Numbness in clinical and experimental pain - A cross-sectional study exploring the mechanisms of reduced tactile function

Pain

Volumn 139, Issue 1, 2008, Pages 73-81

  Geber, Christian ^a,b   Magerl, Walter ^b,c   Fondel, Ricarda ^a   Fechir, Marcel ^a   Rolke, Roman ^a   Vogt, Thomas ^a   Treede, Rolf Detlef ^c   Birklein, Frank ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Central plasticity; Experimental pain; Mechanical hyperalgesia; Myofascial pain; Neuropathic pain; Tactile hypaesthesia

Indexed keywords

CAPSAICIN;

ADULT; AGED; ARTICLE; CHRONIC PAIN; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; ELECTROSTIMULATION; FEMALE; FOREARM; HAND PARESTHESIA; HUMAN; HYPERALGESIA; HYPERESTHESIA; MALE; MUSCULOSKELETAL PAIN; NEUROPATHIC PAIN; NOCICEPTIVE STIMULATION; PAIN ASSESSMENT; PAIN THRESHOLD; PRIORITY JOURNAL; TACTILE DISCRIMINATION;

ADULT; AGED; CROSS-SECTIONAL STUDIES; ELECTRIC STIMULATION; FEMALE; HUMANS; HYPESTHESIA; MALE; MIDDLE AGED; PAIN; PAIN MEASUREMENT; TOUCH;

EID: 51549101835     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2008.03.006     Document Type: Article

References (54)

