-
1
-
-
0344760902
-
-
Panel on Antiretroviral Guidelines for Adult and Adolescents, Available from:, Last accessed 16 February 2008
-
Panel on Antiretroviral Guidelines for Adult and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services, 2008. Available from: http://www.aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf [Last accessed 16 February 2008]
-
(2008)
Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents
-
-
-
2
-
-
52349110591
-
-
FDA approves first drug in new class of HIV treatments for HIV infected adults and children with advanced disease, 2003. Available from:, Last accessed 19 February 2008
-
FDA approves first drug in new class of HIV treatments for HIV infected adults and children with advanced disease, 2003. Available from: http://www.fda.gov/bbs/topics/NEWS/2003/NEW00879.html [Last accessed 19 February 2008]
-
-
-
-
3
-
-
52349108664
-
-
FDA approves new therapy for HIV patients with advanced disease. FDA News. 2005. Available from: http://www.fda.gov/bbs/topics/NEWS/2005/ NEW01189.html [Last accessed 19 February 2008]
-
FDA approves new therapy for HIV patients with advanced disease. FDA News. 2005. Available from: http://www.fda.gov/bbs/topics/NEWS/2005/ NEW01189.html [Last accessed 19 February 2008]
-
-
-
-
4
-
-
52349109312
-
-
FDA approves new HIV drug: raltegravir tablets used in combination with other antiretroviral agents. FDA News. 2006. Available from: http://www.fda.gov/bbs/topics/NEWS/2007/NEW01726.html [Last accessed 19 February 2008]
-
FDA approves new HIV drug: raltegravir tablets used in combination with other antiretroviral agents. FDA News. 2006. Available from: http://www.fda.gov/bbs/topics/NEWS/2007/NEW01726.html [Last accessed 19 February 2008]
-
-
-
-
5
-
-
52349090281
-
-
FDA approves new HIV treatment for patients who do not respond to existing drugs. FDA News. 2006. Available from: http://www.fda.gov/bbs/ topics/NEWS/2006/NEW01395.html [Last accessed February 19 2008]
-
FDA approves new HIV treatment for patients who do not respond to existing drugs. FDA News. 2006. Available from: http://www.fda.gov/bbs/ topics/NEWS/2006/NEW01395.html [Last accessed February 19 2008]
-
-
-
-
6
-
-
52349103721
-
-
FDA approves novel antiretroviral drug. FDA News. 2007. Available from: http://www.fda.gov/bbs/topics/NEWS/2007/NEW01677.html [Last accessed February 19 2008]
-
FDA approves novel antiretroviral drug. FDA News. 2007. Available from: http://www.fda.gov/bbs/topics/NEWS/2007/NEW01677.html [Last accessed February 19 2008]
-
-
-
-
7
-
-
52349122221
-
-
FDA approves new HIV drug after priority review: etravirine tablets used in combination with other antiretroviral agents. FDA News. 2008. Available from: http://www.fda.gov/bbs/topics/NEWS/2008/NEW01783.html [Last accessed 19 February 2008]
-
FDA approves new HIV drug after priority review: etravirine tablets used in combination with other antiretroviral agents. FDA News. 2008. Available from: http://www.fda.gov/bbs/topics/NEWS/2008/NEW01783.html [Last accessed 19 February 2008]
-
-
-
-
9
-
-
0038576281
-
Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America
-
Lalezari JP, Henry K, O'Hearn M, et al. Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America. N Engl J Med 2003;348(22):2175-85
-
(2003)
N Engl J Med
, vol.348
, Issue.22
, pp. 2175-2185
-
-
Lalezari, J.P.1
Henry, K.2
O'Hearn, M.3
-
10
-
-
0037849954
-
Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia
-
Lazzarin A, Clotet B, Cooper D, et al. Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia. N Engl J Med 2003;348(22):2186-95
-
(2003)
N Engl J Med
, vol.348
, Issue.22
, pp. 2186-2195
-
-
Lazzarin, A.1
Clotet, B.2
Cooper, D.3
-
11
-
-
33746576313
-
Durable efficacy of tipranavir-ritonavir in combination with an optimised background regimen of antiretroviral drugs for treatment-experienced HIV-1-infected patients at 48 weeks in the randomized evaluation of strategic intervention in multi-drug reSistant patients with tipranavir (RESIST) studies: An analysis of combined data from two randomised open-label trials
-
Hicks CB, Cahn P, Cooper DA, et al. Durable efficacy of tipranavir-ritonavir in combination with an optimised background regimen of antiretroviral drugs for treatment-experienced HIV-1-infected patients at 48 weeks in the randomized evaluation of strategic intervention in multi-drug reSistant patients with tipranavir (RESIST) studies: an analysis of combined data from two randomised open-label trials. Lancet 2006;368(9534):466-75
-
(2006)
Lancet
, vol.368
, Issue.9534
, pp. 466-475
-
-
Hicks, C.B.1
Cahn, P.2
Cooper, D.A.3
-
12
-
-
34047207229
-
Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2: A pooled subgroup analysis of data from two randomised trials
-
Clotet B, Bellos N, Molina JM, et al. Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2: a pooled subgroup analysis of data from two randomised trials. Lancet 2007;369(9568):1169-78
-
(2007)
Lancet
, vol.369
, Issue.9568
, pp. 1169-1178
-
-
Clotet, B.1
Bellos, N.2
Molina, J.M.3
-
13
-
-
43749121302
-
DUET-1: Week 48 results of a phase III randomized double-blind trial to evaluate the efficacy and safety of etravirine (ETR; TMC125) versus placebo in 612 treatment-experienced HIV-1-infected patients
-
abstract 790, 3-6 February, Boston, Massachusetts, USA
-
Haubrich R, Cahn P, Grinsztejn B, et al. DUET-1: week 48 results of a phase III randomized double-blind trial to evaluate the efficacy and safety of etravirine (ETR; TMC125) versus placebo in 612 treatment-experienced HIV-1-infected patients [abstract 790]. Proceedings of the 15th Conference on Retroviruses and Opportunistic Infections (CROI); 3-6 February 2008; Boston, Massachusetts, USA
-
(2008)
Proceedings of the 15th Conference on Retroviruses and Opportunistic Infections (CROI)
-
-
Haubrich, R.1
Cahn, P.2
Grinsztejn, B.3
-
14
-
-
43749103048
-
DUET-2: Week-48 results of a phase III randomized double-blind trial to evaluate the efficacy and safety of TMC125 vs. placebo in 591 treatment-experienced HIV-1-infected patients
-
abstract 791, 3-6 February, Boston, Massachusetts, USA
-
Johnson M, Campbell T, Clotet B, et al. DUET-2: week-48 results of a phase III randomized double-blind trial to evaluate the efficacy and safety of TMC125 vs. placebo in 591 treatment-experienced HIV-1-infected patients [abstract 791]. Proceedings of the 15th Conference on Retroviruses and Opportunistic Infections (CROI). 3-6 February 2008; Boston, Massachusetts, USA
-
(2008)
Proceedings of the 15th Conference on Retroviruses and Opportunistic Infections (CROI)
-
-
Johnson, M.1
Campbell, T.2
Clotet, B.3
-
15
-
-
43749098454
-
48-Week results from BENCHMRK-1, a phase III study of raltegravir (RAL) in patients failing antiretroviral therapy (ART) with triple-class resistant HIV-1
-
abstract 788, 3-6 February, Boston, Massachusetts, USA
-
