-
1
-
-
0037237596
-
Human insulin resistance: The role of glucocorticoids
-
Reynolds RM, Walker BR. Human insulin resistance: the role of glucocorticoids. Diabetes Obes Metab 2003; 5: 5-12.
-
(2003)
Diabetes Obes. Metab.
, vol.5
, pp. 5-12
-
-
Reynolds, R.M.1
Walker, B.R.2
-
2
-
-
0030866606
-
Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse islets
-
Lambillotte C, Gilon P, Henquin JC. Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse islets. J Clin Invest 1997; 99: 414-423.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 414-423
-
-
Lambillotte, C.1
Gilon, P.2
Henquin, J.C.3
-
3
-
-
0035107072
-
The effects of dexamethasone on insulin release and biosynthesis are dependent on the dose and duration of treatment
-
Jeong IK, Oh SH, Kim BJ,, et al. The effects of dexamethasone on insulin release and biosynthesis are dependent on the dose and duration of treatment. Diabetes Res Clin Pract 2001; 51: 163-171.
-
(2001)
Diabetes Res. Clin. Pract.
, vol.51
, pp. 163-171
-
-
Jeong, I.K.1
Oh, S.H.2
Kim, B.J.3
-
4
-
-
0343415138
-
Dexametnasone-induced changes in FAD-glycerophosphate dehydrogenase mRNA, content and activity, and insulin release in human pancreatic islets
-
Fabregat ME, Fernandez-Alvarez J, Franco C, Malaisse WJ, Gomis R. Dexametnasone-induced changes in FAD-glycerophosphate dehydrogenase mRNA, content and activity, and insulin release in human pancreatic islets. Diabetes Nutr Metab 1999; 12: 388-393.
-
(1999)
Diabetes Nutr. Metab.
, vol.12
, pp. 388-393
-
-
Fabregat, M.E.1
Fernandez-Alvarez, J.2
Franco, C.3
Malaisse, W.J.4
Gomis, R.5
-
5
-
-
0035111321
-
Beta cell adaptation to dexamethasone-induced insulin resistance in rats involves increased glucose responsiveness but not glucose effectiveness
-
Karlsson S, Ostlund B, Myrsen-Axcrona U, Sundler F, Ahren B. Beta cell adaptation to dexamethasone-induced insulin resistance in rats involves increased glucose responsiveness but not glucose effectiveness. Pancreas 2001; 22: 148-156.
-
(2001)
Pancreas
, vol.22
, pp. 148-156
-
-
Karlsson, S.1
Ostlund, B.2
Myrsen-Axcrona, U.3
Sundler, F.4
Ahren, B.5
-
6
-
-
85047683614
-
Minireview: 11β-hydroxysteroid dehydrogenase type 1- a tissue- specific amplifier of glucocorticoid action
-
Seckl JR, Walker BR. Minireview: 11β-hydroxysteroid dehydrogenase type 1- a tissue- specific amplifier of glucocorticoid action. Endocrinology 2001; 142: 1371-1376.
-
(2001)
Endocrinology
, vol.142
, pp. 1371-1376
-
-
Seckl, J.R.1
Walker, B.R.2
-
7
-
-
0034634085
-
Type 11β -hydroxysteroid dehydrogenase mediates glucocorticoid activation and insulin release in pancreatic islets
-
Davani B, Khan A, Hult M, et al. Type 11β -hydroxysteroid dehydrogenase mediates glucocorticoid activation and insulin release in pancreatic islets. J Biol Chem 2000; 275: 34841-34844.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34841-34844
-
-
Davani, B.1
Khan, A.2
Hult, M.3
-
8
-
-
0028839840
-
Carbenoxolone increases hepatic insulin sensitivity in man: A novel role for 11-16 oxosteroid reductase in enhancing glucocorticoid receptor activation
-
Walker BR, Connacher AA, Lindsay RM, Webb DJ, Edwards CR. Carbenoxolone increases hepatic insulin sensitivity in man: a novel role for 11-16 oxosteroid reductase in enhancing glucocorticoid receptor activation. J Clin Endocrinol Metab 1995; 80: 3155-3159.
