Downregulation of cyclin D1-CDK4 protein in human embryonic lung fibroblasts (HELF) induced by silica is mediated through the ERK and JNK pathway

Cell Biology International

Volumn 32, Issue 10, 2008, Pages 1284-1292

  Shen, Fuhai ^a   Fan, Xueyun ^a   Liu, Bingci ^b   Jia, Xiaowei ^b   Gao, Ai ^b   Du, Hongju ^b   Ye, Meng ^b   You, Baorong ^b   Huang, Chuanshu ^c   Shi, Xianglin ^d  

^a NORTH CHINA COAL MEDICAL COLLEGE   (China)

^b CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

AP 1; CDK4; cyclin D1; MAPK; Silica

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CURCUMIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SILICON DIOXIDE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CONTROLLED STUDY; DOSE RESPONSE; FETUS LUNG; HUMAN; HUMAN CELL; LUNG FIBROBLAST; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

CELLS, CULTURED; CYCLIN D1; CYCLIN-DEPENDENT KINASE 4; DOWN-REGULATION; EMBRYO, MAMMALIAN; ENZYME ACTIVATION; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LUNG; MAP KINASE SIGNALING SYSTEM; SILICON DIOXIDE; SILICOSIS; TRANSCRIPTION FACTOR AP-1;

EID: 52949087565     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellbi.2008.07.015     Document Type: Article

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