Pain processing is faster than tactile processing in the human brain

Journal of Neuroscience

Volumn 26, Issue 42, 2006, Pages 10879-10882

  Ploner, Markus ^a   Gross, Joachim ^a   Timmermann, Lars ^a   Schnitzler, Alfons ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Magnetoencephalography; Nociception; Pain; Reaction times; Somatosensory cortices; Touch

Indexed keywords

ADULT; ARTICLE; BEHAVIOR; CONTROLLED STUDY; HUMAN; MAGNETOENCEPHALOGRAPHY; MALE; NERVE CONDUCTION; NOCICEPTION; NORMAL HUMAN; PRIORITY JOURNAL; REACTION TIME; STIMULUS RESPONSE; TOUCH; BRAIN; BRAIN CORTEX; COMPARATIVE STUDY; METHODOLOGY; PAIN; PAIN ASSESSMENT; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADULT; BRAIN; CEREBRAL CORTEX; HUMANS; MALE; PAIN; PAIN MEASUREMENT; REACTION TIME; TOUCH;

EID: 33750957546     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2386-06.2006     Document Type: Article

References (28)

1. Arendt-Nielsen L, Bjerring P (1988) Reaction times to painless and painful CO2 and argon laser stimulation. Eur J Appl Physiol Occup Physiol 58:266-273.
2. Binkofski F, Buccino G, Posse S, Seitz RJ, Rizzolatti G, Freund H (1999) A fronto-parietal circuit for object manipulation in man: evidence from an fMRI-study. Eur J Neurosci 11:3276-3286.
3. Brebner JMT, Welford AT (1980) Introduction: an historical background sketch. In: Reaction times (Welford AT, ed), pp 1-23. London: Academic.
4. Bromm B, Treede RD (1984) Nerve fibre discharges, cerebral potentials and sensations induced by CO2 laser stimulation. Hum Neurobiol 3:33-40.
5. Bushnell MC, Apkarian AV (2006) Representation of pain in the brain. In: Wall and Melzack's textbook of pain (McMahon SB, Koltzenburg M, eds), pp 107-124. Philadelphia: Elsevier.
6. Campbell JN, LaMotte RH (1983) Latency to detection of first pain. Brain Res 266:203-208.
7. Craig AD (2003) Pain mechanisms: labeled lines versus convergence in central processing. Annu Rev Neurosci 26:1-30.
8. Disbrow E, Litinas E, Recanzone GH, Padberg J, Krubitzer L (2003) Cortical connections of the second somatosensory area and the parietal ventral area in macaque monkeys. J Comp Neurol 462:382-399.
9. Dostrovsky JO, Craig AD (2006) Ascending projection systems. In: Wall and Melzack's textbook of pain (McMahon SB, Koltzenburg M, eds), pp 187-203. Philadelphia: Elsevier.
10. Ferrington DG, Sorkin LS, Willis Jr WD (1987) Responses of spinothalamic tract cells in the superficial dorsal horn of the primate lumbar spinal cord. J Physiol (Lond) 388:681-703.
11. Forss N, Jousmaki V (1998) Sensorimotor integration in human primary and secondary somatosensory cortices. Brain Res 781:259-267.
12. Hämäläinen M, Hari R, Ilmoniemi RJ, Knuutila J, Lounasmaa OV (1993) Magnetoencephalography: theory, instrumentation, and applications to noninvasive studies of the working human brain. Rev Mod Phys 65:413-497.
13. Hari R, Forss N (1999) Magnetoencephalography in the study of human somatosensory cortical processing. Philos Trans R Soc Lond B Biol Sci 354:1145-1154.
14. Huttunen J, Wikstrom H, Korvenoja A, Seppalainen AM, Aronen H, Ilmoniemi RJ (1996) Significance of the second somatosensory cortex in sensorimotor integration: enhancement of sensory responses during finger movements. NeuroReport 7:1009-1012.
15. Inui K, Tran TD, Qiu Y, Wang X, Hoshiyama M, Kakigi R (2003) A comparative magnetoencephalographic study of cortical activations evoked by noxious and innocuous somatosensory stimulations. Neuroscience 120:235-248.
16. Kaas JH (2004) Somatosensory system. In: The human nervous system (Paxinos G, Mai JK, eds). Amsterdam: Elsevier.
17. Kakigi R, Shibasaki H (1991) Estimation of conduction velocity of the spinothalamic tract in man. Electroencephalogr Clin Neurophysiol 80:39-45.
18. Kakigi R, Inui K, Tamura Y (2005) Electrophysiological studies on human pain perception. Clin Neurophysiol 116:743-763.
19. Kanda M, Nagamine T, Ikeda A, Ohara S, Kunieda T, Fujiwara N, Yazawa S, Sawamoto N, Matsumoto R, Taki W, Shibasaki H (2000) Primary somatosensory cortex is actively involved in pain processing in human. Brain Res 853:282-289.
20. Krubitzer LA, Kaas JH (1990) The organization and connections of somatosensory cortex in marmosets. J Neurosci 10:952-974.
21. Ledberg A, O'Sullivan BT, Kinomura S, Roland PE (1995) Somatosensory activations of the parietal operculum of man. A PET study. Eur J Neurosci 7:1934-1941.
22. Meyer RA, Ringkamp M, Campbell JN, Raja SN (2006) Peripheral mechanisms of cutaneous nociception. In: Wall and Melzack's textbook of pain (McMahon SB, Koltzenburg M, eds), pp 3-34. Philadelphia: Elsevier.
23. Ohara S, Crone NE, Weiss N, Treede RD, Lenz FA (2004) Amplitudes of laser evoked potential recorded from primary somatosensory, parasylvian and medial frontal cortex are graded with stimulus intensity. Pain 110:318-328.
24. Pertovaara A, Reinikainen K, Hari R (1984) The activation of unmyelinated or myelinated afferent fibers by brief infrared laser pulses varies with skin type. Brain Res 307:341-343.
25. Ploner M, Schmitz F, Freund HJ, Schnitzler A (1999) Parallel activation of primary and secondary somatosensory cortices in human pain processing. J Neurophysiol 81:3100-3104.
26. Vallbo AB, Hagbarth KE, Torebjork HE, Wallin BG (1979) Somatosensory, proprioceptive, and sympathetic activity in human peripheral nerves. Physiol Rev 59:919-957.
27. Vogt BA, Hof PR, Vogt LJ (2004) Cingulate gyrus. In: The human nervous system (Paxinos G, Mai JK, eds), pp 915-949. Amsterdam: Elsevier.
28. Willis WD, Westlund KN (2004) Pain system. In: The human nervous system (Paxinos G, Mai JK, eds), pp 1125-1170. Amsterdam: Elsevier.