Color-coded imaging of splenocyte-pancreatic cancer cell interactions in the tumor microenvironment

Cell Cycle

Volumn 7, Issue 18, 2008, Pages 2916-2921

  McElroy, Michele ^a   Kaushal, Sharmeela ^a   Bouvet, Michael ^a   Hoffman, Robert M ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b ANTICANCER INC   (United States)

Author keywords

Cancer immunity; GFP; Pancreatic cancer; RFP; Tumor imaging; Tumor microenvironment

Indexed keywords

GREEN FLUORESCENT PROTEIN; RED FLUORESCENT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL INTERACTION; CYTOPLASM; EXPERIMENTAL MOUSE; HIGH RESOLUTION COMPUTER TOMOGRAPHY; IMAGING; IMMUNOCOMPETENCE; IMMUNOCOMPETENT CELL; IN VIVO STUDY; LYMPHOID TISSUE; MICROENVIRONMENT; MOUSE; NONHUMAN; PANCREAS CANCER; SPLEEN CELL;

ANIMALIA; MUS MUSCULUS;

EID: 51849124195     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.7.18.6682     Document Type: Article

References (34)

1. Ries L, Melbert D, Krapcho M, Stinchcomb D, Howlader N, Horner M, Mariotto A, Miller B, Feuer E, Altekruse S, Lewis D, Clegg L, Eisner M, Reichman M, Edwards B. SEER Cancer Statistics Review, 1975-2005, National Cancer Institute. SEER Surveillance Epidemiology and End Results. Bethesda, MD, 2008:based on November 2007 SEER data submission, posted to the SEER web site, 8.
2. Wray CJ, Ahmad SA, Matthews JB, Lowy AM. Surgery for pancreatic cancer: recent controversies and current practice. Gastroenterology 2005; 128:1626-41.
3. Kamisawa T, Isawa T, Koike M, Tsuruta K, Okamoto A. Hematogenous metastases of pancreatic ductal carcinoma. Pancreas 1995; 11:345-9.
4. Pawlik TM, Gleisner AL, Cameron JL, Winter JM, Assumpcao L, Lillemoe KD, Wolfgang C, Hruban RH, Schulick RD, Yeo CJ, Choti MA. Prognostic relevance of lymph node ratio following pancreaticoduodenectomy for pancreatic cancer. Surgery 2007; 141:610-8.
5. Apte MV, Park S, Phillips PA, Santucci N, Goldstein D, Kumar RK, Ramm GA, Buchler M, Friess H, McCarroll JA, Keogh G, Merrett N, Pirola R, Wilson JS. Desmoplastic reaction in pancreatic cancer: role of pancreatic stellate cells. Pancreas 2004; 29:179-87.
6. Bachem MG, Schunemann M, Ramadani M, Siech M, Beger H, Buck A, Zhou S, Schmid-Kotsas A, Adler G. Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells. Gastroenterology 2005; 128:907-21.
7. Vonlaufen A, Joshi S, Qu C, Phillips PA, Xu Z, Parker NR, Toi CS, Pirola RC, Wilson JS, Goldstein D, Apte MV. Pancreatic stellate cells: partners in crime with pancreatic cancer cells. Cancer Res 2008; 68:2085-93.
8. Hwang RF, Moore T, Arumugam T, Ramachandran V, Amos KD, Rivera A, Ji B, Evans DB, Logsdon CD. Cancer-associated stromal fibroblasts promote pancreatic tumor progression. Cancer Res 2008; 68:918-26.
9. Balkwill F, Coussens LM. Cancer: an inflammatory link. Nature 2004; 431:405-6.
10. DeNardo DG, Johansson M, Coussens LM. Immune cells as mediators of solid tumor metastasis. Cancer Metastasis Rev 2008; 27:11-8.
11. Karin M, Greten FR. NFkappaB: linking inflammation and immunity to cancer development and progression. Nature Rev Immunol 2005; 5:749-59.
12. Coussens LM, Werb Z. Inflammation and cancer. Nature 2002; 420:860-7.
13. Bergers G, Brekken R, McMahon G, Vu TH, Itoh T, Tamaki K, Tanzawa K, Thorpe P, Itohara S, Werb Z, Hanahan D. Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nature Cell Biol 2000; 2:737-44.
14. Coussens LM, Raymond WW, Bergers G, Laig-Webster M, Behrendtsen O, Werb Z, Caughey GH, Hanahan D. Inflammatory mast cells upregulate angiogenesis during squamous epithelial carcinogenesis. Genes Dev 1999; 13:1382-97.
