How the binding and degrading capabilities of insulin degrading enzyme are affected by ubiquitin

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1784, Issue 7-8, 2008, Pages 1122-1126

  Grasso, Giuseppe ^a   Rizzarelli, Enrico ^a,b   Spoto, Giuseppe ^a,b  

^a UNIVERSITY OF CATANIA   (Italy)

^b CNR   (Italy)

Author keywords

Insulin degrading enzyme; Mass spectrometry; Noncovalent interaction; Surface plasmon resonance; Ubiquitin

Indexed keywords

INSULINASE; UBIQUITIN;

ARTICLE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME DEGRADATION; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; SURFACE PLASMON RESONANCE;

ANIMALS; INSULYSIN; PROTEIN BINDING; RATS; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SPODOPTERA; SURFACE PLASMON RESONANCE; UBIQUITIN;

EID: 52449135535     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2008.04.011     Document Type: Article

References (17)

1. Farris W., Mansourian S., Chang Y., Lindsley L., Eckman E.A., Frosch M.P., Eckman C.B., Tanzi R.E., Selkoe D.J., and Guenette S. Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 4162-4167
2. Shen Y., Joachimiak A., Rosner M.R., and Tang W.-J. Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism. Nature 443 (2006) 870-874
3. Soto C. Unfolding the role of protein misfolding in neurodegenerative diseases. Nat. Rev. Neurosci. 4 (2003) 49-60
4. Chiti F., and Dobson C.M. Protein misfolding, functional amyloid, and human disease. Annu. Rev. Biochem. 75 (2006) 333-366
5. Bertram L., Blacker D., Mullin K., Keeney D., Jones J., Basu S., Yhu S., McInnis M.G., Go R.C.P., Vekrellis K., Selkoe D.J., Saunders A.J., and Tanzi R.E. Evidence for genetic linkage of Alzheimer's disease to chromosome 10q. Science 290 (2000) 2302-2303
6. Qiu W.Q., and Folstein M.F. Insulin, insulin-degrading enzyme and amyloid-b peptide in Alzheimer's disease: review and hypothesis. Neurobiol. aging 27 (2006) 190-198
7. Bennett R.G., Hamel F.G., and Duckworth W.C. Characterization of the insulin inhibition of the peptidolytic activities of the insulin-degrading enzyme-proteasome complex. Diabetes 46 (1997) 197-203
8. Saric T., Muller D., Seitz H.-J., and Pavelic K. Non-covalent interaction of ubiquitin with insulin-degrading enzyme. Mol. Cell. Endocrinol. 204 (2003) 11-20
9. Duckworth W.C., Bennett R.G., and Hamel F.G. Insulin acts intracellularly on proteasomes through insulin-degrading enzyme. Biochem. Biophys. Res. Commun. 244 (1998) 390-394
10. Bennett E.J., Shaler T.A., Woodman B., Ryu K.-Y., Zaitseva T.S., Becker C.H., Bates G.P., Schulman H., and Kopito R.R. Global changes to the ubiquitin system in Huntington's disease. Nature 448 (2007) 704-709
11. Ross C.A., and Pickart C.M. The ubiquitin-proteasome pathway in Parkinson's disease and other neurodegenerative diseases. Trends Cell Biol. 14 (2004) 703-711
12. Lam Y.A., Pickart C.M., Alban A., Landon M., Jamieson C., Ramage R., Mayer R.J., and Layfield R. Inhibition of the ubiquitin-proteasome system in Alzheimer's disease. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 9902-9906
13. Grasso G., Rizzarelli E., and Spoto G. AP/MALDI-MS complete characterization of insulin fragments produced by the interaction of IDE with bovine insulin. J. Mass Spectrom. 42 (2007) 1590-1598
14. Grasso G., D'Agata R., Rizzarelli E., Spoto G., D'Andrea L., Pedone C., Picardi A., Romanelli A., Fragai M., and Yeo K.J. Activity of anchored human matrix metalloproteinase-1 catalytic domain on Au (111) surfaces monitored by ESI-MS. J. Mass Spectrom. 40 (2005) 1565-1571
15. Shevchenko A., and Shevchenko A. Evaluation of the efficiency of in-gel digestion of proteins by peptide isotopic labeling and MALDI mass spectrometry. Anal. Biochem. 296 (2001) 279-283
16. Duckworth W.C., Bennett R.G., and Hamel F.G. A direct inhibitory effect of insulin on a cytosolic proteolytic complex containing insulin-degrading enzyme and multicatalytic proteinase. J. Biol. Chem. 269 (1994) 24575-24580
17. Hershko A., and Ciechanover A. The ubiquitin system. Annu. Rev. Biochem. 67 (1998) 425-479