메뉴 건너뛰기




Volumn 68, Issue 16, 2008, Pages 6851-6858

Platelet granule secretion continuously prevents intratumor hemorrhage

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 1; GLYCOPROTEIN IB ALPHA; INTEGRIN; PADGEM PROTEIN; SEROTONIN; VON WILLEBRAND FACTOR; AGPT PROTEIN, MOUSE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HEMOGLOBIN; METALLOPROTEINASE; O SIALOGLYCOPROTEIN ENDOPEPTIDASE; O-SIALOGLYCOPROTEIN ENDOPEPTIDASE; RASGRP2 PROTEIN, MOUSE; THROMBIN RECEPTOR; VASCULAR ENDOTHELIAL GROWTH FACTOR A, MOUSE; VASCULOTROPIN A;

EID: 53049093114     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-0718     Document Type: Article
Times cited : (195)

References (58)
  • 1
    • 0001506871 scopus 로고
    • Phlegmatia alba dolens
    • Paris: JB Baillere et Fils;
    • Trousseau A. Phlegmatia alba dolens. Clinique Medicale de l'Hotel-Dieu de Paris. Vol. 3. Paris: JB Baillere et Fils; 1865. p. 654-712.
    • (1865) Clinique Medicale de l'Hotel-Dieu de Paris , vol.3 , pp. 654-712
    • Trousseau, A.1
  • 2
    • 0023132474 scopus 로고
    • Tissue factor activity in leukemia cells. Special reference to disseminated intravascular coagulation
    • Andoh K, Kubota T, Takada M, Tanaka H, Kobayashi N, Maekawa T. Tissue factor activity in leukemia cells. Special reference to disseminated intravascular coagulation. Cancer 1987;59:748-54.
    • (1987) Cancer , vol.59 , pp. 748-754
    • Andoh, K.1    Kubota, T.2    Takada, M.3    Tanaka, H.4    Kobayashi, N.5    Maekawa, T.6
  • 3
    • 0030045936 scopus 로고    scopus 로고
    • Falanga A, Marchetti M, Giovanelli S, Barbui T. All-trans-retinoic acid counteracts endothelial cell procoagulant activity induced by a human promyelocytic leukemia-derived cell line (NB4). Blood 1996;87:613-7.
    • Falanga A, Marchetti M, Giovanelli S, Barbui T. All-trans-retinoic acid counteracts endothelial cell procoagulant activity induced by a human promyelocytic leukemia-derived cell line (NB4). Blood 1996;87:613-7.
  • 4
    • 0028807597 scopus 로고
    • Effects of dexamethasone on pro-inflammatory cytokine expression, cell growth and maturation during granulocytic differentiation of acute promyelocytic leukemia cells
    • Gianni M, Norio P, Terao M, et al. Effects of dexamethasone on pro-inflammatory cytokine expression, cell growth and maturation during granulocytic differentiation of acute promyelocytic leukemia cells. Eur Cytokine Netw 1995;6:157-65.
    • (1995) Eur Cytokine Netw , vol.6 , pp. 157-165
    • Gianni, M.1    Norio, P.2    Terao, M.3
  • 5
    • 33747871452 scopus 로고    scopus 로고
    • Tumor-derived matrix metalloproteinase-1 targets endothelial proteinase-activated receptor 1 promoting endothelial cell activation
    • Goerge T, Barg A, Schnaeker EM, et al. Tumor-derived matrix metalloproteinase-1 targets endothelial proteinase-activated receptor 1 promoting endothelial cell activation. Cancer Res 2006;66:7766-74.
    • (2006) Cancer Res , vol.66 , pp. 7766-7774
    • Goerge, T.1    Barg, A.2    Schnaeker, E.M.3
  • 6
    • 36448970114 scopus 로고    scopus 로고
    • Non-uniform plasma leakage affects local hematocrit and blood flow: Implications for inflammation and tumor perfusion
    • Sun C, Jain RK, Munn LL. Non-uniform plasma leakage affects local hematocrit and blood flow: implications for inflammation and tumor perfusion. Ann Biomed Eng 2007;35:2121-9.
    • (2007) Ann Biomed Eng , vol.35 , pp. 2121-2129
    • Sun, C.1    Jain, R.K.2    Munn, L.L.3
  • 7
    • 20244379858 scopus 로고
    • Vascular permeability factor, fibrin, and the pathogenesis of tumor stroma formation
    • Dvorak HF, Nagy JA, Berse B, et al. Vascular permeability factor, fibrin, and the pathogenesis of tumor stroma formation. Ann N Y Acad Sci 1992;667:101-11.
