메뉴 건너뛰기




Volumn 20, Issue 10, 2008, Pages 1299-1311

Altered cellular immunity in transgenic mice with T cell-specific expression of human D4-guanine diphosphate-dissociation inhibitor (D4-GDI)

Author keywords

Cytoskeletal organization; Cytozoic pathogens; Leukemic cells; Proliferation; Rho

Indexed keywords

BCG VACCINE; CD3 ANTIGEN; CONCANAVALIN A; GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR; PROTEIN KINASE LCK;

EID: 52949124867     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxn084     Document Type: Article
Times cited : (3)

References (42)
  • 1
    • 33748994545 scopus 로고    scopus 로고
    • Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking
    • Ridley, A. J. 2006. Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. Trends Cell Biol. 16:522.
    • (2006) Trends Cell Biol , vol.16 , pp. 522
    • Ridley, A.J.1
  • 2
    • 0034009104 scopus 로고    scopus 로고
    • Augmentation of human leukemia cell invasion by the activation of small GTP-binding protein Rho
    • Fukushima, S., Yamada, T., Hashiguchi, A., Nakata, Y. and Hata, J. 2000. Augmentation of human leukemia cell invasion by the activation of small GTP-binding protein Rho. Exp. Hematol. 28:391.
    • (2000) Exp. Hematol , vol.28 , pp. 391
    • Fukushima, S.1    Yamada, T.2    Hashiguchi, A.3    Nakata, Y.4    Hata, J.5
  • 4
    • 0029791373 scopus 로고    scopus 로고
    • The small GTPase Rho: Cellular functions and signal transduction
    • Narumiya, S. 1996. The small GTPase Rho: Cellular functions and signal transduction. J. Biochem. 120:215.
    • (1996) J. Biochem , vol.120 , pp. 215
    • Narumiya, S.1
  • 5
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall, A. 1998, Rho GTPases and the actin cytoskeleton. Science 279:509.
    • (1998) Science , vol.279 , pp. 509
    • Hall, A.1
  • 6
    • 0029145073 scopus 로고
    • Rho family members: Activators of MAP kinase cascades
    • Vojtek, A. B. and Cooper, J. A. 1995. Rho family members: Activators of MAP kinase cascades. Cell 82:527.
    • (1995) Cell , vol.82 , pp. 527
    • Vojtek, A.B.1    Cooper, J.A.2
  • 7
    • 0030968580 scopus 로고    scopus 로고
    • Rho GTPases and signaling networks
    • Van Aelst, L. and D'Souza-Schorey, C. 1997. Rho GTPases and signaling networks. Genes Dev. 11:2295.
    • (1997) Genes Dev , vol.11 , pp. 2295
    • Van Aelst, L.1    D'Souza-Schorey, C.2
  • 8
    • 0027526303 scopus 로고
    • cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteins
    • Lelias, J. M., Adra, C. N., Wulf, G. M. et al. 1993. cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteins. Proc. Natl Acad. Sci. USA 90:1479.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 1479
    • Lelias, J.M.1    Adra, C.N.2    Wulf, G.M.3
  • 9
    • 0027237511 scopus 로고
    • Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes
    • Scherle, P., Behrens, T. and Staudt, L. M. 1993. Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes. Proc. Natl Acad. Sci. USA 90:7568.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 7568
    • Scherle, P.1    Behrens, T.2    Staudt, L.M.3
  • 10
    • 0030611196 scopus 로고    scopus 로고
    • Rho-GDlγ: A GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas
    • Adra, C. N., Manor, D., Ko, J. L. et al. 1997. Rho-GDlγ: A GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas. Proc. Natl Acad. Sci. USA 94:4279.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 4279
    • Adra, C.N.1    Manor, D.2    Ko, J.L.3
  • 11
    • 21744432683 scopus 로고    scopus 로고
    • GDIs: Central regulatory molecules in Rho GTPase activation
    • DerMardirossian, C. and Bokoch, G. M. 2005. GDIs: Central regulatory molecules in Rho GTPase activation. Trends Cell Biol. 15:356.
    • (2005) Trends Cell Biol , vol.15 , pp. 356
    • DerMardirossian, C.1    Bokoch, G.M.2
  • 12
    • 0026496258 scopus 로고
    • A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs
    • Hart, M. J., Maru, Y., Leonard, D. et al. 1992. A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs. Science 258:812.
    • (1992) Science , vol.258 , pp. 812
    • Hart, M.J.1    Maru, Y.2    Leonard, D.3
  • 13
    • 0027393663 scopus 로고
    • GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein
    • Chuang, T H., Xu, X., Knaus, U. G., Hart, M. J. and Bokoch, G. M. 1993. GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein. J. Biol. Chem. 268:775.
    • (1993) J. Biol. Chem , vol.268 , pp. 775
    • Chuang, T.H.1    Xu, X.2    Knaus, U.G.3    Hart, M.J.4    Bokoch, G.M.5
  • 14
    • 0030846295 scopus 로고    scopus 로고
    • Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/ moesin initiates the activation of the Rho small G protein
    • Takahashi, K., Sasaki, T., Mamoto, A. et al. 1997. Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/ moesin initiates the activation of the Rho small G protein. J. Biol. Chem. 272:23371.
    • (1997) J. Biol. Chem , vol.272 , pp. 23371
    • Takahashi, K.1    Sasaki, T.2    Mamoto, A.3
  • 15
    • 0032579315 scopus 로고    scopus 로고
    • Differential properties of D4/LyGDI versus RhoGDI: Phosphorylation and rho GTPase selectivity
    • Gorvel, J. P., Chang, T.-C., Boretto, J., Azuma, T. and Chavrier, P. 1998. Differential properties of D4/LyGDI versus RhoGDI: Phosphorylation and rho GTPase selectivity. FEBS Lett. 422:263.
    • (1998) FEBS Lett , vol.422 , pp. 263
    • Gorvel, J.P.1    Chang, T.-C.2    Boretto, J.3    Azuma, T.4    Chavrier, P.5
  • 16
    • 0034194059 scopus 로고    scopus 로고
    • Differential expression and regulation of GTPases (RhoA and Rac2) and GDIs (LyGDI and RhoGDI) in neutrophils from patients with severe congenital neutropenia
    • Kasper, B., Tidow, N., Grothues, D. and Welte, K. 2000. Differential expression and regulation of GTPases (RhoA and Rac2) and GDIs (LyGDI and RhoGDI) in neutrophils from patients with severe congenital neutropenia. Blood 95:2947.
    • (2000) Blood , vol.95 , pp. 2947
    • Kasper, B.1    Tidow, N.2    Grothues, D.3    Welte, K.4
  • 17
    • 0033956628 scopus 로고    scopus 로고
    • Vav, a GDP/GTP nucleotide exchange factor, interacts with GDIs, proteins that inhibit GDP/GTP dissociation
    • Groysman, M., Russek, C. S. and Katzav, S. 2000. Vav, a GDP/GTP nucleotide exchange factor, interacts with GDIs, proteins that inhibit GDP/GTP dissociation. FEBS Lett. 467:75.
    • (2000) FEBS Lett , vol.467 , pp. 75
    • Groysman, M.1    Russek, C.S.2    Katzav, S.3
  • 18
    • 0037147241 scopus 로고    scopus 로고
    • Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathways
    • Groysman, M., Hornstein, I., Alcover, A. and Katzav, S. 2002. Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathways. J. Biol. Chem. 277:50121.
    • (2002) J. Biol. Chem , vol.277 , pp. 50121
    • Groysman, M.1    Hornstein, I.2    Alcover, A.3    Katzav, S.4
  • 19
    • 15844409177 scopus 로고    scopus 로고
    • D4-GDI, a substrate of CPP32, is proteolyzed during Fas-induced apoptosis
    • Na, S., Chuang, T. H., Cunningham, A. et al. 1996. D4-GDI, a substrate of CPP32, is proteolyzed during Fas-induced apoptosis. J. Biol. Chem. 271:11209.
    • (1996) J. Biol. Chem , vol.271 , pp. 11209
    • Na, S.1    Chuang, T.H.2    Cunningham, A.3
  • 20
    • 0032991861 scopus 로고    scopus 로고
    • Cleavage and nuclear translocation of the caspase 3 substrate Rho GDP-dissociation inhibitor, D4-GDI, during apoptosis
    • Krieser, R. J. and Eastman, A. 1999. Cleavage and nuclear translocation of the caspase 3 substrate Rho GDP-dissociation inhibitor, D4-GDI, during apoptosis. Cell Death Differ. 6:412.
    • (1999) Cell Death Differ , vol.6 , pp. 412
    • Krieser, R.J.1    Eastman, A.2
  • 21
    • 37249002893 scopus 로고    scopus 로고
    • Mutated D4-guanine diphosphate-dissociation inhibitor is found in human leukemic cells and promotes leukemic cell invasion