Cooper DA, Gatell J, Rockstroh J, et al. 48-Week results from BENCHMRK-1, a phase III study of raltegravir (RAL) in patients failing antiretroviral therapy (ART) with triple-class resistant HIV-1 [abstract 788]. 15th Conference on Retroviruses and Opportunistic Infections (CROI); 3-6 February 2008; Boston, Massachusetts, USA
-
(2008)
15th Conference on Retroviruses and Opportunistic Infections (CROI)
-
-
Cooper, D.A.1
Gatell, J.2
Rockstroh, J.3
-
16
-
-
43749084994
-
48-Week results from BENCHMRK-2, a phase III study of raltegravir in patients failing ART with triple-class resistant HIV
-
abstract 789, 3-6 February, Boston, Massachusetts, USA
-
Steigbigel R, Kumar P, Eton J, et al. 48-Week results from BENCHMRK-2, a phase III study of raltegravir in patients failing ART with triple-class resistant HIV [abstract 789]. Proceedings of the 15th Conference on Retroviruses and Opportunistic Infections (CROI); 3-6 February 2008; Boston, Massachusetts, USA
-
(2008)
Proceedings of the 15th Conference on Retroviruses and Opportunistic Infections (CROI)
-
-
Steigbigel, R.1
Kumar, P.2
Eton, J.3
-
17
-
-
35048870707
-
Efficacy and safety of maraviroc in antiretroviral experienced patients infected with CCR5 tropic HIV-1: 48 week results of Motivate 1 [presentation number H-718a]
-
September, Chicago, Illinois, USA
-
Lalezari J, Goodrich J, DeJesus E, et al. Efficacy and safety of maraviroc in antiretroviral experienced patients infected with CCR5 tropic HIV-1: 48 week results of Motivate 1 [presentation number H-718a]. 47th ICAAC; 17-20 September 2007; Chicago, Illinois, USA
-
(2007)
47th ICAAC; 17-20
-
-
Lalezari, J.1
Goodrich, J.2
DeJesus, E.3
-
18
-
-
27944453927
-
Safety of enfuvirtide in combination with an optimized background of antiretrovirals in treatment-experienced HIV-1-infected adults over 48 weeks
-
Trottier B, Walmsley S, Reynes J, et al. Safety of enfuvirtide in combination with an optimized background of antiretrovirals in treatment-experienced HIV-1-infected adults over 48 weeks. J Acquir Immune Defic Syndr 2005;40(4):413-21
-
(2005)
J Acquir Immune Defic Syndr
, vol.40
, Issue.4
, pp. 413-421
-
-
Trottier, B.1
Walmsley, S.2
Reynes, J.3
-
19
-
-
2942642589
-
Lack of interaction between enfuvirtide and ritonavir or ritonavir-boosted saquinavir in HIV-1-infected patients
-
Ruxrungtham K, Boyd M, Bellibas SE, et al. Lack of interaction between enfuvirtide and ritonavir or ritonavir-boosted saquinavir in HIV-1-infected patients. J Clin Pharmacol 2004;44(7):793-803
-
(2004)
J Clin Pharmacol
, vol.44
, Issue.7
, pp. 793-803
-
-
Ruxrungtham, K.1
Boyd, M.2
Bellibas, S.E.3
-
20
-
-
0242469076
-
Lack of enzyme-inducing effect of rifampicin on the pharmacokinetics of enfuvirtide
-
Boyd MA, Zhang X, Dorr A, et al. Lack of enzyme-inducing effect of rifampicin on the pharmacokinetics of enfuvirtide. J Clin Pharmacol 2003;43(12):1382-91
-
(2003)
J Clin Pharmacol
, vol.43
, Issue.12
, pp. 1382-1391
-
-
Boyd, M.A.1
Zhang, X.2
Dorr, A.3
-
21
-
-
2942594069
-
Assessment of drug-drug interaction potential of enfuvirtide in human immunodeficiency virus type 1-infected patients
-
Zhang X, Lalezari JP, Badley AD, et al. Assessment of drug-drug interaction potential of enfuvirtide in human immunodeficiency virus type 1-infected patients. Clin Pharmacol Ther 2004;75(6):558-68
-
(2004)
Clin Pharmacol Ther
, vol.75
, Issue.6
, pp. 558-568
-
-
Zhang, X.1
Lalezari, J.P.2
Badley, A.D.3
-
22
-
-
33748893949
-
Unexpected drug-drug interaction between tipranavir/ritonavir and enfuvirtide
-
Gonzalez de Requena D, Calcagno A, Bonora S, et al. Unexpected drug-drug interaction between tipranavir/ritonavir and enfuvirtide. AIDS 2006;20(15):1977-9
-
(2006)
AIDS
, vol.20
, Issue.15
, pp. 1977-1979
-
-
Gonzalez de Requena, D.1
Calcagno, A.2
Bonora, S.3
-
23
-
-
34548321373
-
Combined tipranavir and enfuvirtide use associated with higher plasma tipranavir concentrations but not with increased hepatotoxicity: Sub-analysis from RESIST
-
Raffi F, Battegay M, Rusconi S, et al. Combined tipranavir and enfuvirtide use associated with higher plasma tipranavir concentrations but not with increased hepatotoxicity: sub-analysis from RESIST AIDS 2007;21(14):1977-80
-
(2007)
AIDS
, vol.21
, Issue.14
, pp. 1977-1980
-
-
Raffi, F.1
Battegay, M.2
Rusconi, S.3
-
24
-
-
33746783179
-
Pharmacokinetic evaluation of potential interaction between tipranavir and enfuvirtide
-
abstract 53, 20-22 April, Lisbon, Portugal
-
Curran A, Lopez R, Pou L, et al. Pharmacokinetic evaluation of potential interaction between tipranavir and enfuvirtide [abstract 53]. Proceedings of the 7th international workshop on clinical pharmacology of HIV therapy. 20-22 April 2006; Lisbon, Portugal
-
(2006)
Proceedings of the 7th international workshop on clinical pharmacology of HIV therapy
-
-
Curran, A.1
Lopez, R.2
Pou, L.3
-
25
-
-
33746833432
-
Absence of an interaction between the potent HIV protease inhibitor TMC114 and the fusion inhibitor enfuvirtide in the POWER 3 analysis
-
abstract 54, 20-22 April, Lisbon, Portugal
-
Sekar V, De Paepe E, Vangeneugden T, et al. Absence of an interaction between the potent HIV protease inhibitor TMC114 and the fusion inhibitor enfuvirtide in the POWER 3 analysis [abstract 54]. 7th International Workshop on Clinical Pharmacology of HIV Therapy; 20-22 April 2006; Lisbon, Portugal
-
(2006)
7th International Workshop on Clinical Pharmacology of HIV Therapy
-
-
Sekar, V.1
De Paepe, E.2
Vangeneugden, T.3
-
26
-
-
33748115445
-
Rapid emergence of enfuvirtide resistance in HIV-1-infected patients: Results of a clonal analysis
-
Lu J, Deeks SG, Hoh R, et al. Rapid emergence of enfuvirtide resistance in HIV-1-infected patients: results of a clonal analysis. J Acquir Immune Defic Syndr 2006;43(1):60-4
-
(2006)
J Acquir Immune Defic Syndr
, vol.43
, Issue.1
, pp. 60-64
-
-
Lu, J.1
Deeks, S.G.2
Hoh, R.3
-
27
-
-
0036090585
-
Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy
-
Wei X, Decker JM, Liu H, et al. Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy. Antimicrob Agents Chemother 2002;46(6):1896-905
-
(2002)
Antimicrob Agents Chemother
, vol.46
, Issue.6
, pp. 1896-1905
-
-
Wei, X.1
Decker, J.M.2
Liu, H.3
-
28
-
-
52349101378
-
-
Roche Laboratories Inc. and Trimeris, Inc. Fuzeon full prescribing information, Available from:, Last accessed 19 February 2008
-
Roche Laboratories Inc. and Trimeris, Inc. Fuzeon full prescribing information, 2007. Available from: http://www.rocheusa.com/products/ fuzeon/pi.pdf [Last accessed 19 February 2008]
-
(2007)
-
-
-
29
-
-
0037667047
-
Large-scale manufacture of peptide therapeutics by chemical synthesis
-
Bray BL. Large-scale manufacture of peptide therapeutics by chemical synthesis. Nat Rev Drug Discov 2003;2(7):587-93
-
(2003)
Nat Rev Drug Discov
, vol.2
, Issue.7
, pp. 587-593
-
-
Bray, B.L.1
-
30
-
-
18644369147
-
