Analysis of sampling volume and tissue heterogeneity on the in vivo detection of fluorescence

Journal of Biomedical Optics

Volumn 10, Issue 4, 2005, Pages

  Pogue, Brian W ^a   Chen, Bin ^a,b   Zhou, Xiaodong ^a   Hoopes, P Jack ^a,b  

^a DARTMOUTH COLLEGE   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

Cancer; Fluorescence; Heterogeneity; Microscopy; Photodynamic; Photosensitizer

Indexed keywords

PORPHYRIN;

ALGORITHM; ANIMAL; ARTICLE; COMPARATIVE STUDY; COMPUTER ASSISTED DIAGNOSIS; EVALUATION; FLUORESCENCE MICROSCOPY; IMAGE ENHANCEMENT; MALE; METABOLISM; METHODOLOGY; PATHOLOGY; PROSTATE TUMOR; RAT; REPRODUCIBILITY; SAMPLE SIZE; SENSITIVITY AND SPECIFICITY; TUMOR CELL LINE;

ALGORITHMS; ANIMALS; CELL LINE, TUMOR; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MALE; MICROSCOPY, FLUORESCENCE; PORPHYRINS; PROSTATIC NEOPLASMS; RATS; REPRODUCIBILITY OF RESULTS; SAMPLE SIZE; SENSITIVITY AND SPECIFICITY;

FLUORESCENCE; NORMAL DISTRIBUTION; OPTICAL MICROSCOPY; PHOTOSENSITIZERS; SAMPLING; TISSUE; TUMORS;

FLUORESCENCE HISTOGRAM ASSESSMENT; FLUORESCENCE INTENSITY HISTOGRAM DISTRIBUTIONS; TISSUE HETEROGENEITY;

MEDICAL IMAGING;

EID: 32944462267     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.2002978     Document Type: Article

References (38)

