The Effect of Halofuginone, a Specific Inhibitor of Collagen Type 1 Synthesis, in the Prevention of Pancreatic Fibrosis in an Experimental Model of Severe Hyperstimulation and Obstruction Pancreatitis

Journal of Surgical Research

Volumn 148, Issue 1, 2008, Pages 7-12

  Karatas, Adem ^a   Paksoy, Melih ^a   Erzin, Yusuf ^a   Carkman, Sinan ^a   Gonenc, Murat ^a   Ayan, Fadil ^a   Aydogan, Fatih ^a   Uzun, Hafize ^a   Durak, Haydar ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

Author keywords

chronic pancreatitis; halofuginone; pancreatic fibrosis; SHOP model

Indexed keywords

AMYLASE; CERULETIDE; COLLAGEN TYPE 1; GLUTATHIONE; HALOFUGINONE; HYALURONIC ACID; HYDROXYPROLINE; MALONALDEHYDE; NITRIC OXIDE; TRIACYLGLYCEROL LIPASE;

ACINAR CELL; AMYLASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATROPHY; BLOOD LEVEL; CHEMICAL ANALYSIS; CHRONIC PANCREATITIS; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CYSTIC FIBROSIS; DISEASE SEVERITY; DRUG EFFICACY; ENZYME ACTIVITY; ERYTHROCYTE LEVEL; FEMALE; FIBROGENESIS; HISTOPATHOLOGY; LAPAROTOMY; LIPID PEROXIDATION; MORTALITY; NONHUMAN; PANCREAS DUCT STENOSIS; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RAT; STIMULATION; TISSUE LEVEL; TRIACYLGLYCEROL LIPASE BLOOD LEVEL;

AMYLASES; ANIMALS; COLLAGEN TYPE I; DISEASE MODELS, ANIMAL; FEMALE; FIBROSIS; HYALURONIC ACID; LIPASE; NITRIC OXIDE; PANCREAS; PANCREATIC DISEASES; PANCREATITIS; PIPERIDINES; PROTEIN SYNTHESIS INHIBITORS; QUINAZOLINONES; RATS; RATS, WISTAR;

EID: 51749090436     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2008.03.015     Document Type: Article

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