The appealing story of HIV entry inhibitors: From discovery of biological mechanisms to drug development
-
Castagna A, Biswas P, Beretta A, et al. The appealing story of HIV entry inhibitors: from discovery of biological mechanisms to drug development. Drugs 2005;65(7):879-904
-
(2005)
Drugs
, vol.65
, Issue.7
, pp. 879-904
-
-
Castagna, A.1
Biswas, P.2
Beretta, A.3
-
31
-
-
0037799388
-
Fusion inhibition - a major but costly step forward in the treatment of HIV-1
-
Tashima KT, Carpenter CC. Fusion inhibition - a major but costly step forward in the treatment of HIV-1. N Engl J Med 2003;348(22):2249-50
-
(2003)
N Engl J Med
, vol.348
, Issue.22
, pp. 2249-2250
-
-
Tashima, K.T.1
Carpenter, C.C.2
-
32
-
-
34147124231
-
Protein design of a bacterially expressed HIV-1 gp41 fusion inhibitor
-
Deng Y, Zheng Q, Ketas TJ, et al. Protein design of a bacterially expressed HIV-1 gp41 fusion inhibitor. Biochemistry 2007;46(14):4360-9
-
(2007)
Biochemistry
, vol.46
, Issue.14
, pp. 4360-4369
-
-
Deng, Y.1
Zheng, Q.2
Ketas, T.J.3
-
34
-
-
0034924823
-
Mechanisms of viral membrane fusion and its inhibition
-
Eckert DM, Kim PS. Mechanisms of viral membrane fusion and its inhibition. Ann Rev Biochem 2001;70:777-810
-
(2001)
Ann Rev Biochem
, vol.70
, pp. 777-810
-
-
Eckert, D.M.1
Kim, P.S.2
-
35
-
-
0037323819
-
Stopping HIV fusion with enfuvirtide: The first step to extracellular HAART
-
Moyle G. Stopping HIV fusion with enfuvirtide: the first step to extracellular HAART. J Antimicrob Chemother 2003;51(2):213-7
-
(2003)
J Antimicrob Chemother
, vol.51
, Issue.2
, pp. 213-217
-
-
Moyle, G.1
-
37
-
-
0042924181
-
Virus entry as a target for anti-HIV intervention
-
Este JA. Virus entry as a target for anti-HIV intervention. Curr Med Chem 2003;10(17):1617-32
-
(2003)
Curr Med Chem
, vol.10
, Issue.17
, pp. 1617-1632
-
-
Este, J.A.1
-
38
-
-
33645116573
-
HIV entry inhibitors: Mechanisms of action and resistance pathways
-
Briz V, Poveda E, Soriano V. HIV entry inhibitors: mechanisms of action and resistance pathways. J Antimicrob Chemother 2006;57(4):619-27
-
(2006)
J Antimicrob Chemother
, vol.57
, Issue.4
, pp. 619-627
-
-
Briz, V.1
Poveda, E.2
Soriano, V.3
-
39
-
-
34347378496
-
HIV entry inhibitors
-
Este JA, Telenti A. HIV entry inhibitors. Lancet 2007;370(9581):81-8
-
(2007)
Lancet
, vol.370
, Issue.9581
, pp. 81-88
-
-
Este, J.A.1
Telenti, A.2
-
40
-
-
15744393651
-
Different from the HIV fusion inhibitor C34, the anti-HIV drug fuzeon (T-20) inhibits HIV-1 entry by targeting multiple sites in gp41 and gp120
-
Liu S, Lu H, Niu J, et al. Different from the HIV fusion inhibitor C34, the anti-HIV drug fuzeon (T-20) inhibits HIV-1 entry by targeting multiple sites in gp41 and gp120. J Biol Chem 2005;280(12):11259-73
-
(2005)
J Biol Chem
, vol.280
, Issue.12
, pp. 11259-11273
-
-
Liu, S.1
Lu, H.2
Niu, J.3
-
41
-
-
33846081762
-
Susceptibility of HIV-1 non-B subtypes and recombinant variants to enfuvirtide
-
Holguin A, Faudon JL, Labernardiere JL, et al. Susceptibility of HIV-1 non-B subtypes and recombinant variants to enfuvirtide. J Clin Virol 2007;38(2):176-80
-
(2007)
J Clin Virol
, vol.38
, Issue.2
, pp. 176-180
-
-
Holguin, A.1
Faudon, J.L.2
Labernardiere, J.L.3
-
42
-
-
33646146697
-
Susceptibility to antiretroviral drugs of CRF01Æ, CRF02_AG, and subtype C viruses from untreated patients of Africa and Asia: Comparative genotypic and phenotypic data
-
Fleury HJ, Toni T, Lan NT, et al. Susceptibility to antiretroviral drugs of CRF01Æ, CRF02_AG, and subtype C viruses from untreated patients of Africa and Asia: comparative genotypic and phenotypic data. AIDS Res Hum Retroviruses 2006;22(4):357-66
-
(2006)
AIDS Res Hum Retroviruses
, vol.22
, Issue.4
, pp. 357-366
-
-
Fleury, H.J.1
Toni, T.2
Lan, N.T.3
-
43
-
-
2642547308
-
Sensitivity of HIV type 1 subtype C isolates to the entry inhibitor T-20
-
Cilliers T, Patience T, Pillay C, et al. Sensitivity of HIV type 1 subtype C isolates to the entry inhibitor T-20. AIDS Res Hum Retroviruses 2004;20(5):477-82
-
(2004)
AIDS Res Hum Retroviruses
, vol.20
, Issue.5
, pp. 477-482
-
-
Cilliers, T.1
Patience, T.2
Pillay, C.3
-
44
-
-
27544447546
-
Inhibition of HIV-1 group M and O isolates by fusion inhibitors
-
Chinnadurai R, Munch J, Dittmar MT, et al. Inhibition of HIV-1 group M and O isolates by fusion inhibitors. AIDS 2005;19(16):1919-22
-
(2005)
AIDS
, vol.19
, Issue.16
, pp. 1919-1922
-
-
Chinnadurai, R.1
Munch, J.2
Dittmar, M.T.3
-
46
-
-
33646868062
-
Characterization of envelope glycoprotein gp41 genotype and phenotypic susceptibility to enfuvirtide at baseline and on treatment in the phase III clinical trials TORO-1 and TORO-2
-
Melby T, Sista P, DeMasi R, et al. Characterization of envelope glycoprotein gp41 genotype and phenotypic susceptibility to enfuvirtide at baseline and on treatment in the phase III clinical trials TORO-1 and TORO-2. AIDS Res Hum Retroviruses 2006;22(5):375-85
-
(2006)
AIDS Res Hum Retroviruses
, vol.22
, Issue.5
, pp. 375-385
-
-
Melby, T.1
Sista, P.2
DeMasi, R.3
-
47
-
-
1842502574
-
Are fusion inhibitors active against all HIV variants?
-
Poveda E, Rodes B, Toro C, et al. Are fusion inhibitors active against all HIV variants? AIDS Res Hum Retroviruses 2004;20(3):347-8
-
(2004)
AIDS Res Hum Retroviruses
, vol.20
, Issue.3
, pp. 347-348
-
-
Poveda, E.1
Rodes, B.2
Toro, C.3
-
48
-
-
1542319002
-
Susceptibility of HIV-2, SIV and SHIV to various anti-HIV-1 compounds: Implications for treatment and postexposure prophylaxis
-
Witvrouw M, Pannecouque C, Switzer WM, et al. Susceptibility of HIV-2, SIV and SHIV to various anti-HIV-1 compounds: implications for treatment and postexposure prophylaxis. Antivir Ther 2004;9(1)57-65
-
(2004)
Antivir Ther
, vol.9
, Issue.1
, pp. 57-65
-
-
Witvrouw, M.1
Pannecouque, C.2
Switzer, W.M.3
-
49
-
-
0036335809
-
Pharmacokinetics of plasma enfuvirtide after subcutaneous administration to patients with human immunodeficiency virus: Inverse Gaussian density absorption and 2-compartment disposition
-
Zhang X, Nieforth K, Lang JM, et al. Pharmacokinetics of plasma enfuvirtide after subcutaneous administration to patients with human immunodeficiency virus: inverse Gaussian density absorption and 2-compartment disposition. Clin Pharmacol Ther 2002;72(1):10-9
-
(2002)
Clin Pharmacol Ther
, vol.72
, Issue.1
, pp. 10-19
-
-
Zhang, X.1
Nieforth, K.2
Lang, J.M.3
-
50
-
-
0042885473
-
Influence of subcutaneous injection site on the steady-state pharmacokinetics of enfuvirtide (T-20) in HIV-1-infected patients
-
Lalezari JP, Patel IH, Zhang X, et al. Influence of subcutaneous injection site on the steady-state pharmacokinetics of enfuvirtide (T-20) in HIV-1-infected patients. J Clin Virol 2003;28(2):217-22
-
(2003)
J Clin Virol
, vol.28
, Issue.2
, pp. 217-222
-
-
Lalezari, J.P.1
Patel, I.H.2
Zhang, X.3
-
51
-
-
33745095614
-
