Role of nitric oxide in the control of renal function and salt sensitivity

Current Hypertension Reports

Volumn 1, Issue 2, 1999, Pages 178-186

  Zou, Ai Ping ^a   Cowley Jr , Allen W ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL; DAHL SALT SENSITIVE RAT; ELECTROLYTE BALANCE; HUMAN; HYPERTENSION; KIDNEY; KIDNEY CIRCULATION; KIDNEY FUNCTION TEST; NATRIURESIS; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; REVIEW; SALT INTAKE;

ANIMALS; HUMANS; HYPERTENSION; KIDNEY; KIDNEY FUNCTION TESTS; NATRIURESIS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; RATS; RATS, INBRED DAHL; RENAL CIRCULATION; SODIUM CHLORIDE, DIETARY; WATER-ELECTROLYTE BALANCE;

EID: 0033108016     PISSN: 15226417     EISSN: 15343111     Source Type: Journal    
DOI: 10.1007/s11906-999-0016-7     Document Type: Article

References (60)

1. Kone BC, Baylis C: Biosynthesis and homeostatic roles of nitric oxide in the normal kidney. Am J Physiol 1997, 272:F561-F578.
2. Stamler JS, Singel DJ, Loscalzo J: Biochemistry of nitric oxide and its redox-activated forms. Science. 1992, 258:1989-1902.
3. Gross SS, Wolin MS: Nitric Oxide: Pathophysiological mechanism. Ann Rev Physiol 1995, 57:737-769.
4. Schnackenberg C, Patel AR, Kirchner KA, et al.: Nitric oxide, the kidney and hypertension. Clin Exp Pharmacol Physiol 1997, 24:600-606.
5. Bredt DS, Snyder SH. Nitric oxide: a physiologic messenger molecules. Ann Rev Biochem 1994, 63:175-195.
6. Fukuto JM, Wallace GC, Hszieh R, et al.: Chemical oxidation of N-hydroxyguanidine compounds: release of nitric oxide, nitroxyl and possible relationship to the mechanism of biological nitric oxide generation. Biochem Pharmacol 1992, 43:607-613.
7. Mayer B, John M, Heinzel B, et al.: Brain nitric oxide synthesis is a biopterin- and flavin-containing multi-functional oxidoreductase. FEBS Lett 1991, 288:187-191.
8. Venema RC, Sayegh HS, Kent JD, Harrison DG. Identification, characterization, and comparison of the calmodulin binding domains of the endothelial and inducible nitric oxide synthases. J Biol Chem 1996, 271:6435-6440.
9. Bachmann S, Mundel P. Nitric oxide in the kidney: synthesis, localization, and function. Am J Kidney Dis 1994, 24:112-129.
10. Zou A-P, Cowley AW Jr. Nitric oxide in renal cortex and medulla: an in vivo microdialysis study. Hypertension. 1997;29:194-198.
11. Zou AP, Wu F, Cowley AW Jr: Protective effect of angiotensin II-induced increase in nitric oxide in the renal medullary circulation. Hypertension 1998, 31:271-276.
12. Mattson DL, Maeda CY, Bachman TD, et al.: Inducible nitric oxide synthase and blood pressure. Hypertension. 1998;31:15-20. This paper defined the role of renal medullary iNOS activity in the control of arterial blood pressure. Physioloic and biochemical approaches were used to determine the effect of iNOS activity on renal sodium and water excretion. Tubular regulatory effect, but not medullary blood flow, is suggested as being responsible for sodium retention and development of hypertension induced by iNOS inhibiton. The data provide the first evidence that renal medullary iNOS is of importance in control of arterial blood pressure.
13. Hayakawa H tand Raji L. Nitric oxide synthase activity and renal injury in genetic hypertension. Hypertension 1998, 31:266-270. This study analyzed the NOS activity in different hypertensive rats such as SHR and Dahl S rats. The data indicates that a NOS deficit is present in the renal medulla in Dahl S rats. This deficit of NOS activity may be a pathogenic factor in salt-sensitive hypertension.
14. Mattson DL, Higgins D: Influence of dietary sodium intake on renal medullary nitric oxide synthesis. Hypertension 1996, 27:688-692.
15. Wu F, Cowley AW Jr, Mattson DL: Nitric oxide synthase (NOS) activity in microdissected segments of the Sprague Dawley rat kidney. FASEB J 1998, 12:A53.
