메뉴 건너뛰기




Volumn 36, Issue 1, 2008, Pages 37-50

Mutated D4-guanine diphosphate-dissociation inhibitor is found in human leukemic cells and promotes leukemic cell invasion

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; D4 GUANINE DIPHOSPHATE DISSOCIATION INHIBITOR; GENE PRODUCT; GUANINE TRIPHOSPHATE; PROTEIN CDC42; RAC PROTEIN; RHO FACTOR; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

EID: 37249002893     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2007.08.023     Document Type: Article
Times cited : (6)

References (52)
  • 1
    • 0034009104 scopus 로고    scopus 로고
    • Augmentation of human leukemia cell invasion by the activation of small GTP-binding protein Rho
    • Fukushima S., Yamada T., Hashiguchi A., Nakata Y., and Hata J. Augmentation of human leukemia cell invasion by the activation of small GTP-binding protein Rho. Exp Hematol 28 (2000) 391-400
    • (2000) Exp Hematol , vol.28 , pp. 391-400
    • Fukushima, S.1    Yamada, T.2    Hashiguchi, A.3    Nakata, Y.4    Hata, J.5
  • 2
    • 0028170820 scopus 로고
    • Small GTP-binding proteins and the regulation of the actin cytoskeleton
    • Hall A. Small GTP-binding proteins and the regulation of the actin cytoskeleton. Annu Rev Cell Biol 10 (1994) 31-54
    • (1994) Annu Rev Cell Biol , vol.10 , pp. 31-54
    • Hall, A.1
  • 4
    • 0029791373 scopus 로고    scopus 로고
    • The small GTPase Rho: cellular functions and signal transduction
    • Narumiya S. The small GTPase Rho: cellular functions and signal transduction. J Biochem 120 (1996) 215-228
    • (1996) J Biochem , vol.120 , pp. 215-228
    • Narumiya, S.1
  • 5
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall A. Rho GTPases and the actin cytoskeleton. Science 279 (1998) 509-514
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 6
    • 0029145073 scopus 로고
    • Rho family members: activators of MAP kinase cascades
    • Vojtek A.B., and Cooper J.A. Rho family members: activators of MAP kinase cascades. Cell 82 (1995) 527-529
    • (1995) Cell , vol.82 , pp. 527-529
    • Vojtek, A.B.1    Cooper, J.A.2
  • 7
    • 0030968580 scopus 로고    scopus 로고
    • Rho GTPases and signaling networks
    • Van Aelst L., and D'Souza-Schorey C. Rho GTPases and signaling networks. Genes Dev 11 (1997) 2295-2322
    • (1997) Genes Dev , vol.11 , pp. 2295-2322
    • Van Aelst, L.1    D'Souza-Schorey, C.2
  • 8
    • 0027526303 scopus 로고
    • cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteins
    • Lelias J.M., Adra C.N., Wulf G.M., et al. cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteins. Proc Natl Acad Sci U S A 90 (1993) 1479-1483
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 1479-1483
    • Lelias, J.M.1    Adra, C.N.2    Wulf, G.M.3
  • 9
    • 0027237511 scopus 로고
    • Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes
    • Scherle P., Behrens T., and Staudt L.M. Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes. Proc Natl Acad Sci U S A 90 (1993) 7568-7572
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 7568-7572
    • Scherle, P.1    Behrens, T.2    Staudt, L.M.3
  • 10
    • 0030611196 scopus 로고    scopus 로고
    • Rho-GDIγ: a GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas
    • Adra C.N., Manor D., Ko J.L., et al. Rho-GDIγ: a GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas. Proc Natl Acad Sci U S A 94 (1997) 4279-4284
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 4279-4284
    • Adra, C.N.1    Manor, D.2    Ko, J.L.3
  • 11
    • 21744432683 scopus 로고    scopus 로고
    • GDIs: central regulatory molecules in Rho GTPase activation
    • DerMardirossian C., and Bokoch G.M. GDIs: central regulatory molecules in Rho GTPase activation. Trends Cell Biol 15 (2005) 356-363
    • (2005) Trends Cell Biol , vol.15 , pp. 356-363
    • DerMardirossian, C.1    Bokoch, G.M.2
  • 12
    • 0026496258 scopus 로고