Enfuvirtide plasma levels and injection site reactions using a needle-free gas-powered injection system (Biojector)
-
Harris M, Joy R, Larsen G, et al. Enfuvirtide plasma levels and injection site reactions using a needle-free gas-powered injection system (Biojector). AIDS 2006;20(5):719-23
-
(2006)
AIDS
, vol.20
, Issue.5
, pp. 719-723
-
-
Harris, M.1
Joy, R.2
Larsen, G.3
-
52
-
-
33845351001
-
Pharmacokinetic bioequivalence of enfuvirtide using a needle-free device versus standard needle administration
-
True AL, Chiu YY, Demasi RA, et al. Pharmacokinetic bioequivalence of enfuvirtide using a needle-free device versus standard needle administration. Pharmacotherapy 2006;26(12):1679-86
-
(2006)
Pharmacotherapy
, vol.26
, Issue.12
, pp. 1679-1686
-
-
True, A.L.1
Chiu, Y.Y.2
Demasi, R.A.3
-
53
-
-
4744357409
-
-
Ghosn J, Chaix ML, Peytavin G, et al. Penetration of enfuvirtide, tenofovir, efavirenz, and protease inhibitors in the genital tract of HIV-1-infected men. AIDS 2004;18(14):1958-61
-
Ghosn J, Chaix ML, Peytavin G, et al. Penetration of enfuvirtide, tenofovir, efavirenz, and protease inhibitors in the genital tract of HIV-1-infected men. AIDS 2004;18(14):1958-61
-
-
-
-
54
-
-
38349068747
-
Validation of the CNS penetration-effectiveness rank for quantifying antiretroviral penetration into the central nervous system
-
Letendre S, Marquie-Beck J, Capparelli E, et al. Validation of the CNS penetration-effectiveness rank for quantifying antiretroviral penetration into the central nervous system. Arch Neurol 2008;65(1):65-70
-
(2008)
Arch Neurol
, vol.65
, Issue.1
, pp. 65-70
-
-
Letendre, S.1
Marquie-Beck, J.2
Capparelli, E.3
-
56
-
-
31944450675
-
Pharmacokinetics of enfuvirtide in patients treated in typical routine clinical settings
-
Stocker H, Kloft C, Plock N, et al. Pharmacokinetics of enfuvirtide in patients treated in typical routine clinical settings. Antimicrob Agents Chemother 2006;50(2):667-73
-
(2006)
Antimicrob Agents Chemother
, vol.50
, Issue.2
, pp. 667-673
-
-
Stocker, H.1
Kloft, C.2
Plock, N.3
-
57
-
-
20444470810
-
Population pharmacokinetics and exposure response relationship of enfuvirtide in treatment experienced human immunodeficiency virus type 1 infected patients
-
Mould DR, Zhang X, Nieforth K, et al. Population pharmacokinetics and exposure response relationship of enfuvirtide in treatment experienced human immunodeficiency virus type 1 infected patients. Clin Pharmacol Ther 2005;77:515-28
-
(2005)
Clin Pharmacol Ther
, vol.77
, pp. 515-528
-
-
Mould, D.R.1
Zhang, X.2
Nieforth, K.3
-
58
-
-
47249085264
-
Pharmacokinetic and pharmacodynamic determinants of early virological response to enfuvirtide-based regimens in HIV-positive patients
-
Gonzalez de Requena D, Bonora S, Castagna A, et al. Pharmacokinetic and pharmacodynamic determinants of early virological response to enfuvirtide-based regimens in HIV-positive patients. Journal of Antimicrobial Chemotherapy 2008;62(2):384-387
-
(2008)
Journal of Antimicrobial Chemotherapy
, vol.62
, Issue.2
, pp. 384-387
-
-
Gonzalez de Requena, D.1
Bonora, S.2
Castagna, A.3
-
59
-
-
42449124874
-
Enfuvirtide does not require dose adjustment in patients with chronic kidney failure: Results of a pharmacokinetic study of enfuvirtide in HIV-1-infected patients with impaired kidney function
-
Tebas P, Bellos N, Lucasti C, et al. Enfuvirtide does not require dose adjustment in patients with chronic kidney failure: results of a pharmacokinetic study of enfuvirtide in HIV-1-infected patients with impaired kidney function. J Acquir Immune Defic Syndr 2008;47(3):342-5
-
(2008)
J Acquir Immune Defic Syndr
, vol.47
, Issue.3
, pp. 342-345
-
-
Tebas, P.1
Bellos, N.2
Lucasti, C.3
-
60
-
-
13244286223
-
T20-310/NV16056 Study Group. Pharmacokinetics of enfuvirtide in pediatric human immunodeficiency virus 1-infected patients receiving combination therapy
-
Bellibas SE, Siddique Z, Derr A, et al.; T20-310/NV16056 Study Group. Pharmacokinetics of enfuvirtide in pediatric human immunodeficiency virus 1-infected patients receiving combination therapy. Pediatr Infect Dis J 2004;23(12):1137-41
-
(2004)
Pediatr Infect Dis J
, vol.23
, Issue.12
, pp. 1137-1141
-
-
Bellibas, S.E.1
Siddique, Z.2
Derr, A.3
-
61
-
-
33947491458
-
T20-310/NV16056 Study Group. Population pharmacokinetics of enfuvirtide in HIV-1-infected pediatric patients over 48 weeks of treatment
-
Zhang X, Lin T, Bertasso A, et al.; T20-310/NV16056 Study Group. Population pharmacokinetics of enfuvirtide in HIV-1-infected pediatric patients over 48 weeks of treatment. J Clin Pharmacol 2007;47(4):510-7
-
(2007)
J Clin Pharmacol
, vol.47
, Issue.4
, pp. 510-517
-
-
Zhang, X.1
Lin, T.2
Bertasso, A.3
-
62
-
-
4744362280
-
Enfuvirtide prescription at the end of pregnancy to a multi-treated HIV-infected woman with virological breakthrough
-
Meyohas MC, Lacombe K, Carbonne B, et al. Enfuvirtide prescription at the end of pregnancy to a multi-treated HIV-infected woman with virological breakthrough. AIDS 2004;18(14):1966-8
-
(2004)
AIDS
, vol.18
, Issue.14
, pp. 1966-1968
-
-
Meyohas, M.C.1
Lacombe, K.2
Carbonne, B.3
-
63
-
-
20644448396
-
Perinatal transmission of multidrug-resistant HIV-1 despite viral suppression on an enfuvirtide-based treatment regimen
-
Cohan D, Feakins C, Wara D, et al. Perinatal transmission of multidrug-resistant HIV-1 despite viral suppression on an enfuvirtide-based treatment regimen. AIDS 2005;19(9):989-90
-
(2005)
AIDS
, vol.19
, Issue.9
, pp. 989-990
-
-
Cohan, D.1
Feakins, C.2
Wara, D.3
-
64
-
-
33646065346
-
Enfurvitide prevents vertical transmission of multidrug-resistant HIV-1 in pregnancy but does not cross the placenta
-
Brennan-Benson P, Pakianathan M, Rice P, et al. Enfurvitide prevents vertical transmission of multidrug-resistant HIV-1 in pregnancy but does not cross the placenta. AIDS 2006;20(2):297-9
-
(2006)
AIDS
, vol.20
, Issue.2
, pp. 297-299
-
-
Brennan-Benson, P.1
Pakianathan, M.2
Rice, P.3
-
65
-
-
33645018470
-
Pharmacokinetics, pharmacodynamics and safety of once-daily versus twice-daily dosing with enfuvirtide in HIV-infected subjects
-
Thompson M, DeJesus E, Richmond G, et al. Pharmacokinetics, pharmacodynamics and safety of once-daily versus twice-daily dosing with enfuvirtide in HIV-infected subjects. AIDS 2006;20(3):397-404
-
(2006)
AIDS
, vol.20
, Issue.3
, pp. 397-404
-
-
Thompson, M.1
DeJesus, E.2
Richmond, G.3
-
66
-
-
13244288179
-
Pharmacokinetics, pharmacodynamics and drug interaction potential of enfuvirtide
-
Patel IH, Zhang X, Nieforth K, et al. Pharmacokinetics, pharmacodynamics and drug interaction potential of enfuvirtide. Clin Pharmacokinet 2005;44(2):175-86
-
(2005)
Clin Pharmacokinet
, vol.44
, Issue.2
, pp. 175-186
-
-
Patel, I.H.1
Zhang, X.2
Nieforth, K.3
-
67
-
-
52349083924
-
Genotypic relationships between tipranavir and darunavir resistance in protease inhibitor experienced patients
