Monolithic integration of poly(dimethylsiloxane) waveguides and microfluidics for on-chip absorbance measurements

Sensors and Actuators, B: Chemical

Volumn 134, Issue 2, 2008, Pages 532-538

  Kee, Jack Sheng ^a,b   Poenar, Daniel Puiu ^b   Neuzil, Pavel ^a   Yobas, Levent ^a  

^a INSTITUTE OF MICROELECTRONICS   (Singapore)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Absorbance; Micro total analysis systems; Poly(dimethylsiloxane); Polymer Waveguides

Indexed keywords

CLADDING (COATING); COMPUTER NETWORKS; INTEGRATED OPTICS; MICROCHANNELS; OPTICAL PROPERTIES; REFRACTIVE INDEX; SILICONES;

ABSORBANCE; MICRO-TOTAL-ANALYSIS SYSTEMS; MONOLITHIC INTEGRATIONS; POLY(DIMETHYLSILOXANE); POLYMER WAVEGUIDES;

MONOLITHIC INTEGRATED CIRCUITS;

EID: 51649114212     PISSN: 09254005     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.snb.2008.05.040     Document Type: Article

References (33)

1. Mogensen K.B., Klank H., and Kutter J.P. Recent developments in detection for microfluidic systems. Electrophoresis 25 (2004) 3498-3512
2. Swiney K., and Bornhop D.J. Detection in capillary electrophoresis. Electrophoresis 21 (2000) 1239-1250
3. Verpoorte E. Chip vision-optics for microchips. Lab Chip 3 (2003) N42-N52 240
4. Liang Z.H., Chiem N., Ocvirk G., Tang T., Fluri K., and Harrison D.J. Microfabrication of a planar absorbance and fluorescence cell for integrated capillary electrophoresis devices. Anal. Chem. 68 (1996) 1040-1046
5. Roulet J.C., Volkel R., Herzig H.P., Verpoorte E., De Rooij N.F., and Dandliker R. Performance of an integrated microoptical system for fluorescence detection in microfluidic systems. Anal. Chem. 74 (2002) 3400-3407
6. Llobera A., Wilke R., and Buttgenbach S. Poly(dimethylsiloxane) hollow Abbe prism with microlenses for detection based on absorption and refractive index shift. Lab Chip 4 (2004) 24-27
7. Wang Z., El-Ali J., Engelund M., Gotsaed T., Perch-Nielsen I.R., Mogensen K.B., Snakenborg D., Kutter J.P., and Wolff A. Measurement of scattered light on a microchip flow cytometer with integrated polymer based optical elements. Lab Chip 4 (2004) 372-377
8. Mogensen K.B., Petersen N.J., Hubner J., and Kutter J.P. Monolithic integration of optical waveguides for absorbance detection in microfabricated electrophoresis devices. Electrophoresis 22 (2001) 3930-3938
9. Mogensen K.B., Kwok Y.C., Ejikel Jan.C.T., Petersen N.J., Manz A., and Kutter J.P. A microfluidic device with an integrated waveguide beam splitter for velocity measurements of flowing particles by Fourier transformation. Anal. Chem. 75 (2003) 4931-4936
10. Veldhuis G.J., and Lambeck P.V. Highly-sensitive passive integrated optical spiral-shaped waveguide refractometer. Appl. Phys. Lett. 71 1 (1997) 2895-2897
11. Petersen N.J., Mogensen K.B., and Kutter J.P. Performance of an in-plane detection cell with integrated waveguides for UV/Vis absorbance measurements on microfluidic separation devices. Electrophoresis 23 (2002) 3528-3536
12. Mogensen K.B., El-Ali J., Wolff A., and Kutter J.P. Integration of polymer waveguides for optical detection in microfabricated chemical analysis systems. Appl. Opt. 42 (2003) 4072-4079
13. Chang-Yen D.A., and Gale B.K. An integrated optical oxygen sensor fabricated using rapid-prototyping techniques. Lab Chip 3 (2003) 297-301
14. Ruano-Lopez J.M., Aguirregabiria M., Tijero M., Arroyo M.T., Elizalde J., Berganzo J., Aranburu I., Blanco F.J., and Mayora K. A new SU-8 process to integrate buried waveguides and sealed microchannels for a lab-on-a-chip. Sens. Actuators B 114 (2006) 542-551