    • A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs
    • Hart M.J., Maru Y., Leonard D., Witte O.N., Evans T., and Cerione R.A. A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs. Science 258 (1992) 812-815
    • (1992) Science , vol.258 , pp. 812-815
    • Hart, M.J.1    Maru, Y.2    Leonard, D.3    Witte, O.N.4    Evans, T.5    Cerione, R.A.6
  • 13
    • 0027393663 scopus 로고
    • GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein
    • Chuang T.H., Xu X., Knaus U.G., Hart M.J., and Bokoch G.M. GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein. J Biol Chem 268 (1993) 775-778
    • (1993) J Biol Chem , vol.268 , pp. 775-778
    • Chuang, T.H.1    Xu, X.2    Knaus, U.G.3    Hart, M.J.4    Bokoch, G.M.5
  • 14
    • 0030846295 scopus 로고    scopus 로고
    • Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein
    • 23371-22375
    • Takahashi K., Sasaki T., Mammoto A., et al. Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein. J Biol Chem 272 (1997) 23371-22375
    • (1997) J Biol Chem , vol.272
    • Takahashi, K.1    Sasaki, T.2    Mammoto, A.3
  • 15
    • 0032579315 scopus 로고    scopus 로고
    • Differential properties of D4/LyGDI versus RhoGDI: phosphorylation and rho GTPase selectivity
    • Gorvel J.P., Chang T.C., Boretto J., et al. Differential properties of D4/LyGDI versus RhoGDI: phosphorylation and rho GTPase selectivity. FEBS Lett 422 (1998) 269-273
    • (1998) FEBS Lett , vol.422 , pp. 269-273
    • Gorvel, J.P.1    Chang, T.C.2    Boretto, J.3
  • 16
    • 0035808306 scopus 로고    scopus 로고
    • Structure-activity relationships in flexible protein domains: regulation of rho GTPases by RhoGDI and D4 GDI
    • Golovanov A.P., Chuang T.H., DerMardirossian C., et al. Structure-activity relationships in flexible protein domains: regulation of rho GTPases by RhoGDI and D4 GDI. J Mol Biol 305 (2001) 121-135
    • (2001) J Mol Biol , vol.305 , pp. 121-135
    • Golovanov, A.P.1    Chuang, T.H.2    DerMardirossian, C.3
  • 17
    • 15844409177 scopus 로고    scopus 로고
    • D4-GDI, a substrate of CPP32, is proteolyzed during Fas-induced apoptosis
    • Na S., Chuang T.H., Cunningham A., et al. D4-GDI, a substrate of CPP32, is proteolyzed during Fas-induced apoptosis. J Biol Chem 271 (1996) 11209-11213
    • (1996) J Biol Chem , vol.271 , pp. 11209-11213
    • Na, S.1    Chuang, T.H.2    Cunningham, A.3
  • 18
    • 0032991861 scopus 로고    scopus 로고
    • Cleavage and nuclear translocation of the caspase 3 substrate Rho GDP-dissociation inhibitor, D4-GDI, during apoptosis
    • Krieser R.J., and Eastman A. Cleavage and nuclear translocation of the caspase 3 substrate Rho GDP-dissociation inhibitor, D4-GDI, during apoptosis. Cell Death Differ 6 (1999) 412-419
    • (1999) Cell Death Differ , vol.6 , pp. 412-419
    • Krieser, R.J.1    Eastman, A.2
  • 19
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: a review
    • Bos J.L. Ras oncogenes in human cancer: a review. Cancer Res 49 (1989) 4682-4689
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 20
    • 0028107143 scopus 로고
    • Examination of human tumors for rhoA mutations
    • Moscow J.A., He R., Gnarra J.R., et al. Examination of human tumors for rhoA mutations. Oncogene 9 (1994) 189-194
    • (1994) Oncogene , vol.9 , pp. 189-194
    • Moscow, J.A.1    He, R.2    Gnarra, J.R.3
  • 21
    • 0030455117 scopus 로고    scopus 로고
    • Regulation of cytoskeletal functions by Rho small GTP-binding proteins in normal and cancer cells
    • Boivin D., Bilodeau D., and Beliveau R. Regulation of cytoskeletal functions by Rho small GTP-binding proteins in normal and cancer cells. Can J Physiol Pharmacol 74 (1996) 801-810
    • (1996) Can J Physiol Pharmacol , vol.74 , pp. 801-810
    • Boivin, D.1    Bilodeau, D.2    Beliveau, R.3
  • 22
    • 0031033292 scopus 로고    scopus 로고
    • Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product