-
abstract 79, 12-16 June, Barbados, West Indies
-
Hall D, Scherer J, Schapiro J, et al. Genotypic relationships between tipranavir and darunavir resistance in protease inhibitor experienced patients [abstract 79]. Proceedings of the 16th international HIV drug resistance workshop; 12-16 June 2007; Barbados, West Indies
-
(2007)
Proceedings of the 16th international HIV drug resistance workshop
-
-
Hall, D.1
Scherer, J.2
Schapiro, J.3
-
68
-
-
33646868062
-
Characterization of envelope glycoprotein gp41 genotype and phenotypic susceptibility to enfuvirtide at baseline and on treatment in the phase III clinical trials TORO-1 and TORO-2
-
Melby T, Sista P, DeMasi R, et al. Characterization of envelope glycoprotein gp41 genotype and phenotypic susceptibility to enfuvirtide at baseline and on treatment in the phase III clinical trials TORO-1 and TORO-2. AIDS Res Hum Retroviruses 2006;22(5):375-85
-
(2006)
AIDS Res Hum Retroviruses
, vol.22
, Issue.5
, pp. 375-385
-
-
Melby, T.1
Sista, P.2
DeMasi, R.3
-
69
-
-
4444310448
-
Characterization of determinants of genotypic and phenotypic resistance to enfuvirtide in baseline and on-treatment HIV-1 isolates
-
Sista PR, Melby T, Davison D, et al. Characterization of determinants of genotypic and phenotypic resistance to enfuvirtide in baseline and on-treatment HIV-1 isolates. AIDS 2004;18(13):1787-94
-
(2004)
AIDS
, vol.18
, Issue.13
, pp. 1787-1794
-
-
Sista, P.R.1
Melby, T.2
Davison, D.3
-
70
-
-
27744464493
-
Dynamics of enfuvirtide resistance in HIV-infected patients during and after long-term enfuvirtide salvage therapy
-
Poveda E, Rodes B, Lebel-Binay S, et al. Dynamics of enfuvirtide resistance in HIV-infected patients during and after long-term enfuvirtide salvage therapy. J Clin Virol 2005;34(4):295-301
-
(2005)
J Clin Virol
, vol.34
, Issue.4
, pp. 295-301
-
-
Poveda, E.1
Rodes, B.2
Lebel-Binay, S.3
-
71
-
-
20044371998
-
Emergence and evolution of enfuvirtide resistance following long-term therapy involves heptad repeat 2 mutations within gp41
-
Xu L, Pozniak A, Wildfire A, et al. Emergence and evolution of enfuvirtide resistance following long-term therapy involves heptad repeat 2 mutations within gp41. Antimicrob Agents Chemother 2005;49(3):1113-9
-
(2005)
Antimicrob Agents Chemother
, vol.49
, Issue.3
, pp. 1113-1119
-
-
Xu, L.1
Pozniak, A.2
Wildfire, A.3
-
72
-
-
31144436790
-
Long-term monitoring of genotypic and phenotypic resistance to T20 in treated patients infected with HIV-1
-
Perez-Alvarez L, Carmona R, Ocampo A, et al. Long-term monitoring of genotypic and phenotypic resistance to T20 in treated patients infected with HIV-1. J Med Virol 2006;78(2):141-7
-
(2006)
J Med Virol
, vol.78
, Issue.2
, pp. 141-147
-
-
Perez-Alvarez, L.1
Carmona, R.2
Ocampo, A.3
-
73
-
-
33745993903
-
Genotypic changes in human immunodeficiency virus type 1 envelope glycoproteins on treatment with the fusion inhibitor enfuvirtide and their influence on changes in drug susceptibility in vitro
-
Su C, Melby T, DeMasi R, et al. Genotypic changes in human immunodeficiency virus type 1 envelope glycoproteins on treatment with the fusion inhibitor enfuvirtide and their influence on changes in drug susceptibility in vitro. J Clin Virol 2006;36(4):249-57
-
(2006)
J Clin Virol
, vol.36
, Issue.4
, pp. 249-257
-
-
Su, C.1
Melby, T.2
DeMasi, R.3
-
74
-
-
33748684791
-
Specific mutations in HIV-1 gp41 are associated with immunological success in HIV-1-infected patients receiving enfuvirtide treatment
-
Aquaro S, D'Arrigo R, Svicher V, et al. Specific mutations in HIV-1 gp41 are associated with immunological success in HIV-1-infected patients receiving enfuvirtide treatment. J Antimicrob Chemother 2006;58(4):714-22
-
(2006)
J Antimicrob Chemother
, vol.58
, Issue.4
, pp. 714-722
-
-
Aquaro, S.1
D'Arrigo, R.2
Svicher, V.3
-
75
-
-
34748887166
-
Variants with different mutation patterns persist in the quasispecies of enfuvirtide-resistant HIV-1 population during and after treatment in vivo
-
Trabaud MA, Cotte L, Labernardiere JL, et al. Variants with different mutation patterns persist in the quasispecies of enfuvirtide-resistant HIV-1 population during and after treatment in vivo. J Acquir Immune Defic Syndr 2007;46(2):134-144
-
(2007)
J Acquir Immune Defic Syndr
, vol.46
, Issue.2
, pp. 134-144
-
-
Trabaud, M.A.1
Cotte, L.2
Labernardiere, J.L.3
-
76
-
-
0037059049
-
Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics
-
Reeves JD, Gallo SA, Ahmad N, et al. Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics. Proc Natl Acad Sci USA 2002;99(25):16249-54
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.25
, pp. 16249-16254
-
-
Reeves, J.D.1
Gallo, S.A.2
Ahmad, N.3
-
77
-
-
0034890660
-
Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor
-
Derdeyn CA, Decker JM, Sfakianos JN, et al. Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor. J Virol 2001;75(18):8605-14
-
(2001)
J Virol
, vol.75
, Issue.18
, pp. 8605-8614
-
-
Derdeyn, C.A.1
Decker, J.M.2
Sfakianos, J.N.3
-
78
-
-
0042895999
-
Analysis of baseline enfuvirtide (T-20) susceptibility and co-receptor tropism in two phase III study populations
-
abstract 557, 10-14 February, Boston, Massachusetts, USA
-
Whitcomb J, Huang W, Fransen S, et al. Analysis of baseline enfuvirtide (T-20) susceptibility and co-receptor tropism in two phase III study populations [abstract 557]. Proceedings of the 10th Conference on Retroviruses and Opportunistic Infections (CROI); 10-14 February 2003; Boston, Massachusetts, USA
-
(2003)
Proceedings of the 10th Conference on Retroviruses and Opportunistic Infections (CROI)
-
-
Whitcomb, J.1
Huang, W.2
Fransen, S.3
-
79
-
-
16244380203
-
Enfuvirtide resistance mutations: Impact on human immunodeficiency virus envelope function, entry inhibitor sensitivity, and virus neutralization
-
Reeves JD, Lee FH, Miamidian JL, et al. Enfuvirtide resistance mutations: impact on human immunodeficiency virus envelope function, entry inhibitor sensitivity, and virus neutralization. J Virol 2005;79(8):4991-9
-
(2005)
J Virol
, vol.79
, Issue.8
, pp. 4991-4999
-
-
Reeves, J.D.1
Lee, F.H.2
Miamidian, J.L.3
-
80
-
-
33846456210
-
Interruption of enfuvirtide in HIV-1 infected adults with incomplete viral suppression on an enfuvirtide-based regimen
-
Deeks SG, Lu J, Hoh R, et al. Interruption of enfuvirtide in HIV-1 infected adults with incomplete viral suppression on an enfuvirtide-based regimen. J Infect Dis 2007;195(3):387-91
-
(2007)
J Infect Dis
, vol.195
, Issue.3
, pp. 387-391
-
-
Deeks, S.G.1
Lu, J.2
Hoh, R.3
-
81
-
-
34548222239
-
Virological fitness of HIV in patients with resistance to enfuvirtide
-
Chibo D, Roth N, Roulet V, et al. Virological fitness of HIV in patients with resistance to enfuvirtide. AIDS 2007;21(14):1974-7
-
(2007)
AIDS
, vol.21
, Issue.14
, pp. 1974-1977
-
-
