Cholesterol reduction attenuates 5-HT1A receptor-mediated signaling in human primary neuronal cultures

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 378, Issue 4, 2008, Pages 441-446

  Sjögren, Benita ^a   Csöregh, Linda ^a   Svenningsson, Per ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

5 HT1A receptors; 8 OH DPAT; Cholesterol; Lipid raft; Serotonin

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; CHOLESTEROL; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; G PROTEIN COUPLED RECEPTOR; METHYL BETA CYCLODEXTRIN; MITOGEN ACTIVATED PROTEIN KINASE 1; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN; SEROTONIN 1A RECEPTOR; SEROTONIN 7 RECEPTOR;

ARTICLE; CELL ASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEPLETION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LIGAND BINDING; LIPID RAFT; NERVE CELL CULTURE; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RECEPTOR DENSITY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; BETA-CYCLODEXTRINS; CELLS, CULTURED; CHOLESTEROL; CREB-BINDING PROTEIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHER-A-GO-GO POTASSIUM CHANNELS; HUMANS; IMMUNOBLOTTING; INTRACELLULAR FLUID; NEURONS; PHOSPHORYLATION; PIPERAZINES; PYRIDINES; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SIGNAL TRANSDUCTION;

EID: 51749125256     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-008-0323-6     Document Type: Article

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