Synthesis of enantiopure 3,6,7,8-tetrahydrochromeno[7,8-d]imidazoles via asymmetric ketone hydrogenation in the presence of RuCl2[Xyl-P-Phos][DAIPEN]

Tetrahedron Asymmetry

Volumn 19, Issue 17, 2008, Pages 2102-2110

  Palmer, Andreas Marc ^a   Chiesa, Vittoria ^a   Holst, Hans Christof ^a   Le Paih, Jacques ^b   Zanotti Gerosa, Antonio ^b   Nettekoven, Ulrike ^c  

^a Nycomed GmbH   (Germany)

^b JOHNSON MATTHEY TECHNOLOGY CENTRE   (United Kingdom)

^c SOLVIAS AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

3,6,7,8 TETRAHYDROCHROMENO[7,8 D]IMIDAZOLE DERIVATIVE; ALCOHOL; ALCOHOL DEHYDROGENASE; BYK 311319; IMIDAZOLE DERIVATIVE; KETONE; N,N,2,3 TETRAMETHYL 8 (2 METHYLPHENYL) 3,6,7,8 TETRAHYDROCHROMENO[7,8 D]IMIDAZOLE 5 CARBOXAMIDE; N,N,2,3 TETRAMETHYL 8 PHENYL 3,6,7,8 TETRAHYDROCHROMENO[7,8 D]IMIDAZOLE 5 CARBOXAMIDE; RUBIDIUM CHLORIDE; RUBIDIUM CHLORIDE CHIRAL DIPHOSPHINE 1,2 DIAMINE; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC SYNTHESIS; CANDIDA PARAPSILOSIS; CATALYST; COMPLEX FORMATION; DRUG ACTIVITY; DRUG ISOLATION; DRUG PURITY; ENANTIOMER; GASTROESOPHAGEAL REFLUX; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGENATION; LACTOBACILLUS; LACTOBACILLUS BREVIS; LACTOBACILLUS KEFIR; NONHUMAN; NOYORI TYPE COMPLEX; OUTCOMES RESEARCH; PRIORITY JOURNAL; PRODUCT RECOVERY; RHODOCOCCUS; SUBSTITUTION REACTION; THERMOANAEROBACTER; THERMOANAEROBIUM BROKII;

EID: 51449112805     PISSN: 09574166     EISSN: 1362511X     Source Type: Journal    
DOI: 10.1016/j.tetasy.2008.08.022     Document Type: Article

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