Chronic L-arginine administration increases oxidative and nitrosative stress in rat hyperoxaluric kidneys and excessive crystal deposition

American Journal of Physiology - Renal Physiology

Volumn 295, Issue 2, 2008, Pages

  Huang, Ho Shiang ^a   Ma, Ming Chieh ^b   Chen, Jun ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b FU JEN CATHOLIC UNIVERSITY   (Taiwan)

Author keywords

Hyperoxaluria; NAD(P)H oxidase; Nephrolithiasis; Nitric oxide synthase

Indexed keywords

ARGININE; CALCIUM OXALATE; INDUCIBLE NITRIC OXIDE SYNTHASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENZYME INHIBITOR; HYDROXYPROLINE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYSTALLIZATION; HYPEROXALURIA; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; URINALYSIS; ANIMAL; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; KIDNEY; METABOLISM; WISTAR RAT;

ANIMALS; ARGININE; CALCIUM OXALATE; CRYSTALLIZATION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HYDROXYPROLINE; HYPEROXALURIA; KIDNEY; MALE; NADPH OXIDASE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

EID: 52449084508     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00405.2007     Document Type: Article

References (38)

1. Barocelli E, Ballabeni V, Ghizzardi P, Cattaruzza F, Bertoni S, Lagrasta CA, Impicciatore M. The selective inhibition of inducible nitric oxide synthase prevents intestinal ischemia-reperfusion injury in mice. Nitric Oxide 14: 212-218, 2006.
2. Baylis C, Bloch J. Nitric oxide in renal physiology and pathophysiology. Nephrol Dial Transplant 11: 1955-1957, 1996.
3. Böger RH, Bode-Böger SM, Kienke S, Stan AC, Nafe R, Frolich JC. Dietary L-arginine decreases myointimal cell proliferation and vascular monocyte accumulation in cholesterol-fed rabbits. Atherosclerosis 36: 67-77, 1998.
4. Chatterjee PK, Cuzzicrea S, Brown PAJ, Zachorowski K, Stewart KN, Mota-Filipe H, Thiemermann C. Tempol, a membrane permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat. Kidney Int 58: 658-673, 2000.
5. Chen C, Mitchell KD, Navar LG. Role of endothelial derived nitric oxide in the renal hemodynamic response to amino acid infusion. Am J Physiol Regul Integr Comp Physiol 263: R510-R516, 1992.
6. Chen CF, Chien SU, Wu MS. Renal response during acute unilateral ureteral obstruction in rats. Neurourol Urodynam 20: 125-137, 2001.
7. Gabbai FB. Effects of nitric oxide synthase blockers on renal function. Nephrol Dial Transplant 16, Suppl 1: 10-13, 2001.
8. Gabbai FB, Blantz RC. Role of nitric oxide in renal hemodynamics. Semin Nephro 19: 242-250, 1999.
9. Gologorsky MS, Noiri E. Duality of nitric oxide in acute renal injury. Semin Nephro 19: 263-271, 1999.
10. Haruna Y, Morita Y, Komai N, Yada T, Satoh M, Fox DA, Kashinhara N. Endothelial dysfunction in rat adjuvant-induced arthritis: vascular superoxide anion production by NAD(P)H oxidase and uncoupled endothelial nitric oxide synthase. Arthritis Rheum 54: 1847-1855, 2006.
11. Heeringa P, van Goor H, Moshage H, Klok PA, Huitema MG, de Jager A, Schep AJ, Kallenberg CG. Expression of iNOS, eNOS, and peroxynitrite- modified proteins in experimental anti-myeloperoxidase associated crescentic glomerulonephritis. Kidney Int 53: 382-393, 1998.
12. Hessel E, Aberland A, MBller M, Lerche D, Schimke I. Oxygen radical generation of neutrophils: a reason for oxidative stress during marathon running? Clinica Chimica Acta 298: 145-156, 2000.
13. Huang HS, Chen CF, Chien CT, Chen J. Changes in the oxidant-antioxidant balance in the kidney of rats with nephrolithiasis induced by ethylene glycol. J Urol 167: 2584-2593, 2002.
14. Huang HS, Chen J, Chen CF, Ma MC. Vitamin E attenuates crystal formation in rat kidneys: Roles of renal tubular cell death an crystallization inhibitors. Kidney Int 70: 699-710, 2006.
15. Huang HS, Ma MC, Chen CF, Chen J. Lipid peroxidation and its correlations with urinary levels of oxalate, citric acid, and osteopontin in patients with renal calcium oxalate stones. Urology 62: 1123-1128, 2003.
16. Huang HS, Ma MC, Chen J, Chen CF. Changes in renal hemodynamics and urodynamics in rats with chronic hyperoxaluria and after acute oxalate infusion: role of free radicals. Neurourol Urodynam 22: 176-182, 2003.