15. Snakenborg D., Perozziello G., Klank H., Geschke O., and Kutter J.P. Direct milling and casting of polymer-based optical waveguides for improved transparency in the visible range. J. Micromech. Microeng. 16 (2006) 375-381
16. Sia S.K., and Whitesides G.M. Microfluidic devices fabricated in poly(dimethylsiloxane) for biological studies. Electrophoresis 24 (2003) 3563-3576
17. Kopetz S., Cai D., Rabe E., and Neyer A. PDMS-based optical waveguide layer for integration in electrical-optical circuit boards. Int. J. Electron. Commun. (AEU) 61 (2007) 163-167
18. Kou Q., Yesilyurt I., Studer V., Belotti M., Cambril E., and Chen Y. On-chip optical components and microfluidic systems. Microelectron. Eng. 73 (2004) 876-880
19. Camou S., Fujita H., and Fujii T. PDMS 2D optical lens integrated with microfluidic channels: principle and characterization. Lab Chip 3 (2003) 40-45
20. Hofmann O., Wang X., Cornwell A., Beecher S., Raja A., Bradley D.D.C., deMello A.J., and deMello J.C. Monolithically integrated dye-doped PDMS long-pass filters for disposable on-chip fluorescence detection. Lab Chip 6 (2006) 981-987
21. Chang-Yen D.A., Eich R.K., and Gale B.K. A monolithic PDMS waveguide system fabricated using soft-lithography techniques. J. Lightwave Technol. 6 (2005) 2088-2093
22. Splawn B.G., and Lytle F.E. On-chip absorption measurements using an integrated waveguide. Anal. Bioanal. Chem. 373 (2002) 519-525
23. Wolfe D.B., Conroy R.S., Garstecki P., Mayers B.T., Fischbach M.A., Paul K.E., Prentiss M., and Whitesides G.M. Dynamic control of liquid-core/liquid-cladding optical waveguides. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 12434-12438
24. Novak L., Neuzil P., Pipper J., Zhang Y., and Lee S. An integrated fluorescence detection system for lab-on-a-chip. Lab Chip 7 (2007) 27-29
25. Diemeer M., Hilderink L., Dekker R., and Driessen A. Low-cost and low-loss multimode waveguides of photodefi{ligature}nable epoxy. IEEE Photon. Tech. Electr. Lett. 18 (2006) 1624-1626
26. Chuang W.C., Ho C.T., and Chang W.C. Fabrication of polymer waveguides by a replication method. Appl. Opt. 45 (2006) 8304-8307
27. Howley B., Wang X., Chen R.T., and Chen Y. Experimental evaluation of curved polymer waveguides with air trenches and offsets. J. Appl. Phys. 100 (2006) 023114
28. Mogensen K.B., Eriksson F., Gustafsson O., Nikolajsen R.P.H., and Kutter J.P. Pure-silica optical waveguides, fiber couplers, and high-aspect ratio submicrometer channels for electrokinetic separation devices. Electrophoresis 25 (2004) 3788-3795
29. Losada M.A., Garces I., Mateo J., Salinas I., Lou J., and Zubia J. Mode coupling contribution to radiation losses in curvatures for high and low numerical aperture plastic optical fibers. J. Lightwave Technol. 20 (2002) 1160-1164
30. Papakonstantinou I., Wang K., Selviah D.R., and Fernandez F.A. Transition, radiation and propagation loss in polymer multimode waveguide bends. Opt. Express 15 (2007) 669-679
31. Subramaniam V., De Brabander G.N., Naghski D.H., and Boyd J.T. Measurement of mode field profiles and bending and transition losses in curved optical channel waveguides. J. Lightwave Technol. 15 (1997) 990-997
32. Salinas I., Garces I., Alonso R., Llobera A., and Domiguez C. Simple estimation of transition losses in bends of wide optical waveguides by a ray tracing method. IEEE Photon. Tech. Lett. 16 (2004) 825-827
33. Snakenborg D., Mogensen K.B., and kutter P.J. Optimization of signal-to-noise ratio in absorbance detection by integration of microoptical components. μTAS (2003) 841-844