-
(1995)
J. Clin. Endocrinol. Metab.
, vol.80
, pp. 3155-3159
-
-
Walker, B.R.1
Connacher, A.A.2
Lindsay, R.M.3
Webb, D.J.4
Edwards, C.R.5
-
9
-
-
0036432995
-
Selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 decreases blood glucose concentrations in hyperglycaemic mice
-
Alberts P, Engblom L, Edling N, et al. Selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 decreases blood glucose concentrations in hyperglycaemic mice. Diabetologia 2002; 45: 1528-1532.
-
(2002)
Diabetologia
, vol.45
, pp. 1528-1532
-
-
Alberts, P.1
Engblom, L.2
Edling, N.3
-
10
-
-
0242468543
-
Selective inhibition of 11β-hydroxysteroid dehydrogenaSe type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains
-
Alberts P, Nilsson C, Selen G, et al. Selective inhibition of 11β-hydroxysteroid dehydrogenaSe type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains. Endocrinology 2003; 144:4755-4762.
-
(2003)
Endocrinology
, vol.144
, pp. 4755-4762
-
-
Alberts, P.1
Nilsson, C.2
Selen, G.3
-
11
-
-
0037194658
-
Arylsulfonamidothiazoles as a new class of potential antidiabetic drugs. Discovery of potent and selective inhibitors of the 11β-hydroxysteroid dehydrogenase type 1
-
Barf T, Vallgårda J, Emond R, et al. Arylsulfonamidothiazoles as a new class of potential antidiabetic drugs. Discovery of potent and selective inhibitors of the 11β-hydroxysteroid dehydrogenase type 1. J Med Chem 2002; 45: 3813-3815.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 3813-3815
-
-
Barf, T.1
Vallgårda, J.2
Emond, R.3
-
12
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
13
-
-
0027172931
-
Glucose-induced amplitude regulation of pulsatile insulin secretion from individual pancreatic islets
-
Bergsten P, Hellman B. Glucose-induced amplitude regulation of pulsatile insulin secretion from individual pancreatic islets. Diabetes 1993; 42: 670-674.
-
(1993)
Diabetes
, vol.42
, pp. 670-674
-
-
Bergsten, P.1
Hellman, B.2
-
14
-
-
0036459823
-
Contribution of glycolytic and mitochondrial pathways in glucose-induced changes in islet respiration and insulin secretion
-
Ortsäter H, Liss P, Åkerman KE, Bergsten P. Contribution of glycolytic and mitochondrial pathways in glucose-induced changes in islet respiration and insulin secretion. Pflugers Arch 2002; 444: 506-512.
-
(2002)
Pflugers Arch.
, vol.444
, pp. 506-512
-
-
Ortsäter, H.1
Liss, P.2
Åkerman, K.E.3
Bergsten, P.4
-
16
-
-
0033570887
-
Steroid and nuclear receptors. Villefranche-sur-Mer, France, May 25-27, 1999
-
Di Croce L, Okret S, Kersten S, et al. Steroid and nuclear receptors. Villefranche-sur-Mer, France, May 25-27, 1999. Embo J 1999; 18: 6201-6210.
-
(1999)
Embo. J.
, vol.18
, pp. 6201-6210
-
-
Di Croce, L.1
Okret, S.2
Kersten, S.3
-
17
-
-
0036817372
-
Dialyzable free cortisol after stimulation with Synacthen
-
Vogeser M, Briege J, Zachoval R. Dialyzable free cortisol after stimulation with Synacthen. Clin Biochem 2002; 35: 539-543.
-
(2002)
Clin. Biochem.
, vol.35
, pp. 539-543
-
-
Vogeser, M.1
Briege, J.2
Zachoval, R.3
-
18
-
-
0020022809
-
The serum transport of steroid hormones
-
Siiteri PK, Murai JT, Hammond GL, Nisker JA, Raymoure WJ, Kuhn RW. The serum transport of steroid hormones. Recent Prog Horm Res 1982; 38: 457-510.
