signaling in rats. Regul Pept 125:9-15. doi: 10.1016/j.regpep. 2004.07.034
    • (2005) Regul Pept , vol.125 , pp. 9-15
    • Chena, M.1    Lia, X.2    Dongb, Q.3
  • 21
    • 17444404892 scopus 로고    scopus 로고
    • 14-3-3 Proteins regulate glycogen synthase 3beta phosphorylation and inhibit cardiomyocyte hypertrophy
    • doi: 10.1111/j.1742-4658.2005.04614.x
    • Liao W, Wang S, Han C et al (2005) 14-3-3 Proteins regulate glycogen synthase 3beta phosphorylation and inhibit cardiomyocyte hypertrophy. FEBS J 272:1845-1854. doi: 10.1111/j.1742-4658.2005.04614.x
    • (2005) FEBS J , vol.272 , pp. 1845-1854
    • Liao, W.1    Wang, S.2    Han, C.3
  • 22
    • 33847372100 scopus 로고    scopus 로고
    • Upregulation of TRPC1 in the development of cardiac hypertrophy
    • doi: 10.1016/j.yjmcc.2006.10.020
    • Takayoshi O, Hiroyuki W, Manabu M et al (2007) Upregulation of TRPC1 in the development of cardiac hypertrophy. J Mol Cell Cardiol 42:498-507. doi: 10.1016/j.yjmcc.2006.10.020
    • (2007) J Mol Cell Cardiol , vol.42 , pp. 498-507
    • Takayoshi, O.1    Hiroyuki, W.2    Manabu, M.3
  • 23
    • 36049031562 scopus 로고    scopus 로고
    • Imbalance between CaM kinase II and calcineurin activities impairs caffeine-induced calcium release in hypertrophic cardiomyocytes
    • doi: 10.1016/j.bcp. 2007.08.022
    • Lu Y, Shioda N, Han F et al (2007) Imbalance between CaM kinase II and calcineurin activities impairs caffeine-induced calcium release in hypertrophic cardiomyocytes. Biochem Pharmacol 74:1727-1737. doi: 10.1016/j.bcp. 2007.08.022
    • (2007) Biochem Pharmacol , vol.74 , pp. 1727-1737
    • Lu, Y.1    Shioda, N.2    Han, F.3
  • 24
    • 34250816262 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-α prevents glycogen synthase 3β phosphorylation and inhibits cardiac hypertrophy
    • doi: 10.1016/j.febslet.2007.06.017
    • Li R, Zheng W, Pi R et al (2007) Activation of peroxisome proliferator-activated receptor-α prevents glycogen synthase 3β phosphorylation and inhibits cardiac hypertrophy. FEBS Lett 581:3311-3316. doi: 10.1016/j.febslet.2007.06.017
    • (2007) FEBS Lett , vol.581 , pp. 3311-3316
    • Li, R.1    Zheng, W.2    Pi, R.3
  • 25
    • 3242753501 scopus 로고    scopus 로고
    • Negative regulators of cardiac hypertrophy
    • doi: 10.1016/j.cardiores.2004.03.015
    • Hardta SE, Sadoshima J (2004) Negative regulators of cardiac hypertrophy. Cardiovasc Res 63:500-509. doi: 10.1016/ j.cardiores.2004.03.015
    • (2004) Cardiovasc Res , vol.63 , pp. 500-509
    • Hardta, S.E.1    Sadoshima, J.2
  • 26
    • 18444412555 scopus 로고    scopus 로고
    • Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662
    • doi: 10.1021/bi0159581
    • Leesnitzer LM, Parks DJ, Bledsoe RK et al (2002) Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662. Biochemistry 41:6640-6650. doi: 10.1021/bi0159581
    • (2002) Biochemistry , vol.41 , pp. 6640-6650
    • Leesnitzer, L.M.1    Parks, D.J.2    Bledsoe, R.K.3
  • 27
    • 34248580190 scopus 로고    scopus 로고
    • Does the inhibition of c-myc expression mediate the anti-tumor activity of PPAR's ligands in prostate cancer cell lines?