    • Crespo P., Schuebel K.E., Ostrom A.A., Gutkind J.S., and Bustelo X.R. Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product. Nature 385 (1997) 169-172
    • (1997) Nature , vol.385 , pp. 169-172
    • Crespo, P.1    Schuebel, K.E.2    Ostrom, A.A.3    Gutkind, J.S.4    Bustelo, X.R.5
  • 23
    • 0021825489 scopus 로고
    • Isolation of a new human oncogene from a diffuse B-cell lymphoma
    • Eva A., and Aaronson S.A. Isolation of a new human oncogene from a diffuse B-cell lymphoma. Nature 316 (1985) 273-275
    • (1985) Nature , vol.316 , pp. 273-275
    • Eva, A.1    Aaronson, S.A.2
  • 24
    • 0028225439 scopus 로고
    • Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins
    • Habets G.G., Scholtes E.H., Zuydgeest D., et al. Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins. Cell 77 (1994) 537-549
    • (1994) Cell , vol.77 , pp. 537-549
    • Habets, G.G.1    Scholtes, E.H.2    Zuydgeest, D.3
  • 25
    • 1542328238 scopus 로고    scopus 로고
    • Rho GTPases: potential candidates for anticancer therapy
    • Aznar S., Fernandez-Valeron P., Espina C., et al. Rho GTPases: potential candidates for anticancer therapy. Cancer Lett 206 (2004) 181-191
    • (2004) Cancer Lett , vol.206 , pp. 181-191
    • Aznar, S.1    Fernandez-Valeron, P.2    Espina, C.3
  • 26
    • 0034719380 scopus 로고    scopus 로고
    • Motility and invasion are differentially modulated by Rho family GTPases
    • Banyard J., Anand-Apte B., Symons M., et al. Motility and invasion are differentially modulated by Rho family GTPases. Oncogene 19 (2000) 580-591
    • (2000) Oncogene , vol.19 , pp. 580-591
    • Banyard, J.1    Anand-Apte, B.2    Symons, M.3
  • 27
    • 0036191304 scopus 로고    scopus 로고
    • Rho GTPases in transformation and metastasis
    • Jaffe A.B., and Hall A. Rho GTPases in transformation and metastasis. Adv Cancer Res 84 (2002) 57-80
    • (2002) Adv Cancer Res , vol.84 , pp. 57-80
    • Jaffe, A.B.1    Hall, A.2
  • 28
    • 1642273617 scopus 로고    scopus 로고
    • Rho-regulatory proteins in breast cancer cell motility and invasion
    • Lin M., and van Golen K.L. Rho-regulatory proteins in breast cancer cell motility and invasion. Breast Cancer Res Treat 84 (2004) 49-60
    • (2004) Breast Cancer Res Treat , vol.84 , pp. 49-60
    • Lin, M.1    van Golen, K.L.2
  • 29
    • 0017653755 scopus 로고
    • Phenotypic characterisation of a unique non-T, non-B acute lymphoblastic leukaemia cell line
    • Rosenfeld C., Goutner A., Choquet C., et al. Phenotypic characterisation of a unique non-T, non-B acute lymphoblastic leukaemia cell line. Nature 267 (1977) 841-843
    • (1977) Nature , vol.267 , pp. 841-843
    • Rosenfeld, C.1    Goutner, A.2    Choquet, C.3
  • 30
    • 0030999765 scopus 로고    scopus 로고
    • Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines
    • Uphoff C.C., MacLeod R.A., Denkmann S.A., et al. Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines. Leukemia 11 (1997) 441-447
    • (1997) Leukemia , vol.11 , pp. 441-447
    • Uphoff, C.C.1    MacLeod, R.A.2    Denkmann, S.A.3
  • 33
    • 0025678485 scopus 로고
    • Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: an index of cell proliferation with evidence of deregulated expression in some neoplasms
    • Hall P.A., Levison D.A., Woods A.L., et al. Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: an index of cell proliferation with evidence of deregulated expression in some neoplasms. J Pathol 162 (1990) 285-294
    • (1990) J Pathol , vol.162 , pp. 285-294
    • Hall, P.A.1    Levison, D.A.2    Woods, A.L.3
  • 34
    • 0033081753 scopus 로고    scopus 로고
    • Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
    • Ren X.D., Kiosses W.B., and Schwartz M.A. Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J 18 (1999) 578-585
    • (1999) EMBO J , vol.18 , pp. 578-585
    • Ren, X.D.1    Kiosses, W.B.2    Schwartz, M.A.3
  • 35
    • 0029889591 scopus 로고    scopus 로고
