Potassium deficiency results in accumulation of ultra-high molecular weight poly-β-hydroxybutyrate in a methane-utilizing mixed culture

Journal of Applied Microbiology

Volumn 105, Issue 4, 2008, Pages 1054-1061

  Helm, J ^a,b   Wendlandt, K D ^b   Jechorek, M ^b   Stottmeister, U ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

Author keywords

Methanotrophic bacteria; Methylocystis sp. GB25; Poly hydroxybutyrate; Potassium deficiency; Ultra high molecular weight PHB

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; IRON; MOLECULAR WEIGHT; POTASSIUM; SUBSTRATES; SULFUR;

GB25; METHANOTROPHIC BACTERIA; METHYLOCYSTI SP.; MIXED CULTURES; NUTRIENT DEFICIENCY; POLY-Β-HYDROXYBUTYRATE; POTASSIUM DEFICIENCY; ULTRA-HIGH MOLECULAR WEIGHT POLY-Β-HYDROXYBUTYRATE; ULTRA-HIGH-MOLECULAR-WEIGHT;

METHANE;

IRON; METHANE; POLY(3 HYDROXYBUTYRIC ACID); POTASSIUM; SULFUR;

ACCUMULATION; BIOMASS; EXPERIMENTAL STUDY; METHANE; METHANOGENIC BACTERIUM; POTASSIUM;

ARTICLE; BIOREACTOR; BIOSYNTHESIS; CONTROLLED STUDY; IRON DEFICIENCY; METHYLOCYSTACEAE; MOLECULAR WEIGHT; NONHUMAN; POLYMER PRODUCTION; POTASSIUM DEFICIENCY;

BACTERIA (MICROORGANISMS); METHYLOCYSTIS;

EID: 52049104449     PISSN: 13645072     EISSN: 13652672     Source Type: Journal    
DOI: 10.1111/j.1365-2672.2008.03831.x     Document Type: Article

References (62)