1. Apkarian A.V., Stea R.A., and Bolanowski S.J. Heat-induced pain diminishes vibrotactile perception: a touch gate. Somatosens Mot Res 11 (1994) 259-267
2. Bauer E.P., and LeDoux J.E. Heterosynaptic long-term potentiation of inhibitory interneurons in the lateral amygdala. J Neurosci 24 (2004) 9507-9512
3. Birklein F., Riedl B., Sieweke N., Weber M., and Neundorfer B. Neurological findings in complex regional pain syndromes-analysis of 145 cases. Acta Neurol Scand 101 (2000) 262-269
4. Buchner H., Richrath P., Grunholz J., Noppeney U., Waberski T.D., Gobbele R., et al. Differential effects of pain and spatial attention on digit representation in the human primary somatosensory cortex. Neuroreport 11 (2000) 1289-1293
5. Calford M.B., and Tweedale R. C-fibres provide a source of masking inhibition to primary somatosensory cortex. Proc Biol Sci 243 (1991) 269-275
6. Cervero F., Laird J.M., and Garcia-Nicas E. Secondary hyperalgesia and presynaptic inhibition: an update. Eur J Pain 7 (2003) 345-351
7. Driver J., and Spence C. Crossmodal attention. Curr Opin Neurobiol 8 (1998) 245-253
8. Duncan J., Martens S., and Ward R. Restricted attentional capacity within but not between sensory modalities. Nature 387 (1997) 808-810
9. Dykes R.W., and Craig A.D. Control of size and excitability of mechanosensory receptive fields in dorsal column nuclei by homolateral dorsal horn neurons. J Neurophysiol 80 (1998) 120-129
10. Flor H., Elbert T., Knecht S., Wienbruch C., Pantev C., Birbaumer N., et al. Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation. Nature 375 (1995) 482-484
11. Freynhagen R., Rolke R., Baron R., Tolle T.R., Rutjes A.K., Schu S., et al. Pseudoradicular and radicular low-back pain - A disease continuum rather than different entities? Answers from quantitative sensory testing. Pain 137 (2008) 230-231
12. Fruhstorfer H., Gross W., and Selbmann O. von Frey hairs: new materials for a new design. Eur J Pain 5 (2001) 341-342
13. Geber C., Fondel R., Kramer H.H., Rolke R., Treede R.D., Sommer C., et al. Psychophysics, flare, and neurosecretory function in human pain models: capsaicin versus electrically evoked pain. J Pain 8 (2007) 503-514
14. Glass G.V., and Stanley J.C. Statistical methods in education and psychology. (1970)
15. Graven-Nielsen T., Arendt-Nielsen L., Svensson P., and Jensen T.S. Quantification of local and referred muscle pain in humans after sequential i.m. injections of hypertonic saline. Pain 69 (1997) 111-117
16. Hendiani J.A., Westlund K.N., Lawand N., Goel N., Lisse J., and McNearney T. Mechanical sensation and pain thresholds in patients with chronic arthropathies. J Pain 4 (2003) 203-211
17. Janig W., and Zimmermann M. Presynaptic depolarization of myelinated afferent fibres evoked by stimulation of cutaneous C fibres. J Physiol 214 (1971) 29-50
18. Klede M., Handwerker H.O., and Schmelz M. Central origin of secondary mechanical hyperalgesia. J Neurophysiol 90 (2003) 353-359
19. Koltzenburg M., Lundberg L.E., and Torebjork H.E. Dynamic and static components of mechanical hyperalgesia in human hairy skin. Pain 51 (1992) 207-219
20. Koltzenburg M., Torebjork H.E., and Wahren L.K. Nociceptor modulated central sensitization causes mechanical hyperalgesia in acute chemogenic and chronic neuropathic pain. Brain 117 Pt 3 (1994) 579-591
21. Koltzenburg M., Wall P.D., and McMahon S.B. Does the right side know what the left is doing?. Trends Neurosci 22 (1999) 122-127
22. Koppert W., Dern S.K., Sittl R., Albrecht S., Schuttler J., and Schmelz M. A new model of electrically evoked pain and hyperalgesia in human skin: the effects of intravenous alfentanil, S(+)-ketamine, and lidocaine. Anesthesiology 95 (2001) 395-402
23. Koppert W., Ihmsen H., Korber N., Wehrfritz A., Sittl R., Schmelz M., et al. Different profiles of buprenorphine-induced analgesia and antihyperalgesia in a human pain model. Pain 118 (2005) 15-22
24. Kosek E., and Hansson P. The influence of experimental pain intensity in the local and referred pain area on somatosensory perception in the area of referred pain. Eur J Pain 6 (2002) 413-425
25. LaMotte R.H., Shain C.N., Simone D.A., and Tsai E.F. Neurogenic hyperalgesia: psychophysical studies of underlying mechanisms. J Neurophysiol 66 (1991) 190-211
26. Le Bars D. The whole body receptive field of dorsal horn multireceptive neurones. Brain Res Brain Res Rev 40 (2002) 29-44
27. Leffler A.S., Hansson P., and Kosek E. Somatosensory perception in patients suffering from long-term trapezius myalgia at the site overlying the most painful part of the muscle and in an area of pain referral. Eur J Pain 7 (2003) 267-276
