-
1
-
-
0025720735
-
The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
-
Angel P, Karin M. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim Biophys Acta 1072: 129-157, 1991
-
(1991)
Biochim Biophys Acta
, vol.1072
, pp. 129-157
-
-
Angel, P.1
Karin, M.2
-
2
-
-
0037472924
-
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
-
Bakkenist CJ, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421: 499-506, 2003
-
(2003)
Nature
, vol.421
, pp. 499-506
-
-
Bakkenist, C.J.1
Kastan, M.B.2
-
3
-
-
0033485261
-
Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation
-
Bulavin DV, Saito S, Hollander MC, Sakaguchi K, Anderson CW, Appella E, Fornace AJ Jr. Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation. EMBO J 18: 6845-6854, 1999
-
(1999)
EMBO J
, vol.18
, pp. 6845-6854
-
-
Bulavin, D.V.1
Saito, S.2
Hollander, M.C.3
Sakaguchi, K.4
Anderson, C.W.5
Appella, E.6
Fornace Jr., A.J.7
-
4
-
-
33747626309
-
Phorbol 12-myristate 13-acetate protects against tumor necrosis factor (TNF)-induced necrotic cell death by modulating the recruitment of TNF receptor 1-associated death domain and receptor-interacting protein into the TNF receptor 1 signaling complex: Implication for the regulatory role of protein kinase C
-
Byun HS, Park KA, Won M, Yang KJ, Shin S, Piao L, Kwak JY, Lee ZW, Park J, Seok JH, Liu ZG, Hur GM. Phorbol 12-myristate 13-acetate protects against tumor necrosis factor (TNF)-induced necrotic cell death by modulating the recruitment of TNF receptor 1-associated death domain and receptor-interacting protein into the TNF receptor 1 signaling complex: Implication for the regulatory role of protein kinase C. Mol Pharmacol 70: 1099-1108, 2006
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1099-1108
-
-
Byun, H.S.1
Park, K.A.2
Won, M.3
Yang, K.J.4
Shin, S.5
Piao, L.6
Kwak, J.Y.7
Lee, Z.W.8
Park, J.9
Seok, J.H.10
Liu, Z.G.11
Hur, G.M.12
-
5
-
-
0030597239
-
Signal transduction. Three paths to stress relief
-
Canman CE, Kastan MB. Signal transduction. Three paths to stress relief. Nature 384: 213-214, 1996
-
(1996)
Nature
, vol.384
, pp. 213-214
-
-
Canman, C.E.1
Kastan, M.B.2
-
6
-
-
0029753773
-
The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation
-
Chen YR, Wang X, Templeton D, Davis RJ, Tan TH. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation. J Biol Chem 271: 31929-31936, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 31929-31936
-
-
Chen, Y.R.1
Wang, X.2
Templeton, D.3
Davis, R.J.4
Tan, T.H.5
-
7
-
-
0037204948
-
TNF-R1 signaling: A beautiful pathway
-
Chen G, Goeddel DV. TNF-R1 signaling: a beautiful pathway. Science 296: 1634-1635, 2002.