16. Harrison DG, Sayegh H, Ohara Y, et al.: Regulation of expression of the endothelial cell nitric oxide synthase. Clin Exp Pharmacol Physiol 1996, 23:251-255.
17. Foestermann U, Kleinert H: Nitric oxide synthase: expression and expressional control of the three isoforms. Naunyn-Schmiedberg's Arch Pharmacol 1995, 352:351-364.
18. Zou AP, Su N, Park F, et al.: Expression of hypoxia-inducible factor-1 in renal cortical and medulla tissue and dissected tubules in rats. FASEB J 1998, 12:A684.
19. Deng AY, Baylis C: Locally produced EDRF controls preglomerular resistance and ultrafiltration coefficient. Am J Physiol 1993, 264:F212-F215.
20. Imig JD, Roman RJ: Nitric oxide modulates vascular tone in preglomerular arterioles. Hypertension 1992, 19:770-774.
21. Ito S, Airma S, Ren YL, et al.: Endothelium-derived relaxing factor/nitric oxide modulates angiotensin II action in the isolated microperfused rabbit afferent arterioles but not efferent arterioels. J Clin Invest 1993, 91:2011-2019.
22. Hoffend J, Cavarape A, Endlich K, et al.: Influence of endotheliumderived relaxing factor on renal microvessels and pressuredependent vasodilation. Am J Physiol 1993, 265:F285-F292.
23. Ohishi K, Carmines PK, Inscho EW, et al.: EDRF-angiotensin II interactions in rat juxtamedullary afferent and efferent arterioles. Am J Physiol 1992, 32:F900-F906.
24. Wilcox CS, Welch WJ, Murad F, et al.: Nitric oxide synthase in macula densa regulates glomerular capillary pressure. Proc Natl Acad Sci USA. 1992, 89:11993-11997.
25. Welch WJ, Wilcox CS: Role of nitric oxide in tubuloglomerular feedback: effect of dietary salt. Clinic Exp Pharmacol Physiol 1997, 24:582-586.
26. Welch WJ, Wilcox CS: Macula densa arginine delivery and uptake in the rat regulate glomerular capillary pressure: effect of salt intake. J Clin Invest 1997, 100:2235-2242. This paper demonstrated that alteration of tubuloglomerular feedback response is associated with the L-arginine transporter, y+ system in the macula densa area. The changes in L-argininer transport may represent a new adaptive mechanism to salt intake and play an important role in the control of renal sodium excretion.
27. Zatz R, Nucci GD: Effects of acute nitric oxide inhibition on rat glomerular microcirculation. Am J Physiol 1991, 261:F360-F362.
28. Raij L, Baylis C: Glomerular action of nitric oxide. Kidney Int 1995, 48:20-32.
29. Shultz PJ, Schorer AE, Raij L. Effects of endothelium-derived relaxing factor and nitric oxide on rat mesangial cells. Am J Physiol 1990, 258:F162-F167.
30. Romero JC, Lahera V, Salam MG, et al.: Role of the endotheliumdependent relaxing factor nitric oxide on renal function. J Am Soc Nephrol 1992, 2:1371-1387.
31. Radermacher J, Klanke B, Schurk HJ, et al.: Importance of EDRF/NO for glomerular and tubular function: studies in the isolated perfused rat kidney. Kidney Int 1992, 41:1549-1559.
32. Stoors BA, Garcia NH, Garvin JL: Nitric oxide inhibits sodium reabsorption in the isolated perfused cortical collecting duct. J am Soc Nephrol 1995, 6:89-94.
33. Mckee M, Scavone C, Nathanson JA.: Nitric oxide, cGMP, and hormone regulation of active sodium transport. Proc Natl Acad Sci USA 1994, 91:12056-12060.
34. Roczniak A, Burns KD: Nitric oxide stimulates guanylate cyclase and regulates sodium transport in rabbit proximal tubule. Am J Physiol 1996, 270:F106-F115.
35. Plato CF, Wang D, Garvin JL: Endogenous NO inhibits chloride flux in the thick ascending limb. Hypertension 1998, 32:616.
36. Kone BC, Higham SC: Autocrine regulation of mTAL active sodium reabsorption by tonically expressed inducible nitric oxide synthase (iNOS). J Am Soc Nephrol 1996, 7:1283.
37. Cowley AW Jr: Role of the renal medulla in volume and arterial pressure regulation. Am J Physiol 1997, 273:R1-R15.