-
(1982)
Recent Prog. Horm. Res.
, vol.38
, pp. 457-510
-
-
Siiteri, P.K.1
Murai, J.T.2
Hammond, G.L.3
Nisker, J.A.4
Raymoure, W.J.5
Kuhn, R.W.6
-
19
-
-
0026441301
-
Mineralocorticoid excess and inhibition of 11β-hydroxysteroid dehydrogenase in patients with ectopic ACTH syndrome
-
Walker BR, Campbell JC, Fraser R, Stewart PM, Edwards CR. Mineralocorticoid excess and inhibition of 11β-hydroxysteroid dehydrogenase in patients with ectopic ACTH syndrome. Clin Endocrinol (Oxf) 1992; 37: 483-492.
-
(1992)
Clin. Endocrinol. (Oxf.)
, vol.37
, pp. 483-492
-
-
Walker, B.R.1
Campbell, J.C.2
Fraser, R.3
Stewart, P.M.4
Edwards, C.R.5
-
20
-
-
0035111323
-
Intracellular regeneration of glucocorticoids by 11β-hydroxysteroid dehydrogenase (11β-HSD)-1 plays a key role in regulation of the hypothalamic-pituitary-adrenal axis: Analysis of 11β-HSD-1-deficient mice
-
Harris HJ, Kotelevtsev Y, Mullins JJ, Seckl JR, Holmes MC. Intracellular regeneration of glucocorticoids by 11β-hydroxysteroid dehydrogenase (11β-HSD)-1 plays a key role in regulation of the hypothalamic-pituitary-adrenal axis: analysis of 11β-HSD-1-deficient mice. Endocrinology 2001; 142: 114-120.
-
(2001)
Endocrinology
, vol.142
, pp. 114-120
-
-
Harris, H.J.1
Kotelevtsev, Y.2
Mullins, J.J.3
Seckl, J.R.4
Holmes, M.C.5
-
21
-
-
0026095840
-
The human gene for 11β-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization
-
Tannin GM, Agarwal AK, Monder C, New MI, White PC. The human gene for 11β-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization. J Biol Chem 1991; 266: 16653-16658.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 16653-16658
-
-
Tannin, G.M.1
Agarwal, A.K.2
Monder, C.3
New, M.I.4
White, P.C.5
-
22
-
-
0021068437
-
Diurnal rhythm for corticosterone in obese (ob/ob) diabetes (db/db) and gold-thioglucose-induced obesity in mice
-
Saito M, Bray GA. Diurnal rhythm for corticosterone in obese (ob/ob) diabetes (db/db) and gold-thioglucose-induced obesity in mice. Endocrinology 1983; 113: 2181-2185.
-
(1983)
Endocrinology
, vol.113
, pp. 2181-2185
-
-
Saito, M.1
Bray, G.A.2
-
23
-
-
0347064002
-
Increased expression and activity of 11β-HSD-1 in diabetic islets and prevention with troglitazone
-
Duplomb L, Lee Y, Wang MY, et al. Increased expression and activity of 11β-HSD-1 in diabetic islets and prevention with troglitazone. Biochem Biophys Res Commun 2004; 313: 594-599.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.313
, pp. 594-599
-
-
Duplomb, L.1
Lee, Y.2
Wang, M.Y.3
-
24
-
-
0036324073
-
Tissue-specific changes in peripheral cortisol metabolism in obese women: Increased adipose 11β-hydroxysteroid dehydrogenase type 1 activity
-
Rask E, Walker BR, Soderberg S, et al. Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11β-hydroxysteroid dehydrogenase type 1 activity. J Clin Endocrinol Metab 2002; 87: 3330-3336.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 3330-3336
-
-
Rask, E.1
Walker, B.R.2
Soderberg, S.3
-
25
-
-
1842552244
-
Regulation of 11β-HSD genes in human adipose tissue: Influence of central obesity and weight loss
-
Engeli S, Bohnke J, Feldpausch M, et al. Regulation of 11β-HSD genes in human adipose tissue: influence of central obesity and weight loss. Obes Res 2004; 12: 9-17.
