메뉴 건너뛰기




Volumn 21, Issue 4, 2005, Pages 359-366

Regulation of 11β-hydroxysteroid dehydrogenase type 1 and glucose-stimulated insulin secretion in pancreatic islets of langerhans

Author keywords

11 hydroxysteroid dehydrogenase; Glucocorticoids; Insulin release; Pancreatic islets

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; CORTICOSTERONE; DEHYDROCORTICOSTERONE; GLUCOCORTICOID RECEPTOR ANTAGONIST; GLUCOSE; INSULIN; MESSENGER RNA;

EID: 21744451489     PISSN: 15207552     EISSN: None     Source Type: Journal    
DOI: 10.1002/dmrr.525     Document Type: Article
Times cited : (26)

References (39)
  • 1
    • 0037237596 scopus 로고    scopus 로고
    • Human insulin resistance: The role of glucocorticoids
    • Reynolds RM, Walker BR. Human insulin resistance: the role of glucocorticoids. Diabetes Obes Metab 2003; 5: 5-12.
    • (2003) Diabetes Obes. Metab. , vol.5 , pp. 5-12
    • Reynolds, R.M.1    Walker, B.R.2
  • 2
    • 0030866606 scopus 로고    scopus 로고
    • Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse islets
    • Lambillotte C, Gilon P, Henquin JC. Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse islets. J Clin Invest 1997; 99: 414-423.
    • (1997) J. Clin. Invest. , vol.99 , pp. 414-423
    • Lambillotte, C.1    Gilon, P.2    Henquin, J.C.3
  • 3
    • 0035107072 scopus 로고    scopus 로고
    • The effects of dexamethasone on insulin release and biosynthesis are dependent on the dose and duration of treatment
    • Jeong IK, Oh SH, Kim BJ,, et al. The effects of dexamethasone on insulin release and biosynthesis are dependent on the dose and duration of treatment. Diabetes Res Clin Pract 2001; 51: 163-171.
    • (2001) Diabetes Res. Clin. Pract. , vol.51 , pp. 163-171
    • Jeong, I.K.1    Oh, S.H.2    Kim, B.J.3
  • 4
    • 0343415138 scopus 로고    scopus 로고
    • Dexametnasone-induced changes in FAD-glycerophosphate dehydrogenase mRNA, content and activity, and insulin release in human pancreatic islets
    • Fabregat ME, Fernandez-Alvarez J, Franco C, Malaisse WJ, Gomis R. Dexametnasone-induced changes in FAD-glycerophosphate dehydrogenase mRNA, content and activity, and insulin release in human pancreatic islets. Diabetes Nutr Metab 1999; 12: 388-393.
    • (1999) Diabetes Nutr. Metab. , vol.12 , pp. 388-393
    • Fabregat, M.E.1    Fernandez-Alvarez, J.2    Franco, C.3    Malaisse, W.J.4    Gomis, R.5
  • 5
    • 0035111321 scopus 로고    scopus 로고
    • Beta cell adaptation to dexamethasone-induced insulin resistance in rats involves increased glucose responsiveness but not glucose effectiveness
    • Karlsson S, Ostlund B, Myrsen-Axcrona U, Sundler F, Ahren B. Beta cell adaptation to dexamethasone-induced insulin resistance in rats involves increased glucose responsiveness but not glucose effectiveness. Pancreas 2001; 22: 148-156.
    • (2001) Pancreas , vol.22 , pp. 148-156
    • Karlsson, S.1    Ostlund, B.2    Myrsen-Axcrona, U.3    Sundler, F.4    Ahren, B.5
  • 6
    • 85047683614 scopus 로고    scopus 로고
    • Minireview: 11β-hydroxysteroid dehydrogenase type 1- a tissue- specific amplifier of glucocorticoid action
    • Seckl JR, Walker BR. Minireview: 11β-hydroxysteroid dehydrogenase type 1- a tissue- specific amplifier of glucocorticoid action. Endocrinology 2001; 142: 1371-1376.
    • (2001) Endocrinology , vol.142 , pp. 1371-1376
    • Seckl, J.R.1    Walker, B.R.2
  • 7
    • 0034634085 scopus 로고    scopus 로고
    • Type 11β -hydroxysteroid dehydrogenase mediates glucocorticoid activation and insulin release in pancreatic islets
    • Davani B, Khan A, Hult M, et al. Type 11β -hydroxysteroid dehydrogenase mediates glucocorticoid activation and insulin release in pancreatic islets. J Biol Chem 2000; 275: 34841-34844.