1. A. E. Profio and J. Sarnaik, "Fluorescence of HpD for tumor detection and dosimetry in photoradiation therapy," in Porphyrin Localization and Treatment of Tumors, J. G. D. Doiron, Ed., pp. 301-314, Alan R. Liss, New York (1984).
2. M. Panjehpour, R. E. Sneed, D. L. Frazier, M. A. Barnhill, S. F. O'Brien, W. Harb, and B. F. Overholt, "Quantification of phthalocyanine concentration in rat tissue using laser-induced fluorescence spectroscopy," Lasers Surg. Med. 13(1), 23-30 (1993). (Pubitemid 23081958)
3. C. M. Gardner, S. L. Jacques, and A. J. Welch, "Fluorescence spectroscopy of tissue: recovery of intrinsic fluorescence from measured fluorescence," Appl. Opt. 35(10), 1780-1792 (1996). (Pubitemid 126642600)
4. S. Andersson-Engels, C. Klinteberg, K. Svanberg, and S. Svanberg, "In vivo fluorescence imaging for tissue diagnostics," Phys. Med. Biol. 42(5), 815-824 (1997). (Pubitemid 27263502)
5. B. W. Pogue, S. L. Gibbs, B. Chen, and M. Savellano, "Fluorescence imaging in vivo: raster scanned point-source imaging provides more accurate quantification than broad beam geometries," Technol. Cancer Res. Treat. 3(1), 15-21 (2004). (Pubitemid 38250464)
6. C. C. Lee, B. W. Pogue, J. A. O'Hara, C. M. Wilmot, R. R. Strawbridge, G. C. Burke, and P. J. Hoopes, "Spatial heterogeneity and temporal kinetics of photosensitizer (AlPcS2) concentration in murine tumors RIF-1 and MTG-B," Photochem. Photobiol. Sci. 2(2), 145-150 (2003). (Pubitemid 41646731)
7. Q. Peng, J. Moan, G. Farrants, H. E. Danielsen, and C. Rimington, "Localization of potent photosensitizers in human tumor LOX by means of laser scanning microscopy," Cancer Lett. 58(1,2), 17-27 (1991).
8. N. S. Trivedi, H. W. Wang, A. L. Nieminen, N. L. Oleinick, and J. A. Izatt, "Quantitative analysis of Pc 4 localization in mouse lymphoma (LY-R) cells via double-label confocal fluorescence microscopy," Photochem. Photobiol. 71(5), 634-639 (2000).
9. S. Iinuma, K. T. Schomacker, G. Wagnieres, M. Rajadhyaksha, M. Bamberg, T. Momma, and T. Hasan, "In vivo fluence rate and fractionation effects on tumor response and photobleaching: photodynamic therapy with two photosensitizers in an orthotopic rat tumor model," Cancer Res. 59(24), 6164-6170 (1999). (Pubitemid 30035638)
10. S. Andersson-Engels and B. C. Wilson, "In vivo fluorescence in clinical oncology: fundamentals and practical issues," J. Cell Pharmacol 3, 48-61 (1991).
11. L. Lilge, C. O'Carroll and B. C. Wilson, "A solubilization technique for photosensitizer quantification in ex vivo tissue samples," J. Photochem. Photobiol, B 39(3), 229-235 (1997). (Pubitemid 27356834)
12. G. J. Smith, "The effects of aggregation on the fluorescence and the triplet state yield of hematoporphyrin," Photochem. Photobiol. 41, 123-126 (1985).
13. B. Aveline, T. Hasan, and R. W. Redmond, "Photophysical and photosensitizing properties of benzoporphyrin derivative monoacid ring A (BPD-MA)," Photochem. Photobiol. 59(3), 328-335 (1994). (Pubitemid 2065507)
14. B. M. Aveline, T. Hasan, and R. W. Redmond, "The effects of aggregation, protein binding and cellular incorporation on the photophysical properties of benzoporphyrin derivative monoacid ring A (BPDMA)," J. Photochem. Photobiol, B 30(2,3), 161-169 (1995).
15. J. Moan, H. Anholt, and Q. Peng, "A transient reduction of the fluorescence of aluminium phthalocyanine tetrasulphonate in tumours during photodynamic therapy," J. Photochem. Photobiol., B 5(1), 115-119 (1990).
16. B. M. Aveline, T. Hasan, and R. W. Redmond, "The effects of aggregation, protein binding and cellular incorporation on the photophysical properties of benzoporphyrin derivative monoacid ring A (BPDMA)," J. Photochem. Photobiol., B 30, 161-169 (1995).
17. B. M. Aveline and R. W. Redmond, "Can cellular phototoxicity be accurately predicted on the basis of sensitizer photophysics?" Photochem. Photobiol. 69(3), 306-316 (1999). (Pubitemid 129554856)
18. B. M. Aveline, R. M. Sattler, and R. W. Redmond, "Environmental effects on cellular photosensitization: Correlation of phototoxicity mechanism with transient absorption spectroscopy measurements," Photochem. Photobiol. 68(1), 50-61 (1998).
19. B. C. Wilson, M. S. Patterson, and L. Lilge, "Implicit and explicit dosimetry in photodynamic therapy: a new paradigm," Lasers Med. Sci. 12, 182-199 (1997). (Pubitemid 27404122)