-
(2004)
Obes. Res.
, vol.12
, pp. 9-17
-
-
Engeli, S.1
Bohnke, J.2
Feldpausch, M.3
-
26
-
-
0029953305
-
Effect of growth hormone, insulin and dexamethasone on 11β-hydroxysteroid dehydrogenase activity on a primary culture of rat hepatocytes
-
Liu YJ, Nakagawa Y, Nasuda K, Saegusa H, Igarashi Y. Effect of growth hormone, insulin and dexamethasone on 11β-hydroxysteroid dehydrogenase activity on a primary culture of rat hepatocytes. Life Sci 1996; 59: 227-234.
-
(1996)
Life Sci.
, vol.59
, pp. 227-234
-
-
Liu, Y.J.1
Nakagawa, Y.2
Nasuda, K.3
Saegusa, H.4
Igarashi, Y.5
-
27
-
-
0035000828
-
Regulation of glucocorticoid receptor alpha and beta isoforms and type 11β-hydroxysteroid dehydrogenase expression in human skeletal muscle cells: A key role in the pathogenesis of insulin resistance?
-
Whorwood CB, Donovan SJ, Wood PJ, Phillips DI. Regulation of glucocorticoid receptor alpha and beta isoforms and type 11β-hydroxysteroid dehydrogenase expression in human skeletal muscle cells: a key role in the pathogenesis of insulin resistance? J Clin Endocrinol Metab 2001; 86: 2296-2308.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 2296-2308
-
-
Whorwood, C.B.1
Donovan, S.J.2
Wood, P.J.3
Phillips, D.I.4
-
28
-
-
0036838927
-
Intracrine induction of 11β-hydroxysteroid dehydrogenase type 1 expression by glucocorticoid potentiates prostaglandin production in the human chorionic trophoblast
-
Sun K, He P, Yang K. Intracrine induction of 11β-hydroxysteroid dehydrogenase type 1 expression by glucocorticoid potentiates prostaglandin production in the human chorionic trophoblast. Biol Reprod 2002; 67: 1450-1455.
-
(2002)
Biol. Reprod.
, vol.67
, pp. 1450-1455
-
-
Sun, K.1
He, P.2
Yang, K.3
-
29
-
-
0033000632
-
Tissue- and temporal-specific regulation of 11β-hydroxysteroid dehydrogenase type 1 by glucocorticoids in vivo
-
Jamieson PM, Chapman KE, Seckl JR. Tissue- and temporal-specific regulation of 11β-hydroxysteroid dehydrogenase type 1 by glucocorticoids in vivo. J Steroid Biochem Mol Biol 1999; 68: 245-250.
-
(1999)
J. Steroid Biochem. Mol. Biol.
, vol.68
, pp. 245-250
-
-
Jamieson, P.M.1
Chapman, K.E.2
Seckl, J.R.3
-
30
-
-
0023121392
-
Increased sensitivity of the genetically obese mouse to corticosterone
-
Tokuyama K, Himms-Hagen J. Increased sensitivity of the genetically obese mouse to corticosterone. Am J Physiol 1987; 252: E202-E208.
-
(1987)
Am. J. Physiol.
, vol.252
-
-
Tokuyama, K.1
Himms-Hagen, J.2
-
31
-
-
0031051692
-
RU486 (mifepristone): Mechanisms of action and clinical uses
-
Cadepond F, Ulmann A, Baulieu EE. RU486 (mifepristone): mechanisms of action and clinical uses. Annu Rev Med 1997; 48: 129-156.
-
(1997)
Annu. Rev. Med.
, vol.48
, pp. 129-156
-
-
Cadepond, F.1
Ulmann, A.2
Baulieu, E.E.3
-
32
-
-
0021335723
-
Direct effect of gonadal and contraceptive steroids on insulin release from mouse pancreatic islets in organ culture
-
Nielsen JH. Direct effect of gonadal and contraceptive steroids on insulin release from mouse pancreatic islets in organ culture. Acta Endocrinol (Copenh) 1984; 105: 245-250.
