Double-stranded RNA - Activated protein kinase mediates induction of interleukin-8 expression by deoxynivalenol, shiga toxin 1, and ricin in monocytes

Toxicological Sciences

Volumn 105, Issue 2, 2008, Pages 322-330

  Gray, Jennifer S ^a,b   Bae, Hee Kyong ^b,c   Li, James C B ^d   Lau, Allan S ^d   Pestka, James J ^a,b,c  

^a Michigan State University ^*  (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c Michigan State University   (United States)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Immunotoxicity; Kinase; Ribotoxic stress chemokine

Indexed keywords

2 AMINOPURINE; DOUBLE STRANDED RNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MESSENGER RNA; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; RICIN; VEROTOXIN 1; VOMITOXIN;

ARTICLE; CELL LINE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOTOXICITY; MONOCYTE; PLASMID; PROTEIN BINDING; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RIBOSOME; RNA ISOLATION; STRESS;

DOSE-RESPONSE RELATIONSHIP, DRUG; EIF-2 KINASE; HUMANS; INTERLEUKIN-8; MONOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; PROTEIN SYNTHESIS INHIBITORS; RICIN; RNA, MESSENGER; SHIGA TOXIN 1; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; TRANSFECTION; TRICHOTHECENES; U937 CELLS; UP-REGULATION;

EID: 52049095281     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn128     Document Type: Article

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