E-cadherin gene alterations in gastric cancers in different ethnic populations

Ethnicity and Disease

Volumn 18, Issue 2 SUPPL. 2, 2008, Pages

  Steinberg, Mark L ^a   Hwang, Bor Jang ^a   Tang, Laura ^c   Shah, Manish A ^b  

^a CITY COLLEGE OF NEW YORK   (United States)

^b Department of Medicine ^*  (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

E Cadherin alterations; Ethnic biomarkers; Gastric tumors

Indexed keywords

BETA CATENIN; BIOLOGICAL MARKER; DNA; PALINDROMIC DNA; PARAFFIN; UVOMORULIN; CADHERIN; TUMOR MARKER;

AFRICAN AMERICAN; ARTICLE; ASIAN; CANCER CENTER; CAUCASIAN; CONTROLLED STUDY; ETHNIC DIFFERENCE; ETHNICITY; EXON; GENE AMPLIFICATION; GENE DUPLICATION; GENE EXPRESSION; GENE FREQUENCY; GENE INSERTION; GENE INSERTION SEQUENCE; GENE MUTATION; GENE SEQUENCE; HISPANIC; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN LOCALIZATION; RACE DIFFERENCE; RETROSPECTIVE STUDY; SEQUENCE ANALYSIS; STOMACH CANCER; TISSUE SECTION; ASIAN AMERICAN; DNA SEQUENCE; ENZYME IMMUNOASSAY; ETHNOLOGY; FEMALE; GENETICS; MALE; MUTATION; POLYMERASE CHAIN REACTION; STOMACH TUMOR;

AFRICAN AMERICANS; ASIAN AMERICANS; CADHERINS; EUROPEAN CONTINENTAL ANCESTRY GROUP; EXONS; FEMALE; HISPANIC AMERICANS; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MUTATION; POLYMERASE CHAIN REACTION; RETROSPECTIVE STUDIES; SEQUENCE ANALYSIS, DNA; STOMACH NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 52149096961     PISSN: 1049510X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Parkin DM, Bray FI, Devesa SS. Cancer burden in the year 2000. The global picture. Eur J Cancer. 2001;37(8):4-66.
2. Ries LAG, Eisner MP, Kosary CL, et al. SEER Cancer Statistics Review, 1975-2001. Bethesda, Md: National Cancer Institute. Available at: http://seer.cancer.gov/csr/1975-2001/.
3. Keller G, Vogelsang H, Becker I, et al. Diffuse type gastric and lobular breast carcinoma in a familial gastric cancet patient with an E- cadherin germline mutation. Am J Pathol. 1999;155(2):337-342.
4. Suriano G, Mulholland D, de Wever O, et al. The intracellulat E-cadherin germline mutation V832 M lacks the ability to mediate cell- cell adhesion and to suppress invasion. Oncogene. 2003;22(36):5716-5719.
5. Suriano G, Yew S, Ferreira P, er al. Charac-rerizarion of a recurrenr germ line murarion of the E-cadherin gene: implications for generic resting and clinical managemenr. Clin Cancer Res. 2005; 11(15):5401-5409.
6. Lynch HT, Grady W, Suriano G, et al. Gastric cancer: new genetic developments. J Surg Oncol. 2005:90(3):114-133.
7. Kim HS, Hong EK, Park SY, et al. Expression of beta-carenin and E-cadherin in rhe adenoma-carcinoma sequence of the stomach. Anticancer Res. 2003;23(3c):2863-2868.
8. Cheng XX, Wang ZC, Chen XY, et al. Frequent loss of membranous E-cadherin in gastric cancers: a cross-ralk with Wnt in determining the fate of beta-catenin. Clin Exp Metastasis. 2005;22(l):85-93.
9. Berx G, Becker K-F, Höfler H, van Roy F. Mutations of the human E-cadherin (CDH1) gene. Hum Mut. 1998;12:226-237.
10. 13C resonance assignments and monomeric structure of the amino-terminal extracellular domain of epithelial cadherin. J BiomolNMR. 1996;7:173-189.
11. Koppert LB, van der Velden AW, van de Werering M, et al. Frequent loss of the AXIN1 locus but absence of AXIN1 gene mutations in adenocarcinomas of the gastro-oesophageal junction with nuclear b-catenin expression. Br J Cancer. 2004;90:892-899.
12. Ebert MP, Yu J, Hoffmann J, et al. Loss of beta-catenin expression in metastatic gastric cancer. J Clin Oncol. 2003:21 (9):1708-1714.
13. Clemenrs WM, Wang J, Sarnaik A, er al. β- Carenin mutation is a frequent cause of Wnt pathway activation in gastric cancer. Cancer Res. 2002;62(12);3503-3506.
14. Lin Y-M, Karo T, Saroh S, Yusuke N, Furukawa Y. Identification of novel polymorphisms in the AXIN1 and CDX-s genes. J Hum Genet. 2000;45:254-256.