    • (1992) Ann N Y Acad Sci , vol.667 , pp. 101-111
    • Dvorak, H.F.1    Nagy, J.A.2    Berse, B.3
  • 8
    • 0034307371 scopus 로고    scopus 로고
    • Identification of critical antigenspecific mechanisms in the development of immune thrombocytopenic purpura in mice
    • Nieswandt B, Bergmeier W, Rackebrandt K, Gessner JE, Zirngibl H. Identification of critical antigenspecific mechanisms in the development of immune thrombocytopenic purpura in mice. Blood 2000;96:2520-7.
    • (2000) Blood , vol.96 , pp. 2520-2527
    • Nieswandt, B.1    Bergmeier, W.2    Rackebrandt, K.3    Gessner, J.E.4    Zirngibl, H.5
  • 9
    • 0020661638 scopus 로고
    • The effect of thrombocytopenia and antiserotonin treatment on the lodgement of circulating tumor cells. A vital fluorescence microscopic, electron microscopic and isotope study in the rat
    • Skolnik G, Ericson LE, Bagge U. The effect of thrombocytopenia and antiserotonin treatment on the lodgement of circulating tumor cells. A vital fluorescence microscopic, electron microscopic and isotope study in the rat. J Cancer Res Clin Oncol 1983;105:30-7.
    • (1983) J Cancer Res Clin Oncol , vol.105 , pp. 30-37
    • Skolnik, G.1    Ericson, L.E.2    Bagge, U.3
  • 10
    • 0029153853 scopus 로고
    • Role of platelets, thrombin, integrin IIb-IIIa, fibronectin and von Willebrand factor on tumor adhesion in vitro and metastasis in vivo
    • Nierodzik ML, Klepfish A, Karpatkin S. Role of platelets, thrombin, integrin IIb-IIIa, fibronectin and von Willebrand factor on tumor adhesion in vitro and metastasis in vivo. Thromb Haemost 1995;74:282-90.
    • (1995) Thromb Haemost , vol.74 , pp. 282-290
    • Nierodzik, M.L.1    Klepfish, A.2    Karpatkin, S.3
  • 11
    • 34547448302 scopus 로고    scopus 로고
    • Platelet glycoprotein Ibα supports experimental lung metastasis
    • Jain S, Zuka M, Liu J, et al. Platelet glycoprotein Ibα supports experimental lung metastasis. Proc Natl Acad Sci U S A 2007;104:9024-8.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 9024-9028
    • Jain, S.1    Zuka, M.2    Liu, J.3
  • 12
    • 0031742776 scopus 로고    scopus 로고
    • Evidence that platelets promote tube formation by endothelial cells on matrigel
    • Pipili-Synetos E, Papadimitriou E, Maragoudakis ME. Evidence that platelets promote tube formation by endothelial cells on matrigel. Br J Pharmacol 1998;125:1252-7.
    • (1998) Br J Pharmacol , vol.125 , pp. 1252-1257
    • Pipili-Synetos, E.1    Papadimitriou, E.2    Maragoudakis, M.E.3
  • 13
    • 0037044403 scopus 로고    scopus 로고
    • Angiogenesis by implantation of peripheral blood mononuclear cells and platelets into ischemic limbs
    • Iba O, Matsubara H, Nozawa Y, et al. Angiogenesis by implantation of peripheral blood mononuclear cells and platelets into ischemic limbs. Circulation 2002;106:2019-25.
    • (2002) Circulation , vol.106 , pp. 2019-2025
    • Iba, O.1    Matsubara, H.2    Nozawa, Y.3
  • 14
    • 0031029290 scopus 로고    scopus 로고
    • Constitutive production and thromb in-induced release of vascular endothelial growth factor by human megakaryocytes and platelets
    • Mohle R, Green D, Moore MA, Nachman RL, Rafii S. Constitutive production and thromb in-induced release of vascular endothelial growth factor by human megakaryocytes and platelets. Proc Natl Acad Sci U S A 1997; 94:663-8.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 663-668
    • Mohle, R.1    Green, D.2    Moore, M.A.3    Nachman, R.L.4    Rafii, S.5
  • 15
    • 0019540347 scopus 로고
    • Plateletderived growth factor. Isolation by a large-scale procedure and analysis of subunit composition
    • Heldin CH, Westermark B, Wasteson A. Plateletderived growth factor. Isolation by a large-scale procedure and analysis of subunit composition. Biochem J 1981;193:907-13.
