Substance P regulates the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinase in cultured human gingival fibroblasts

Journal of Periodontal Research

Volumn 43, Issue 3, 2008, Pages 255-260

  Cury, P R ^a,b   Canavez, F ^c   De Araujo V C ^a   Furuse, C ^a   De Araujo N S ^b  

^a SÃO LEOPOLDO MANDIC INSTITUTE AND RESEARCH CENTER   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c Genoa Group   (Brazil)

Author keywords

Gingival fibroblasts; Matrix metalloproteinase; Substance P; Tissue inhibitor of metalloproteinase

Indexed keywords

MATRIX METALLOPROTEINASE; SUBSTANCE P; TISSUE INHIBITOR OF METALLOPROTEINASE;

ARTICLE; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; DOSE RESPONSE; ENZYME ACTIVATION; ENZYMOLOGY; FIBROBLAST; GENE EXPRESSION; GINGIVA; HUMAN; NONPARAMETRIC TEST; PHYSIOLOGY; POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

BLOTTING, WESTERN; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FIBROBLASTS; GENE EXPRESSION; GINGIVA; HUMANS; MATRIX METALLOPROTEINASES; POLYMERASE CHAIN REACTION; STATISTICS, NONPARAMETRIC; SUBSTANCE P; TISSUE INHIBITOR OF METALLOPROTEINASES; UP-REGULATION;

EID: 43049115350     PISSN: 00223484     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0765.2007.01022.x     Document Type: Article

References (37)