    • doi: 10.1016/j.abb.2007.03.013
    • Laidler P, Dulińska J, Mrozicki S (2007) Does the inhibition of c-myc expression mediate the anti-tumor activity of PPAR's ligands in prostate cancer cell lines? Arch Biochem Biophys 462:1-12. doi: 10.1016/ j.abb.2007.03.013
    • (2007) Arch Biochem Biophys , vol.462 , pp. 1-12
    • Laidler, P.1    Dulińska, J.2    Mrozicki, S.3
  • 28
    • 2442711384 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and atherogenesis regulators of gene expression in vascular cells
    • doi: 10.1161/01.RES.0000127122.22685.0A
    • Marx N, Duez H, Fruchart J-C et al (2004) Peroxisome proliferator-activated receptors and atherogenesis regulators of gene expression in vascular cells. Circ Res 94:1168-1178. doi: 10.1161/ 01.RES.0000127122.22685.0A
    • (2004) Circ Res , vol.94 , pp. 1168-1178
    • Marx, N.1    Duez, H.2    Fruchart, J.-C.3
  • 29
    • 0034625078 scopus 로고    scopus 로고
    • Calcineurin is activated in rat hearts with physiological left ventricular hypertrophy induced by voluntary exercise training
    • Eto Y, Yonekura K, Sonoda M et al (2000) Calcineurin is activated in rat hearts with physiological left ventricular hypertrophy induced by voluntary exercise training. Circulation 101:2134-2137
    • (2000) Circulation , vol.101 , pp. 2134-2137
    • Eto, Y.1    Yonekura, K.2    Sonoda, M.3
  • 30
    • 0034680328 scopus 로고    scopus 로고
    • Calcineurin inhibitor attenuates the development and induces the regression of cardiac hypertrophy in rats with salt-sensitive hypertension
    • Shimoyama M, Hayashi D, Zou Y et al (2000) Calcineurin inhibitor attenuates the development and induces the regression of cardiac hypertrophy in rats with salt-sensitive hypertension. Circulation 102:1996-2004
    • (2000) Circulation , vol.102 , pp. 1996-2004
    • Shimoyama, M.1    Hayashi, D.2    Zou, Y.3
  • 31
    • 0037065888 scopus 로고    scopus 로고
    • Calcineurin inhibition attenuates mineralocorticoid-induced cardiac hypertrophy
    • doi: 10.1161/hc0602.104675
    • Takeda Y, Yoneda T, Demura M et al (2002) Calcineurin inhibition attenuates mineralocorticoid-induced cardiac hypertrophy. Circulation 105:677-679. doi: 10.1161/hc0602.104675
    • (2002) Circulation , vol.105 , pp. 677-679
    • Takeda, Y.1    Yoneda, T.2    Demura, M.3
  • 32
    • 10744223962 scopus 로고    scopus 로고
    • Roles of calcineurin and calcium/calmodulin-dependent protein kinase II in pressure overload-induced cardiac hypertrophy
    • doi: 10.1016/S0022-2828(03)00234-7
    • Saito T, Fukuzawa J, Osaki J et al (2003) Roles of calcineurin and calcium/calmodulin-dependent protein kinase II in pressure overload-induced cardiac hypertrophy. J Mol Cell Cardiol 35:1153-1160. doi: 10.1016/S0022-2828(03)00234-7
    • (2003) J Mol Cell Cardiol , vol.35 , pp. 1153-1160
    • Saito, T.1    Fukuzawa, J.2    Osaki, J.3
  • 33
    • 0033054549 scopus 로고    scopus 로고
    • Calcineurin and human heart failure
    • doi: 10.1038/6430
    • Lim HW, Molkentin JD (1999) Calcineurin and human heart failure. Nat Med 5:246-247. doi: 10.1038/6430
    • (1999) Nat Med , vol.5 , pp. 246-247
    • Lim, H.W.1    Molkentin, J.D.2
  • 34
    • 0037076286 scopus 로고    scopus 로고
    • Calcineurin in human heart hypertrophy
    • doi: 10.1161/01.CIR.0000016044.19527.96
    • Ritter O, Hack S, Schuh K et al (2002) Calcineurin in human heart hypertrophy. Circulation 105:2265-2269. doi: 10.1161/ 01.CIR.0000016044.19527.96
    • (2002) Circulation , vol.105 , pp. 2265-2269
    • Ritter, O.1    Hack, S.2    Schuh, K.3
  • 35
    • 3242772151 scopus 로고    scopus 로고
    • Calcineurin-NFAT signaling regulates the cardiac hypertrophic response in coordination with the MAPKs
    • doi: 10.1016/j.cardiores.2004.01.021
    • Molkentin JD (2004) Calcineurin-NFAT signaling regulates the cardiac hypertrophic response in coordination with the MAPKs. Cardiovasc Res 63:467-475. doi: 10.1016/j.cardiores.2004.01.021
    • (2004) Cardiovasc Res , vol.63 , pp. 467-475
    • Molkentin, J.D.1
  • 36
    • 0141483523 scopus 로고    scopus 로고
    • Transcriptional regulation by calcium, calcineurin, and NFAT
    • doi: 10.1101/gad.1102703
    • Hogan PG, Chen L, Nardone J et al (2003) Transcriptional regulation by calcium, calcineurin, and NFAT. Genes Dev 17:2205-2232. doi: 10.1101/ gad.1102703
    • (2003) Genes Dev , vol.17 , pp. 2205-2232
    • Hogan, P.G.1    Chen, L.2    Nardone, J.3
  • 37
    • 33748742074 scopus 로고    scopus 로고
    • Inhibition of nuclear import of calcineurin prevents myocardial hypertrophy
    • doi: 10.1161/01.RES.0000243208.59795.d8
    • Hallhuber M, Burkard N, Wu R et al (2006) Inhibition of nuclear import of calcineurin prevents myocardial hypertrophy. Circ Res 99:626-635. doi: 10.1161/01.RES.0000243208.59795.d8
    • (2006) Circ Res , vol.99 , pp. 626-635
    • Hallhuber, M.1    Burkard, N.2    Wu, R.3
  • 38
    • 0040141604 scopus 로고    scopus 로고
    • A role for the p38 MAP kinase pathway in the nuclear shuttling of NFATp
    • doi: 10.1074/jbc.275.18.13872
    • PGd Arco, Martínez-Martínez S, Maldonado JL et al (2000) A role for the p38 MAP kinase pathway in the nuclear shuttling of NFATp. J Biol Chem 275:13872-13878. doi: 10.1074/jbc.275.18.13872
    • (2000) J Biol Chem , vol.275 , pp. 13872-13878
    • PGd Arco Martínez-Martínez, S.1    Maldonado, J.L.2
  • 39
    • 0001297403 scopus 로고    scopus 로고
    • Activation of human T lymphocytes is inhibited by peroxisome proliferator activated receptorγ (PPARγ) agonists. PPARγ co-association with transcription factor NFAT
    • doi: 10.1074/jbc.275.7.4541
    • Yang XY, Wang LH, Chen T et al (2000) Activation of human T lymphocytes is inhibited by peroxisome proliferator activated receptorγ (PPARγ) agonists. PPARγ co-association with transcription factor NFAT. J Biol Chem 275:4541-4544. doi: 10.1074/jbc.275.7.4541
    • (2000) J Biol Chem , vol.275 , pp. 4541-4544
    • Yang, X.Y.1    Wang, L.H.2    Chen, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.