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Volumn 128, Issue 10, 2008, Pages 2474-2484

Knockdown of myosin Va isoforms by RNAi as a tool to block melanosome transport in primary human melanocytes

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; LENTIVIRUS VECTOR; MELANOPHILIN; MYOSIN VA; PROTEIN SLAC2 A; RAB27A PROTEIN; UNCLASSIFIED DRUG;

EID: 51749094612     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2008.100     Document Type: Article
Times cited : (31)

References (55)
  • 2
    • 0038075377 scopus 로고    scopus 로고
    • Characterization of the molecular defects in Rab27a, caused by RAB27A missense mutations found in patients with Griscelli syndrome
    • Bahadoran P, Busca R, Chiaverini C, Westbroek W, Lambert J, Bille K et al. (2003) Characterization of the molecular defects in Rab27a, caused by RAB27A missense mutations found in patients with Griscelli syndrome. J Biol Chem 278:11386-92
    • (2003) J Biol Chem , vol.278 , pp. 11386-11392
    • Bahadoran, P.1    Busca, R.2    Chiaverini, C.3    Westbroek, W.4    Lambert, J.5    Bille, K.6
  • 3
    • 31544456413 scopus 로고    scopus 로고
    • Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging
    • Bartlett DW, Davis ME (2006) Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging. Nucleic Acids Res 34:322-33
    • (2006) Nucleic Acids Res , vol.34 , pp. 322-333
    • Bartlett, D.W.1    Davis, M.E.2
  • 4
    • 0038580778 scopus 로고    scopus 로고
    • Chemical and instrumental approaches to treat hyperpigmentation
    • Briganti S, Camera E, Picardo M (2003) Chemical and instrumental approaches to treat hyperpigmentation. Pigment Cell Res 16:101-10
    • (2003) Pigment Cell Res , vol.16 , pp. 101-110
    • Briganti, S.1    Camera, E.2    Picardo, M.3
  • 8
    • 1242329406 scopus 로고    scopus 로고
    • Missense mutations in the globular tail of myosin-Va in dilute mice partially impair binding of Slac2-a/melanophilin
    • Fukuda M, Kuroda TS (2004) Missense mutations in the globular tail of myosin-Va in dilute mice partially impair binding of Slac2-a/melanophilin. J Cell Sci 117:583-91
    • (2004) J Cell Sci , vol.117 , pp. 583-591
    • Fukuda, M.1    Kuroda, T.S.2
  • 9
    • 0037023745 scopus 로고    scopus 로고
    • Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: Implications of a tripartite protein complex for melanosome transport
    • Fukuda M, Kuroda TS, Mikoshiba K (2002) Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport. J Biol Chem 277:12432-6
    • (2002) J Biol Chem , vol.277 , pp. 12432-12436
    • Fukuda, M.1    Kuroda, T.S.2    Mikoshiba, K.3
  • 11
    • 4544278598 scopus 로고    scopus 로고
    • Topical agents used in the management of hyperpigmentation
    • Halder RM, Richards GM (2004) Topical agents used in the management of hyperpigmentation. Skin Therapy Lett 9:1-3
    • (2004) Skin Therapy Lett , vol.9 , pp. 1-3
    • Halder, R.M.1    Richards, G.M.2
  • 13
    • 0037089135 scopus 로고    scopus 로고
    • Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor
    • Holen T, Amarzguioui M, Wiiger MT, Babaie E, Prydz H (2002) Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor. Nucleic Acids Res 30:1757-66
    • (2002) Nucleic Acids Res , vol.30 , pp. 1757-1766
    • Holen, T.1    Amarzguioui, M.2    Wiiger, M.T.3    Babaie, E.4    Prydz, H.5
  • 15
    • 0036099629 scopus 로고    scopus 로고