    • (1981) Biochem J , vol.193 , pp. 907-913
    • Heldin, C.H.1    Westermark, B.2    Wasteson, A.3
  • 17
    • 0025037290 scopus 로고
    • Megakaryocyte synthesis is the source of epidermal growth factor in human platelets
    • Ben-Ezra J, Sheibani K, Hwang DL, Lev-Ran A. Megakaryocyte synthesis is the source of epidermal growth factor in human platelets. Am J Pathol 1990;137:755-9.
    • (1990) Am J Pathol , vol.137 , pp. 755-759
    • Ben-Ezra, J.1    Sheibani, K.2    Hwang, D.L.3    Lev-Ran, A.4
  • 18
    • 0022297755 scopus 로고
    • Inhibitory effect of transforming growth factor-β on DNA synthesis of adult rat hepatocytes in primary culture
    • Nakamura T, Tomita Y, Hirai R, Yamaoka K, Kaji K, Ichihara A. Inhibitory effect of transforming growth factor-β on DNA synthesis of adult rat hepatocytes in primary culture. Biochem Biophys Res Commun 1985; 133:1042-50.
    • (1985) Biochem Biophys Res Commun , vol.133 , pp. 1042-1050
    • Nakamura, T.1    Tomita, Y.2    Hirai, R.3    Yamaoka, K.4    Kaji, K.5    Ichihara, A.6
  • 19
    • 0024382745 scopus 로고
    • Human platelet-derived mitogens. I. Identification of insulinlike growth factors I and II by purification and N a amino acid sequence analysis
    • Karey KP, Marquardt H, Sirbasku DA. Human platelet-derived mitogens. I. Identification of insulinlike growth factors I and II by purification and N a amino acid sequence analysis. Blood 1989;74:1084-92.
    • (1989) Blood , vol.74 , pp. 1084-1092
    • Karey, K.P.1    Marquardt, H.2    Sirbasku, D.A.3
  • 20
    • 0035125737 scopus 로고    scopus 로고
    • Thrombin induces the release of angiopoietin-1 from platelets
    • Li JJ, Huang YQ, Basch R, Karpatkin S. Thrombin induces the release of angiopoietin-1 from platelets. Thromb Haemost 2001;85:204-6.
    • (2001) Thromb Haemost , vol.85 , pp. 204-206
    • Li, J.J.1    Huang, Y.Q.2    Basch, R.3    Karpatkin, S.4
  • 21
    • 0033738368 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between hemostasis and angiogenesis
    • English D, Welch Z, Kovala AT, et al. Sphingosine 1-phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between hemostasis and angiogenesis. FASEB J 2000;14:2255-65.
    • (2000) FASEB J , vol.14 , pp. 2255-2265
    • English, D.1    Welch, Z.2    Kovala, A.T.3
  • 22
    • 0037205285 scopus 로고    scopus 로고
    • Outside-in signals delivered by matrix metalloproteinase-1 regulate platelet function
    • Galt SW, Lindemann S, Allen L, et al. Outside-in signals delivered by matrix metalloproteinase-1 regulate platelet function. Circ Res 2002;90:1093-9.
    • (2002) Circ Res , vol.90 , pp. 1093-1099
    • Galt, S.W.1    Lindemann, S.2    Allen, L.3
  • 23
    • 0020657751 scopus 로고
    • Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets
    • McLaren KM. Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets. J Clin Pathol 1983;36:197-9.
    • (1983) J Clin Pathol , vol.36 , pp. 197-199
    • McLaren, K.M.1
  • 24
    • 0025166396 scopus 로고
    • Inhibition of angiogenesis by recombinant human platelet factor-4 and related peptides
    • Maione TE, Gray GS, Petro J, et al. Inhibition of angiogenesis by recombinant human platelet factor-4 and related peptides. Science 1990;247:77-9.
