HSV-1 infection suppresses TGF-β1 and SMAD3 expression in human corneal epithelial cells

Molecular Vision

Volumn 14, Issue , 2008, Pages 1631-1638

  Nie, Yuhong ^a   Cui, Dongmei ^a   Pan, Zhujuan ^a   Deng, Jiangyun ^a   Huang, Qiang ^a   Wu, Kaili ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; CORNEA EPITHELIUM; CYTOPATHOGENIC EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; HERPES SIMPLEX VIRUS 1; HERPES VIRUS INFECTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; KERATITIS; PHASE CONTRAST MICROSCOPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CELL LINE; CELL SHAPE; EPITHELIAL CELLS; EPITHELIUM, CORNEAL; GENE EXPRESSION REGULATION; HERPESVIRUS 1, HUMAN; HUMANS; PHOSPHOPROTEINS; PROTEIN ISOFORMS; PROTEIN TRANSPORT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

EID: 51549100991     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Roizman B, Knipe DM. Herpes simplex viruses and their replication. In: Knipe DM, Howley PM, editors. Fields Virology. Philadelphia: Lippincott Raven Press; 2001. p. 2399-460.
2. Brandt CR. The role of viral and host genes in corneal infection with herpes simplex virus type 1. Exp Eye Res 2005; 80:607-21.
3. Kaye S, Choudhary A. Herpes simplex keratitis. Prog Retin Eye Res 2006; 25:355-80.
4. Hu M, Dutt J, Arrunategui-Correa V, Baltatzis S, Foster CS. Cytokine mRNA in BALB/c mouse corneas infected with herpes simplex virus. Eye 1999; 13:309-13.
5. Li H, Zhang J, Kumar A, Zheng M, Atherton SS, Yu FS. Herpes simplex virus 1 infection induces the expression of proinflammatory cytokines, interferons and TLR7 in human corneal epithelial cells. Immunology 2006; 117:167-76.
6. Tang Q. Chen W, Hendricks RL. Proinflammatory functions of IL-2 in herpes simplex virus corneal infection. J Immunol 1997; 158:1275-83.
7. Heldin CH, Miyazono K, ten Dijke P. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 1997; 390:465-71.
8. Arnulf B, Villemain A, Nicot C, Mordelet E, Charneau P, Kersual J, Zermati Y, Mauviel A, Bazarbachi A, Hermine O. Human T-cell lymphotropic virus oncoprotein Tax represses TGF-beta 1 signaling in human T cells via c-Jun activation: a potential mechanism of HTLV-I leukemogenesis. Blood 2002; 100:4129-38.
9. Lotz M, Seth P. TGF beta and HIV infection. Ann N Y Acad Sci 1993; 685:501-11.
10. Lee DY, Kim BC, Kim IY, Cho EA, Satterwhite DJ, Kim SJ. The human papilloma virus E7 oncoprotein inhibits transforming growth factor-beta signaling by blocking binding of the Smad complex to its target sequence. J Biol Chem 2002; 277:38557-64.
11. Seo T, Park J, Choe J. Kaposi's sarcoma-associated herpesvirus viral IFN regulatory factor 1 inhibits transforming growth factor-beta signaling. Cancer Res 2005; 65:1738-47.
12. Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 2003; 425:577-84.
13. ten Dijke P, Hill CS. New insights into TGF-beta-Smad signalling. Trends Biochem Sci 2004; 29:265-73.
14. Nishida K, Sotozono C, Adachi W, Yamamoto S, Yokoi N, Kinoshita S. Transforming growth factor-beta 1, -beta 2 and -beta 3 mRNA expression in human cornea. Curr Eye Res 1995; 14:235-41.
15. Wilson SE, Schultz GS, Chegini N, Weng J, He YG. Epidermal growth factor, transforming growth factor alpha, transforming growth factor beta, acidic fibroblast growth factor, basic fibroblast growth factor, and interleukin-1 proteins in the cornea. Exp Eye Res 1994; 59:63-71.
16. Hutcheon AE, Guo XQ, Stepp MA, Simon KJ, Weinreb PH, Violette SM, Zieske JD. Effect of wound type on Smad 2 and 4 translocation. Invest Ophthalmol Vis Sci 2005; 46:2362-8.
17. Tuli SS, Liu R, Chen C, Blalock TD, Goldstein M, Schultz GS. Immunohistochemical localization of EGF, TGF-alpha, TGF-beta, and their receptors in rat corneas during healing of excimer laser ablation. Curr Eye Res 2006; 31:709-19.
18. Saika S. TGF-beta signal transduction in corneal wound healing as a therapeutic target. Cornea 2004; 23:S25-30.