    • Rhotekin, a putative target for Rho bearing homology to a serine/threonine kinase, PKN and Rhophilin in the Rho binding domain
    • Reid T., Furuyashiki T., Ishizaki T., et al. Rhotekin, a putative target for Rho bearing homology to a serine/threonine kinase, PKN and Rhophilin in the Rho binding domain. J Biol Chem 271 (1996) 13556-13560
    • (1996) J Biol Chem , vol.271 , pp. 13556-13560
    • Reid, T.1    Furuyashiki, T.2    Ishizaki, T.3
  • 36
    • 0030992879 scopus 로고    scopus 로고
    • C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases
    • Gosser Y.Q., Nomanbhoy T.K., Aghazadeh B., et al. C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases. Nature 387 (1997) 814-819
    • (1997) Nature , vol.387 , pp. 814-819
    • Gosser, Y.Q.1    Nomanbhoy, T.K.2    Aghazadeh, B.3
  • 37
    • 0023718983 scopus 로고
    • Secondary structure prediction: combination of three different methods
    • Biou V., Gibrat J.F., Levin J.M., Robson B., and Garnier J. Secondary structure prediction: combination of three different methods. Protein Eng 2 (1988) 185-191
    • (1988) Protein Eng , vol.2 , pp. 185-191
    • Biou, V.1    Gibrat, J.F.2    Levin, J.M.3    Robson, B.4    Garnier, J.5
  • 39
    • 0029562867 scopus 로고
    • The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases
    • Hotchin N.A., and Hall A. The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases. J Cell Biol 131 (1995) 1857-1865
    • (1995) J Cell Biol , vol.131 , pp. 1857-1865
    • Hotchin, N.A.1    Hall, A.2
  • 40
    • 0030904698 scopus 로고    scopus 로고
    • Regulation of cadherin-mediated adhesion by the small GTP-binding protein Rho in small cell lung carcinoma cells
    • Tokman M.G., Porter R.A., and Williams C.L. Regulation of cadherin-mediated adhesion by the small GTP-binding protein Rho in small cell lung carcinoma cells. Cancer Res 57 (1997) 1785-1793
    • (1997) Cancer Res , vol.57 , pp. 1785-1793
    • Tokman, M.G.1    Porter, R.A.2    Williams, C.L.3
  • 41
    • 0032935495 scopus 로고    scopus 로고
    • An essential part Rho-associated kinase in the transcellular invasion of tumor cells
    • Itoh K., Yoshioka K., Akedo H., Uehata M., Ishizaki T., and Narumiya S. An essential part Rho-associated kinase in the transcellular invasion of tumor cells. Nat Med 5 (1999) 221-225
    • (1999) Nat Med , vol.5 , pp. 221-225
    • Itoh, K.1    Yoshioka, K.2    Akedo, H.3    Uehata, M.4    Ishizaki, T.5    Narumiya, S.6
  • 42
    • 0029795488 scopus 로고    scopus 로고
    • Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway
    • Hirao M., Sato N., Kondo T., et al. Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway. J Cell Biol 135 (1996) 37-51
    • (1996) J Cell Biol , vol.135 , pp. 37-51
    • Hirao, M.1    Sato, N.2    Kondo, T.3
  • 43
    • 33745233810 scopus 로고    scopus 로고
    • D4-GDI, a Rho GTPase regulator, promotes breast cancer cell invasiveness
    • Zhang Y., and Zhang B. D4-GDI, a Rho GTPase regulator, promotes breast cancer cell invasiveness. Cancer Res 66 (2006) 5592-5598
    • (2006) Cancer Res , vol.66 , pp. 5592-5598
    • Zhang, Y.1    Zhang, B.2
  • 44
    • 33845439460 scopus 로고    scopus 로고
    • Defective chemokine-directed lymphocyte migration and development in the absence of rho guanosine diphosphate-dissociation inhibitors alpha and beta
    • Ishizaki H., Togawa A., Tanaka-Okamoto M., et al. Defective chemokine-directed lymphocyte migration and development in the absence of rho guanosine diphosphate-dissociation inhibitors alpha and beta. J Immunol 177 (2006) 8512-8521
    • (2006) J Immunol , vol.177 , pp. 8512-8521
    • Ishizaki, H.1    Togawa, A.2    Tanaka-Okamoto, M.3
  • 45
    • 0029951250 scopus 로고    scopus 로고
    • Defective Rho GTPase regulation by IL-1 beta-converting enzyme-mediated cleavage of D4 GDP dissociation inhibitor