    • (1990) Science , vol.247 , pp. 77-79
    • Maione, T.E.1    Gray, G.S.2    Petro, J.3
  • 26
    • 0035933056 scopus 로고    scopus 로고
    • Platelets modulate gastric ulcer healing: Role of endostatin and vascular endothelial growth factor release
    • Ma L, Elliott SN, Cirino G, Buret A, Ignarro LJ, Wallace JL. Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release. Proc Natl Acad Sci U S A 2001;98:6470-5.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 6470-6475
    • Ma, L.1    Elliott, S.N.2    Cirino, G.3    Buret, A.4    Ignarro, L.J.5    Wallace, J.L.6
  • 28
    • 38949178835 scopus 로고    scopus 로고
    • Angiogenesis is regulated by a novel mechanism: Proand antiangiogenic proteins are organized into separate platelet α granules and differentially released
    • Italiano JE, Jr., Richardson JL, Patel-Hett S, et al. Angiogenesis is regulated by a novel mechanism: proand antiangiogenic proteins are organized into separate platelet α granules and differentially released. Blood 2008;111:1227-33.
    • (2008) Blood , vol.111 , pp. 1227-1233
    • Italiano Jr., J.E.1    Richardson, J.L.2    Patel-Hett, S.3
  • 29
    • 32244433234 scopus 로고    scopus 로고
    • Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage
    • Kisucka J, Butterfield CE, Duda DG, et al. Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage. Proc Natl Acad Sci U S A 2006;103:855-60.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 855-860
    • Kisucka, J.1    Butterfield, C.E.2    Duda, D.G.3
  • 30
    • 33645540605 scopus 로고    scopus 로고
    • Pharmacologic inhibition of platelet vWF-GPIbα interaction prevents coronary artery thrombosis
    • Hennan JK, Swillo RE, Morgan GA, et al. Pharmacologic inhibition of platelet vWF-GPIbα interaction prevents coronary artery thrombosis. Thromb Haemost 2006;95:469-75.
    • (2006) Thromb Haemost , vol.95 , pp. 469-475
    • Hennan, J.K.1    Swillo, R.E.2    Morgan, G.A.3
  • 31
    • 0026459493 scopus 로고
    • Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fluid pressure during early growth of human adenocarcinoma LS174T in SCID mice
    • Leunig M, Yuan F, Menger MD, et al. Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fluid pressure during early growth of human adenocarcinoma LS174T in SCID mice. Cancer Res 1992; 52:6553-60.
    • (1992) Cancer Res , vol.52 , pp. 6553-6560
    • Leunig, M.1    Yuan, F.2    Menger, M.D.3
  • 32
    • 0035816654 scopus 로고    scopus 로고
    • Rhodocytin (aggretin) activates platelets lacking α(2)β(1) integrin, glycoprotein VI, and the ligand-binding domain of glycoprotein Ibα
    • Bergmeier W, Bouvard D, Eble JA, et al. Rhodocytin (aggretin) activates platelets lacking α(2)β(1) integrin, glycoprotein VI, and the ligand-binding domain of glycoprotein Ibα. J Biol Chem 2001;276:25121-6.
    • (2001) J Biol Chem , vol.276 , pp. 25121-25126
    • Bergmeier, W.1    Bouvard, D.2    Eble, J.A.3
  • 33
    • 0032483024 scopus 로고    scopus 로고
    • A mouse model of severe von Willebrand disease: Defects in hemostasis and thrombosis
    • Denis C, Methia N, Frenette PS, et al. A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis. Proc Natl Acad Sci U S A 1998;95:9524-9.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 9524-9529
    • Denis, C.1    Methia, N.2    Frenette, P.S.3
  • 34
    • 0029119149 scopus 로고
    • Platelets roll on stimulated endothelium in vivo: An interaction mediated by endothelial P-selectin
    • Frenette PS, Johnson RC, Hynes RO, Wagner DD. Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin. Proc Natl Acad Sci U S A 1995;92:7450-4.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 7450-7454
    • Frenette, P.S.1    Johnson, R.C.2    Hynes, R.O.3    Wagner, D.D.4
  • 35
    • 4644221351 scopus 로고    scopus 로고
    • CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation
    • Crittenden JR, Bergmeier W, Zhang Y, et al. CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation. Nat Med 2004;10:982-6.
    • (2004) Nat Med , vol.10 , pp. 982-986
    • Crittenden, J.R.1    Bergmeier, W.2    Zhang, Y.3
  • 36
    • 0017889987 scopus 로고
    • First annual Lamport award manuscript. Platelet-endothelial interaction and the maintenance of the microvasculature
    • D'Amore P. First annual Lamport award manuscript. Platelet-endothelial interaction and the maintenance of the microvasculature. Microvasc Res 1978;15:137-45.
    • (1978) Microvasc Res , vol.15 , pp. 137-145
    • D'Amore, P.1
  • 37
    • 0033601357 scopus 로고    scopus 로고
    • Thurston G, Suri C, Smith K, et al. Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1. Science 1999;2863511-4.