    • (2000) J. Biol. Chem. , vol.275 , pp. 34841-34844
    • Davani, B.1    Khan, A.2    Hult, M.3
  • 8
    • 0028839840 scopus 로고
    • Carbenoxolone increases hepatic insulin sensitivity in man: A novel role for 11-16 oxosteroid reductase in enhancing glucocorticoid receptor activation
    • Walker BR, Connacher AA, Lindsay RM, Webb DJ, Edwards CR. Carbenoxolone increases hepatic insulin sensitivity in man: a novel role for 11-16 oxosteroid reductase in enhancing glucocorticoid receptor activation. J Clin Endocrinol Metab 1995; 80: 3155-3159.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 3155-3159
    • Walker, B.R.1    Connacher, A.A.2    Lindsay, R.M.3    Webb, D.J.4    Edwards, C.R.5
  • 9
    • 0036432995 scopus 로고    scopus 로고
    • Selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 decreases blood glucose concentrations in hyperglycaemic mice
    • Alberts P, Engblom L, Edling N, et al. Selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 decreases blood glucose concentrations in hyperglycaemic mice. Diabetologia 2002; 45: 1528-1532.
    • (2002) Diabetologia , vol.45 , pp. 1528-1532
    • Alberts, P.1    Engblom, L.2    Edling, N.3
  • 10
    • 0242468543 scopus 로고    scopus 로고
    • Selective inhibition of 11β-hydroxysteroid dehydrogenaSe type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains
    • Alberts P, Nilsson C, Selen G, et al. Selective inhibition of 11β-hydroxysteroid dehydrogenaSe type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains. Endocrinology 2003; 144:4755-4762.
    • (2003) Endocrinology , vol.144 , pp. 4755-4762
    • Alberts, P.1    Nilsson, C.2    Selen, G.3
  • 11
    • 0037194658 scopus 로고    scopus 로고
    • Arylsulfonamidothiazoles as a new class of potential antidiabetic drugs. Discovery of potent and selective inhibitors of the 11β-hydroxysteroid dehydrogenase type 1
    • Barf T, Vallgårda J, Emond R, et al. Arylsulfonamidothiazoles as a new class of potential antidiabetic drugs. Discovery of potent and selective inhibitors of the 11β-hydroxysteroid dehydrogenase type 1. J Med Chem 2002; 45: 3813-3815.
    • (2002) J. Med. Chem. , vol.45 , pp. 3813-3815
    • Barf, T.1    Vallgårda, J.2    Emond, R.3
  • 12
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 13
    • 0027172931 scopus 로고
    • Glucose-induced amplitude regulation of pulsatile insulin secretion from individual pancreatic islets
    • Bergsten P, Hellman B. Glucose-induced amplitude regulation of pulsatile insulin secretion from individual pancreatic islets. Diabetes 1993; 42: 670-674.
    • (1993) Diabetes , vol.42 , pp. 670-674
    • Bergsten, P.1    Hellman, B.2
  • 14
    • 0036459823 scopus 로고    scopus 로고
    • Contribution of glycolytic and mitochondrial pathways in glucose-induced changes in islet respiration and insulin secretion
    • Ortsäter H, Liss P, Åkerman KE, Bergsten P. Contribution of glycolytic and mitochondrial pathways in glucose-induced changes in islet respiration and insulin secretion. Pflugers Arch 2002; 444: 506-512.
    • (2002) Pflugers Arch. , vol.444 , pp. 506-512
    • Ortsäter, H.1    Liss, P.2    Åkerman, K.E.3    Bergsten, P.4
  • 16
    • 0033570887 scopus 로고    scopus 로고
    • Steroid and nuclear receptors. Villefranche-sur-Mer, France, May 25-27, 1999
    • Di Croce L, Okret S, Kersten S, et al. Steroid and nuclear receptors. Villefranche-sur-Mer, France, May 25-27, 1999. Embo J 1999; 18: 6201-6210.
