The CSL transcription factor LAG-1 directly represses hlh-6 expression in C. elegans

Developmental Biology

Volumn 322, Issue 2, 2008, Pages 334-344

  Ghai, Vikas ^a   Gaudet, Jeb ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

bHLH; C. elegans; Gene regulation; Glands; Notch; Pharynx

Indexed keywords

NOTCH RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR LAG 1; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BINDING SITE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; GENE ACTIVITY; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE REPRESSION; GENE TARGETING; HLH 6 GENE; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL;

CAENORHABDITIS ELEGANS;

EID: 53049085365     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2008.07.018     Document Type: Article

References (52)

1. Aamodt E.J., Chung M.A., and McGhee J.D. Spatial control of gut-specific gene expression during Caenorhabditis elegans development. Science 252 (1991) 579-582
2. Albertson D.G., and Thomson J.N. The pharynx of Caenorhabditis elegans. Philos. Trans. R. Soc. Lond. B Biol. Sci. 275 (1976) 299-325
3. Austin J., and Kimble J. Transcript analysis of glp-1 and lin-12 homologous genes required for cell interactions during development of C. elegans. Cell 58 (1989) 565-571
4. Barolo S., Walker R.G., Polyanovsky A.D., Freschi G., Keil T., and Posakony J.W. A notch-independent activity of suppressor of hairless is required for normal mechanoreceptor physiology. Cell 103 (2000) 957-969
5. Bray S.J. Notch signalling: a simple pathway becomes complex. Nat. Rev. Mol. Cell. Biol. 7 (2006) 678-689
6. Brenner S. The genetics of Caenorhabditis elegans. Genetics 77 (1974) 71-94
7. Brou C., Logeat F., Lecourtois M., Vanderkerckhove J., Kourilsky P., Schweisguth F., and Israel A. Inhibition of the DNA-binding activity of Drosophila suppressor of hairless and of its human homolog, KBF2/RBP-Jk, by direct protein-protein interaction with Drosophila Hairless. Genes & Development 8 (1994) 2491-2503
8. Campbell R.E., Tour O., Palmer A.E., Steinbach P.A., Baird G.S., Zacharias D.A., and Tsien R.Y. A monomeric red fluorescent protein. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 7877-7882
9. Cave J.W., Loh F., Surpris J.W., Xia L., and Caudy M.A. A DNA transcription code for cell-specific gene activation by notch signaling. Curr. Biol. 15 (2005) 94-104
10. Christensen S., Kodoyianni V., Bosenberg M., Friedman L., and Kimble J. lag-1, a gene required for lin-12 and glp-1 signaling in Caenorhabditis elegans, is homologous to human CBF1 and Drosophila Su(H). Development 122 (1996) 1373-1383
11. Dieterich C., and Sommer R.J. A Caenorhabditis motif compendium for studying transcriptional gene regulation. BMC Genomics 9 (2008) 30
12. Fukushige T., Hawkins M.G., and McGhee J.D. The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine. Dev. Biol. 198 (1998) 286-302
13. Gaudet J., and Mango S.E. Regulation of organogenesis by the Caenorhabditis elegans FoxA protein PHA-4. Science 295 (2002) 821-825
14. Greenwald I. LIN-12/Notch signaling in C. elegans. WormBook (2005) 1-16
15. Greenwald I.S., Sternberg P.W., and Horvitz H.R. The lin-12 locus specifies cell fates in C. elegans. Cell 34 (1983) 435-444
16. Gupta B.P., and Sternberg P.W. Tissue-specific regulation of the LIM homeobox gene lin-11 during development of the Caenorhabditis elegans egg-laying system. Dev. Biol. 247 (2002) 102-115
17. Guss K.A., Nelson C.E., Hudson A., Kraus M.E., and Carroll S.B. Control of a genetic regulatory network by a selector gene. Science 292 (2001) 1164-1167
18. Haberman A.S., Isaac D.D., and Andrew D.J. Specification of cell fates within the salivary gland primordium. Dev. Biol. 258 (2003) 443-453
19. Ho S.N., Hunt H.D., Horton R.M., Pullen J.K., and Pease L.R. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77 (1989) 51-59
20. Horner M.A., Quintin S., Domeier M.E., Kimble J., Labouesse M., and Mango S.E. pha-4, an HNF-3 homologue, specifies pharyngeal organ identity in Caenorhabditis elegans. Genes Dev. 12 (1998) 1947-1952
21. Ito M., Katada T., Miyatani S., and Kinoshita T. XSu(H)2 is an essential factor for gene expression and morphogenesis of the Xenopus gastrula embryo. Int. J. Dev. Biol. 51 (2007) 27-36
22. Kalb J.M., Lau K.K., Goszczynski B., Fukushige T., Moons D., Okkema P.G., and McGhee J.D. pha-4 is Ce-fkh-1, a fork head/HNF-3alpha,beta,gamma homolog that functions in organogenesis of the C. elegans pharynx. Development 125 (1998) 2171-2180
23. Kalb J.M., Beaster-Jones L., Fernandez A.P., Okkema P.G., Goszczynski B., and McGhee J.D. Interference between the PHA-4 and PEB-1 transcription factors in formation of the Caenorhabditis elegans pharynx. J. Mol. Biol. 320 (2002) 697-704