Chibo, D.1
Roth, N.2
Roulet, V.3
-
82
-
-
33748669404
-
Role of the envelope genetic context in the development of enfuvirtide resistance in human immunodeficiency virus type 1-infected patients
-
Labrosse B, Morand-Joubert L, Goubard A, et al. Role of the envelope genetic context in the development of enfuvirtide resistance in human immunodeficiency virus type 1-infected patients. J Virol 2006;80(17):8807-19
-
(2006)
J Virol
, vol.80
, Issue.17
, pp. 8807-8819
-
-
Labrosse, B.1
Morand-Joubert, L.2
Goubard, A.3
-
83
-
-
43949084344
-
Specific enfuvirtide-associated mutational pathways in HIV-1 Gp41 are significantly correlated with an increase in CD4(+) cell count, despite virological failure
-
Vicher V, Aquaro S, D'Arrigo R, et al. Specific enfuvirtide-associated mutational pathways in HIV-1 Gp41 are significantly correlated with an increase in CD4(+) cell count, despite virological failure. J Infect Dis 2008;197(10):1408-18
-
(2008)
J Infect Dis
, vol.197
, Issue.10
, pp. 1408-1418
-
-
Vicher, V.1
Aquaro, S.2
D'Arrigo, R.3
-
84
-
-
36348936125
-
Association between specific enfuvirtide resistance mutations and CD4 cell response during enfuvirtide-based therapy
-
Melby TE, Despirito M, Demasi RA, et al. Association between specific enfuvirtide resistance mutations and CD4 cell response during enfuvirtide-based therapy. AIDS 2007;21(18):2537-9
-
(2007)
AIDS
, vol.21
, Issue.18
, pp. 2537-2539
-
-
Melby, T.E.1
Despirito, M.2
Demasi, R.A.3
-
85
-
-
33748784375
-
Performance of human immunodeficiency virus type 1 gp41 assays for detecting enfuvirtide (T-20) resistance mutations
-
Marcial M, Lu J, Deeks SG, et al. Performance of human immunodeficiency virus type 1 gp41 assays for detecting enfuvirtide (T-20) resistance mutations. J Clin Microbiol 2006;44(9):3384-7
-
(2006)
J Clin Microbiol
, vol.44
, Issue.9
, pp. 3384-3387
-
-
Marcial, M.1
Lu, J.2
Deeks, S.G.3
-
86
-
-
9944239729
-
A genotypic resistance assay for the detection of drug resistance in the human immunodeficiency virus type 1 envelope gene
-
Van Laethem K, Schrooten Y, Lemey P, et al. A genotypic resistance assay for the detection of drug resistance in the human immunodeficiency virus type 1 envelope gene. J Virol Methods 2005;123(1):25-34
-
(2005)
J Virol Methods
, vol.123
, Issue.1
, pp. 25-34
-
-
Van Laethem, K.1
Schrooten, Y.2
Lemey, P.3
-
87
-
-
1842502994
-
Enfuvirtide: A fusion inhibitor for the treatment of HIV infection
-
Fung HB, Guo Y. Enfuvirtide: a fusion inhibitor for the treatment of HIV infection. Clin Ther 2004;26(3):352-78
-
(2004)
Clin Ther
, vol.26
, Issue.3
, pp. 352-378
-
-
Fung, H.B.1
Guo, Y.2
-
88
-
-
17144420144
-
Enfuvirtide: The first HIV fusion inhibitor
-
Lazzarin A. Enfuvirtide: the first HIV fusion inhibitor. Expert Opin Pharmacother 2005;6(3):453-64
-
(2005)
Expert Opin Pharmacother
, vol.6
, Issue.3
, pp. 453-464
-
-
Lazzarin, A.1
-
89
-
-
20544456150
-
-
Oldfield V, Keating GM, Plosker G. Enfuvirtide: a review of its use in the management of HIV infection. Drugs 2005;65(8):1139-60. Erratum appears in: Drugs 2005;6512:1667
-
Oldfield V, Keating GM, Plosker G. Enfuvirtide: a review of its use in the management of HIV infection. Drugs 2005;65(8):1139-60. Erratum appears in: Drugs 2005;6512:1667
-
-
-
-
90
-
-
8344271311
-
Enfuvirtide: First fusion inhibitor for treatment of HIV infection
-
Jamjian MC, McNicholl IR. Enfuvirtide: first fusion inhibitor for treatment of HIV infection. Am J Health-System Pharm 2004;61(12):1242-7
-
(2004)
Am J Health-System Pharm
, vol.61
, Issue.12
, pp. 1242-1247
-
-
Jamjian, M.C.1
McNicholl, I.R.2
-
91
-
-
27944473910
-
Durable efficacy of enfuvirtide over 48 weeks in heavily treatment-experienced HIV-1-infected patients in the T-20 versus optimized background regimen only 1 and 2 clinical trials
-
Nelson M, Arasteh K, Clotet B, et al. Durable efficacy of enfuvirtide over 48 weeks in heavily treatment-experienced HIV-1-infected patients in the T-20 versus optimized background regimen only 1 and 2 clinical trials. J Acquir Immune Defic Syndr 2005;40(4):404-12
-
(2005)
J Acquir Immune Defic Syndr
, vol.40
, Issue.4
, pp. 404-412
-
-
Nelson, M.1
Arasteh, K.2
Clotet, B.3
-
92
-
-
35448948367
-
TORO: Ninety-six-week virologic and immunologic response and safety evaluation of enfuvirtide with an optimized background of antiretrovirals
-
Reynes J, Arasteh K, Clotet B, et al. TORO: ninety-six-week virologic and immunologic response and safety evaluation of enfuvirtide with an optimized background of antiretrovirals. AIDS Patient Care STDS 2007;21(8):533-43
-
(2007)
AIDS Patient Care STDS
, vol.21
, Issue.8
, pp. 533-543
-
-
Reynes, J.1
Arasteh, K.2
Clotet, B.3
-
93
-
-
1642314025
-
Efficacy of enfuvirtide in subgroups of patients through 48 weeks of therapy in the TORO trials
-
abstract no, October, Warsaw, Poland
-
Walmsley S, Clotet B, Cooper D, et al. Efficacy of enfuvirtide in subgroups of patients through 48 weeks of therapy in the TORO trials [abstract no. 7.3/15 plus poster]. Proceedings of the 9th European AIDS Conference and 1st EACS resistance and pharmacology workshop; 25-29 October 2003; Warsaw, Poland
-
(2003)
7.3/15 plus poster]. Proceedings of the 9th European AIDS Conference and 1st EACS resistance and pharmacology workshop; 25-29
-
-
Walmsley, S.1
Clotet, B.2
Cooper, D.3
-
95
-
-
17144407126
-
Early viral load responses on enfuvirtide in heavily treatment-experienced patients
-
abstract TuPeB4484, 11-16 July, Bangkok, Thailand
-
Bartlett J, Salgo M, DeMasi R. Early viral load responses on enfuvirtide in heavily treatment-experienced patients [abstract TuPeB4484]. Proceedings of the 15th International AIDS Conference. 11-16 July 2004; Bangkok, Thailand
-
(2004)
Proceedings of the 15th International AIDS Conference
-
-
Bartlett, J.1
Salgo, M.2
DeMasi, R.3
-
96
-
-
20544475848
-
Adherence to enfuvirtide and to background antiretroviral therapy over 48 weeks and its impact on treatment efficacy
-
abstract WePeB5822, 11-16 July, Bangkok, Thailand
-
Witek J, Rockstroh J, Donatacci L, et al. Adherence to enfuvirtide and to background antiretroviral therapy over 48 weeks and its impact on treatment efficacy [abstract WePeB5822]. Proceedings of the 15th International AIDS Conference; 11-16 July 2004; Bangkok, Thailand
-
(2004)
Proceedings of the 15th International AIDS Conference
-
-
Witek, J.1
Rockstroh, J.2
Donatacci, L.3
-
97
-
-
52349100138
-
An intensification treatment strategy of adding enfuvirtide to an oral HAART regimen: The INTENSE study 24 week induction phase analysis [poster P4.3/73]
-
24-27 October, Madrid, Spain
-
Clotet B, Capetti A, Soto-Ramirez L, et al. An intensification treatment strategy of adding enfuvirtide to an oral HAART regimen: the INTENSE study 24 week induction phase analysis [poster P4.3/73]. 11th European Aids Conference (EACS); 24-27 October 2007; Madrid, Spain.