    • Danley D.E., Chuang T.H., and Bokoch G.M. Defective Rho GTPase regulation by IL-1 beta-converting enzyme-mediated cleavage of D4 GDP dissociation inhibitor. J Immunol 157 (1996) 500-503
    • (1996) J Immunol , vol.157 , pp. 500-503
    • Danley, D.E.1    Chuang, T.H.2    Bokoch, G.M.3
  • 46
    • 0031985337 scopus 로고    scopus 로고
    • Inhibition of CPP32 blocks surface IgM-mediated apoptosis and D4-GDI cleavage in human BL60 Burkitt lymphoma cells
    • Rickers A., Brockstedt E., Mapara M.Y., Otto A., Dorken B., and Bommert K. Inhibition of CPP32 blocks surface IgM-mediated apoptosis and D4-GDI cleavage in human BL60 Burkitt lymphoma cells. Eur J Immunol 28 (1998) 296-304
    • (1998) Eur J Immunol , vol.28 , pp. 296-304
    • Rickers, A.1    Brockstedt, E.2    Mapara, M.Y.3    Otto, A.4    Dorken, B.5    Bommert, K.6
  • 47
    • 0030869004 scopus 로고    scopus 로고
    • Immune responses in mice deficient in Ly-GDI, a lymphoid-specific regulator of Rho GTPases
    • Yin L., Schwartzberg P., Scharton-Kersten T.M., Staudt L., and Lenardo M. Immune responses in mice deficient in Ly-GDI, a lymphoid-specific regulator of Rho GTPases. Mol Immunol 34 (1997) 481-491
    • (1997) Mol Immunol , vol.34 , pp. 481-491
    • Yin, L.1    Schwartzberg, P.2    Scharton-Kersten, T.M.3    Staudt, L.4    Lenardo, M.5
  • 48
    • 10144252434 scopus 로고    scopus 로고
    • Targeted disruption of guanosine diiphosphate-dissociation inhibitor for Rho-related protein, GDID4: normal hematopoietic differentiation but subtle defect in superoxide production by macrophages derived from in vitro embryonal stem cell differentiation
    • Guillemot J.-C., Kruskal B.A., Adra C.N., et al. Targeted disruption of guanosine diiphosphate-dissociation inhibitor for Rho-related protein, GDID4: normal hematopoietic differentiation but subtle defect in superoxide production by macrophages derived from in vitro embryonal stem cell differentiation. Blood 88 (1996) 2722-2731
    • (1996) Blood , vol.88 , pp. 2722-2731
    • Guillemot, J.-C.1    Kruskal, B.A.2    Adra, C.N.3
  • 49
    • 0035074541 scopus 로고    scopus 로고
    • Comparative genome-scale analysis of gene expression profiles in t cell lymphoma cells during malignant progression using a complementary DNA microarray
    • Li S., Ross D.T., Kadin M.E., Brown P.O., and Wasik M.A. Comparative genome-scale analysis of gene expression profiles in t cell lymphoma cells during malignant progression using a complementary DNA microarray. Am J Pathol 158 (2001) 1231-1237
    • (2001) Am J Pathol , vol.158 , pp. 1231-1237
    • Li, S.1    Ross, D.T.2    Kadin, M.E.3    Brown, P.O.4    Wasik, M.A.5
  • 50
    • 0035397380 scopus 로고    scopus 로고
    • Changes in gene expression during progression of ovarian carcinoma
    • Tapper J., Kettunen E., El Rifai W., et al. Changes in gene expression during progression of ovarian carcinoma. Cancer Genet Cytogenet 128 (2001) 1-6
    • (2001) Cancer Genet Cytogenet , vol.128 , pp. 1-6
    • Tapper, J.1    Kettunen, E.2    El Rifai, W.3
  • 51
    • 0037112363 scopus 로고    scopus 로고
    • RhoGDI2 is an invasion and metastasis suppressor gene in human cancer
    • Gildea J.J., Seraj M.J., Oxford G., et al. RhoGDI2 is an invasion and metastasis suppressor gene in human cancer. Cancer Res 62 (2002) 6418-6423
    • (2002) Cancer Res , vol.62 , pp. 6418-6423
    • Gildea, J.J.1    Seraj, M.J.2    Oxford, G.3
  • 52
    • 2542606977 scopus 로고    scopus 로고
    • Reduced expression of metastasis suppressor RhoGDI2 is associated with decreased survival for patients with bladder cancer
    • Theodorescu D., Sapinoso L.M., Conaway M.R., et al. Reduced expression of metastasis suppressor RhoGDI2 is associated with decreased survival for patients with bladder cancer. Clin Cancer Res 10 (2004) 3800-3806
    • (2004) Clin Cancer Res , vol.10 , pp. 3800-3806
    • Theodorescu, D.1    Sapinoso, L.M.2    Conaway, M.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.