The constitutive expression of anticoagulant protein S is regulated through multiple binding sites for Sp1 and Sp3 transcription factors in the protein S gene promoter

Journal of Biological Chemistry

Volumn 281, Issue 26, 2006, Pages 17635-17643

  De Wolf, Cornelia J F ^a   Cupers, Rosemiek M J ^a   Bertina, Rogier M ^a   Vos, Hans L ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BLOOD; COAGULATION; CYTOLOGY; ELECTROPHORESIS; ENZYME KINETICS; GENETIC ENGINEERING; IMMUNOLOGY; MUTAGENESIS;

BLOOD COAGULATION; CHROMATIN IMMUNOPRECIPITATIONS; TRANSIENT TRANSFECTIONS; VENOUS THROMBOSIS;

PROTEINS;

ACTIVATING TRANSCRIPTION FACTOR; ANTICOAGULANT PROTEIN; HEPATOCYTE NUCLEAR FACTOR 3BETA; NUCLEAR FACTOR; NUCLEAR FACTOR Y; NUCLEIC ACID BINDING PROTEIN; PLASMA PROTEIN; PROTEIN S; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CELL CULTURE; GEL MOBILITY SHIFT ASSAY; GENE CONSTRUCT; MUTATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK FACTOR; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION REGULATION;

BASE SEQUENCE; BINDING SITES; CARCINOMA, HEPATOCELLULAR; CCAAT-BINDING FACTOR; CHROMATIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; HELA CELLS; HEPATOCYTE NUCLEAR FACTOR 3-BETA; HUMANS; LIVER NEOPLASMS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROMOTER REGIONS (GENETICS); PROTEIN S; SP1 TRANSCRIPTION FACTOR; SP3 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTORS; TRANSFECTION; UMBILICAL VEINS;

EID: 33745857955     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M603094200     Document Type: Article

References (58)

