Investigation of heat treating conditions for enhancing the anti-inflammatory activity of citrus fruit (Citrus reticulata) peels

Journal of Agricultural and Food Chemistry

Volumn 56, Issue 17, 2008, Pages 7976-7982

  Ho, Su Chen ^a   Lin, Chih Cheng ^a  

^a YUANPEI UNIVERSITY   (Taiwan)

Author keywords

Anti inflammation; Antioxidation; Citrus fruit; Heat treatment; Nitric oxide

Indexed keywords

ANTIINFLAMMATORY AGENT; FLAVONOID; LIPOPOLYSACCHARIDE; NITRIC OXIDE; SCAVENGER;

ARTICLE; BIOSYNTHESIS; CELL LINE; CHEMISTRY; CITRUS FRUIT; DRUG EFFECT; FRUIT; HEAT; MACROPHAGE; METABOLISM;

ANTI-INFLAMMATORY AGENTS; CELL LINE; CITRUS; FLAVONOIDS; FREE RADICAL SCAVENGERS; FRUIT; HEAT; LIPOPOLYSACCHARIDES; MACROPHAGES; NITRIC OXIDE;

CITRUS; CITRUS RETICULATA;

EID: 52649089682     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf801434c     Document Type: Article

References (29)

1. Li, S.; Lo, C.-Y.; Ho, C.-T. Hydroxylated polymethoxyflavones and methylated flavonoids in sweet orange (Citrus sinensis) peel. J. Agric. Food Chem. 2006, 54, 4176-4185.
2. Schieber, A.; Stintzing, F. C.; Carle, R. By-products of plant food processing as a source of functional compounds- recent developments. Trends Food Sci. Technol. 2001, 12, 401-413.
3. Bocco, A.; Cuvelier, M. E.; Richard, H.; Berset, C. Antioxidant activity and phenolic composition of citrus peel and seed extract. J. Agric. Food Chem. 1998, 46, 2123-2129.
4. Gorinstein, S.; Martín-Belloso, O.; Park, Y.-S.; Haruenkit, R.; Lojek, A.; Ciz, M.; Capsi, A.; Libman, I.; Trakhtenberg, S. Comparison of some biochemical characteristics of different citrus fruits. Food Chem. 2001, 309-315.
5. Ou, M. Regular Chinese Medicine Handbook; Warmth Publishing Ltd.: Taiwan, 1999.
6. Rahman, I. Oxidative stress, chromatin remodelling and gene transcription in inflammation and chronic lung diseases. J. Biochem. Mol. Biol. 2003, 36, 95-109.
7. Szabo, C. Multiple pathway of peroxynitrite cytotoxicity. Toxicol. Lett. 2003, 140-141, 105-112.
8. van der Vliet, A.; Eiserich, J. P.; Shigenaga, M. K.; Cross, C. E. Reactive nitrogen species and tyrosine nitration in the respiratory tract: epiphenomena or a pathobiologic mechanism of disease? Am. J. Respir. Crit. Care Med. 1999, 160, 1-9.
9. Dweik, R. A.; Comhair, S. A.; Gaston, B.; Thunnissen, F. B.; Farver, C.; Thomassen, M. J.; Kavuru, M.; Hammel, J.; Abu-Soud, H. M.; Erzurum, S. C NO chemical events in the human airway during the immediate and late antigen-induced asthmatic response. Proc. Natl. Acad. Sci. U.S.A. 2001, 98, 2622-2627.
10. Bowler, R. P.; Crapo, J. D. Oxidative stress in allergic respiratory diseases. J. Allergy Clin. Immunol. 2002, 110, 349-356.
11. Jeong, S.-M.; Kim, S.-Y.; Kim, D.-R.; Jo, S.-C.; Nam, K. C.; Ahn, D. U.; Lee, S.-C. Effect of heat treatment on the antioxidant activity of extracts from citrus peels. J. Agric. Food Chem. 2004, 52, 3389-3393.
12. Xu, G.; Ye, X.; Chen, J.; Liu, D. Effect of heat treatment on the phenolic compounds and antioxidant capacity of citrus peel extract. J. Agric. Food Chem. 2007, 55, 330-335.
13. Lin, C.-C.; Hung, P.-F.; Ho, S.-C. Heat treatment enhances the NO-suppressing and peroxynitrite-intercepting activities of kumquat's (Fortunella margarita Swingle) peel. Food Chem. 2008, 109, 95-103.
14. Tripoli, E.; Guardia, M. L.; Giammanco, S.; Majo, D. D.; Giammanco, M. Citrus flavonoids: molecular structure, biological activity and nutritional properties: a review. Food Chem. 2007, 104, 466-479.