    • Nakata, Y., Kondoh, K., Fukushima, S. et al. 2008. Mutated D4-guanine diphosphate-dissociation inhibitor is found in human leukemic cells and promotes leukemic cell invasion. Exp. Hematol. 36:37.
    • (2008) Exp. Hematol , vol.36 , pp. 37
    • Nakata, Y.1    Kondoh, K.2    Fukushima, S.3
  • 22
    • 0017702412 scopus 로고
    • Characterization of EBV-genome negative null and T cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma
    • Schneider, U., Schwenk, H. U. and Bornkamm, G. 1977. Characterization of EBV-genome negative null and T cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma. Int. J. Cancer 19:521.
    • (1977) Int. J. Cancer , vol.19 , pp. 521
    • Schneider, U.1    Schwenk, H.U.2    Bornkamm, G.3
  • 25
    • 0033081753 scopus 로고    scopus 로고
    • Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
    • Ren, X. D., Kiosses, W. B. and Schwartz, M. A. 1999. Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO. J. 18:578.
    • (1999) EMBO. J , vol.18 , pp. 578
    • Ren, X.D.1    Kiosses, W.B.2    Schwartz, M.A.3
  • 26
    • 0029889591 scopus 로고    scopus 로고
    • Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain
    • Reid, T., Furuyashiki, T., Ishizaki, T. et al. 1996. Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain. J. Biol. Chem. 271:13556.
    • (1996) J. Biol. Chem , vol.271 , pp. 13556
    • Reid, T.1    Furuyashiki, T.2    Ishizaki, T.3
  • 27
    • 0026017971 scopus 로고
    • Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis
    • Lenardo, M. J. 1991. Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis. Nature 353:858.
    • (1991) Nature , vol.353 , pp. 858
    • Lenardo, M.J.1
  • 28
    • 0032712574 scopus 로고    scopus 로고
    • Fluorescent dyes for lymphocyte migration and proliferation studies
    • Parish, C. R. 1999. Fluorescent dyes for lymphocyte migration and proliferation studies. Immunol. Cell Biol. 77:499.
    • (1999) Immunol. Cell Biol , vol.77 , pp. 499
    • Parish, C.R.1
  • 29
    • 0030869004 scopus 로고    scopus 로고
    • Immune responses in mice deficient in Ly-GDI, a lymphoid-specific regulator of Rho GTPases
    • Yin, L., Schwartzberg, P., Scharton-Kersten, T. M., Staudt, L. and Lenardo, M. 1997. Immune responses in mice deficient in Ly-GDI, a lymphoid-specific regulator of Rho GTPases. Mol. Immunol. 34:481.
    • (1997) Mol. Immunol , vol.34 , pp. 481
    • Yin, L.1    Schwartzberg, P.2    Scharton-Kersten, T.M.3    Staudt, L.4    Lenardo, M.5
  • 30
    • 33845439460 scopus 로고    scopus 로고
    • Defective chemokine-directed lymphocyte migration and development in the absence of Rho guanosine diphosphate-dissociation inhibitors alpha and beta
    • Ishizaki, H., Togawa, A., Tanaka-Okamoto, M. et al. 2006. Defective chemokine-directed lymphocyte migration and development in the absence of Rho guanosine diphosphate-dissociation inhibitors alpha and beta. J. Immunol. 177:8512.
    • (2006) J. Immunol , vol.177 , pp. 8512
    • Ishizaki, H.1    Togawa, A.2    Tanaka-Okamoto, M.3
  • 31
    • 0030992879 scopus 로고    scopus 로고
    • C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases
    • Gosser, Y. Q., Nomanbhoy, T. K., Aghazadeh, B. et al. 1997. C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases. Nature 387:814.
    • (1997) Nature , vol.387 , pp. 814
    • Gosser, Y.Q.1    Nomanbhoy, T.K.2    Aghazadeh, B.3
  • 32
    • 0023718983 scopus 로고
    • Secondary structure prediction: Combination of three different methods
    • Biou, V., Gibrat, J. F., Levin, J. M., Robson, B. and Garnier, J. 1988. Secondary structure prediction: Combination of three different methods. Protein Eng. 2:185.
    • (1988) Protein Eng , vol.2 , pp. 185
    • Biou, V.1    Gibrat, J.F.2    Levin, J.M.3    Robson, B.4    Garnier, J.5
  • 33
    • 15844409177 scopus 로고    scopus 로고
    • D4-GDI, a substrate of CPP32, is proteolyzed during Fas-induced apoptosis
    • Na, S., Chuang, T. H., Cunningham, A. et al. 1996. D4-GDI, a substrate of CPP32, is proteolyzed during Fas-induced apoptosis. J Biol. Chem. 271:11209.