17. Huang HS, Ma MC, Chen CF, Chen J. Changes in nitric oxide production in the rats kidney due to CaOx nephrolithiasis. Neurourol Urodynam 25: 252-258, 2006.
18. Jia YT, Ma B, Wei W, Xu Y, Wang Y, Aang HT, Xai ZF. Sustained activation of nuclear factor-EB by reactive oxygen species is involved in the pathogenesis of stress-induced gastric damage in rats. Crit Care Med 35: 1582-1591, 2007.
19. Khan SR, Glenton PA, Byer KJ. Modeling of hyperoxaluric calcium oxalate nephrolithiasis: Experimental induction of hyperoxaluria by hydroxyl-L-proline. Kidney Int 70: 914-923, 2006.
20. Khan SR, Shevock PN, Hackett R. Urinary enzymes and CaOx urolithiasis. J Urol 142: 846-949, 1989.
21. Kitiyakara C, Chabrashvili T, Chen Y, Blau J, Karber A, alsam S, Welch WJ, Wicox CS. Salt intake, oxidative stress and renal expression of NADPH oxidase and superoxide dismutase. J Am Soc Nephrol 14: 2775-2782, 2003.
22. Landmesser U, Dikalov S, Price SR, McClann L, Fukai T, Holland SM, Mitch WE, Harrison DG. Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. J Clin Invest 111: 1201-1209, 2003.
23. Laursen JB, Somers M, Kurz S, McClann L, wamholtz A, Freeman BA, Rarpey M, Fukai T, Harrison DG. Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin. Circulation 103: 1282-1288, 2001.
24. Lubec B, Hayn M, Kitzmuller E, Vierhapper H, Lubec G. L-Arginine reduces lipid peroxidation in patients with diabetes mellitus. Free Radic Biol Med 22: 355-357, 1997.
25. Meimaridou E, Lobos E, Hothersall JS. Renal oxidative vulnerability due to changes in mitochondrial-glutathione and energy homeostasis in a rat model of calcium oxalate urolithiasis. Am J Physiol Renal Physiol 291: F731-F740, 2006.
26. Miller MJ, Sadowska-Krowicka H, Chotinaruemol S, Kakkis JL, Clark DA. Amelioration of chronic ileitis by nitric oxide synthase inhibition. J Pharmacol Exp Ther 264: 11-16, 1993.
27. Mollnau H, Wendt M, Szocs K, Lasegue B, Schilz E, Tsilimingas N, Watter U, Forstermann U, Meinertz T, Griendling K, Munzel T. Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling. Circ Res 90: E58-E65, 2002.
28. Peresleni T, Noiri E, Bahou WF, Goligorsky MS. Anti-sense oligode-oxynucleotides to inducible NO synthase rescue epithelial cells from oxidative stress injury. Am J Physiol Renal Fluid Electrolyte Physiol 270: F971-F977, 1996.
29. Pragasam V, Kalaiselvi P, Subsashini B, Sumitra K, Varalakshmi P. Structural and functional modification of THP on nitration: comparison with stone formers THP. Nephron Physiol 99: 28-34, 2005.
30. Pragasam V, Kalaiselvi P, Subashini B, Sumitra K, Varalakshmi P. Counteraction of oxalate induced nitrosative stress by supplementation of L-arginine, a potent antilithic agent. Clin Chim Acta 354: 159-166, 2005.
31. Reyes AA, Karl IE, Klahr S. Role of arginine in health and disease. Am J Physiol Renal Fluid Electrolyte Physiol 267: F331-F346, 1994.
32. Reyes AA, Porras BH, Chasalow FI, Klahr S. L-Arginine decreases the infiltration of the kidney by macrophages in obstructive nephropathy and puromycin-induced nephrosis. Kidney Int 45: 1346-1354, 1994.
33. Selvam R. Calcium oxalate stone disease: role of lipid peroxidation and antioxidants. Urol Res 30: 35-47, 2002.
34. Simonet S, Rupin A, Badier-Commander C, Coumailleau S, Behr-Roussel D, Verbeuren TJ. Evidence for superoxide anion generation in aortas of cholesterol-fed rabbits treated with L-arginine. Eur J Pharmacol 492: 211-216, 2004.
35. Tiselius HG, Ribeiro R, Ferraz N, Heilberg IP. An approximate estimate of the ion-activity product of calcium oxalate in rat urine. Urol Res 31: 410-413, 2003.
36. Umekawa T, Byer K, Uemura H, Khan SR. Diphenyleneiodium (DPI) reduces oxalate ion- and calcium oxalate monohydrate and brushite crystal-induced upregulation of MCP-1 in NRK 52E cells. Nephrol Dial Transplant 20: 870-878, 2005.
37. Ushio-Fukai M, Tang Y, Fukai T, Diklov SI, Ma Y, Fujimoto M, Quinn MT, Pagano PJ, Johnson C, Alexandr RW. Novel role of gp91phos-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis. Circ Res 91: 1160-1167, 2002.
38. Zou AP, Cowley W. Role of nitric oxide in the control of renal function and salt sensitivity. Curr Hypertens Res 1: 178-186, 1999.