    • The leaden gene product is required with Rab27a to recruit myosin Va to melanosomes in melanocytes
    • Hume AN, Collinson LM, Hopkins CR, Strom M, Barral DC, Bossi G et al. (2002) The leaden gene product is required with Rab27a to recruit myosin Va to melanosomes in melanocytes. Traffic 3:193-202
    • (2002) Traffic , vol.3 , pp. 193-202
    • Hume, A.N.1    Collinson, L.M.2    Hopkins, C.R.3    Strom, M.4    Barral, D.C.5    Bossi, G.6
  • 17
    • 33750520133 scopus 로고    scopus 로고
    • A coiled-coil domain of melanophilin is essential for myosin Va recruitment and melanosome transport in melanocytes
    • Hume AN, Tarafder AK, Ramalho JS, Sviderskaya EV, Seabra MC (2006) A coiled-coil domain of melanophilin is essential for myosin Va recruitment and melanosome transport in melanocytes. Mol Biol Cell 17:4720-35
    • (2006) Mol Biol Cell , vol.17 , pp. 4720-4735
    • Hume, A.N.1    Tarafder, A.K.2    Ramalho, J.S.3    Sviderskaya, E.V.4    Seabra, M.C.5
  • 18
    • 34948826453 scopus 로고    scopus 로고
    • Rab27a and MyoVa are the primary Mlph interactors regulating melanosome transport in melanocytes
    • Hume AN, Ushakov DS, Tarafder AK, Ferenczi MA, Seabra MC (2007) Rab27a and MyoVa are the primary Mlph interactors regulating melanosome transport in melanocytes. J Cell Sci 120:3111-22
    • (2007) J Cell Sci , vol.120 , pp. 3111-3122
    • Hume, A.N.1    Ushakov, D.S.2    Tarafder, A.K.3    Ferenczi, M.A.4    Seabra, M.C.5
  • 20
    • 0036534444 scopus 로고    scopus 로고
    • Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA
    • Kisielow M, Kleiner S, Nagasawa M, Faisal A, Nagamine Y (2002) Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA. Biochem J 363:1-5
    • (2002) Biochem J , vol.363 , pp. 1-5
    • Kisielow, M.1    Kleiner, S.2    Nagasawa, M.3    Faisal, A.4    Nagamine, Y.5
  • 22
    • 0034004926 scopus 로고    scopus 로고
    • arg-cys substitution at codon 1246 of the human myosin Va gene is not associated with Griscelli syndrome
    • Lambert J, Naeyaert JM, De Paepe A, Van Coster R, Ferster A, Song M et al. (2000) arg-cys substitution at codon 1246 of the human myosin Va gene is not associated with Griscelli syndrome. J Invest Dermatol 114:731-3
    • (2000) J Invest Dermatol , vol.114 , pp. 731-733
    • Lambert, J.1    Naeyaert, J.M.2    De Paepe, A.3    Van Coster, R.4    Ferster, A.5    Song, M.6
  • 23
    • 0031737659 scopus 로고    scopus 로고
    • Myosin V colocalizes with melanosomes and subcortical actin bundles not associated with stress fibers in human epidermal melanocytes
    • Lambert J, Onderwater J, Vander Haeghen Y, Vancoillie G, Koerten HK, Mommaas AM et al. (1998a) Myosin V colocalizes with melanosomes and subcortical actin bundles not associated with stress fibers in human epidermal melanocytes. J Invest Dermatol 111:835-40
    • (1998) J Invest Dermatol , vol.111 , pp. 835-840
    • Lambert, J.1    Onderwater, J.2    Vander Haeghen, Y.3    Vancoillie, G.4    Koerten, H.K.5    Mommaas, A.M.6
  • 25
    • 0036898465 scopus 로고    scopus 로고
    • Myosin-V, a versatile motor for short-range vesicle transport
    • Langford GM (2002) Myosin-V, a versatile motor for short-range vesicle transport. Traffic 3:859-65
    • (2002) Traffic , vol.3 , pp. 859-865
    • Langford, G.M.1
  • 26
    • 21344457432 scopus 로고    scopus 로고