15. Balkwill F, Charles KA, Mantovani A. Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell 2005; 7:211-7.
16. Condeelis J, Pollard JW. Macrophages: obligate partners for tumor cell migration, invasion and metastasis. Cell 2006; 124:263-6.
17. Acuff HB, Carter KJ, Fingleton B, Gorden DL, Matrisian LM. Matrix metalloproteinase-9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment. Cancer Res 2006; 66:259-66.
18. Hiratsuka S, Watanabe A, Aburatani H, Maru Y. Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis. Nature Cell Biol 2006; 8:1369-75.
19. Kaplan RN, Psaila B, Lyden D. Bone marrow cells in the 'pre-metastatic niche': within bone and beyond. Cancer Metastasis Rev 2006; 25:521-9.
20. Ottobrini L, Lucignani G, Clerici M, Rescigno M. Assessing cell trafficking by noninvasive imaging techniques: applications in experimental tumor immunology. Q J Nucl Med Mol Imaging 2005; 49:361-6.
21. Klopp AH, Spaeth EL, Dembinski JL, Woodward WA, Munshi A, Meyn RE, Cox JD, Andreeff M, Marini FC. Tumor irradiation increases the recruitment of circulating mesenchymal stem cells into the tumor microenvironment. Cancer Res 2007; 67:11687-95.
22. Swirski FK, Berger CR, Figueiredo JL, Mempel TR, von Andrian UH, Pittet MJ, Weissleder R. A near-infrared cell tracker reagent for multiscopic in vivo imaging and quantification of leukocyte immune responses. PLoS ONE 2007; 2:e1075.
23. Yang M, Jiang P, Hoffman RM. Whole-body subcellular multicolor imaging of tumor-host interaction and drug response in real time. Cancer Res 2007; 67:5195-200.
24. Pahernik S, Griebel J, Botzlar A, Gneiting T, Brandl M, Dellian M, Goetz AE. Quantitative imaging of tumour blood flow by contrast-enhanced magnetic resonance imaging. Br J Cancer 2001; 85:1655-63.
25. Lewis JD, Destito G, Zijlstra A, Gonzalez MJ, Quigley JP, Manchester M, Stuhlmann H. Viral nanoparticles as tools for intravital vascular imaging. Nature Med 2006; 12:354-60.
26. Hoffman RM, Yang M. Color-coded fluorescence imaging of tumor-host interactions. Nature Protoc 2006; 1:928-35.
27. Jiang P, Yamauchi K, Yang M, Tsuji K, Xu M, Maitra A, Bouvet M, Hoffman RM. Tumor cells genetically labeled with GFP in the nucleus and RFP in the cytoplasm for imaging cellular dynamics. Cell Cycle 2006; 5:1198-201.
28. Glinsky GV, Glinskii AB, Berezovskaya O, Smith BA, Jiang P, Li XM, Yang M, Hoffman RM. Dual-color-coded imaging of viable circulating prostate carcinoma cells reveals genetic exchange between tumor cells in vivo, contributing to highly metastatic phenotypes. Cell Cycle 2006; 5:191-7.
29. Berezovska OP, Glinskii AB, Yang Z, Li XM, Hoffman RM, Glinsky GV. Essential role for activation of the Polycomb Group (PcG) protein chromatin silencing pathway in metastatic prostate cancer. Cell Cycle 2006; 5:1886-901.
30. Yamauchi K, Yang M, Hayashi K, Jiang P, Yamamoto N, Tsuchiya H, Tomita K, Moossa AR, Bouvet M, Hoffman RM. Imaging of nucleolar dynamics during the cell cycle of cancer cells in live mice. Cell Cycle 2007; 6:2706-8.
31. Hoffman RM. The multiple uses of fluorescent proteins to visualize cancer in vivo. Nature Rev Cancer 2005; 5:796-806.
32. Hoffman RM and Yang M. Subcellular imaging in the live mouse. Nature Protoc 2006; 1:775-82.
33. Hoffman RM and Yang M. Whole-body imaging with fluorescent proteins. Nature Protoc 2006; 1:1429-38.
34. Vintersten K, Monetti C, Gertsenstein M, Zhang P, Laszlo L, Biechele S, Nagy A. Mouse in red: red fluorescent protein expression in mouse ES cells, embryos, and adult animals. Genesis 2004; 40:241-6.