38. Mattson DL, Roman RJ, Cowley AW Jr: Role of nitric oxide in renal papillary blood flow and sodium excretion. Hypertension 1992, 19:766-769.
39. Salom MG, Lahera V, Guardiola FM, et al.: Blockade of pressure natriuresis induced by inhibition of renal synthesis of nitric oxide in dogs. Am J Physiol 1992, 262:F718-F722.
40. Guarasci GR, Kline RL: Pressure natriuresis following acute and chronic inhibition of nitric oxide synthase in rats. Am J Physiol 1996, 270:R469-R478.
41. Majid DS, Navar LG: Nitric oxide in the mediation of pressure natriuresis. Clin Exp Pharmacol Physiol 1997, 24:595-599.
42. Ikeda Y, Saito K, Kim JI, et al.: Nitric oxide synthase isoform activities in kidney of Dahl salt-sensitive rats. Hypertension 1995, 26:1030-1034.
43. Huang PL, Huang Z, Mashimo H, et al.: Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 1995, 377:239-242.
44. Baylis C, Mitruka B, Deng A: Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage. J Clin Invest 1992, 90:278-281.
45. Pollock DM, Polakowski JS, Divish BJ, et al.: Angiotensin blockade reverses hypertension during long-term nitric oxide synthase inhibtion. Hypertension 1993, 231:660-666.
46. Mattson DL, Lu S, Nakanishi K, et al.: Effect of chronic renal medullary nitric oxide inhibition on blood pressure. Am J Physiol 1994, 266:H1918-H1926.
47. Baylis C, Harvey J, Engels K: Acute nitric oxide blockade amplifies the renal vasoconstrictor actions of angiotensin II. J Am Soc Nephrol 1994, 5:211-214.
48. Deng X, Welch WJ, Wilcox CS: Role of nitric oxide in short term and prolonged effects of angiotensin II on renal hemodynamics. Hypertension 1996, 27:1173-1179.
49. Du ZY, Dusting GJ, Woodman OL: Inhibition of nitric oxide synthase specifically enhances adrenergic vasoconstriction in rabbits. Clin Exp Pharmacol Physiol 1992, 19:523-530.
50. Parekh N, Dobrowolski L, Zou A-P, et al.: Nitric oxide modulates angiotensin II- and norepinephrine-dependent vasoconstriction in rat kidney. Am J Physiol 1996, 270:R630-R635.
51. 2 receptors, which may be important to the control of renal function and arterial blood pressure.
52. Hennington BS, Zhang H, Miller MT, et al.: Angiotensin II stimulates synthesis of endothelial nitric oxide synthase. Hypertension 1998, 31:283-288. Angiotensin II-induced acute and chronic adaptive changes in eNOS in response to elevation of angiotensin II were determined. This is the first study indicating the stimulation of mRNA and protein of eNOS by short-term or long-term infusion of angiotensin II. The results suggest that upregulation of eNOS plays an important role in modulating angiotensin II-induced vasoconstriction.
53. Szentivanyi M, Cowley AW Jr: Chronic angiotensin II-nitric oxide interactions in the renal medulla. Hypertension 1998, 32:601.
54. Shultz PJ, Tolins JP: Adaptation to increased dietary salt intake in the rat. Role of endogenous nitric oxide. J Clin Invest 1993, 91:642-650.
55. Tolins JP, Shultz PJ. Endogenous nitric oxide synthesis determines sensitivity to the pressor effect of salt. Kidney Int 1994, 46:230-236.
56. Yamada SS, Sassaki AL, Fujihara CK, et al.: Effect of salt intake and inhibitor dose on arterial hypertension and renal injury induced by chronic nitric oxide blockade. Hypertension 1996, 27:1165-1172.
57. Chen PY, Sanders PW. Role of nitric oxide synthase in salt-sensitive hypertension in Dahl/Rapp rats. Hypertension 1993, 22:812-818.
58. Hu L, Manning RD Jr: Role of nitric oxide in regulation of long-term pressure-natriuresis relationship in Dahl rats. Am J Physiol 1995, 268:H2375-H2383.
59. Patel A, Layne S, Watts D, et al.: L-arginine administration normalizes pressure natriuresis in hypertensive Dahl rats. Hypertension 1993, 22:863-869.
60. Miyata N, Zou AP, Mattson DL, et al.: Renal medullary interstitial infusion of L-arginine prevents hypertension in Dahl salt-sensitive rats. Am J Physiol 1998, 275:R1667-R1673.