    • RNA interference: From gene silencing to gene-specific therapeutics
    • Leung RK, Whittaker PA (2005) RNA interference: from gene silencing to gene-specific therapeutics. Pharmacol Ther 107:222-39
    • (2005) Pharmacol Ther , vol.107 , pp. 222-239
    • Leung, R.K.1    Whittaker, P.A.2
  • 27
    • 0031896101 scopus 로고    scopus 로고
    • Partial albinism with immunodeficiency: Griscelli syndrome: report of a case and review of the literature
    • Mancini AJ, Chan LS, Paller AS (1998) Partial albinism with immunodeficiency: Griscelli syndrome: report of a case and review of the literature. J Am Acad Dermatol 38:295-300
    • (1998) J Am Acad Dermatol , vol.38 , pp. 295-300
    • Mancini, A.J.1    Chan, L.S.2    Paller, A.S.3
  • 28
    • 0035490904 scopus 로고    scopus 로고
    • The melanosome: Membrane dynamics in black and white
    • Marks MS, Seabra MC (2001) The melanosome: membrane dynamics in black and white. Nat Rev Mol Cell Biol 2:738-48
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 738-748
    • Marks, M.S.1    Seabra, M.C.2
  • 29
    • 0035964395 scopus 로고    scopus 로고
    • Matesic LE, Yip R, Reuss AE, Swing DA, O'Sullivan TN, Fletcher CF et al. (2001) Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice. Proc Natl Acad Sci USA 98:10238-43
    • Matesic LE, Yip R, Reuss AE, Swing DA, O'Sullivan TN, Fletcher CF et al. (2001) Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice. Proc Natl Acad Sci USA 98:10238-43
  • 31
    • 0038107403 scopus 로고    scopus 로고
    • Biochemical and functional characterization of Rab27a mutations occurring in Griscelli syndrome patients
    • Menasche G, Feldmann J, Houdusse A, Desaymard C, Fischer A, Goud B et al. (2003a) Biochemical and functional characterization of Rab27a mutations occurring in Griscelli syndrome patients. Blood 101:2736-42
    • (2003) Blood , vol.101 , pp. 2736-2742
    • Menasche, G.1    Feldmann, J.2    Houdusse, A.3    Desaymard, C.4    Fischer, A.5    Goud, B.6
  • 32
    • 0042388106 scopus 로고    scopus 로고
    • Griscelli syndrome restricted to hypopigmentation results from a melanophilin defect (GS3) or a MYO5A F-exon deletion (GS1)
    • Menasche G, Ho CH, Sanal O, Feldmann J, Tezcan I, Ersoy F et al. (2003b) Griscelli syndrome restricted to hypopigmentation results from a melanophilin defect (GS3) or a MYO5A F-exon deletion (GS1). J Clin Invest 112:450-6
    • (2003) J Clin Invest , vol.112 , pp. 450-456
    • Menasche, G.1    Ho, C.H.2    Sanal, O.3    Feldmann, J.4    Tezcan, I.5    Ersoy, F.6
  • 33
    • 0344002689 scopus 로고    scopus 로고
    • Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome
    • Menasche G, Pastural E, Feldmann J, Certain S, Ersoy F, Dupuis S et al. (2000) Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome. Nat Genet 25:173-6
    • (2000) Nat Genet , vol.25 , pp. 173-176
    • Menasche, G.1    Pastural, E.2    Feldmann, J.3    Certain, S.4    Ersoy, F.5    Dupuis, S.6
  • 35
    • 0024059809 scopus 로고
    • The murine dilute suppressor gene dsu suppresses the coat-color phenotype of three pigment mutations that alter melanocyte morphology, d, ash and ln
    • Moore KJ, Swing DA, Rinchik EM, Mucenski ML, Buchberg AM, Copeland NG et al. (1988) The murine dilute suppressor gene dsu suppresses the coat-color phenotype of three pigment mutations that alter melanocyte morphology, d, ash and ln. Genetics 119:933-41
