Spastin oligomerizes into a hexamer and the mutant spastin (E442Q) redistribute the wild-type spastin into filamentous microtubule

Journal of Neurochemistry

Volumn 106, Issue 2, 2008, Pages 613-624

  Pantakani, D V Krishna ^a   Swapna, Lakshmipuram S ^b   Srinivasan, Narayanaswamy ^b   Mannan, Ashraf U ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

Hereditary spastic paraplegia; Hexamer; Oligo merization; Spastin

Indexed keywords

SPASTIN; ADENOSINE TRIPHOSPHATASE; GLUTAMIC ACID; GLUTAMINE; GREEN FLUORESCENT PROTEIN; NERVE PROTEIN; NUCLEAR PROTEIN; P97 ATPASE; RTN1 PROTEIN, HUMAN; SPAST PROTEIN, HUMAN; VESICULAR TRANSPORT PROTEIN; VPS4B PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CROSS LINKING; GEL FILTRATION CHROMATOGRAPHY; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; MAMMAL CELL; MICROTUBULE; MISSENSE MUTATION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; WILD TYPE; ANIMAL; CELL STRAIN 3T3; CHEMICAL STRUCTURE; CHEMISTRY; GEL CHROMATOGRAPHY; GENETIC TRANSFECTION; GENETICS; METABOLISM; METHODOLOGY; MOUSE; MUTATION; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT;

MAMMALIA;

ADENOSINE TRIPHOSPHATASES; ANIMALS; CHROMATOGRAPHY, GEL; GLUTAMIC ACID; GLUTAMINE; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOPRECIPITATION; MICE; MICROTUBULES; MODELS, MOLECULAR; MUTATION; NERVE TISSUE PROTEINS; NIH 3T3 CELLS; NUCLEAR PROTEINS; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; TRANSFECTION; VESICULAR TRANSPORT PROTEINS;

EID: 51649113752     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05414.x     Document Type: Article

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