    • Thurston G, Suri C, Smith K, et al. Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1. Science 1999;2863511-4.
  • 38
    • 27144476793 scopus 로고    scopus 로고
    • Activated platelets induce Weibel-Paladebody secretion and leukocyte rolling in vivo: Role of P-selectin
    • Dole VS, Bergmeier W, Mitchell HA, Eichenberger SC, Wagner DD. Activated platelets induce Weibel-Paladebody secretion and leukocyte rolling in vivo: role of P-selectin. Blood 2005;106:2334-9.
    • (2005) Blood , vol.106 , pp. 2334-2339
    • Dole, V.S.1    Bergmeier, W.2    Mitchell, H.A.3    Eichenberger, S.C.4    Wagner, D.D.5
  • 39
    • 0029973981 scopus 로고    scopus 로고
    • In vivo tracking of platelets: Circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function
    • Michelson AD, Barnard MR, Hechtman HB, et al. In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function. Proc Natl Acad Sci U S A 1996;93:11877-82.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 11877-11882
    • Michelson, A.D.1    Barnard, M.R.2    Hechtman, H.B.3
  • 40
    • 46749098410 scopus 로고    scopus 로고
    • Inflammation induces hemorrhage in thrombocytopenia
    • Goerge T, Ho-Tin-Noe B, Carbo C, et al. Inflammation induces hemorrhage in thrombocytopenia. Blood 2008; 111:4958-64.
    • (2008) Blood , vol.111 , pp. 4958-4964
    • Goerge, T.1    Ho-Tin-Noe, B.2    Carbo, C.3
  • 41
    • 33645739790 scopus 로고    scopus 로고
    • Tumor stroma and regulation of cancer development
    • Tlsty TD, Coussens LM. Tumor stroma and regulation of cancer development. Annu Rev Pathol 2006;1:119-50.
    • (2006) Annu Rev Pathol , vol.1 , pp. 119-150
    • Tlsty, T.D.1    Coussens, L.M.2
  • 42
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens LM, Werb Z. Inflammation and cancer. Nature 2002;420:860-7.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 43
    • 16644394172 scopus 로고    scopus 로고
    • Endothelial cell barrier regulation by sphingosine 1-phosphate
    • McVerry BJ, Garcia JG. Endothelial cell barrier regulation by sphingosine 1-phosphate. J Cell Biochem 2004;92:1075-85.
    • (2004) J Cell Biochem , vol.92 , pp. 1075-1085
    • McVerry, B.J.1    Garcia, J.G.2
  • 44
    • 0034036689 scopus 로고    scopus 로고
    • Angiopoietin-1 protects the adult vasculature against plasma leakage
    • Thurston G, Rudge JS, Ioffe E, et al. Angiopoietin-1 protects the adult vasculature against plasma leakage. Nat Med 2000;6:460-3.
    • (2000) Nat Med , vol.6 , pp. 460-463
    • Thurston, G.1    Rudge, J.S.2    Ioffe, E.3
  • 45
    • 0037636489 scopus 로고    scopus 로고
    • Role of sphingosine-1 phosphate in the enhancement of endothelial barrier integrity by platelet-released products
    • Schaphorst KL, Chiang E, Jacobs KN, et al. Role of sphingosine-1 phosphate in the enhancement of endothelial barrier integrity by platelet-released products. Am J Physiol Lung Cell Mol Physiol 2003;285:L258-67.
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.285
    • Schaphorst, K.L.1    Chiang, E.2    Jacobs, K.N.3
  • 46
    • 0021163685 scopus 로고
    • Vasoactive agonists prevent erythrocyte extravasation in thrombocytopenic hamsters
    • Shepro D, Welles SL, Hechtman HB. Vasoactive agonists prevent erythrocyte extravasation in thrombocytopenic hamsters. Thromb Res 1984;35:421-30.
    • (1984) Thromb Res , vol.35 , pp. 421-430
    • Shepro, D.1    Welles, S.L.2    Hechtman, H.B.3
  • 47
    • 0037592684 scopus 로고    scopus 로고
    • Angiopoietin-1 inhibits endothelial permeability, neutrophil adherence and IL-8 production
    • Pizurki L, Zhou Z, Glynos K, Roussos C, Papapetropoulos A. Angiopoietin-1 inhibits endothelial permeability, neutrophil adherence and IL-8 production. Br J Pharmacol 2003; 139329-36.