1. Mäkela M, Salo T, Uitto VJ, Larjava H. Matrix metalloproteinases (MMP-2 and MMP-9) of the oral cavity: cellular origin and relationship to periodontal status. J Dent Res 1994 73 : 1397 1406.
2. Ingman T, Tervahartiala T, Ding Y et al. Matrix metalloproteinases and their inhibitors in gingival crevicular fluid and saliva of periodontitis patients. J Clin Periodontol 1996 23 : 1127 1132.
3. Alpagot T, Bell C, Lundergan W, Chambers DW, Rudin R. Longitudinal evaluation of GCF MMP-3 and TIMP-1 levels as prognostic factors for progression of periodontitis. J Clin Periodontol 2001 28 : 353 359.
4. Tervahartiala T, Pirilä E, Ceponis A et al. The in vivo expression of the collagenolytic matrix metalloproteinases (MMP-2, -8, -13, and -14) and matrilysin (MMP-7) in adult and localized juvenile periodontitis. J Dent Res 2000 79 : 1969 1977.
5. Emingil G, Tervahartiala T, Mantyla P, Maatta M, Sorsa T, Atilla G. Gingival crevicular fluid matrix metalloproteinase (MMP)-7, extracellular MMP inducer, and tissue inhibitor of MMP-1 levels in periodontal disease. J Periodontol 2006 77 : 2040 2050.
6. Larivee J, Sodek J, Ferrier JM. Collagenase and collagenase inhibitor activities in crevicular fluid of patients receiving treatment for localized juvenile periodontitis. J Periodont Res 1986 21 : 702 715.
7. Lundy FT, Linden GJ. Neuropeptides and neurogenic mechanisms in oral and periodontal inflammation. Crit Rev Oral Biol Med 2004 15 : 82 98.
8. Abd El-Aleem SA, Morales-Aza BM, Donaldson LF. Sensory neuropeptide mRNA up-regulation is bilateral in periodontitis in the rat: a possible neurogenic component to symmetrical periodontal disease. Eur J Neurosci 2004 19 : 650 658.
9. Lundy FT, Mullally BH, Burden DJ, Lamey PJ, Shaw C, Linden GJ. Changes in Substance P and neurokinin A in gingival crevicular fluid in response to periodontal treatment. J Clin Periodontol 2000 27 : 526 530.
10. Hanioka T, Takaya K, Matsumori Y, Matsuse R, Shizukuishi S. Relationship of the Substance P to indicators of host response in human gingival crevicular fluid. J Clin Periodontol 2000 27 : 262 266.
11. Linden GJ, McKinnell J, Shaw C, Lundy FT. Substance P and neurokinin A in gingival crevicular fluid in periodontal health and disease. J Clin Periodontol 1997 24 : 799 803.
12. Shibata H, Mio M, Tasaka K. Analysis of the mechanism of histamine release induced by substance P. Biochim Biophys Acta 1985 846 : 1 7.
13. Lieb K, Fiebich BL, Busse-Grawitz M, Hull M, Berger M, Bauer J. Effects of substance P and selected other neuropeptides on the synthesis of interleukin-1 beta and interleukin-6 in human monocytes: a re-examination. J Neuroimmunol 1996 67 : 77 81.
14. Rameshwar P, Gascon P, Ganea D. Stimulation of IL-2 production in murine lymphocytes by substance P and related tachykinins. J Immunol 1993 : 2484 2496.
15. Scicchitano R, Biennenstock J, Stanisz AM. In vivo immunomodulation by the neuropeptide substance P. Immunology 1988 63 : 733 735.
16. Nio DA, Moylan RN, Roche JK. Modulation of T lymphocyte function by neuropeptides. Evidence for their role as local immunoregulatory elements. J Immunol 1993 150 : 5281 5288.
17. Bartold PM, Kylstra A, Lawson R. Substance P: an immunohistochemical and biochemical study in human gingival tissues. A role for neurogenic inflammation? J Periodontol 1994 65 : 1113 1121.
18. Azuma H, Kido J, Ikedo D, Kataoka M, Nagata T. Substance P enhances the inhibition of osteoblastic cell differentiation induced by lipopolysaccharide from Porphyromonas gingivalis. J Periodontol 2004 75 : 974 981.
19. Birkedal-Hansen H, Moore WG, Bodden MK et al. Matrix metalloproteinases: a review. Crit Rev Oral Biol Med 1993 4 : 197 250.
20. Cury PR, Araujo VC, Canavez F, Furuse C, Araujo NS. Hydrocortisone affects the expression of matrix metalloproteinases (MMP-1, MMP-2, MMP-3, MMP-7 and MMP-11) and tissue inhibitor of matrix metalloproteinases (TIMP-1) in human gingival fibr. J Periodontol 2007 78 : 1309 1315.
21. Cury PR, de Araujo VC, Canavez F, Furuse C, Leite KR, de Araujo NS. The effect of epidermal growth factor on matrix metalloproteinases and tissue inhibitors of metalloproteinase gene expression in cultured human gingival fibroblasts. Arch Oral Biol 2007 52 : 585 590.
22. Yamada H, Nishimura F, Naruishi K et al. Phenytoin and cyclosporin A suppress the expression of MMP-1, TIMP-1, and cathepsin L, but not cathepsin B in cultured gingival fibroblasts. J Periodontol 2000 71 : 955 960.
23. Gan L, Ye S, Chu A et al. Identification of cathepsin B as a mediator of neuronal death induced by beta-activated microglial cells using a functional genomics approach. J Biol Chem 2004 279 : 5565 5572.
24. Cao YQ, Mantyh PW, Carlson EJ, Gillespie AM, Epstein CJ, Basbaum AI. Primary afferent tachykinins are required to experience moderate to intense pain. Nature 1998 392 : 390 394.
25. Kwong KY, Bloom GC, Yang I et al. Synchronous global assessment of gene and protein expression in colorectal cancer progression. Genomics 2005 86 : 142 158.
26. Narayanan AS, Page RC. Connective tissues of the periodontium: a summary of current work. Coll Relat Res 1983 3 : 33 64.
27. Shibata H, Mio M, Tasaka K. Analysis of the mechanism of histamine release induced by Substance P. Biochim Biophys Acta 1985 846 : 1 7.
28. Lembeck F, Donnerer J, Tsuchiya M, Nagahisa A. The non-peptide tachykinin antagonist, CP-96,345, is a potent inhibitor of neurogenic inflammation. Br J Pharmacol 1992 105 : 527 530.
29. Lieb K, Fiebich BL, Busse-Grawitz M, Hull M, Berger M, Bauer J. Effects of Substance P and selected other neuropeptides on the synthesis of interleukin-1 beta and interleukin-6 in human monocytes: a re-examination. J Neuroimmunol 1996 67 : 77 81.
30. Mantyh PW. Substance P and the inflammatory and immune response. Ann New York Acad Sci 1991 632 : 263 271.
31. Aiba T, Akeno N, Kawane T, Okamoto H, Horiuchi N. Matrix metalloproteinases-1 and -8 and TIMP-1 mRNA levels in normal and diseased human gingivae. Eur J Oral Sci 1996 104 : 562 569.
32. Kubota T, Nomura T, Takahashi T, Hara K. Expression of mRNA for matrix metalloproteinases and tissue inhibitors of metalloproteinases in periodontitis- affected human gingival tissue. Arch Oral Biol 1996 41 : 253 262.
33. Korostoff JM, Wang JF, Sarment DP, Stewart JC, Feldman RS, Billings PC. Analysis of in situ protease activity in chronic adult periodontitis patients: expression of activated MMP-2 and a 40kDa serine protease. J Periodontol 2000 71 : 353 360.
34. Irwin CR, Myrillas TT, Traynor P, Leadbetter N, Cawston TE. The role of soluble interleukin (IL)-6 receptor in mediating the effects of IL-6 on matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 expression by gingival fibroblasts. J Periodontol 2002 73 : 741 747.
35. Hecker-Kia A, Kolkenbrock H, Orgel D, Zimmermann B, Sparmann M, Ulbrich N. Substance P induces the secretion of gelatinase A from human synovial fibroblasts. Eur J Clin Chem Clin Biochem 1997 35 : 655 660.
36. Birkedal-Hansen H. Role of cytokines and inflammatory mediators in tissue destruction. J Periodont Res 1993 28 : 500 510.
37. Uitto VJ, Salonen JI, Firth JD, Jousimies-Somer H, Saarialho-Kere U. Matrilysin (matrix metalloproteinase-7) expression in human junctional epithelium. J Dent Res 2002 81 : 241 246.