    • (1999) Embo. J. , vol.18 , pp. 6201-6210
    • Di Croce, L.1    Okret, S.2    Kersten, S.3
  • 17
    • 0036817372 scopus 로고    scopus 로고
    • Dialyzable free cortisol after stimulation with Synacthen
    • Vogeser M, Briege J, Zachoval R. Dialyzable free cortisol after stimulation with Synacthen. Clin Biochem 2002; 35: 539-543.
    • (2002) Clin. Biochem. , vol.35 , pp. 539-543
    • Vogeser, M.1    Briege, J.2    Zachoval, R.3
  • 19
    • 0026441301 scopus 로고
    • Mineralocorticoid excess and inhibition of 11β-hydroxysteroid dehydrogenase in patients with ectopic ACTH syndrome
    • Walker BR, Campbell JC, Fraser R, Stewart PM, Edwards CR. Mineralocorticoid excess and inhibition of 11β-hydroxysteroid dehydrogenase in patients with ectopic ACTH syndrome. Clin Endocrinol (Oxf) 1992; 37: 483-492.
    • (1992) Clin. Endocrinol. (Oxf.) , vol.37 , pp. 483-492
    • Walker, B.R.1    Campbell, J.C.2    Fraser, R.3    Stewart, P.M.4    Edwards, C.R.5
  • 20
    • 0035111323 scopus 로고    scopus 로고
    • Intracellular regeneration of glucocorticoids by 11β-hydroxysteroid dehydrogenase (11β-HSD)-1 plays a key role in regulation of the hypothalamic-pituitary-adrenal axis: Analysis of 11β-HSD-1-deficient mice
    • Harris HJ, Kotelevtsev Y, Mullins JJ, Seckl JR, Holmes MC. Intracellular regeneration of glucocorticoids by 11β-hydroxysteroid dehydrogenase (11β-HSD)-1 plays a key role in regulation of the hypothalamic-pituitary-adrenal axis: analysis of 11β-HSD-1-deficient mice. Endocrinology 2001; 142: 114-120.
    • (2001) Endocrinology , vol.142 , pp. 114-120
    • Harris, H.J.1    Kotelevtsev, Y.2    Mullins, J.J.3    Seckl, J.R.4    Holmes, M.C.5
  • 21
    • 0026095840 scopus 로고
    • The human gene for 11β-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization
    • Tannin GM, Agarwal AK, Monder C, New MI, White PC. The human gene for 11β-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization. J Biol Chem 1991; 266: 16653-16658.
    • (1991) J. Biol. Chem. , vol.266 , pp. 16653-16658
    • Tannin, G.M.1    Agarwal, A.K.2    Monder, C.3    New, M.I.4    White, P.C.5
  • 22
    • 0021068437 scopus 로고
    • Diurnal rhythm for corticosterone in obese (ob/ob) diabetes (db/db) and gold-thioglucose-induced obesity in mice
    • Saito M, Bray GA. Diurnal rhythm for corticosterone in obese (ob/ob) diabetes (db/db) and gold-thioglucose-induced obesity in mice. Endocrinology 1983; 113: 2181-2185.
    • (1983) Endocrinology , vol.113 , pp. 2181-2185
    • Saito, M.1    Bray, G.A.2
  • 23
    • 0347064002 scopus 로고    scopus 로고
    • Increased expression and activity of 11β-HSD-1 in diabetic islets and prevention with troglitazone
    • Duplomb L, Lee Y, Wang MY, et al. Increased expression and activity of 11β-HSD-1 in diabetic islets and prevention with troglitazone. Biochem Biophys Res Commun 2004; 313: 594-599.
    • (2004) Biochem. Biophys. Res. Commun. , vol.313 , pp. 594-599
    • Duplomb, L.1    Lee, Y.2    Wang, M.Y.3
  • 24
    • 0036324073 scopus 로고    scopus 로고
    • Tissue-specific changes in peripheral cortisol metabolism in obese women: Increased adipose 11β-hydroxysteroid dehydrogenase type 1 activity
    • Rask E, Walker BR, Soderberg S, et al. Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11β-hydroxysteroid dehydrogenase type 1 activity. J Clin Endocrinol Metab 2002; 87: 3330-3336.
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 3330-3336
    • Rask, E.1    Walker, B.R.2    Soderberg, S.3
  • 25
    • 1842552244 scopus 로고    scopus 로고
    • Regulation of 11β-HSD genes in human adipose tissue: Influence of central obesity and weight loss
    • Engeli S, Bohnke J, Feldpausch M, et al. Regulation of 11β-HSD genes in human adipose tissue: influence of central obesity and weight loss. Obes Res 2004; 12: 9-17.
