Agonist properties of pindolol at h5-HT1A receptors coupled to mitogen-activated protein kinase

European Journal of Pharmacology

Volumn 424, Issue 1, 2001, Pages 13-17

  Millan, Mark J ^a   Newman Tancredi, Adrian ^a   Duqueyroix, Delphine ^a   Cussac, Didier ^a  

^a INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

(+)8 OH DPAT ((+)8 Hydroxy dipropyl amino tetralin); ( ) Pindolol; G protein; H5 HT1A receptor; MAPK (Mitogen activated protein kinase)

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 2,3,6,7 TETRAHYDRO 1' METHYL 5 [[2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL) 4 BIPHENYLYL]CARBONYL]SPIRO[FURO[2,3 F]INDOLE 3,4' PIPERIDINE]; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PERTUSSIS TOXIN; PINDOLOL; SEROTONIN 1A RECEPTOR; SEROTONIN AGONIST;

ANIMAL CELL; ARTICLE; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; ENZYME ACTIVATION; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; CHO CELLS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; PINDOLOL; PIPERAZINES; PYRIDINES; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS;

EID: 0035854560     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)01127-X     Document Type: Article

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