15. Benavente-Garcia, O.; Castillo, J.; Marin, F. R.; Ortuno, A.; Del Rio, J. A. Uses and properties of citrus flavonoids. J. Agric. Food Chem. 1997, 45, 4505-4515.
16. Lu, Y.; Zhang, C.; Bucheli, P.; Wei, D. Citrus flavonoids in fruit and traditional Chinese medical food ingredients in China. Plant Food Hum. Nutr. 2006, 61, 57-65.
17. Murakami, A.; Ohigashi, H. Polymethylated flavonoid: Cancer preventive and therapeutic potentials derived from antiinflammatory and drug metabolism-modifying properties. Oxid. Stress Dis. Phytochem. Health Dis. 2004, 12, 187-211.
18. Whitman, S. C.; Kurowska, E. M.; Manthey, J. A.; Daugherty, A. Nobiletin, a citrus flavonoid isolated from tangerines, selectively inhibits class A scavenger receptor-mediated metabolism of acetylated LDL by mouse macrophages. Atherosclerosis 2005, 178, 25-32.
19. Choi, S.-Y.; Ko, H.-C.; Ko, S.-Y.; Hwang, J.-H.; Park, J.-G.; Kang, S.-H.; Han, S.-H.; Yun, S.-H.; Kim, S.-J. Correlation between flavonoid content and the NO production inhibitory activity of peel extracts from various citrus fruits. Biol. Pharm. Bull. 2007, 30 (4), 772-778.
20. Abeysinghe, D. C.; Li, X.; Sun, C. D.; Zhang, W. S.; Zhou, C. H.; Chen, K. S. Bioactive compounds and antioxidant capacities in different edible tissue of four species. Food Chem. 2007, 104, 1338-1344.
21. Jung, K. H.; Ha, E.; Kim, M. J.; Won, H. J.; Zheng, L. T.; Kim, H. K.; Hong, S. J.; Chung, J. H.; Yim, S. V. Suppressive effects of nitric oxide (NO) production and inducible nitric oxide synthase (iNOS) expression by Citrus reticulata extract in RAW 264.7 macrophage cells. Food Chem. Toxicol. 2007, 45, 1545-1550.
22. Sakata, K.; Hirose, Y.; Qiao, Z.; Tanaka, T.; Mori, H. Inhibition of inducible isoforms of cyclooxygenase and nitric oxide synthase by flavonoid hesperidin in mouse macrophage cell line. Cancer Lett. 2003, 199 (2), 139-145.
23. Kanno, S.; Shouji, A.; Tomizawa, A.; Hiura, T.; Osanai, Y.; Ujibe, M.; Obara, Y.; Nakahata, N.; Ishikawa, M. Inhibitory effect of naringin on lipopolysaccharide (LPS)-induced endotoxin shock in mice and nitric oxide production in RAW 264.7 macrophages. Life Sci. 2006, 78 (7), 673-681.
24. Murakami, A.; Gao, G.; Kim, O. K.; Omura, M.; Yano, M.; Ito, C.; Furukawa, H.; Jiwajinda, S.; Koshimizu, K.; Ohigashi, H. Identification of coumarins from the fruit of Citrus hystrix DC as inhibitors of nitric oxide generation in mouse macrophage RAW 264.7 cells. J. Agric. Food Chem. 1999, 47, 333-339.
25. Murakami, A.; Nakamura, Y.; Ohto, Y.; Yano, M.; Koshiba, T.; Koshimizu, K.; Tokuda, H.; Nishino, H.; Ohigashi, H. Suppressive effects of citrus fruits on free radical generation and nobiletin, an anti-inflammatory polymethoxyflavonoid. Biofactors 2000, 12, 187-192.
26. Nogata, Y.; Ohta, H.; Sumida, T.; Sekiya, K. Effect of extraction method on the concentrations of selected bioactive compounds in mandarin juice. J. Agric. Food Chem. 2003, 51, 7346-7351.
27. Li, S.; Yu, H.; Ho, C.-T. Nobiletin: efficient and large quantity isolation from orange peel extract. Biomed. Chromatogr. 2006, 20, 133-138.
28. 2 production by a macrophage cell line. J. Biomed. Sci. 2002, 9, 596-606.
29. Ho, S.-C.; Tsai, P.-J. Comparison of the effects of "hot" and "cold" Chinese medicinal plants on the production of inflammatory mediators by RAW 264.7 cells. J. Food Drug Anal. 2004, 12, 120-127.