Binding and penetration of methylated DNA into primary and transformed human cells

Annals of the New York Academy of Sciences

Volumn 1137, Issue , 2008, Pages 36-40

  Skvortsova, Tatyana E ^a   Vlassov, Valentin V ^a   Laktionov, Pavel P ^a  

^a INSTITUTE OF CHEMICAL BIOLOGY AND FUNDAMENTAL MEDICINE   (Russian Federation)

Author keywords

Cell surface bound DNA; DNA methylation; DNA transport; Extracellular DNA

Indexed keywords

CELL SURFACE; CELL TRANSFORMATION; CONFERENCE PAPER; DNA BINDING; DNA METHYLATION; EXTRACELLULAR SPACE; HUMAN; HUMAN CELL; NUCLEIC ACID ANALYSIS; NUCLEOTIDE SEQUENCE; TUMOR SUPPRESSOR GENE;

EID: 52249086733     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1448.033     Document Type: Conference Paper

References (13)

1. Stroun, M. et al. 2000. The origin and mechanism of circulating DNA. Ann. N. Y. Acad. Sci. 906 : 161 168.
2. Laktionov, P. et al. 2004. Free and cell surface bound nucleic acids in blood of healthy donors and breast cancer patients. Ann. N. Y. Acad. Sci. 1022 : 221 227.
3. Anker, P. 2000. Quantitative aspects of plasma/serum DNA in cancer patients. Ann. N. Y. Acad. Sci. 906 : 5 7.
4. Skvortsova, T.E. et al. 2006. DNA quantification and analysis of tumor-related gene methylation. Br. J. Cancer 94 : 1492 1495.
5. García-Olmo, D.C., et al. 2004. Circulating nucleic acids in plasma and serum (CNAPS) and its relation to stem cells and cancer metastasis: state of the issue. Histol. Histopathol. 19 : 575 583.
6. Chelobanov, B.P. et al. 2006. Proteins involved in binding and cellular uptake of nucleic acids. Biochemistry (Mosc.) 71 : 583 596.
7. Esteller, M. et al. 1999. Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients. Cancer Res. 59 : 67 70.
8. Rykova, E.Y. et al. 2004. Cell-surface-bound, tumor-derived extracellular DNA in blood of patients with breast cancer and nonmalignant tumors. Ann. N. Y. Acad. Sci. 1022 : 217 221.
9. Yao, X. et al. 2003. A methylated oligonucleotide inhibits IGF2 expression and enhances survival in a model of hepatocellular carcinoma. J. Clin. Invest. 111 : 265 273.
10. Morozkin, E.S. et al. 2004. Extracellular nucleic acids in cultures of long-term cultivated eukaryotic cells. Ann. N. Y. Acad. Sci. 1022 : 244 249.
11. Jaffe, E. et al. 1973. Culture of human endothelial cells derived from umbilical veins: identification by morphologic and immunologic criteria. J. Clin. Invest. 52 : 2745 2756.
12. van Kuppeveld, F. et al. 1994. Detection of mycoplasma contamination in cell cultures by a mycoplasma group-specific PCR. Appl. Environ. Microbiol. 60 : 149 152.
13. Chelobanov, B.P. et al. 2002. Investigation of surface oligonucleotide-binding proteins of eucaryotic cells by affinity modification with reactive oligonucleotide derivatives. Russian Chem. Bull. 7 : 1113 1119.