    • (2004) Obes. Res. , vol.12 , pp. 9-17
    • Engeli, S.1    Bohnke, J.2    Feldpausch, M.3
  • 26
    • 0029953305 scopus 로고    scopus 로고
    • Effect of growth hormone, insulin and dexamethasone on 11β-hydroxysteroid dehydrogenase activity on a primary culture of rat hepatocytes
    • Liu YJ, Nakagawa Y, Nasuda K, Saegusa H, Igarashi Y. Effect of growth hormone, insulin and dexamethasone on 11β-hydroxysteroid dehydrogenase activity on a primary culture of rat hepatocytes. Life Sci 1996; 59: 227-234.
    • (1996) Life Sci. , vol.59 , pp. 227-234
    • Liu, Y.J.1    Nakagawa, Y.2    Nasuda, K.3    Saegusa, H.4    Igarashi, Y.5
  • 27
    • 0035000828 scopus 로고    scopus 로고
    • Regulation of glucocorticoid receptor alpha and beta isoforms and type 11β-hydroxysteroid dehydrogenase expression in human skeletal muscle cells: A key role in the pathogenesis of insulin resistance?
    • Whorwood CB, Donovan SJ, Wood PJ, Phillips DI. Regulation of glucocorticoid receptor alpha and beta isoforms and type 11β-hydroxysteroid dehydrogenase expression in human skeletal muscle cells: a key role in the pathogenesis of insulin resistance? J Clin Endocrinol Metab 2001; 86: 2296-2308.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 2296-2308
    • Whorwood, C.B.1    Donovan, S.J.2    Wood, P.J.3    Phillips, D.I.4
  • 28
    • 0036838927 scopus 로고    scopus 로고
    • Intracrine induction of 11β-hydroxysteroid dehydrogenase type 1 expression by glucocorticoid potentiates prostaglandin production in the human chorionic trophoblast
    • Sun K, He P, Yang K. Intracrine induction of 11β-hydroxysteroid dehydrogenase type 1 expression by glucocorticoid potentiates prostaglandin production in the human chorionic trophoblast. Biol Reprod 2002; 67: 1450-1455.
    • (2002) Biol. Reprod. , vol.67 , pp. 1450-1455
    • Sun, K.1    He, P.2    Yang, K.3
  • 29
    • 0033000632 scopus 로고    scopus 로고
    • Tissue- and temporal-specific regulation of 11β-hydroxysteroid dehydrogenase type 1 by glucocorticoids in vivo
    • Jamieson PM, Chapman KE, Seckl JR. Tissue- and temporal-specific regulation of 11β-hydroxysteroid dehydrogenase type 1 by glucocorticoids in vivo. J Steroid Biochem Mol Biol 1999; 68: 245-250.
    • (1999) J. Steroid Biochem. Mol. Biol. , vol.68 , pp. 245-250
    • Jamieson, P.M.1    Chapman, K.E.2    Seckl, J.R.3
  • 30
    • 0023121392 scopus 로고
    • Increased sensitivity of the genetically obese mouse to corticosterone
    • Tokuyama K, Himms-Hagen J. Increased sensitivity of the genetically obese mouse to corticosterone. Am J Physiol 1987; 252: E202-E208.
    • (1987) Am. J. Physiol. , vol.252
    • Tokuyama, K.1    Himms-Hagen, J.2
  • 31
    • 0031051692 scopus 로고    scopus 로고
    • RU486 (mifepristone): Mechanisms of action and clinical uses
    • Cadepond F, Ulmann A, Baulieu EE. RU486 (mifepristone): mechanisms of action and clinical uses. Annu Rev Med 1997; 48: 129-156.
    • (1997) Annu. Rev. Med. , vol.48 , pp. 129-156
    • Cadepond, F.1    Ulmann, A.2    Baulieu, E.E.3
  • 32
    • 0021335723 scopus 로고
    • Direct effect of gonadal and contraceptive steroids on insulin release from mouse pancreatic islets in organ culture
    • Nielsen JH. Direct effect of gonadal and contraceptive steroids on insulin release from mouse pancreatic islets in organ culture. Acta Endocrinol (Copenh) 1984; 105: 245-250.
