An FDA approved neurokinin-1 receptor antagonist is effective in reducing intraabdominal adhesions when administered intraperitoneally, but not orally

Journal of Gastrointestinal Surgery

Volumn 12, Issue 10, 2008, Pages 1754-1761

  Lim, Rizal ^a   Morrill, Jonathan M ^a   Prushik, Scott G ^a   Reed, Karen L ^a   Gower, Adam C ^a   Leeman, Susan E ^a   Stucchi, Arthur F ^a   Becker, James M ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aprepitant; Emend; Intraabdominal adhesion; Neurokinin 1 receptor antagonist; Substance P

Indexed keywords

ANTIINFLAMMATORY AGENT; APREPITANT; MORPHOLINE DERIVATIVE; NEUROKININ 1 RECEPTOR;

ANIMAL; CONFERENCE PAPER; DISEASE MODEL; DRUG ANTAGONISM; EVALUATION; INFUSION; ORAL DRUG ADMINISTRATION; PERITONEAL DISEASE; RAT; TISSUE ADHESION;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; DISEASE MODELS, ANIMAL; INFUSIONS, PARENTERAL; MORPHOLINES; PERITONEAL DISEASES; RATS; RECEPTORS, NEUROKININ-1; TISSUE ADHESIONS;

EID: 52549130708     PISSN: 1091255X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11605-008-0634-4     Document Type: Conference Paper

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