-
(2002)
Science
, vol.296
, pp. 1634-1635
-
-
Chen, G.1
Goeddel, D.V.2
-
8
-
-
0029055812
-
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
-
Coso OA, Chiariello M, Yu JC, Teramoto H, Crespo P, Xu N, Miki T, Gutkind JS. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 81: 1137-1146, 1995
-
(1995)
Cell
, vol.81
, pp. 1137-1146
-
-
Coso, O.A.1
Chiariello, M.2
Yu, J.C.3
Teramoto, H.4
Crespo, P.5
Xu, N.6
Miki, T.7
Gutkind, J.S.8
-
9
-
-
0028329953
-
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
-
Derijard B, Hibi M, Wu IH, Barrett T, Su B, Deng T, Karin M, Davis RJ. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76: 1025-1037, 1994
-
(1994)
Cell
, vol.76
, pp. 1025-1037
-
-
Derijard, B.1
Hibi, M.2
Wu, I.H.3
Barrett, T.4
Su, B.5
Deng, T.6
Karin, M.7
Davis, R.J.8
-
10
-
-
0027363407
-
NF-kappa B activation by ultraviolet light not dependent on a nuclear signal
-
Devary Y, Rosette C, DiDonato JA, Karin M. NF-kappa B activation by ultraviolet light not dependent on a nuclear signal. Science 261: 1442-1445, 1993
-
(1993)
Science
, vol.261
, pp. 1442-1445
-
-
Devary, Y.1
Rosette, C.2
DiDonato, J.A.3
Karin, M.4
-
11
-
-
0033019306
-
Activation of c-Jun N-terminal kinase 1 by UV irradiation is inhibited by wortmannin without affecting c-iun expression
-
Fritz G, Kaina B. Activation of c-Jun N-terminal kinase 1 by UV irradiation is inhibited by wortmannin without affecting c-iun expression. Mol Cell Biol 19: 1768-1774, 1999
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1768-1774
-
-
Fritz, G.1
Kaina, B.2
-
12
-
-
0038757747
-
The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair
-
Hayakawa J, Depatie C, Ohmichi M, Mercola D. The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair. J Biol Chem 278: 20582-20592, 2003
-
(2003)
J Biol Chem
, vol.278
, pp. 20582-20592
-
-
Hayakawa, J.1
Depatie, C.2
Ohmichi, M.3
Mercola, D.4
-
14
-
-
0032748746
-
Apoptosis and drug response
-
Houghton JA. Apoptosis and drug response. Curr Opin Oncol 11: 475-481, 1999
-
(1999)
Curr Opin Oncol
, vol.11
, pp. 475-481
-
-
Houghton, J.A.1
-
15
-
-
0037382303
-
The death domain kinase RIP has an essential role in DNA damage-induced NF-kappa B activation
-
Hur GM, Lewis J, Yang Q, Lin Y, Nakano H, Nedospasov S, Liu ZG. The death domain kinase RIP has an essential role in DNA damage-induced NF-kappa B activation. Genes Dev 17: 873-882, 2003
-
(2003)
Genes Dev
, vol.17
, pp. 873-882
-
-
Hur, G.M.1
Lewis, J.2
Yang, Q.3
Lin, Y.4
Nakano, H.5
Nedospasov, S.6
Liu, Z.G.7
-
16
-
-
33748749185
-
The death domain kinase RIP has an important role in DNA damage-induced, p53-independent cell death
-
Hur GM, Kim YS, Won M, Choksi S, Liu ZG. The death domain kinase RIP has an important role in DNA damage-induced, p53-independent cell death. J Biol Chem 281: 25011-25017, 2006
-
(2006)
J Biol Chem
, vol.281
, pp. 25011-25017
-
-
Hur, G.M.1
Kim, Y.S.2
Won, M.3
Choksi, S.4
Liu, Z.G.5
-
17
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
-
Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, Takagi M, Matsumoto K, Miyazono K, Gotoh Y. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275: 90-94, 1997
-
(1997)
Science
, vol.275
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
ten Dijke, P.4
Saitoh, M.5
Moriguchi, T.6
Takagi, M.7
Matsumoto, K.8
Miyazono, K.9
Gotoh, Y.10
-
18
-
-
0036009115
-
NF-kappaB at the crossroads of life and death
-
Karin M, Lin A. NF-kappaB at the crossroads of life and death. Nat Immunol 3: 221-227, 2002
-
(2002)
Nat Immunol
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
19
-
-
0029098225
-
Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents
-
Kharbanda S, Ren R, Pandey P, Shafman TD, Feller SM, Weichselbaum RR, Kufe DW. Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents. Nature 376: 785-788, 1995
-
(1995)
Nature
, vol.376
, pp. 785-788
-
-
Kharbanda, S.1
Ren, R.2
Pandey, P.3
Shafman, T.D.4
Feller, S.M.5
Weichselbaum, R.R.6
Kufe, D.W.7
-
20
-
-
0028229012
-
The stress-activated protein kinase subfamily of c-Jun kinases
-
Kyriakis JM, Banerjee P, Nikolakaki E, Dai T, Rubie EA, Ahmad MF, Avruch J, Woodgett JR. The stress-activated protein kinase subfamily of c-Jun kinases. Nature 369: 156-160, 1994
-
(1994)
Nature
, vol.369
, pp. 156-160
-
-
Kyriakis, J.M.1
Banerjee, P.2
Nikolakaki, E.3
Dai, T.4
Rubie, E.A.5
Ahmad, M.F.6
Avruch, J.7
Woodgett, J.R.8
-
21
-
-
36849017995
-
Clinical poly (ADP-ribose) polymerase inhibitors for the treatment of cancer
-
Lewis C, Low JA. Clinical poly (ADP-ribose) polymerase inhibitors for the treatment of cancer. Curr Opin Investig Drugs 8: 1051-1056, 2007
-
(2007)
Curr Opin Investig Drugs
, vol.8
, pp. 1051-1056
-
-
Lewis, C.1
Low, J.A.2
-
22
-
-
0033821215
-
The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase
-
Lin Y, Devin A, Cook A, Keane MM, Kelliher M, Lipkowitz S, Liu ZG. The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase. Mol Cell Biol 20: 6638-6645, 2000
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6638-6645
-
-
Lin, Y.1
Devin, A.2
Cook, A.3
Keane, M.M.4
Kelliher, M.5
Lipkowitz, S.6
Liu, Z.G.7
-
23
-
-
0029856557
-
Three distinct signalling responses by murine fibroblasts to genotoxic stress
-
Liu ZG, Baskaran R, Lea-Chou ET, Wood LD, Chen Y, Karin M, Wang JY. Three distinct signalling responses by murine fibroblasts to genotoxic stress. Nature 384: 273-276, 1996
-
(1996)
Nature
, vol.384
, pp. 273-276
-
-
Liu, Z.G.1
Baskaran, R.2
Lea-Chou, E.T.3
Wood, L.D.4
Chen, Y.5
Karin, M.6
Wang, J.Y.7
-
24
-
-
0029851730
-
Role of the stress-activated/c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs
-
Osborn MT, Chambers TC. Role of the stress-activated/c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs. J Biol Chem 271: 30950-30955, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 30950-30955
-
-
Osborn, M.T.1
Chambers, T.C.2
-
25
-
-
0029796368
-
Activation of p38 mitogen-activated protein kinase by c-Abl-dependent and independent mechanisms
-
Pandey P, Raingeaud J, Kaneki M, Weichselbaum R, Davis RJ, Kufe D, Kharbanda S. Activation of p38 mitogen-activated protein kinase by c-Abl-dependent and independent mechanisms. J Biol Chem 271: 23775-23779, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 23775-23779
-
-
Pandey, P.1
Raingeaud, J.2
Kaneki, M.3
Weichselbaum, R.4
Davis, R.J.5
Kufe, D.6
Kharbanda, S.7
-
26
-
-
0034663060
-
The cJun N-terminal kinase (JNK) signaling pathway mediates induction of urokinase-type plasminogen activator (uPA) by the alkylating agent MNNG
-
Parra M, Lluis F, Miralles F, Caelles C, Munoz-Canoves P. The cJun N-terminal kinase (JNK) signaling pathway mediates induction of urokinase-type plasminogen activator (uPA) by the alkylating agent MNNG. Blood 96: 1415-1424, 2000
-
(2000)
Blood
, vol.96
, pp. 1415-1424
-
-
Parra, M.1
Lluis, F.2
Miralles, F.3
Caelles, C.4
Munoz-Canoves, P.5
-
27
-
-
0030051528
-
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
-
Raingeaud J, Whitmarsh AJ, Barrett T, Derijard B, Davis RJ. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol Cell Biol 16: 1247-1255, 1996
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1247-1255
-
-
Raingeaud, J.1
Whitmarsh, A.J.2
Barrett, T.3
Derijard, B.4
Davis, R.J.5
-
28
-
-
0029860936
-
Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors
-
Rosette C, Karin M. Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science 274: 1194-1197, 1996
-
(1996)
Science
, vol.274
, pp. 1194-1197
-
-
Rosette, C.1
Karin, M.2
-
29
-
-
0032548030
-
Ultraviolet-irradiation-induced apoptosis is mediated via ligand independent activation of tumor necrosis factor receptor 1
-
Sheikh MS, Antinore MJ, Huang Y, Fornace AJ. Ultraviolet-irradiation-induced apoptosis is mediated via ligand independent activation of tumor necrosis factor receptor 1. Oncogene 17: 2555-2563, 1998
-
(1998)
Oncogene
, vol.17
, pp. 2555-2563
-
-
Sheikh, M.S.1
Antinore, M.J.2
Huang, Y.3
Fornace, A.J.4
-
30
-
-
0030447483
-
The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex
-
Shu HB, Takeuchi M, Goeddel DV. The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex. Proc Natl Acad Sci 93: 13973-13978, 1996
-
(1996)
Proc Natl Acad Sci
, vol.93
, pp. 13973-13978
-
-
Shu, H.B.1
Takeuchi, M.2
Goeddel, D.V.3
-
31
-
-
0036882166
-
The absence of NF-kappaB-mediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis
-
Tang F, Tang G, Xiang J, Dai Q, Rosner MR, Lin A. The absence of NF-kappaB-mediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis. Mol Cell Biol 22: 8571-8579, 2002
-
(2002)
Mol Cell Biol
, vol.22
, pp. 8571-8579
-
-
Tang, F.1
Tang, G.2
Xiang, J.3
Dai, Q.4
Rosner, M.R.5
Lin, A.6
-
32
-
-
0031906667
-
UVB-induced association of tumor necrosis factor (TNF) receptor 1/TNF receptor-associated factor-2 mediates activation of Rel proteins
-
Tobin D, van Hogerlinden M, Toftgard R. UVB-induced association of tumor necrosis factor (TNF) receptor 1/TNF receptor-associated factor-2 mediates activation of Rel proteins. Proc Natl Acad Sci 95: 565-569, 1998
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 565-569
-
-
Tobin, D.1
van Hogerlinden, M.2
Toftgard, R.3
-
33
-
-
0034992168
-
MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines
-
Tournier C, Dong C, Turner TK, Jones SN, Flavell RA, Davis RJ. MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines. Genes Dev 15: 141914-141926, 2001
-
(2001)
Genes Dev
, vol.15
, pp. 141914-141926
-
-
Tournier, C.1
Dong, C.2
Turner, T.K.3
Jones, S.N.4
Flavell, R.A.5
Davis, R.J.6
-
34
-
-
0034693878
-
Regulation of cell death by the Abl tyrosine kinase
-
Wang JY. Regulation of cell death by the Abl tyrosine kinase. Oncogene 19: 5643-5650, 2000
-
(2000)
Oncogene
, vol.19
, pp. 5643-5650
-
-
Wang, J.Y.1
-
35
-
-
2242473920
-
Activation of SAPK/JNK signaling by protein kinase Cdelta in response to DNA damage
-
Yoshida K, Miki Y, Kufe D. Activation of SAPK/JNK signaling by protein kinase Cdelta in response to DNA damage. J Biol Chem 277: 48372-48378, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 48372-48378
-
-
Yoshida, K.1
Miki, Y.2
Kufe, D.3
-
36
-
-
0036479241
-
Requirement of ATM in UVA-induced signaling and apoptosis
-
Zhang Y, Ma WY, Kaji A, Bode AM, Dong Z. Requirement of ATM in UVA-induced signaling and apoptosis. J Biol Chem 277: 3124-3131, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 3124-3131
-
-
Zhang, Y.1
Ma, W.Y.2
Kaji, A.3
Bode, A.M.4
Dong, Z.5
-
37
-
-
34247383146
-
c-Jun N-terminal kinase mediates hydrogen peroxide-induced cell death via sustained poly (ADP-ribose) polymerase-1 activation
-
Zhang S, Lin Y, Kim YS, Hande MP, Liu ZG, Shen HM. c-Jun N-terminal kinase mediates hydrogen peroxide-induced cell death via sustained poly (ADP-ribose) polymerase-1 activation. Cell Death Differ 14: 1001-1010, 2007
-
(2007)
Cell Death Differ
, vol.14
, pp. 1001-1010
-
-
Zhang, S.1
Lin, Y.2
Kim, Y.S.3
Hande, M.P.4
Liu, Z.G.5
Shen, H.M.6
|