19. Mendez-Samperio P, Hernandez M, Ayala HE. Induction of transforming growth factor-beta 1 production in human cells by herpes simplex virus. J Interferon Cytokine Res 2000; 20:273-80.
20. Dosanjh A. Transforming growth factor-beta expression induced by rhinovirus infection in respiratory epithelial cells. Acta Biochim Biophys Sin (Shanghai) 2006; 38:911-4.
21. Grone A, Fonfara S, Baumgartner W. Cell type-dependent cytokine expression after canine distemper virus infection. Viral Immunol 2002; 15:493-505.
22. Michelson S, Alcami J, Kim SJ, Danielpour D, Bachelerie F, Picard L, Bessia C, Paya C, Virelizier JL. Human cytomegalovirus infection induces transcription and secretion of transforming growth factor beta 1. J Virol 1994; 68:5730-7.
23. Liu J, Song G, Wang Z, Huang B, Gao Q, Liu B, Xu Y, Liang X, Ma P, Gao N, Ge J. Establishment of a corneal epithelial cell line spontaneously derived from human limbal cells. Exp Eye Res 2007; 84:599-609.
24. Baumgartner WK, Metzler AE, Krakowka S, Koestner A. In vitro identification and characterization of a virus isolated from a dog with neurological dysfunction. Infect Immun 1981; 31:1177-83.
25. Cui D, Trier K, Chen X, Zeng J, Yang X, Hu J, Ge J. Distribution of adenosine receptors in human sclera fibroblasts. Mol Vis 2008; 14:523-9.
26. Xie LX. An experimental study on the susceptibility of human corneal cells to infection by herpes simplex virus type 1. Zhonghua Yan Ke Za Zhi 1991; 27:235-7.
27. Cook SD, Brown SM. Herpes simplex virus type 1 persistence and latency in cultured rabbit corneal epithelial cells, keratocytes, and endothelial cells. Br J Ophthalmol 1986; 70:642-50.
28. Balliet JW, Kushnir AS, Schaffer PA. Construction and characterization of a herpes simplex virus type I recombinant expressing green fluorescent protein: acute phase replication and reactivation in mice. Virology 2007; 361:372-83.
29. Nishida K, Kinoshita S, Yokoi N, Kaneda M, Hashimoto K, Yamamoto S. Immunohistochemical localization of transforming growth factor-beta 1, -beta 2, and -beta 3 latency-associated peptide in human cornea. Invest Ophthalmol Vis Sci 1994; 35:3289-94.
30. Saika S, Ikeda K, Yamanaka O, Miyamoto T, Ohnishi Y, Sato M, Munigaki Y, Ooshima. A, Nakajima Y, Kao WW, Flanders KC, Roberts AB. Expression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali. Am J Pathol 2005; 166:1405-18.
31. Mitsuhiro MR, Eguchi S, Yamashita H. Regulation mechanisms of retinal pigment epithelial cell migration by the TGF-beta superfamily. Acta Ophthalmol Scand 2003; 81:630-8.
32. Kekow J, Wachsman W, McCutchan JA, Cronin M, Carson DA, Lotz M. Transforming growth factor beta and noncytopathic mechanisms of immunodeficiency in human immunodeficiency virus infection. Proc Natl Acad Sci USA 1990; 87:8321-5.
33. Kossmann T, Morganti-Kossmann MC, Orenstein JM, Britt WJ, Wahl SM, Smith PD. Cytomegalovirus production by infected astrocytes correlates with transforming growth factor-beta release. J Infect Dis 2003; 187:534-41.
34. Mendoza JA, Jacob Y, Cassonnet P, Favre M. Human papillomavirus type 5 E6 oncoprotein represses the transforming growth factor beta signaling pathway by binding to SMAD3. J Virol 2006; 80:12420-4.
35. Kobayashi T, Liu X, Wen FQ, Kohyama T, Shen L, Wang XQ, Hashimoto M, Mao L, Togo S, Kawasaki S, Sugiura H, Kamio K, Rennard SI. Smad3 mediates TGF-beta1-induced collagen gel contraction by human lung fibroblasts. Biochem Biophys Res Commun 2006; 339:290-5.
36. Roberts AB, Piek E, Bottinger EP, Ashcroft G, Mitchell JB, Flanders KC. Is Smad3 a major player in signal transduction pathways leading to fibrogenesis? Chest 2001; 120:43S-7S.
37. Goodkin ML, Ting AT, Blaho JA. NF-kappaB is required for apoptosis prevention during herpes simplex virus type 1 infection. J Virol 2003; 77:7261-80.