    • (2003) Br J Pharmacol , pp. 139329-139336
    • Pizurki, L.1    Zhou, Z.2    Glynos, K.3    Roussos, C.4    Papapetropoulos, A.5
  • 48
    • 33744904178 scopus 로고    scopus 로고
    • Regulation of endothelin-1 by angiopoietin-1: Implications for inflammation
    • McCarter SD, Lai PF, Suen RS, Stewart DJ. Regulation of endothelin-1 by angiopoietin-1: implications for inflammation. Exp Biol Med (Maywood) 2006;231:985-91.
    • (2006) Exp Biol Med (Maywood) , vol.231 , pp. 985-991
    • McCarter, S.D.1    Lai, P.F.2    Suen, R.S.3    Stewart, D.J.4
  • 49
    • 34248381322 scopus 로고    scopus 로고
    • Cell-based angiopoietin-1 gene therapy for acute lung injury
    • McCarter SD, Mei SH, Lai PF, et al. Cell-based angiopoietin-1 gene therapy for acute lung injury. Am J Respir Crit Care Med 2007;175:1014-26.
    • (2007) Am J Respir Crit Care Med , vol.175 , pp. 1014-1026
    • McCarter, S.D.1    Mei, S.H.2    Lai, P.F.3
  • 50
    • 33751225092 scopus 로고    scopus 로고
    • Angiopoietins: A link between angiogenesis and inflammation
    • Fiedler U, Augustin HG. Angiopoietins: a link between angiogenesis and inflammation. Trends Immunol 2006;27:552-8.
    • (2006) Trends Immunol , vol.27 , pp. 552-558
    • Fiedler, U.1    Augustin, H.G.2
  • 51
    • 0037369264 scopus 로고    scopus 로고
    • Platelet-endothelial interaction in tumor angiogenesis and microcirculation
    • Manegold PC, Hutter J, Pahernik SA, Messmer K, Dellian M. Platelet-endothelial interaction in tumor angiogenesis and microcirculation. Blood 2003;101:1970-6.
    • (2003) Blood , vol.101 , pp. 1970-1976
    • Manegold, P.C.1    Hutter, J.2    Pahernik, S.A.3    Messmer, K.4    Dellian, M.5
  • 53
    • 0025590174 scopus 로고
    • Blood flow, oxygen consumption and tissue oxygenation of human tumors
    • Vaupel P, Kallinowski F, Okunieff P. Blood flow, oxygen consumption and tissue oxygenation of human tumors. Adv Exp Med Biol 1990;277;895-905.
    • (1990) Adv Exp Med Biol , vol.277 , pp. 895-905
    • Vaupel, P.1    Kallinowski, F.2    Okunieff, P.3
  • 54
    • 34447258681 scopus 로고    scopus 로고
    • Tumor microenvironment abnormalities: Causes, consequences, and strategies to normalize
    • Fukumura Dh, Jain RK. Tumor microenvironment abnormalities: causes, consequences, and strategies to normalize. J Cell Biochem 2007;101:937-49.
    • (2007) J Cell Biochem , vol.101 , pp. 937-949
    • Fukumura, D.1    Jain, R.K.2
  • 55
    • 35748970483 scopus 로고    scopus 로고
    • Tumor microvasculature and microenvironment: Targets for anti-angiogenesis and normalization
    • Fukumura D, Jain RK. Tumor microvasculature and microenvironment: targets for anti-angiogenesis and normalization. Microvasc Res 2007;74:72-84.
    • (2007) Microvasc Res , vol.74 , pp. 72-84
    • Fukumura, D.1    Jain, R.K.2
  • 57
    • 0032912142 scopus 로고    scopus 로고
    • Pathophysiology of the thrombophilic state in the cancer patient
    • Falanga A, Rickles FR. Pathophysiology of the thrombophilic state in the cancer patient. Semin Thromb Hemost 1999;25:173-82.
    • (1999) Semin Thromb Hemost , vol.25 , pp. 173-182
    • Falanga, A.1    Rickles, F.R.2
  • 58
    • 0035876016 scopus 로고    scopus 로고
    • Molecular basis for the relationship between thrombosis and cancer
    • Rickles FR, Falanga A. Molecular basis for the relationship between thrombosis and cancer. Thromb Res 2001;102:V215-24.
    • (2001) Thromb Res , vol.102
    • Rickles, F.R.1    Falanga, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.