-
(2007)
11th European Aids Conference (EACS)
-
-
Clotet, B.1
Capetti, A.2
Soto-Ramirez, L.3
-
98
-
-
44949158720
-
Efficacy and safety of 48 weeks of enfuvirtide 180 mg once-daily dosing versus 90 mg twice-daily dosing in HIV-infected patients
-
Wright D, Rodriguez A, Godofsky E, et al. Efficacy and safety of 48 weeks of enfuvirtide 180 mg once-daily dosing versus 90 mg twice-daily dosing in HIV-infected patients. HIV Clin Trials 2008;9(2):73-82
-
(2008)
HIV Clin Trials
, vol.9
, Issue.2
, pp. 73-82
-
-
Wright, D.1
Rodriguez, A.2
Godofsky, E.3
-
100
-
-
34548203506
-
Safety and efficacy of enfuvirtide for 48 weeks as part of an optimized antiretroviral regimen in pediatric human immunodeficiency virus 1-infected patients
-
Wiznia A, Church J, Emmanuel P, et al. Safety and efficacy of enfuvirtide for 48 weeks as part of an optimized antiretroviral regimen in pediatric human immunodeficiency virus 1-infected patients. Pediatr Infect Dis J 2007;26(9):799-805
-
(2007)
Pediatr Infect Dis J
, vol.26
, Issue.9
, pp. 799-805
-
-
Wiznia, A.1
Church, J.2
Emmanuel, P.3
-
101
-
-
52349106162
-
On behalf of the Alliance Investigator Group. An analysis of the correlation between the severity of injection site reactions and the amount of subcutaneous fat in the alliance cohort
-
abstract 838, 22-25 February, Boston, Massachusetts, USA
-
Cooper D; On behalf of the Alliance Investigator Group. An analysis of the correlation between the severity of injection site reactions and the amount of subcutaneous fat in the alliance cohort [abstract 838]. Proceedings of the 12th Conference on Retroviruses and Opportunistic Infections (CROI); 22-25 February 2005; Boston, Massachusetts, USA
-
(2005)
Proceedings of the 12th Conference on Retroviruses and Opportunistic Infections (CROI)
-
-
Cooper, D.1
-
102
-
-
34047268161
-
Quality of life and tolerability after administration of enfuvirtide with a thin-walled needle: QUALITE study
-
Shalit P, True A, Thommes JA, et al. Quality of life and tolerability after administration of enfuvirtide with a thin-walled needle: QUALITE study. HIV Clin Trials 2007;8(1):24-35
-
(2007)
HIV Clin Trials
, vol.8
, Issue.1
, pp. 24-35
-
-
Shalit, P.1
True, A.2
Thommes, J.A.3
-
103
-
-
34548319986
-
Needle-free administration (biojector) or enfuvirtide significantly reduces incidence of painful injection site reactions: Results from a single blind, randomized, controlled study
-
abstract H-1905b, 27-30 September, San Francisco, California, USA
-
Gottlieb M, True A, Evans R, et al. Needle-free administration (biojector) or enfuvirtide significantly reduces incidence of painful injection site reactions: results from a single blind, randomized, controlled study [abstract H-1905b]. 46th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; 27-30 September 2006; San Francisco, California, USA
-
(2006)
46th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Gottlieb, M.1
True, A.2
Evans, R.3
-
104
-
-
34249997233
-
Successful long-course after failure of short-course desensitization in a patient with severe hypersensitivity reaction to enfuvirtide
-
Quiros-Roldan E, Tirelli V, Torti C, et al. Successful long-course after failure of short-course desensitization in a patient with severe hypersensitivity reaction to enfuvirtide. AIDS 2007;21(10):1388-9
-
(2007)
AIDS
, vol.21
, Issue.10
, pp. 1388-1389
-
-
Quiros-Roldan, E.1
Tirelli, V.2
Torti, C.3
-
105
-
-
15944421769
-
Successful desensitization of enfuvirtide-induced skin hypersensitivity reaction
-
Shahar E, Moar C, Pollack S. Successful desensitization of enfuvirtide-induced skin hypersensitivity reaction. AIDS 2005;19(4):451-2
-
(2005)
AIDS
, vol.19
, Issue.4
, pp. 451-452
-
-
Shahar, E.1
Moar, C.2
Pollack, S.3
-
106
-
-
28744442218
-
Successful desensitization to enfuvirtide after a hypersensitivity reaction in an HIV-1-infected man
-
DeSimone JA, Ojha A, Pathak R, et al. Successful desensitization to enfuvirtide after a hypersensitivity reaction in an HIV-1-infected man. Clin Infect Dis 2004;39(10):e110-2
-
(2004)
Clin Infect Dis
, vol.39
, Issue.10
-
-
DeSimone, J.A.1
Ojha, A.2
Pathak, R.3
-
107
-
-
33750236368
-
Successful desensitization of enfuvirtide after a first attempt failure
-
Machado ES, Passoni LF, Sidi LC, et al. Successful desensitization of enfuvirtide after a first attempt failure. AIDS 2006;20(16):2130-1
-
(2006)
AIDS
, vol.20
, Issue.16
, pp. 2130-2131
-
-
Machado, E.S.1
Passoni, L.F.2
Sidi, L.C.3
-
108
-
-
34548398987
-
The safety and efficacy of enfuvirtide therapy for HIV infection in patients with hemophilia: A case series
-
Polizzotto MN, Street AM, Wright E. The safety and efficacy of enfuvirtide therapy for HIV infection in patients with hemophilia: a case series. Clin Infect Dis 2007;45(4):e39-41
-
(2007)
Clin Infect Dis
, vol.45
, Issue.4
-
-
Polizzotto, M.N.1
Street, A.M.2
Wright, E.3
-
109
-
-
9144264190
-
Enfuvirtide (T-20) cross-reactive glycoprotein 41 antibody does not impair the efficacy or safety of enfuvirtide
-
Walmsley S, Henry K, Katlama C, et al. Enfuvirtide (T-20) cross-reactive glycoprotein 41 antibody does not impair the efficacy or safety of enfuvirtide. J Infect Dis 2003;188(12):1827-33
-
(2003)
J Infect Dis
, vol.188
, Issue.12
, pp. 1827-1833
-
-
Walmsley, S.1
Henry, K.2
Katlama, C.3
-
110
-
-
3042663633
-
Patient acceptance of self-injected enfuvirtide for HIV over 48 weeks of treatment
-
abstract 7, October, Warsaw, Poland
-
Cohen C, Green J, Wintfeld N, et al. Patient acceptance of self-injected enfuvirtide for HIV over 48 weeks of treatment [abstract 7. 1/1 plus poster]. 9th European Aids Conference (EACS); 25-29 October 2003; Warsaw, Poland
-
(2003)
1/1 plus poster]. 9th European Aids Conference (EACS); 25-29
-
-
Cohen, C.1
Green, J.2
Wintfeld, N.3
-
112
-
-
4444234979
-
Health-related quality of life with enfuvirtide (ENF; T-20) in combination with an optimized background regimen
-
Cohen CJ, Clumeck N, Molina JM, et al. Health-related quality of life with enfuvirtide (ENF; T-20) in combination with an optimized background regimen. J Acquit Immune Defic Syndr 2004;37(1):1140-6
-
(2004)
J Acquit Immune Defic Syndr
, vol.37
, Issue.1
, pp. 1140-1146
-
-
Cohen, C.J.1
Clumeck, N.2
Molina, J.M.3
-
113
-
-
34548313730
-
A large prospective study assessing injection site reactions, quality of life and preference in patients using the biojector vs. standard needles for enfuvirtide administration
-
Loutfy MR, Harris M, Raboud JM, et al. A large prospective study assessing injection site reactions, quality of life and preference in patients using the biojector vs. standard needles for enfuvirtide administration. HIV Med 2007;8(7):427-32
-
(2007)
HIV Med
, vol.8
, Issue.7
, pp. 427-432
-
-
Loutfy, M.R.1
Harris, M.2
Raboud, J.M.3
-
114
-
-
17144429269
-
Enfurvirtide safety in human immunodeficiency virus-infected children
-
Baylor MS, Johann-Liang R. Enfurvirtide safety in human immunodeficiency virus-infected children. Pediatr Infect Dis J 2005;24(4):389-90
-
(2005)
Pediatr Infect Dis J
, vol.24
, Issue.4
, pp. 389-390
-
-
Baylor, M.S.1
Johann-Liang, R.2
-
115
-
-
20544465838
-
24-week safety and efficacy of enfuvirtide as part of an optimized ART regimen in children
-
abstract 765, 22-25 February, Boston, Massachusetts, USA
-
Wiznia A, Church J, Emmanuel P, et al. 24-week safety and efficacy of enfuvirtide as part of an optimized ART regimen in children [abstract 765]. Proceedings of the 12th Conference on Retroviruses and Opportunistic Infections (CROI); 22-25 February 2005; Boston, Massachusetts, USA
-
(2005)
Proceedings of the 12th Conference on Retroviruses and Opportunistic Infections (CROI)
-
-
Wiznia, A.1
Church, J.2
Emmanuel, P.3
-
116
-
-
0036020193
-
Safety and antiretroviral activity of chronic subcutaneous administration of T-20 in human immunodeficiency virus 1-infected children
-
