Protoporphyrin IX fluorescence photobleaching increases with the use of fractionated irradiation in the esophagus

Journal of Biomedical Optics

Volumn 13, Issue 3, 2008, Pages

  Pogue, Brian W ^a,b,c   Sheng, Chao ^a   Benevides, Juan ^b   Forcione, David ^b   Puricelli, Bill ^c   Nishioka, Norm ^c,d   Hasan, Tayyaba ^c  

^a DARTMOUTH COLLEGE   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d Department of Medicine ^*  (United States)

Author keywords

fiber optic sensors; fiber optics; fluorescence; photodetection; photodynamic therapy; targets

Indexed keywords

ALA-PPIX; BARRETT'S ESOPHAGUS; BENEFICIAL EFFECTS; BLEACHING YIELD; DATA SUPPORT; DEPOSITED DOSE; FLUORESCENCE MEASUREMENTS; FRACTIONATED IRRADIATION; IN-VIVO MEASUREMENT; LIGHT DELIVERY; OPTIMAL TREATMENT; P-VALUES; PHOTO DETECTION; PROTOPORPHYRIN IX; TREATMENT EFFECTS;

BLEACHING; CLEANING; DOSIMETRY; FIBER OPTIC SENSORS; LIGHT; PHOTOBLEACHING; PHOTODYNAMIC THERAPY; PLASMONS; RATS; TISSUE;

FLUORESCENCE;

RATTUS;

PROTOPORPHYRIN;

ANIMAL; ARTICLE; BEHCET DISEASE; BLEACHING; DOSE RESPONSE; DRUG EFFECT; ESOPHAGUS; METABOLIC CLEARANCE RATE; METABOLISM; METHODOLOGY; PROGNOSIS; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RADIATION EXPOSURE; RAT; SPECTROFLUOROMETRY; SPRAGUE DAWLEY RAT; TREATMENT OUTCOME;

ANIMALS; BEHCET SYNDROME; DOSE FRACTIONATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ESOPHAGUS; METABOLIC CLEARANCE RATE; PHOTOBLEACHING; PROGNOSIS; PROTOPORPHYRINS; RADIOTHERAPY DOSAGE; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, FLUORESCENCE; TREATMENT OUTCOME;

EID: 51649105411     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.2937476     Document Type: Article

References (19)