    • (1984) Acta Endocrinol. (Copenh.) , vol.105 , pp. 245-250
    • Nielsen, J.H.1
  • 33
    • 0025247084 scopus 로고
    • Immunocytochemical localization of progesterone receptors in endocrine cells of the human pancreas
    • Doglioni C, Gambacorta M, Zamboni G, Coggi G, Viale G. Immunocytochemical localization of progesterone receptors in endocrine cells of the human pancreas. Am J Pathol 1990; 137: 999-1005.
    • (1990) Am. J. Pathol. , vol.137 , pp. 999-1005
    • Doglioni, C.1    Gambacorta, M.2    Zamboni, G.3    Coggi, G.4    Viale, G.5
  • 34
    • 0031839468 scopus 로고    scopus 로고
    • Increased glucocorticoid sensitivity in islet beta-cells: Effects on glucose 6-phosphatase, glucose cycling and insulin release
    • Ling ZC, Khan A, Delauny F, et al. Increased glucocorticoid sensitivity in islet beta-cells: effects on glucose 6-phosphatase, glucose cycling and insulin release. Diabetologia 1998; 41: 634-639.
    • (1998) Diabetologia , vol.41 , pp. 634-639
    • Ling, Z.C.1    Khan, A.2    Delauny, F.3
  • 35
    • 0031033882 scopus 로고    scopus 로고
    • Dexamethasone induces posttranslational degradation of GLUT2 and inhibition of insulin secretion in isolated pancreatic βcells. Comparison with the effects of fatty acids
    • Gremlich S, Roduit R, Thorens B. Dexamethasone induces posttranslational degradation of GLUT2 and inhibition of insulin secretion in isolated pancreatic βcells. Comparison with the effects of fatty acids. J Biol Chem 1997; 272: 3216-3222.
    • (1997) J. Biol. Chem. , vol.272 , pp. 3216-3222
    • Gremlich, S.1    Roduit, R.2    Thorens, B.3
  • 36
    • 0032959852 scopus 로고    scopus 로고
    • The human insulin gene contains multiple transcriptional elements that respond to glucocorticoids
    • Fernandez-Mejia C, Medina-Martinez O, Martinez-Perez L, Goodman PA. The human insulin gene contains multiple transcriptional elements that respond to glucocorticoids. Pancreas 1999; 18: 336-341.
    • (1999) Pancreas , vol.18 , pp. 336-341
    • Fernandez-Mejia, C.1    Medina-Martinez, O.2    Martinez-Perez, L.3    Goodman, P.A.4
  • 37
    • 0035860335 scopus 로고    scopus 로고
    • Altered expression of HES-1, BETA2/NeuroD, and PDX-1 is involved in impaired insulin synthesis induced by glucocorticoids in HIT-T15 cells
    • Shinozuka Y, Okada M, Oki T, et al. Altered expression of HES-1, BETA2/NeuroD, and PDX-1 is involved in impaired insulin synthesis induced by glucocorticoids in HIT-T15 cells. Biochem Biophys Res Commun 2001; 287: 229-235.
    • (2001) Biochem. Biophys. Res. Commun. , vol.287 , pp. 229-235
    • Shinozuka, Y.1    Okada, M.2    Oki, T.3
  • 38
    • 0038408269 scopus 로고
    • Histochemical studies on glucose-6-phosphatase, adenosine triphosphatase and amylo phosphorylase in the pancreatic islets of normal and obese-hyperglycaemic mice
    • Hellman B, Hellerström C. Histochemical studies on glucose-6-phosphatase, adenosine triphosphatase and amylo phosphorylase in the pancreatic islets of normal and obese-hyperglycaemic mice. Acta Endocrinologica 1962; 39: 474-482.
    • (1962) Acta Endocrinologica , vol.39 , pp. 474-482
    • Hellman, B.1    Hellerström, C.2
  • 39
    • 0014576715 scopus 로고
    • Presence, induction and possible role of glucose 6-phosphatase in mammalian pancreatic islets
    • Täljedal I. Presence, induction and possible role of glucose 6-phosphatase in mammalian pancreatic islets. Biochem J 1969; 114: 387-394.
    • (1969) Biochem. J. , vol.114 , pp. 387-394
    • Täljedal, I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.