Structural basis for toxin resistance of β4-associated calcium-activated potassium (BK) channels

Journal of Biological Chemistry

Volumn 283, Issue 35, 2008, Pages 24177-24184

  Gan, Geliang ^a   Yi, Hong ^b   Chen, Maorong ^a   Sun, Liang ^a   Li, Wenxin ^b   Wu, Yingliang ^b   Ding, Jiuping ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING ENERGY; CALCIUM; FLOW INTERACTIONS; POTASSIUM;

CHANNEL INHIBITORS; CHANNEL PORES; ELECTROSTATIC INTERACTIONS; EXPERIMENTAL METHODS; EXTERNAL-; FUNCTIONAL DIVERSITIES; LIMITED SPACES; OPEN CONFORMATIONS; STRUCTURAL BASES;

BINDING SITES;

CALCIUM ACTIVATED POTASSIUM BETA4; CALCIUM ACTIVATED POTASSIUM CHANNEL; CHARYBDOTOXIN; TOXIN; TYROSINE; UNCLASSIFIED DRUG; KCNMA1 PROTEIN, HUMAN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNIT; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL BETA SUBUNIT; NEUROTOXIN;

ALPHA CHAIN; ARTICLE; BETA CHAIN; BINDING SITE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ELECTRICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; CELL LINE; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; PROTEIN BINDING; PROTEIN QUATERNARY STRUCTURE;

CELL LINE; CHARYBDOTOXIN; ELECTROSTATICS; HUMANS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNITS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL BETA SUBUNITS; MUTAGENESIS, INSERTIONAL; MUTATION; NEUROTOXINS; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY;

EID: 53049107758     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M800179200     Document Type: Article

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