1. C., Sheng, P. J., Hoopes, T., Hasan, and B. W., Pogue, " Photobleaching-based dosimetry predicts deposited dose in ALA-PpIX PDT of rodent esophagus, ", Photochem. Photobiol., 83, 738-748 (2007). pho PHCBAP 0031-8655
2. I., Georgakoudi and T. H., Foster, " Singlet oxygen- versus nonsinglet oxygen-mediated mechanisms of sensitizer photobleaching and their effects on photodynamic dosimetry, ", Photochem. Photobiol., 67 (6), 612-625 (1998). pho PHCBAP 0031-8655 10.1111/j.1751-1097.1998.tb09463.x
3. D. J., Robinson, H. S., de Bruijn, N., van der Veen, M. R., Stringer, S. B., Brown, and W. M., Star, " Protoporphyrin IX fluorescence photobleaching during ALA-mediated photodynamic therapy of UVB-induced tumors in hairless mouse skin, ", Photochem. Photobiol., 69 (1), 61-70 (1999). pho PHCBAP 0031-8655 10.1111/j.1751-1097.1999.tb05307.x
4. D. J., Robinson, H. S., de Bruijn, N., van der Veen, M. R., Stringer, S. B., Brown, and W. M., Star, " Fluorescence photobleaching of ALA-induced protoporphyrin IX during photodynamic therapy of normal hairless mouse skin: the effect of light dose and irradiance and the resulting biological effect, ", Photochem. Photobiol., 67 (1), 140-149 (1998). pho PHCBAP 0031-8655 10.1111/j.1751-1097.1998.tb05177.x
5. J., Moan, Q., Peng, R., Sorensen, V., Iani, and J. M., Nesland, " The biophysical foundations of photodynamic therapy, ", Endoscopy, 30 (4), 387-391 (1998). 4jf ZZZZZZ 0013-726X
6. I. A., Boere, D. J., Robinson, H. S., de Bruijn, J., Kluin, H. W., Tilanus, H. J. C. M., Sterenborg, and R. W. F., de Bruin, " Protoporphyrin IX fluorescence photobleaching and the response of rat Barrett's esophagus following 5-aminolevulinic acid photodynamic therapy, ", Photochem. Photobiol., 82 (6), 1638-1644 (2006). pho PHCBAP 0031-8655
7. D. E., Hyde, T. J., Farrell, M. S., Patterson, and B. C., Wilson, " A diffusion theory model of spatially resolved fluorescence from depth-dependent fluorophore concentrations, ", Phys. Med. Biol., 46 (2), 369-383 (2001). pme PHMBA7 0031-9155 10.1088/0031-9155/46/2/307
8. P., Juzenas, A., Juzeniene, O., Kaalhus, V., Iani, and J., Moan, " Noninvasive fluorescence excitation spectroscopy during application of 5-aminolevulinic acid in vivo, ", Photochem. Photobiol. Sci., 1 (10), 745-748 (2002). bk8 PPSHCB 1474-905X
9. B. W., Pogue, S. L., Gibbs, B., Chen, and M., Savellano, " Fluorescence imaging in vivo: raster scanned point-source imaging provides more accurate quantification than broad beam geometries, ", Technol. Cancer Res. Treat., 3 (1), 15-21 (2004). bbo TCRTBS 1533-0346
10. B. W., Pogue, G., Burke, C. C., Lee, and P. J., Hoopes, " Photosensitizer quantitation in vivo by fluorescence micro-sampling, ", Proc. SPIE, 3914, 33-39 (2000). spi PSISDG 0277-786X
11. B. W., Pogue and G. C., Burke, " Fiber optic bundle design for quantitative fluorescence measurement from tissue, ", Appl. Opt., 37 (31), 7429-7436 (1998). apo APOPAI 0003-6935 10.1364/AO.37.007429
12. J., Hewett, V., Nadeau, J., Ferguson, H., Moseley, S., Ibbotson, J. W., Allen, W., Sibbett, and M., Padgett, " The application of a compact multispectral imaging system with integrated excitation source to in vivo monitoring of fluorescence during topical photodynamic therapy of superficial skin cancers, ", Photochem. Photobiol., 73 (3), 278-282 (2001). pho PHCBAP 0031-8655 10.1562/0031-8655(2001)073<0278:TAOACM>2.0.CO;2
13. V., Nadeau, M., O'Dwyer, K., Hamdan, I., Tait, and M., Padgett, " In vivo measurement of 5-aminolaevulinic acid-induced protoporphyrin IX photobleaching: a comparison of red and blue light of various intensities, ", Photodermatol. Photoimmunol. Photomed., 20 (4), 170-174 (2004). 3da PPPHEW 0905-4383 10.1111/j.1600-0781.2004.00100.x
14. C. D., Sudworth, M. R., Stringer, J. E., Cruse-Sawyer, and S. B., Brown, " Fluorescence microspectroscopy technique for the study of intracellular protoporphyrin IX dynamics, ", Appl. Spectrosc., 57 (6), 682-688 (2003). aps APSPA4 0003-7028 10.1366/000370203322005382
15. C. C., Lee, B. W., Pogue, G. C., Burke, and P. J., Hoopes, " Comparison of photosensitizer (AlS2Pc) quantitation techniques: in situ fluorescence microsampling versus tissue chemical extraction, ", Photochem. Photobiol., 74 (3), 453-460 (2001). pho PHCBAP 0031-8655 10.1562/0031- 8655(2001)074<0453:COPAQT>2.0.CO;2
16. C., Sheng, B. W., Pogue, E., Wang, J. E., Hutchins, and P. J., Hoopes, " Assessment of photosensitizer dosimetry and tissue damage assay for photodynamic therapy in advanced-stage tumors, ", Photochem. Photobiol., 79 (6), 520-525 (2004). pho PHCBAP 0031-8655 10.1562/MU-03-33.1
17. B. W., Pogue, B., Chen, X., Zhou, and P. J., Hoopes, " Analysis of sampling volume and tissue heterogeneity upon the in vivo detection of fluorescence, ", J. Biomed. Opt., 10, 041206 (2005). jbo JBOPFO 1083-3668 10.1117/1.2002978
18. X., Zhou, B. W., Pogue, B., Chen, and T., Hasan, " Analysis of effective molecular diffusion rates for verteporfin in subcutaneous versus orthotopic Dunning prostate tumors, ", Photochem. Photobiol., 79 (4), 323-331 (2004). pho PHCBAP 0031-8655 10.1562/MU-03-31.1
19. C. C., Lee, B. W., Pogue, J. A., O'Hara, C. M., Wilmot, R. R., Strawbridge, G. C., Burke, and P. J., Hoopes, " Spatial heterogeneity and temporal kinetics of photosensitizer (AlPcS2) concentration in murine tumors RIF-1 and MTG-B, ", Photochem. Photobiol. Sci., 2 (2), 145-150 (2003). bk8 PPSHCB 1474-905X 10.1039/b207598a