    • (1988) Genetics , vol.119 , pp. 933-941
    • Moore, K.J.1    Swing, D.A.2    Rinchik, E.M.3    Mucenski, M.L.4    Buchberg, A.M.5    Copeland, N.G.6
  • 36
    • 0026015177 scopus 로고
    • Pigment content of cultured human melanocytes does not correlate with tyrosinase message level
    • Naeyaert JM, Eller M, Gordon PR, Park HY, Gilchrest BA (1991) Pigment content of cultured human melanocytes does not correlate with tyrosinase message level. Br J Dermatol 125:297-303
    • (1991) Br J Dermatol , vol.125 , pp. 297-303
    • Naeyaert, J.M.1    Eller, M.2    Gordon, P.R.3    Park, H.Y.4    Gilchrest, B.A.5
  • 38
    • 10044225973 scopus 로고    scopus 로고
    • O'Sullivan TN, Wu XS, Rachel RA, Huang JD, Swing DA, Matesic LE et al. (2004) dsu functions in a MYO5A-independent pathway to suppress the coat color of dilute mice. Proc Natl Acad Sci USA 101:16831-6
    • O'Sullivan TN, Wu XS, Rachel RA, Huang JD, Swing DA, Matesic LE et al. (2004) dsu functions in a MYO5A-independent pathway to suppress the coat color of dilute mice. Proc Natl Acad Sci USA 101:16831-6
  • 39
    • 0030914460 scopus 로고    scopus 로고
    • Griscelli disease maps to chromosome 15q21 and is associated with mutations in the myosin-Va gene
    • Pastural E, Barrat FJ, Dufourcq-Lagelouse R, Certain S, Sanal O, Jabado N et al. (1997) Griscelli disease maps to chromosome 15q21 and is associated with mutations in the myosin-Va gene. Nat Genet 16:289-92
    • (1997) Nat Genet , vol.16 , pp. 289-292
    • Pastural, E.1    Barrat, F.J.2    Dufourcq-Lagelouse, R.3    Certain, S.4    Sanal, O.5    Jabado, N.6
  • 40
    • 0036107354 scopus 로고    scopus 로고
    • Melanophilin, the product of the leaden locus, is required for targeting of myosin-Va to melanosomes
    • Provance DW, James TL, Mercer JA (2002) Melanophilin, the product of the leaden locus, is required for targeting of myosin-Va to melanosomes. Traffic 3:124-32
    • (2002) Traffic , vol.3 , pp. 124-132
    • Provance, D.W.1    James, T.L.2    Mercer, J.A.3
  • 42
    • 0037067673 scopus 로고    scopus 로고
    • A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport
    • Strom M, Hume AN, Tarafder AK, Barkagianni E, Seabra MC (2002) A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport. J Biol Chem 277:25423-30
    • (2002) J Biol Chem , vol.277 , pp. 25423-25430
    • Strom, M.1    Hume, A.N.2    Tarafder, A.K.3    Barkagianni, E.4    Seabra, M.C.5
  • 43
  • 45
    • 0000972148 scopus 로고    scopus 로고
    • Kinesin and kinectin can associate with the melanosomal surface and form a link with microtubules in normal human melanocytes
    • Vancoillie G, Lambert J, Mulder A, Koerten HK, Mommaas AM, Van Oostveldt P et al. (2000b) Kinesin and kinectin can associate with the melanosomal surface and form a link with microtubules in normal human melanocytes. J Invest Dermatol 114:421-9
    • (2000) J Invest Dermatol , vol.114 , pp. 421-429
    • Vancoillie, G.1    Lambert, J.2    Mulder, A.3    Koerten, H.K.4    Mommaas, A.M.5    Van Oostveldt, P.6
  • 46
    • 0036534582 scopus 로고    scopus 로고
    • Elimination of primer-dimer artifacts and genomic coamplification using a two-step SYBR green I real-time RT-PCR
    • Vandesompele J, De Paepe A, Speleman F (2002a) Elimination of primer-dimer artifacts and genomic coamplification using a two-step SYBR green I real-time RT-PCR. Anal Biochem 303:95-8