1. Anderson, A.J. Dawes, E.A. (1990) Occurrence, metabolism, metabolic role, and industrial uses of bacterial polyhydroxyalkanoates. Microbiol Rev 54, 450 472.
2. Aoyagi, Y., Doi, Y. Iwata, T. (2003) Mechanical properties and highly ordered structure of ultra-high-molecular-weight poly (R)-3-hydroxybutyrate films: effects of annealing and two-step drawing. Polym Degrad Stab 79, 209 216.
3. Asenjo, J.A. Suk, J.S. (1986) Microbial conversion of methane into poly-beta-hydroxybutyrate (PHB) - growth and intracellular product accumulation in a type-II methanotroph. J Ferment Technol 64, 271 278.
4. Asenjo, J.A., Schmidt, A.S., Andersen, P.R. Andrews, B.A. (1995) Effect of single nutrient limitation on poly-beta-hydroxybutyrate molecular weight distribution in Alcaligenes eutrophus. Biotechnol Bioeng 46, 497 502.
5. Babel, W., Ackermann, J.U. Breuer, U. (2001) Physiology, regulation, and limits of the synthesis of poly(3HB). Adv Biochem Eng Biotechnol 71, 125 157.
6. Basu, P., Katterle, B., Andersson, K.K. Dalton, H. (2003) The membrane-associated form of methane mono-oxygenase from Methylococcus capsulatus (Bath) is a copper/iron protein. Biochem J 369, 417 427.
7. Bourque, D., Pomerleau, Y. Groleau, D. (1995) High cell density production of poly-beta-hydroxybutyrate (PHB) from methanol by Methylobacterium extorquens: production of high-molecular-mass PHB. Appl Microbiol Biotechnol 44, 367 376.
8. Breuer, U. Babel, W. (1999) Methylobacterium rhodesianum produces poly-3-hydroxybutyrate and after mutagenesis in addition exopolysaccharides. Acta Biotechnol 19, 79 86.
9. Chen, G.Q. Page, W.J. (1994) The effect of substrate on the molecular weight of poly-beta-hydroxybutyrate produced by Azotobacter vinelandii UWD. Biotechnol Lett 16, 155 160.
10. Choi, J.I. Lee, S.Y. (2004) High level production of supra molecular weight poly(3-hydroxybutyrate) by metabolically engineered Escherichia coli. Biotechnol Bioprocess Eng 9, 196 200.
11. Cook, S.A. Shiemke, A.K. (1996) Evidence that copper is a required cofactor for the membrane-bound form of methane monooxygenase. J Inorg Biochem 63, 273 284.
12. Daniel, M., Choi, J.H., Kim, J.H. Lebeault, J.M. (1992) Effect of nutrient deficiency on accumulation and relative molecular weight of poly-beta-hydroxybutyric acid by methylotrophic bacterium, Pseudomonas 135. Appl Microbiol Biotechnol 37, 702 706.
13. Dias, J.M.L., Lemos, P.C., Serafim, L.S., Oliveira, C., Eiroa, M., Albuquerque, M.G.E., Ramos, A.M., Oliveira, R. et al. (2006) Recent advances in polyhydroxyalkanoate production by mixed aerobic cultures: from the substrate to the final product. Macromol Biosci 6, 885 906.
14. Geventman, L.H. (1999) Solubility of selected gases in water. In CRC Handbook of Chemistry and Physics ed. Lide, D.R. pp. 8-86 8-90. Boca Raton, FL : CRC Press.
15. + levels on poly(beta-hydroxybutyrate) production and growth in a continuous culture of Alcaligenes eutrophus. Biotechnol Prog 12, 234 239.
16. Gurieff, N. Lant, P. (2007) Comparative life cycle assessment and financial analysis of mixed culture polyhydroxyalkanoate production. Bioresour Technol 98, 3393 3403.
17. Hanson, R.S. Hanson, T.E. (1996) Methanotrophic bacteria. Microbiol Rev 60, 439 471.
18. Hazer, B. Steinbuchel, A. (2007) Increased diversification of polyhydroxyalkanoates by modification reactions for industrial and medical applications. Appl Microbiol Biotechnol 74, 1 12.
19. Helm, J., Wendlandt, K.-D., Rogge, G. Kappelmeyer, U. (2006) Characterizing a stable methane-utilising mixed culture used in the synthesis of a high quality biopolymer in an open system. J Appl Microbiol 101, 387 395.
20. Henderson, R.A. Jones, C.W. (1997) Physiology of poly-3-hydroxybutyrate (PHB) production by Alcaligenes eutrophus growing in continuous culture. Microbiology 143, 2361 2371.