    • (1996) J Biol. Chem , vol.271 , pp. 11209
    • Na, S.1    Chuang, T.H.2    Cunningham, A.3
  • 34
    • 0029951250 scopus 로고    scopus 로고
    • Defective Rho GTPase regulation by IL-1 beta-converting enzyme-mediated cleavage of D4 GDP dissociation inhibitor
    • Danley, D. E., Chuang, T. H. and Bokoch, G. M. 1996. Defective Rho GTPase regulation by IL-1 beta-converting enzyme-mediated cleavage of D4 GDP dissociation inhibitor. J. Immunol. 157:500.
    • (1996) J. Immunol , vol.157 , pp. 500
    • Danley, D.E.1    Chuang, T.H.2    Bokoch, G.M.3
  • 35
    • 0031985337 scopus 로고    scopus 로고
    • Inhibition of CPP32 blocks surface. IgM-mediated apoptosis and D4-GDI cleavage in human BL60 Burkitt lymphoma cells
    • Rickers, A., Brockstedt, E., Mapara, M. Y. et al. 1998. Inhibition of CPP32 blocks surface. IgM-mediated apoptosis and D4-GDI cleavage in human BL60 Burkitt lymphoma cells. Eur. J. Immunol. 28:296.
    • (1998) Eur. J. Immunol , vol.28 , pp. 296
    • Rickers, A.1    Brockstedt, E.2    Mapara, M.Y.3
  • 36
    • 33745233810 scopus 로고    scopus 로고
    • D4-GDI, a Rho GTPase regulator, promotes breast cancer cell invasiveness
    • Zhang, Y. and Zhang, B. 2006. D4-GDI, a Rho GTPase regulator, promotes breast cancer cell invasiveness. Cancer Res. 66:5592.
    • (2006) Cancer Res , vol.66 , pp. 5592
    • Zhang, Y.1    Zhang, B.2
  • 37
    • 0041631013 scopus 로고    scopus 로고
    • Caspase 3-mediated inactivation of rac GTPases promotes drug-induced apoptosis in human lymphoma cells
    • Zhang, B., Zhang, Y. and Shacter, E. 2003. Caspase 3-mediated inactivation of rac GTPases promotes drug-induced apoptosis in human lymphoma cells. Mol. Cell Biol. 23:5716.
    • (2003) Mol. Cell Biol , vol.23 , pp. 5716
    • Zhang, B.1    Zhang, Y.2    Shacter, E.3
  • 38
    • 3042800912 scopus 로고    scopus 로고
    • Rac1 inhibits apoptosis in human lymphoma cells by stimulating Bad phosphorylation on Ser-75
    • Zhang, B., Zhang, Y. and Shacter, E. 2004. Rac1 inhibits apoptosis in human lymphoma cells by stimulating Bad phosphorylation on Ser-75. Mol. Cell Biol. 24:6205.
    • (2004) Mol. Cell Biol , vol.24 , pp. 6205
    • Zhang, B.1    Zhang, Y.2    Shacter, E.3
  • 39
    • 22244467726 scopus 로고    scopus 로고
    • Rho GDP dissociation inhibitor protects cancer cells against drug-induced apoptosis
    • Zhang, B., Zhang, Y., Dagher, M. C. et al. 2005. Rho GDP dissociation inhibitor protects cancer cells against drug-induced apoptosis. Cancer Res. 65:6054.
    • (2005) Cancer Res , vol.65 , pp. 6054
    • Zhang, B.1    Zhang, Y.2    Dagher, M.C.3
  • 40
    • 0033851311 scopus 로고    scopus 로고
    • TNF-[alpha]-mediated neutrophil apoptosis involves Ly-GDI, a Rho GTPase regulator
    • Kettritz, R., Xu, T. X., Faass, B. et al. 2000. TNF-[alpha]-mediated neutrophil apoptosis involves Ly-GDI, a Rho GTPase regulator. J. Leukoc. Biol. 68:277.
    • (2000) J. Leukoc. Biol , vol.68 , pp. 277
    • Kettritz, R.1    Xu, T.X.2    Faass, B.3
  • 41
    • 0029795488 scopus 로고    scopus 로고
    • Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: Possible involvement of phosphatidylinositol turn-over and Rho-dependent signaling pathway
    • Hirao, M., Sato, N., Kondo, T. et al. 1996. Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turn-over and Rho-dependent signaling pathway. J. Cell Biol. 135:37.
    • (1996) J. Cell Biol , vol.135 , pp. 37
    • Hirao, M.1    Sato, N.2    Kondo, T.3
  • 42
    • 0036150120 scopus 로고    scopus 로고
    • The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function
    • Li, X., Bu, X., Lu, B., Avraham, H., Flavell, R. A. and Lim, B. 2002. The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function. Mol. Cell Biol. 22:1158.
    • (2002) Mol. Cell Biol , vol.22 , pp. 1158
    • Li, X.1    Bu, X.2    Lu, B.3    Avraham, H.4    Flavell, R.A.5    Lim, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.