    • (2002) Anal Biochem , vol.303 , pp. 95-98
    • Vandesompele, J.1    De Paepe, A.2    Speleman, F.3
  • 47
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A et al. (2002b) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3:RESEARCH0034
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6
  • 49
    • 0037336463 scopus 로고    scopus 로고
    • Interactions of human myosin Va isoforms, endogenously expressed in human melanocytes, are tightly regulated by the tail domain
    • Westbroek W, Lambert J, Bahadoran P, Busca R, Herteleer MC, Smit N et al. (2003) Interactions of human myosin Va isoforms, endogenously expressed in human melanocytes, are tightly regulated by the tail domain. J Invest Dermatol 120:465-75
    • (2003) J Invest Dermatol , vol.120 , pp. 465-475
    • Westbroek, W.1    Lambert, J.2    Bahadoran, P.3    Busca, R.4    Herteleer, M.C.5    Smit, N.6
  • 50
    • 4644342256 scopus 로고    scopus 로고
    • Rab27b is upregulated in human Griscelli syndrome type II melanocytes and linked to the actin cytoskeleton via exon F-myosin Va transcripts
    • Westbroek W, Lambert J, De Schepper S, Kleta R, Van Den Bossche K, Seabra MC et al. (2004) Rab27b is upregulated in human Griscelli syndrome type II melanocytes and linked to the actin cytoskeleton via exon F-myosin Va transcripts. Pigment Cell Res 17:498-505
    • (2004) Pigment Cell Res , vol.17 , pp. 498-505
    • Westbroek, W.1    Lambert, J.2    De Schepper, S.3    Kleta, R.4    Van Den Bossche, K.5    Seabra, M.C.6
  • 51
    • 12944255844 scopus 로고    scopus 로고
    • Wilson SM, Yip R, Swing DA, O'Sullivan TN, Zhang Y, Novak EK et al. (2000) A mutation in Rab27a causes the vesicle transport defects observed in ashen mice. Proc Natl Acad Sci USA 97:7933-8
    • Wilson SM, Yip R, Swing DA, O'Sullivan TN, Zhang Y, Novak EK et al. (2000) A mutation in Rab27a causes the vesicle transport defects observed in ashen mice. Proc Natl Acad Sci USA 97:7933-8
  • 52
    • 0035073174 scopus 로고    scopus 로고
    • Rab27a enables myosin Va-dependent melanosome capture by recruiting the myosin to the organelle
    • Wu X, Rao K, Bowers MB, Copeland NG, Jenkins NA, Hammer JA III (2001) Rab27a enables myosin Va-dependent melanosome capture by recruiting the myosin to the organelle. J Cell Sci 114:1091-100
    • (2001) J Cell Sci , vol.114 , pp. 1091-1100
    • Wu, X.1    Rao, K.2    Bowers, M.B.3    Copeland, N.G.4    Jenkins, N.A.5    Hammer III, J.A.6
  • 53
    • 0036000020 scopus 로고    scopus 로고
    • Rab27a is an essential component of melanosome receptor for myosin Va
    • Wu X, Wang F, Rao K, Sellers JR, Hammer JA III (2002a) Rab27a is an essential component of melanosome receptor for myosin Va. Mol Biol Cell 13:1735-49
    • (2002) Mol Biol Cell , vol.13 , pp. 1735-1749
    • Wu, X.1    Wang, F.2    Rao, K.3    Sellers, J.R.4    Hammer III, J.A.5
  • 55
    • 27544458296 scopus 로고    scopus 로고
    • Melanophilin and myosin Va track the microtubule plus end on EB1
    • Wu XS, Tsan GL, Hammer JA III (2005) Melanophilin and myosin Va track the microtubule plus end on EB1. J Cell Biol 171:201-7
    • (2005) J Cell Biol , vol.171 , pp. 201-207
    • Wu, X.S.1    Tsan, G.L.2    Hammer III, J.A.3


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