21. Hori, K., Soga, K. Doi, Y. (1994) Effects of culture conditions on molecular weights of poly(3-hydroxyalkanoates) produced by Pseudomonas putida from octanoate. Biotechnol Lett 16, 709 714.
22. Kadouri, D., Jurkevitch, E., Okon, Y. Castro-Sowinski, S. (2005) Ecological and agricultural significance of bacterial polyhydroxyalkanoates. Crit Rev Microbiol 31, 55 67.
23. Kahar, P., Agus, J., Kikkawa, Y., Taguchi, K., Doi, Y. Tsuge, T. (2005) Effective production and kinetic characterization of ultra-high-molecular-weight poly (R)-3-hydroxybutyrate in recombinant Escherichia coli. Polym Degrad Stab 87, 161 169.
24. Kim, Y.B. Lenz, R.W. (2001) Polyesters from microorganisms. Adv Biochem Eng Biotechnol 71, 51 79.
25. Kim, S.W., Kim, P., Lee, H.S. Kim, J.H. (1996) High production of poly-beta-hydroxybutyrate (PHB) from Methylobacterium organophilum under potassium limitation. Biotechnol Lett 18, 25 30.
26. Kim, G.J., Lee, I.Y., Yoon, S.C., Shin, Y.C. Park, Y.H. (1997) Enhanced yield and a high production of medium-chain-length poly(3-hydroxyalkanoates) in a two-step fed-batch cultivation of Pseudomonas putida by combined use of glucose and octanoate. Enzyme Microb Technol 20, 500 505.
27. Kim, S.W., Kim, P. Kim, J.H. (1999a) Maximization of poly-beta- hydroxybutyrate accumulation by potassium limitation in Methylobacterium organophilum and its related metabolic analysis. J Microbiol Biotechnol 9, 140 146.
28. Kim, S.W., Kim, P. Kim, J.H. (1999b) Production of poly(3- hydroxybutyrate-co-3-hydroxyvalerate) from Methylobacterium organophilum by potassium-limited fed-batch culture. Enzyme Microb Technol 24, 555 560.
29. Kornberg, A., Rao, N.N. Ault-Riche, D. (1999) Inorganic polyphosphate: a molecule of many functions. Annu Rev Biochem 68, 89 125.
30. Kusaka, S., Abe, H., Lee, S.Y. Doi, Y. (1997) Molecular mass of poly (R)-3-hydroxybutyric acid produced in a recombinant Escherichia coli. Appl Microbiol Biotechnol 47, 140 143.
31. Kusaka, S., Iwata, T. Doi, Y. (1998) Microbial synthesis and physical properties of ultra-high-molecular-weight poly (R)-3-hydroxybutyrate. J Macromol Sci-Pure Appl Chem 35, 319 335.
32. Kusaka, S., Iwata, T. Doi, Y. (1999) Properties and biodegradability of ultra-high-molecular-weight poly (R)-3-hydroxybutyrate produced by a recombinant Escherichia coli. Int J Biol Macromol 25, 87 94.
33. Lee, I.Y., Kim, M.K., Chang, H.N. Park, Y.H. (1995) Regulation of poly-beta-hydroxybutyrate biosynthesis by nicotinamide nucleotide in Alcaligenes eutrophus. FEMS Microbiol Lett 131, 35 39.
34. Listewnik, H.F., Wendlandt, K.D., Jechorek, M. Mirschel, G. (2007) Process design for the microbial synthesis of poly-beta-hydroxybutyrate (PHB) from natural gas. Eng Life Sci 7, 278 282.
35. Mothes, G. (1997) Synthese von Polyhydroxybuttersäure (PHB) und ihre Regulation in methylotrophen "Serinwegbakterien". Leipzig : Department of Biochemistry, University of Leipzig.
36. Mothes, G., Rivera, I.S. Babel, W. (1996) Competition between beta-ketothiolase and citrate synthase during poly(beta-hydroxybutyrate) synthesis in Methylobacterium rhodesianum. Arch Microbiol 166, 405 410.
37. Murakami, R., Sato, H., Dybal, J., Iwata, T. Ozaki, Y. (2007) Formation and stability of beta-structure in biodegradable ultra-high-molecular-weight poly(3-hydroxybutyrate) by infrared, Raman, and quantum chemical calculation studies. Polymer 48, 2672 2680.
38. Murrell, J.C., Gilbert, B. McDonald, I.R. (2000a) Molecular biology and regulation of methane monooxygenase. Arch Microbiol 173, 325 332.
39. Murrell, J.C., McDonald, I.R. Gilbert, B. (2000b) Regulation of expression of methane monooxygenases by copper ions. Trends Microbiol 8, 221 225.
40. Philip, S., Keshavarz, T. Roy, I. (2007) Polyhydroxyalkanoates: biodegradable polymers with a range of applications. J Chem Technol Biotechnol 82, 233 247.
41. w) from Azotobacter chroococcum 6B. World J Microbiol Biotechnol 17, 9 14.