20. B. W Pogue, and G. C. Burke, "Fiber optic bundle design for quantitative fluorescence measurement from tissue," Appl. Opt. 37(31), 7429-7436 (1998). (Pubitemid 128659489)
21. C. C. Lee, B. W Pogue, G. C. Burke, and P. J. Hoopes, "Comparison of photosensitizer (AlS2Pc) quantitation techniques: In situ fluorescence microsampling versus tissue chemical extraction," Photochem. Photobiol. 74(3), 453-460 (2001).
22. B. W Pogue and T. Hasan, "Fluorophore quantitation in tissuesimulating media with confocal detection," IEEE J. Quantum Electron. 2(4), 959-964 (1996). (Pubitemid 126543837)
23. C. Sheng, B. W. Pogue, E. Wang, J. E. Hutchins, and P. J. Hoopes, "Assessment of photosensitizer dosimetry and tissue damage assay for photodynamic therapy in advanced-stage tumors," Photochem. Photobiol. 79(6), 520-525 (2004).
24. A. M. Richter, B. Kelly, J. Chow, D. J. Liu, G. H. Towers, D. Dolphin, and J. G. Levy, "Preliminary studies on a more effective phototoxic agent than hematoporphyrin," JNCI, J. Natl. Cancer Inst. 79(6), 1327-1332 (1987). (Pubitemid 18036738)
25. A. M. Richter, S. Cerruti-Sola, E. D. Sternberg, D. Dolphin, and J. G Levy, "Biodistribution of tritiated benzoporphyrin derivative (3HBPD-MA), a new potent photosensitizer, in normal and tumor-bearing mice," J. Photochem. Photobiol, B 5(2), 231-244 (1990).
26. B. Chen, B. W. Pogue, I. A. Goodwin, J. A. O'Hara, C. M. Wilmot, J. E. Hutchins, P. J. Hoopes, and T. Hasan, "Blood flow dynamics after photodynamic therapy with verteporfin in the RIF-1 tumor," Radiat. Res. 160(4), 452-459 (2003). (Pubitemid 37174513)
27. C. C. Lee, B. W Pogue, G. C. Burke, and P. J. Hoopes, "Spatial heterogeneity and temporal kinetics of photosensitizer (AlPcS2) concentration in murine tumors RIF-1 and MTG-B," Photochem. Photobiol. Sci. 2, 145-150 (2003). (Pubitemid 41646731)
28. X. Zhou, B. W Pogue, B. Chen, and T. Hasan, "Analysis of effective molecular diffusion rates for verteporfin in subcutaneous versus orthotopic Dunning prostate tumors," Photochem. Photobiol. 79(4), 323-331 (2004).
29. G. Helmlinger, F Yuan, M. Dellian, and R. K. Jain, "Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation," Nat. Med. 3(2), 177-182 (1997). (Pubitemid 27064702)
30. M. R. Horsman, A. A. Khalil, D. W. Siemann, C. Grau, S. A. Hill, E. M. Lynch, D. J. Chaplin, and J. Overgaard, "Relationship between radiobiological hypoxia in tumors and electrode measurements of tumor oxygenation," Int. J. Radiat. Oncol, Biol, Phys. 29(3), 439-442 (1994). (Pubitemid 24187906)
31. B. C. Wilson, M. S. Patterson, and D. M. Burns, "Effect of photosensitizer concentration in tissue on the penetration depth of photoactivating light," Lasers Med. Sci. 1, 235-244 (1986).
32. C. J. Tralau, A. J. MacRobert, P. D. Coleridge-Smith, H. Barr, and S. G Bown, "Photodynamic therapy with phthalocyanine sensitisation: quantitative studies in a transplantable rat fibrosarcoma," Br. J. Cancer 55(4), 389-395 (1987). (Pubitemid 17080798)
33. M. S. Patterson, B. C. Wilson, and R. Graff, "In vivo tests of the concept of photodynamic threshold dose in normal rat liver photosensitized by aluminum chlorosulphonated phthalocyanine," Photochem. Photobiol. 51(3), 343-349 (1990).
34. T. J. Farrell, B. C. Wilson, M. S. Patterson, and R. Chow, "The dependence of photodynamic threshold dose on treatment parameters in normal rat liver in vivo," Proc. SPIE 1426, 146-155 (1991). (Pubitemid 21714102)
35. B. W Pogue, K. D. Paulsen, J. A. O'Hara, C. M. Wilmot, and H. M. Swartz, "Estimation of oxygen distribution in RIF-1 tumors by diffusion model-based interpretation of pimonidazole hypoxia and eppendorf measurements," Radiat. Res. 155(1 Pt 1), 15-25 (2001). (Pubitemid 32125735)
36. V. H. Fingar, T. J. Wieman, Y. J. Park, and B. W. Henderson, "Implications of a preexisting tumor hypoxic fraction on photodynamic therapy," J. Surg. Res. 53(5), 524-528 (1992). (Pubitemid 23003068)
37. M. Hockel, C. Knoop, K. Schlenger, B. Vorndran, E. Baussmann, M. Mitze, P. G. Knapstein, and P. Vaupel, "Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix," Radiother. Oncol. 26(1), 45-50 (1993). (Pubitemid 23063609)
38. M. Hockel, K. Schlenger, B. Aral, M. Mitze, U. Schaffer, and P. Vaupel, "Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix," Cancer Res. 56(19), 4509-4515 (1996). (Pubitemid 26330463)