-
(1984)
Acta Endocrinol. (Copenh.)
, vol.105
, pp. 245-250
-
-
Nielsen, J.H.1
-
33
-
-
0025247084
-
Immunocytochemical localization of progesterone receptors in endocrine cells of the human pancreas
-
Doglioni C, Gambacorta M, Zamboni G, Coggi G, Viale G. Immunocytochemical localization of progesterone receptors in endocrine cells of the human pancreas. Am J Pathol 1990; 137: 999-1005.
-
(1990)
Am. J. Pathol.
, vol.137
, pp. 999-1005
-
-
Doglioni, C.1
Gambacorta, M.2
Zamboni, G.3
Coggi, G.4
Viale, G.5
-
34
-
-
0031839468
-
Increased glucocorticoid sensitivity in islet beta-cells: Effects on glucose 6-phosphatase, glucose cycling and insulin release
-
Ling ZC, Khan A, Delauny F, et al. Increased glucocorticoid sensitivity in islet beta-cells: effects on glucose 6-phosphatase, glucose cycling and insulin release. Diabetologia 1998; 41: 634-639.
-
(1998)
Diabetologia
, vol.41
, pp. 634-639
-
-
Ling, Z.C.1
Khan, A.2
Delauny, F.3
-
35
-
-
0031033882
-
Dexamethasone induces posttranslational degradation of GLUT2 and inhibition of insulin secretion in isolated pancreatic βcells. Comparison with the effects of fatty acids
-
Gremlich S, Roduit R, Thorens B. Dexamethasone induces posttranslational degradation of GLUT2 and inhibition of insulin secretion in isolated pancreatic βcells. Comparison with the effects of fatty acids. J Biol Chem 1997; 272: 3216-3222.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3216-3222
-
-
Gremlich, S.1
Roduit, R.2
Thorens, B.3
-
36
-
-
0032959852
-
The human insulin gene contains multiple transcriptional elements that respond to glucocorticoids
-
Fernandez-Mejia C, Medina-Martinez O, Martinez-Perez L, Goodman PA. The human insulin gene contains multiple transcriptional elements that respond to glucocorticoids. Pancreas 1999; 18: 336-341.
-
(1999)
Pancreas
, vol.18
, pp. 336-341
-
-
Fernandez-Mejia, C.1
Medina-Martinez, O.2
Martinez-Perez, L.3
Goodman, P.A.4
-
37
-
-
0035860335
-
Altered expression of HES-1, BETA2/NeuroD, and PDX-1 is involved in impaired insulin synthesis induced by glucocorticoids in HIT-T15 cells
-
Shinozuka Y, Okada M, Oki T, et al. Altered expression of HES-1, BETA2/NeuroD, and PDX-1 is involved in impaired insulin synthesis induced by glucocorticoids in HIT-T15 cells. Biochem Biophys Res Commun 2001; 287: 229-235.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.287
, pp. 229-235
-
-
Shinozuka, Y.1
Okada, M.2
Oki, T.3
-
38
-
-
0038408269
-
Histochemical studies on glucose-6-phosphatase, adenosine triphosphatase and amylo phosphorylase in the pancreatic islets of normal and obese-hyperglycaemic mice
-
Hellman B, Hellerström C. Histochemical studies on glucose-6-phosphatase, adenosine triphosphatase and amylo phosphorylase in the pancreatic islets of normal and obese-hyperglycaemic mice. Acta Endocrinologica 1962; 39: 474-482.
-
(1962)
Acta Endocrinologica
, vol.39
, pp. 474-482
-
-
Hellman, B.1
Hellerström, C.2
-
39
-
-
0014576715
-
Presence, induction and possible role of glucose 6-phosphatase in mammalian pancreatic islets
-
Täljedal I. Presence, induction and possible role of glucose 6-phosphatase in mammalian pancreatic islets. Biochem J 1969; 114: 387-394.
-
(1969)
Biochem. J.
, vol.114
, pp. 387-394
-
-
Täljedal, I.1
|