42. Rehm, B.H.A. Steinbüchel, A. (1999) Biochemical and genetic analysis of PHA synthases and other proteins required for PHA synthesis. Int J Biol Macromol 25, 3 19.
43. Riis, V. Mai, W. (1988) Gas chromatographic determination of poly-beta-hydroxybutyric acid in microbial biomass after hydrochloric acid propanolysis. J Chromatogr 445, 285 289.
44. Steinbüchel, A. (1996) PHB and other polyhydroxyalkanoic acids. In Biotechnology ed. Rehm, H.-J., Reed, G. Roehr, M. pp. 404 464. Weinheim : VCH Weinheim.
45. Steinbüchel, A. Schlegel, H.G. (1989) Excretion of pyruvate by mutants of Alcaligenes eutrophus, which are impaired in the accumulation of poly(beta-hydroxybutyric acid) (PHB), under conditions permitting synthesis of PHB. Appl Microbiol Biotechnol 31, 168 175.
46. Sudesh, K., Abe, H. Doi, Y. (2000) Synthesis, structure and properties of polyhydroxyalkanoates: biological polyesters. Prog Polym Sci 25, 1503 1555.
47. Suriyamongkol, P., Weselake, R., Narine, S., Moloney, M. Shah, S. (2007) Biotechnological approaches for the production of polyhydroxyalkanoates in microorganisms and plants - a review. Biotechnol Adv 25, 148 175.
48. Suzuki, T., Yamane, T. Shimizu, S. (1986) Mass production of poly-beta-hydroxybutyric acid by fully-automatic fed-batch culture of methylotrophs. Appl Microbiol Biotechnol 23, 322 329.
49. Suzuki, T., Deguchi, H., Yamane, T., Shimizu, S. Gekko, K. (1988) Control of molecular weight of poly-beta-hydroxybutyric acid produced in fed-batch culture of Protomonas extorquens. Appl Microbiol Biotechnol 27, 487 491.
50. Taidi, B., Anderson, A.J., Dawes, E.A. Byrom, D. (1994) Effect of carbon source and concentration on the molecular mass of poly(3-hydroxybutyrate) produced by Methylobacterium extorquens and Alcaligenes eutrophus. Appl Microbiol Biotechnol 40, 786 790.
51. Takeguchi, M., Ohashi, M. Okura, I. (1999) Role of iron in particulate methane monooxygenase from Methylosinus trichosporium OB3b. Biometals 12, 123 129.
52. Tempest, D.W. Wouters, J.T.M. (1981) Properties and performance of microorganisms in chemostat culture. Enzyme Microb Technol 3, 283 290.
53. Verlinden, R.A.J., Hill, D.J., Kenward, M.A., Williams, C.D. Radecka, I. (2007) Bacterial synthesis of biodegradable polyhydroxyalkanoates. J Appl Microbiol 102, 1437 1449.
54. Wendlandt, K.-D., Jechorek, M., Stottmeister, U., Helm, J., Rogge, G. Knaak, E. (1996) Verfahren zur Herstellung von Poly-β- hydroxybuttersäure und Copolymeren. Germany : Patent no. DD PS 19619074.
55. Wendlandt, K.-D., Jechorek, M., Helm, J. Stottmeister, U. (2001) Producing poly-3-hydroxybutyrate with a high molecular mass from methane. J Biotechnol 86, 127 133.
56. Yamane, T. (1993) Yield of poly-D(-)-3-hydroxybutyrate from various carbon sources - a theoretical study. Biotechnol Bioeng 41, 165 170.
57. Yamane, T., Fukunaga, M. Lee, Y.W. (1996) Increased PHB productivity by high-cell-density fed-batch culture of Alcaligenes latus, a growth-associated PHB producer. Biotechnol Bioeng 50, 197 202.
58. Yeom, S.H. Yoo, Y.J. (1995) Effect of pH on the molecular weight of poly-3-hydroxybutyric acid produced by Alcaligenes sp. Biotechnol Lett 17, 389 394.
59. Yoon, J.S., Park, S.K., Kim, Y.B., Maeng, H.Y. Rhee, Y.H. (1996) Culture conditions affecting the molecular weight distribution of poly(3- hydroxybutyrate-co-3-hydroxyvalerate) synthesized by Alcaligenes sp SH-69. J Microbiol 34, 279 283.
60. Young, F.K., Kastner, J.R. May, S.W. (1994) Microbial production of poly-beta-hydroxybutyric acid from D-xylose and lactose by Pseudomonas cepacia. Appl Environ Microbiol 60, 4195 4198.
61. Yu, H., Yin, J., Li, H., Yang, S. Shen, Z. (2000) Construction and selection of the novel recombinant Escherichia coli strain for poly(beta-hydroxybutyrate) production. J Biosci Bioeng 89, 307 311.
62. Zahn, J.A. DiSpirito, A.A. (1996) Membrane-associated methane monooxygenase from Methylococcus capsulatus (Bath). J Bacteriol 178, 1018 1029.