Church JA, Cunningham C, Hughes M, et al. Safety and antiretroviral activity of chronic subcutaneous administration of T-20 in human immunodeficiency virus 1-infected children. Pediatr Infect Dis J 2002;21(7):653-9
-
(2002)
Pediatr Infect Dis J
, vol.21
, Issue.7
, pp. 653-659
-
-
Church, J.A.1
Cunningham, C.2
Hughes, M.3
-
117
-
-
4043094071
-
Long term tolerability and safety of enfuvirtide for human immunodeficiency virus 1-infected children
-
Church JA, Hughes M, Chen J, et al. Long term tolerability and safety of enfuvirtide for human immunodeficiency virus 1-infected children. Pediatr Infect Dis J 2004;23(8):713-8
-
(2004)
Pediatr Infect Dis J
, vol.23
, Issue.8
, pp. 713-718
-
-
Church, J.A.1
Hughes, M.2
Chen, J.3
-
118
-
-
2642553329
-
24-Week safety and efficacy of enfuvirtide as part of an optimized antiretroviral regimen in adolescents
-
abstract 929, 8-11 February, San Francisco, California, USA
-
Wiznia A, Church J, Stavola J, et al. 24-Week safety and efficacy of enfuvirtide as part of an optimized antiretroviral regimen in adolescents [abstract 929]. Proceedings of the 11th Conference on Retroviruses and Opportunistic Infections (CROI). 8-11 February 2004; San Francisco, California, USA
-
(2004)
Proceedings of the 11th Conference on Retroviruses and Opportunistic Infections (CROI)
-
-
Wiznia, A.1
Church, J.2
Stavola, J.3
-
119
-
-
52349123230
-
-
Toronto General Hospital immunodeficiency clinic. Available from:, Accessed 12 July 2008
-
Tseng A, Marr P. Drug interaction tables, Toronto General Hospital immunodeficiency clinic. Available from: http://www.tthhivclinic.com/ interact_tables.html [Accessed 12 July 2008]
-
Drug interaction tables
-
-
Tseng, A.1
Marr, P.2
-
120
-
-
52349098356
-
-
Darunavir ethalolate (marketed as prezista) information; FDA alert. US Food and Drug Administration, 21 March 2008. Available from: http://www.fda.gov/cder/drug/infopage/darunavir/default.htm [Last accessed 5 April 2008]
-
Darunavir ethalolate (marketed as prezista) information; FDA alert. US Food and Drug Administration, 21 March 2008. Available from: http://www.fda.gov/cder/drug/infopage/darunavir/default.htm [Last accessed 5 April 2008]
-
-
-
-
121
-
-
52349099049
-
-
Aptivus prescribing information. Boehringer Ingelheim Pharmaceuticals, Inc., Oct 2007. Available from: http://bidocs.boehringer-ingelheim.com/ BIWebAccess/ViewServlet.ser?docBase=renetnt&folderPath=/ Prescribing+Information/PIs/Aptivus/10003515+US+01.pdf [Last accessed 5 April 2008]
-
Aptivus prescribing information. Boehringer Ingelheim Pharmaceuticals, Inc., Oct 2007. Available from: http://bidocs.boehringer-ingelheim.com/ BIWebAccess/ViewServlet.ser?docBase=renetnt&folderPath=/ Prescribing+Information/PIs/Aptivus/10003515+US+01.pdf [Last accessed 5 April 2008]
-
-
-
-
122
-
-
52349112151
-
-
Vingerhoets J, Peeters M, Corbett C, et al. Effect of baseline resistance on the virologic response to a novel NNRTI, TMC125, in patients with extensive NNRTI and PI resistance: analysis of study TMCI25-223 [abstract 154]. Proceedings of the 13th Conference on Retroviruses and Opportunistic Infections (CROI); 5-8 February 2006; Denver, Colorado, USA
-
Vingerhoets J, Peeters M, Corbett C, et al. Effect of baseline resistance on the virologic response to a novel NNRTI, TMC125, in patients with extensive NNRTI and PI resistance: analysis of study TMCI25-223 [abstract 154]. Proceedings of the 13th Conference on Retroviruses and Opportunistic Infections (CROI); 5-8 February 2006; Denver, Colorado, USA
-
-
-
-
123
-
-
42549140294
-
Impact of baseline NNRTI mutations on the virological response to TMC125 in the phase III clinical trials DUET-1 and DUET-2 [abstract 32]
-
12-16 June, Barbados, West Indies
-
Vingerhoets J, Buelens A, Peeters M, et al. Impact of baseline NNRTI mutations on the virological response to TMC125 in the phase III clinical trials DUET-1 and DUET-2 [abstract 32]. Proceedings of the 16th international HIV drug resistance workshop; 12-16 June 2007; Barbados, West Indies
-
(2007)
Proceedings of the 16th international HIV drug resistance workshop
-
-
Vingerhoets, J.1
Buelens, A.2
Peeters, M.3
-
124
-
-
33746966338
-
Significant decrease in TMC125 exposures when co-adminiscered with tipranavir boosted with ritonavir in healthy subjects
-
abstract 583, 5-8 February, Denver, Colorado, USA
-
Scholler M, Kraft M, Hoetelmans R, et al. Significant decrease in TMC125 exposures when co-adminiscered with tipranavir boosted with ritonavir in healthy subjects [abstract 583]. Proceedings of the 13th Conference on Retroviruses and Opportunistic Infections (CROI); 5-8 February 2006; Denver, Colorado, USA
-
(2006)
Proceedings of the 13th Conference on Retroviruses and Opportunistic Infections (CROI)
-
-
Scholler, M.1
Kraft, M.2
Hoetelmans, R.3
-
125
-
-
50949112147
-
Outcomes of multidrug-resistant patients switched from enfuvirtide to raltegravir within a virologically suppressive regimen
-
Harris M, Larsen G, Montaner JSG. Outcomes of multidrug-resistant patients switched from enfuvirtide to raltegravir within a virologically suppressive regimen. AIDS 2008;22(10):1224-6
-
(2008)
AIDS
, vol.22
, Issue.10
, pp. 1224-1226
-
-
Harris, M.1
Larsen, G.2
Montaner, J.S.G.3
-
126
-
-
52349107294
-
-
Raltegravir substitution for enfuvirtide in patients suffering from injection site reactions (ISRs): the Raleve pilot study, 2008. Available from: http://clinicaltrials.gov/ct2/show/ NCT00523237?intr=%22Enfuvirtide%22&rank=37 [Last accessed 8 June 2008]
-
Raltegravir substitution for enfuvirtide in patients suffering from injection site reactions (ISRs): the Raleve pilot study, 2008. Available from: http://clinicaltrials.gov/ct2/show/ NCT00523237?intr=%22Enfuvirtide%22&rank=37 [Last accessed 8 June 2008]
-
-
-
-
127
-
-
52349118733
-
-
Efficacy and tolerance of the switch from enfuvirtine to raltegravir in antiretroviral therapy regimen in HIV patients with undetectable viral load EASIER, Available from:, Last accessed 8 June 2008
-
Efficacy and tolerance of the switch from enfuvirtine to raltegravir in antiretroviral therapy regimen in HIV patients with undetectable viral load (EASIER). Available from: http://clinicaltrials.gov/ct2/show/ NCT00454337?term=easier+study&rank=1 [Last accessed 8 June 2008]
-
-
-
-
130
-
-
27644510382
-
Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity
-
Dorr P, Westby M, Dobbs S, et al. Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity. Antimicrob Agents Chemother 2005;49(11):4721-32
-
(2005)
Antimicrob Agents Chemother
, vol.49
, Issue.11
, pp. 4721-4732
-
-
Dorr, P.1
Westby, M.2
Dobbs, S.3
-
131
-
-
33745581733
-
GlaxoSmithKline ends aplaviroc trials
-
Crabb C. GlaxoSmithKline ends aplaviroc trials. AIDS 2006;20(5):641
-
(2006)
AIDS
, vol.20
, Issue.5
, pp. 641
-
-
Crabb, C.1
-
133
-
-
34347379935
-
Phase 2 study of the safety and efficacy of vicriviroc, a CCR5 inhibitor, in HIV-1-infected, treatment-experienced patients: AIDS clinical trials group 5211
-
Gulick RM, Su Z, Flexner C, et al. Phase 2 study of the safety and efficacy of vicriviroc, a CCR5 inhibitor, in HIV-1-infected, treatment-experienced patients: AIDS clinical trials group 5211. J Infect Dis 2007;196(2):304-12
-
(2007)
J Infect Dis
, vol.196
, Issue.2
, pp. 304-312
-
-
Gulick, R.M.1
Su, Z.2
Flexner, C.3
-
134
-
-
33747120483
-
Characterization of Gp41 evolution in a large cohort of HIV-1-infected patients receiving long-term T-20 treatment as a single active drug
-
abstract 596, 5-8 Feb, Denver, Colorado, USA
-
Aquaro S, Svicher V, D'Arrigo R, et al. Characterization of Gp41 evolution in a large cohort of HIV-1-infected patients receiving long-term T-20 treatment as a single active drug [abstract 596]. Proceedings of the 13th Conference on Retroviruses and Opportunistic Infections (CROI); 5-8 Feb 2006; Denver, Colorado, USA
-
(2006)
Proceedings of the 13th Conference on Retroviruses and Opportunistic Infections (CROI)
-
-
Aquaro, S.1
Svicher, V.2
D'Arrigo, R.3
|