28. Leffler A.S., Kosek E., and Hansson P. The influence of pain intensity on somatosensory perception in patients suffering from subacute/chronic lateral epicondylalgia. Eur J Pain 4 (2000) 57-71
29. Leffler A.S., Kosek E., and Hansson P. Injection of hypertonic saline into musculus infraspinatus resulted in referred pain and sensory disturbances in the ipsilateral upper arm. Eur J Pain 4 (2000) 73-82
30. Magerl W., and Treede R.D. Secondary tactile hypoesthesia: a novel type of pain-induced somatosensory plasticity in human subjects. Neurosci Lett 361 (2004) 136-139
31. Magerl W., Wilk S.H., and Treede R.D. Secondary hyperalgesia and perceptual wind-up following intradermal injection of capsaicin in humans. Pain 74 (1998) 257-268
32. Maihofner C., Handwerker H.O., Neundorfer B., and Birklein F. Cortical reorganization during recovery from complex regional pain syndrome. Neurology 63 (2004) 693-701
33. Moriwaki K., and Yuge O. Topographical features of cutaneous tactile hypoesthetic and hyperesthetic abnormalities in chronic pain. Pain 81 (1999) 1-6
34. Nathan P.W. Improvement in cutaneous sensibility associated with relief of pain. J Neurol Neurosurg Psychiatry 23 (1960) 202-206
35. Ochoa J.L., and Yarnitsky D. Mechanical hyperalgesias in neuropathic pain patients: dynamic and static subtypes. Ann Neurol 33 (1993) 465-472
36. Park K.M., Max M.B., Robinovitz E., Gracely R.H., and Bennett G.J. Effects of intravenous ketamine, alfentanil, or placebo on pain, pinprick hyperalgesia, and allodynia produced by intradermal capsaicin in human subjects. Pain 63 (1995) 163-172
37. Pleger B., Tegenthoff M., Ragert P., Forster A.F., Dinse H.R., Schwenkreis P., et al. Sensorimotor retuning [corrected] in complex regional pain syndrome parallels pain reduction. Ann Neurol 57 (2005) 425-429
38. Ploner M., Gross J., Timmermann L., and Schnitzler A. Pain processing is faster than tactile processing in the human brain. J Neurosci 26 (2006) 10879-10882
39. Rolke R., Baron R., Maier C., Tolle T.R., Treede R.D., Beyer A., et al. Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): standardized protocol and reference values. Pain 123 (2006) 231-243
40. Rolke R., Magerl W., Campbell K.A., Schalber C., Caspari S., Birklein F., et al. Quantitative sensory testing: a comprehensive protocol for clinical trials. Eur J Pain 10 (2006) 77-88
41. Rozas J.L., Paternain A.V., and Lerma J. Noncanonical signaling by ionotropic kainate receptors. Neuron 39 (2003) 543-553
42. Schlereth T., Baumgartner U., Magerl W., Stoeter P., and Treede R.D. Left-hemisphere dominance in early nociceptive processing in the human parasylvian cortex. Neuroimage 20 (2003) 441-454
43. Seminowicz D.A., and Davis K.D. A re-examination of pain-cognition interactions: implications for neuroimaging. Pain 130 (2007) 8-13
44. Simone D.A., Baumann T.K., and LaMotte R.H. Dose-dependent pain and mechanical hyperalgesia in humans after intradermal injection of capsaicin. Pain 38 (1989) 99-107
45. Simone D.A., Sorkin L.S., Oh U., Chung J.M., Owens C., LaMotte R.H., et al. Neurogenic hyperalgesia: central neural correlates in responses of spinothalamic tract neurons. J Neurophysiol 66 (1991) 228-246
46. Simons D.G., and Travell J. Myofascial trigger points, a possible explanation. Pain 10 (1981) 106-109
47. Simons DG, Travell JG. Myofascial origins of low back pain. 1. Principles of diagnosis and treatment. Postgrad Med 1983;73:66, 68-70, 73 passim.
48. Stein C., and Mendl G. The German counterpart to McGill Pain Questionnaire. Pain 32 (1988) 251-255
49. Torebjork H.E., Lundberg L.E., and LaMotte R.H. Central changes in processing of mechanoreceptive input in capsaicin-induced secondary hyperalgesia in humans. J Physiol 448 (1992) 765-780
50. Treede R.D., Handwerker H.O., Baumgärtner U., Meyer R.A., and Magerl W. Hyperalgesia and Allodynia: Taxonomy, Assessment, and Mechanisms (2004), IASP Press, Seattle
51. Treede RD, Jensen TS, Campbell JN, Gruccu G, Dostrovsky JO, Griffin JW, et al. Neuropathic pain: redefinition and agrading system for clinical and research purposes. Neurology, in press, 0:01.wnl.0000282763.29778.59.
52. Treede R.D., Meyer R.A., Raja S.N., and Campbell J.N. Peripheral and central mechanisms of cutaneous hyperalgesia. Prog Neurobiol 38 (1992) 397-421
53. Verdugo R.J., and Ochoa J.L. Reversal of hypaesthesia by nerve block, or placebo: a psychologically mediated sign in chronic pseudoneuropathic pain patients. J Neurol Neurosurg Psychiatry 65 (1998) 196-203
54. Ziegler E.A., Magerl W., Meyer R.A., and Treede R.D. Secondary hyperalgesia to punctate mechanical stimuli. Central sensitization to A-fibre nociceptor input. Brain 122 Pt 12 (1999) 2245-2257