1. Schenone, M., Furie, B. C., and Furie, B. (2004) Curr. Opin. Hematol. 11, 272-277
2. Walker, F. J. (1980) J. Biol. Chem. 255, 5521-5524
3. Fulcher, C. A., Gardiner, J. E., Griffin, J. H., and Zimmerman, T. S. (1984) Blood 63, 486-489
4. Rosing, J., Hoekema, L., Nicolaes, G. A., Thomassen, M. C., Hemker, H. C., Varadi, K., Schwarz, H. P., and Tans, G. (1995) J. Biol. Chem. 270, 27852-27858
5. Yegneswaran, S., Wood, G. M., Esmon, C. T., and Johnson, A. E. (1997) J. Biol. Chem. 272, 25013-25021
6. Hackeng, T. M., van 't Veer, C., Meijers, J. C., and Bouma, B. N. (1994) J. Biol. Chem. 269, 21051-21058
7. Koppelman, S. J., Hackeng, T. M., Sixma, J. J., and Bouma, B. N. (1995) Blood 86, 1062-1071
8. Heeb, M. J., Koenen, R. R., Fernandez, J. A., and Hackeng, T. M. (2004) J. Thromb. Haemostasis 2, 1766-1773
9. Webb, J. H., Blom, A. M., and Dahlbäck, B. (2002) J. Immunol. 169, 2580-2586
10. Kask, L., Trouw, L. A., Dahlbäck, B., and Blom, A. M. (2004) J. Biol. Chem. 279, 23869-23873
11. Schwarz, H. P., Fischer, M., Hopmeier, P., Batard, M. A., and Griffin, J. H. (1984) Blood 64, 1297-1300
12. Engesser, L., Broekmans, A. W., Briet, E., Brommer, E. J., and Bertina, R. M. (1987) Ann. Intern. Med. 106, 677-682
13. Makris, M., Leach, M., Beauchamp, N. J., Daly, M. E., Cooper, P. C., Hampton, K. K., Bayliss, P., Peake, I. R., Miller, G. J., and Preston, F. E. (2000) Blood 95, 1935-1941
14. Gandrille, S., Borgel, D., Ireland, H., Lane, D. A., Simmonds, R., Reitsma, P. H., Mannhalter, C., Pabinger, I., Saito, H., Suzuki, K., Formstone, C., Cooper, D. N., Espinosa, Y., Sala, N., Bernardi, F., and Aiach, M. (1997) Thromb. Haemostasis 77, 1201-1214
15. Gandrille, S., Borgel, D., Sala, N., Espinosa-Parrilla, Y., Simmonds, R., Rezende, S., Lind, B., Mannhalter, C., Pabinger, I., Reitsma, P. H., Formstone, C., Cooper, D. N., Saito, H., Suzuki, K., Bernardi, F., and Aiach, M. (2000) Thromb. Haemostasis 84, 918
16. D'Angelo, A., Vigano-D'Angelo, S., Esmon, C. T., and Comp, P. C. (1988) J. Clin. Investig. 81, 1445-1454
17. Fair, D. S., and Marlar, R. A. (1986) Blood 67, 64-70
18. Ogura, M., Tanabe, N., Nishioka, J., Suzuki, K., and Saito, H. (1987) Blood 70, 301-306
19. Fair, D. S., Marlar, R. A., and Levin, E. G. (1986) Blood 67, 1168-1171
20. Stitt, T. N., Conn, G., Gore, M., Lai, C., Bruno, J., Radziejewski, C., Mattsson, K., Fisher, J., Gies, D. R., and Jones, P. F. (1995) Cell 80, 661-670
21. Malm, J., He, X. H., Bjartell, A., Shen, L., Abrahamsson, P. A., and Dahlbäck, B. (1994) Biochem. J. 302, 845-850
22. Maillard, C., Berruyer, M., Serre, C. M., Dechavanne, M., and Delmas, P. D. (1992) Endocrinology 130, 1599-1604
23. Schwarz, H. P., Heeb, M. J., Wencel-Drake, J. D., and Griffin, J. H. (1985) Blood 66, 1452-1455
24. Stern, D., Brett, J., Harris, K., and Nawroth, P. (1986) J. Cell Biol. 102, 1971-1978
25. Benzakour, O., and Kanthou, C. (2000) Blood 95, 2008-2014
26. Dahlbäck, B., and Stenflo, J. (1981) Proc. Natl. Acad. Sci. U. S. A 78, 2512-2516
27. Dahlbäck, B. (1986) J. Biol. Chem. 261, 12022-12027
28. Griffin, J. H., Gruber, A., and Fernandez, J. A. (1992) Blood 79, 3203-3211
29. Schmidel, D. K., Tatro, A. V., Phelps, L. G., Tomczak, J. A., and Long, G. L. (1990) Biochemistry 29, 7845-7852
30. Ploos van Amstel, H. K., Reitsma, P. H., van der Logt, C. P., and Bertina, R. M. (1990) Biochemistry 29, 7853-7861
31. Edenbrandt, C. M., Lundwall, A., Wydro, R., and Stenflo, J. (1990) Biochemistry 29, 7861-7868
32. De Wolf, C. J. F., Cupers, R. M., Bertina, R. M., and Vos, H. L. (2005) J. Thromb. Haemostasis 3, 410-412
33. Tatewaki, H., Tsuda, H., Kanaji, T., Yokoyama, K., and Hamasaki, N. (2003) Thromb. Haemostasis 90, 1029-1039
34. Udvadia, A. J., Rogers, K. T., Higgins, P. D., Murata, Y., Martin, K. H., Humphrey, P. A., and Horowitz, J. M. (1993) Proc. Natl. Acad. Sci. U. S. A 90, 3265-3269
35. Udvadia, A. J., Templeton, D. J., and Horowitz, J. M. (1995) Proc. Natl. Acad. Sci. U. S. A 92, 3953-3957
36. Lai, E., Prezioso, V. R., Tao, W. F., Chen, W. S., and Darnell, J. E., Jr. (1991) Genes Dev. 5, 416-427
37. Deutz-Terlouw, P. P., Ballering, L., van Wijngaarden, A., and Bertina, R. M. (1990) Clin. Chim. Acta 186, 321-324
38. Dignam, J. D., Lebovitz, R. M., and Roeder, R. G. (1983) Nucleic Acids Res. 11, 1475-1489
39. Quandt, K., Frech, K., Karas, H., Wingender, E., and Werner, T. (1995) Nucleic Acids Res. 23, 4878-4884
40. Mayor, C., Brudno, M., Schwartz, J. R., Poliakov, A., Rubin, E. M., Frazer, K. A., Pachter, L. S., and Dubchak, I. (2000) Bioinformatics (Oxf.) 16, 1046-1047
41. Loots, G. G., Ovcharenko, I., Pachter, L., Dubchak, I., and Rubin, E. M. (2002) Genome Res. 12, 832-839
42. Suske, G. (1999) Gene (Amst.) 238, 291-300
43. Sapetschnig, A., Koch, F., Rischitor, G., Mennenga, T., and Suske, G. (2004) J. Biol. Chem. 279, 42095-42105
44. Dykes, A. C., Walker, I. D., McMahon, A. D., Islam, S. I., and Tait, R. C. (2001) Br. J. Haematol. 113, 636-641
45. Beauchamp, N. J., Dykes, A. C., Parikh, N., Campbell, T. R., and Daly, M. E. (2004) Br. J. Haematol. 125, 647-654
46. Koster, T., Rosendaal, F. R., Briet, E., van der Meer, F. J., Colly, L. P., Trienekens, P. H., Poort, S. R., Reitsma, P. H., and Vandenbroucke, J. P. (1995) Blood 85, 2756-2761
47. Comp, P. C., Thurnau, G. R., Welsh, J., and Esmon, C. T. (1986) Blood 68, 881-885
48. Tans, G., Curvers, J., Middeldorp, S., Thomassen, M. C., Meijers, J. C., Prins, M. H., Bouma, B. N., Buller, H. R., and Rosing, J. (2000) Thromb. Haemostasis 84, 15-21
49. Vigano-D'Angelo, S., D'Angelo, A., Kaufman, C. E., Jr., Sholer, C., Esmon, C. T., and Comp, P. C. (1987) Ann. Intern. Med. 107, 42-47
50. Kemkes-Matthes, B. (1992) Clin. Investig. 70, 529-534
51. Macleod, D., Charlton, J., Mullins, J., and Bird, A. P. (1994) Genes Dev. 8, 2282-2292
52. Mummaneni, P., Yates, P., Simpson, J., Rose, J., and Turker, M. S. (1998) Nucleic Acids Res. 26, 5163-5169
53. Boekhoudt, G. H., Guo, Z., Beresford, G. W., and Boss, J. M. (2003) J. Immunol. 170, 4139-4147
54. Stirzaker, C., Song, J. Z., Davidson, B., and Clark, S. J. (2004) Cancer Res. 64, 3871-3877
55. Habener, J. F. (1990) Mol. Endocrinol. 4, 1087-1094
56. Lalli, E., and Sassone-Corsi, P. (1994) J. Biol. Chem. 269, 17359-17362
57. Mantovani, R. (1999) Gene (Amst.) 239, 15-27
58. Peng, Y., and Jahroudi, N. (2002) Blood 99, 2408-2417