24. Klein T., Seugnet L., Haenlin M., and Martinez Arias A. Two different activities of Suppressor of Hairless during wing development in Drosophila. Development 127 (2000) 3553-3566
25. Koelzer S., and Klein T. A Notch-independent function of suppressor of hairless during the development of the bristle sensory organ precursor cell of Drosophila. Development 130 (2003) 1973-1988
26. Kovall R.A., and Hendrickson W.A. Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA. EMBO J. 23 (2004) 3441-3451
27. Lambie E.J., and Kimble J. Two homologous regulatory genes, lin-12 and glp-1, have overlapping functions. Development 112 (1991) 231-240
28. Mango S.E., Maine E.M., and Kimble J. Carboxy-terminal truncation activates glp-1 protein to specify vulval fates in Caenorhabditis elegans. Nature 352 (1991) 811-815
29. Masui T., Long Q., Beres T.M., Magnuson M.A., and MacDonald R.J. Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex. Genes Dev. 21 (2007) 2629-2643
30. Mello C.C., Kramer J.M., Stinchcomb D., and Ambros V. Efficient gene transfer in C. elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J. 10 (1991) 3959-3970
31. Morck C., Rauthan M., Wagberg F., and Pilon M. pha-2 encodes the C. elegans ortholog of the homeodomain protein HEX and is required for the formation of the pharyngeal isthmus. Dev. Biol. 272 (2004) 403-418
32. Neves A., English K., and Priess J.R. Notch-GATA synergy promotes endoderm-specific expression of ref-1 in C. elegans. Development 134 (2007) 4459-4468
33. Okkema P.G., and Fire A. The Caenorhabditis elegans NK-2 class homeoprotein CEH-22 is involved in combinatorial activation of gene expression in pharyngeal muscle. Development 120 (1994) 2175-2186
34. Okkema P.G., and Krause M. Transcriptional regulation. WormBook (2005) 1-40
35. Okkema P.G., Ha E., Haun C., Chen W., and Fire A. The Caenorhabditis elegans NK-2 homeobox gene ceh-22 activates pharyngeal muscle gene expression in combination with pha-1 and is required for normal pharyngeal development. Development 124 (1997) 3965-3973
36. Overdier D.G., Porcella A., and Costa R.H. The DNA-binding specificity of the hepatocyte nuclear factor 3/forkhead domain is influenced by amino acid residues adjacent to the recognition helix. Molecular and Cellular Biology 14 (1994) 2755-2766
37. Priess J.R. Notch signaling in the C. elegans embryo. WormBook (2005) 1-16
38. Raharjo I., and Gaudet J. Gland-specific expression of C. elegans hlh-6 requires the combinatorial action of three distinct promoter elements. Dev. Biol. 302 (2007) 295-308
39. Roehl H., and Kimble J. Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats. Nature 364 (1993) 632-635
40. Roy Chowdhuri S., Crum T., Woollard A., Aslam S., and Okkema P.G. The T-box factor TBX-2 and the SUMO conjugating enzyme UBC-9 are required for ABa-derived pharyngeal muscle in C. elegans. Dev. Biol. 295 (2006) 664-677
41. Schnabel H., and Schnabel R. An organ-specific differentiation gene, pha-1, from Caenorhabditis elegans. Science 250 (1990) 686-688
42. Schug J. Using TESS to predict transcription factor binding sites in DNA sequence. In: Baxevanis A.D. (Ed). "Current Protocols in Bioinformatics" (2003), J. Wiley and Sons
43. Smit, R.B., and Gaudet, J., (in preparation). HLH-6 Regulates C. elegans Pharyngeal Gland Development and Function.
44. Smith P.A., and Mango S.E. Role of T-box gene tbx-2 for anterior foregut muscle development in C. elegans. Dev. Biol. (2006)
45. Sulston J.E., Schierenberg E., White J.G., and Thomson J.N. The embryonic cell lineage of the nematode Caenorhabditis elegans. Devel. Biol. 100 (1983) 64-119
46. Takiya S., Gazi M., and Mach V. The DNA binding of insect Fork head factors is strongly influenced by the negative cooperation of neighbouring bases. Insect Biochem Mol Biol 33 (2003) 1145-1154
47. Thatcher J.D., Fernandez A.P., Beaster-Jones L., Haun C., and Okkema P.G. The Caenorhabditis elegans peb-1 gene encodes a novel DNA-binding protein involved in morphogenesis of the pharynx, vulva, and hindgut. Dev. Biol. 229 (2001) 480-493
48. Tun T., Hamaguchi Y., Matsunami N., Furukawa T., Honjo T., and Kawaichi M. Recognition sequence of a highly conserved DNA binding protein RBP-Jκ. Nucleic Acids Research 22 (1994) 965-971
49. Tyagi M., and Karn J. CBF-1 promotes transcriptional silencing during the establishment of HIV-1 latency. EMBO J. 26 (2007) 4985-4995
50. Yochem J., and Greenwald I. glp-1 and lin-12, genes implicated in distinct cell-cell interactions in C. elegans, encode similar transmembrane proteins. Cell 58 (1989) 553-563
51. Yochem J., Weston K., and Greenwald I. The Caenorhabditis elegans lin-12 gene encodes a transmembrane protein with overall similarity to Drosophila Notch. Nature 335 (1988) 547-550
52. Yoo A.S., Bais C., and Greenwald I. Crosstalk between the EGFR and LIN-12/Notch pathways in C. elegans vulval development. Science 303 (2004) 663-666