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Volumn 217, Issue 2, 2008, Pages 350-359

Lipopolysaccharide plus hypoxia and reoxygenation synergistically reduce electrical coupling between microvascular endothelial cells by dephosphorylating connexin40

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 37; CONNEXIN 40; CYCLIC AMP DEPENDENT PROTEIN KINASE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; CONNEXIN 43; ENZYME ACTIVATOR; GAP JUNCTION PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXYGEN; PROTEIN KINASE INHIBITOR;

EID: 51449107134     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21505     Document Type: Article
Times cited : (38)

References (54)
  • 1
    • 0043124556 scopus 로고    scopus 로고
    • Effects of acute hypoxia and lipopolysaccharide on nitric oxide synthase-2 expression in acute lung injury
    • Agorreta J, Garayoa M, Montuenga LM, Zulueta JJ. 2003. Effects of acute hypoxia and lipopolysaccharide on nitric oxide synthase-2 expression in acute lung injury. Am J Respir Crit Care Med 168:287-296.
    • (2003) Am J Respir Crit Care Med , vol.168 , pp. 287-296
    • Agorreta, J.1    Garayoa, M.2    Montuenga, L.M.3    Zulueta, J.J.4
  • 2
    • 0035104547 scopus 로고    scopus 로고
    • Ascorbate prevents microvascular dysfunction in the skeletal muscle of the septic rat
    • Armour J, Tyml K, Lidington D, Wilson JX. 2001. Ascorbate prevents microvascular dysfunction in the skeletal muscle of the septic rat. J Appl Physiol 90:795-803.
    • (2001) J Appl Physiol , vol.90 , pp. 795-803
    • Armour, J.1    Tyml, K.2    Lidington, D.3    Wilson, J.X.4
  • 4
    • 0033579464 scopus 로고    scopus 로고
    • Sequence and structure-based prediction of eukaryotic protein phosphorylation sites
    • Blom N, Gammeltoft S, Brunak S. 1999. Sequence and structure-based prediction of eukaryotic protein phosphorylation sites. J Mol Biol 294:1351-1362.
    • (1999) J Mol Biol , vol.294 , pp. 1351-1362
    • Blom, N.1    Gammeltoft, S.2    Brunak, S.3
  • 5
    • 2942564430 scopus 로고    scopus 로고
    • Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence
    • Blom N, Sicheritz-Ponten T, Gupta R, Gammeltoft S, Brunak S. 2004. Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence. Proteomics 4:1633-1649.
    • (2004) Proteomics , vol.4 , pp. 1633-1649
    • Blom, N.1    Sicheritz-Ponten, T.2    Gupta, R.3    Gammeltoft, S.4    Brunak, S.5
  • 6
    • 34247171377 scopus 로고    scopus 로고
    • Relationship between sublingual and intestinal microcirculatory perfusion in patients with abdominal sepsis
    • Boerma EC, van der Voort PHJ, Spronk PE, Ince C. 2007. Relationship between sublingual and intestinal microcirculatory perfusion in patients with abdominal sepsis. Crit Care Med 35:1055-1060.
    • (2007) Crit Care Med , vol.35 , pp. 1055-1060
    • Boerma, E.C.1    van der Voort, P.H.J.2    Spronk, P.E.3    Ince, C.4
  • 7
    • 26444579849 scopus 로고    scopus 로고
    • Abrupt reoxygenation following hypoxia reduces electrical coupling between endothelial cells of wild-type but not connexin40 null mice in oxidant- and PKA-dependent manner
    • Bolon ML, Ouellette Y, Li F, Tyml K. 2005. Abrupt reoxygenation following hypoxia reduces electrical coupling between endothelial cells of wild-type but not connexin40 null mice in oxidant- and PKA-dependent manner. FASEB J 19:1725-1727.
    • (2005) FASEB J , vol.19 , pp. 1725-1727
    • Bolon, M.L.1    Ouellette, Y.2    Li, F.3    Tyml, K.4
  • 8
    • 33847659645 scopus 로고    scopus 로고
    • Lipopolysaccharide reduces electrical coupling in microvascular endothelial cells by targeting connexin40 in a tyrosine-, ERK1/2-, PKA-, and PKC-dependent manner
    • Bolon ML, Kidder GM, Simon AM, Tyml K. 2007. Lipopolysaccharide reduces electrical coupling in microvascular endothelial cells by targeting connexin40 in a tyrosine-, ERK1/2-, PKA-, and PKC-dependent manner. J Cell Physiol 211:159-166.
    • (2007) J Cell Physiol , vol.211 , pp. 159-166
    • Bolon, M.L.1    Kidder, G.M.2    Simon, A.M.3    Tyml, K.4
  • 9
    • 0026051892 scopus 로고
    • Gram-negative sepsis. Background, clinical features, and intervention
    • Bone RC. 1991. Gram-negative sepsis. Background, clinical features, and intervention. Chest 100:802-808.
    • (1991) Chest , vol.100 , pp. 802-808
    • Bone, R.C.1
  • 10
    • 0028607201 scopus 로고
    • Role of protein kinase C in the regulation of gap junctional communication
    • Budunova IV, Mittelman LA, Miloszewska J. 1994. Role of protein kinase C in the regulation of gap junctional communication. Teratog Carcinog Mutagen 14:259-270.
    • (1994) Teratog Carcinog Mutagen , vol.14 , pp. 259-270
    • Budunova, I.V.1    Mittelman, L.A.2    Miloszewska, J.3
  • 11
    • 0035491305 scopus 로고    scopus 로고
    • Lung and liver injury following hepatic ischemia/reperfusion in the rat is increased by exogenous lipopolysaccharide which also increases hepatic TNF production in vivo and in vitro
    • Colletti LM, Green M. 2001. Lung and liver injury following hepatic ischemia/reperfusion in the rat is increased by exogenous lipopolysaccharide which also increases hepatic TNF production in vivo and in vitro. Shock 16:312-319.
    • (2001) Shock , vol.16 , pp. 312-319
    • Colletti, L.M.1    Green, M.2
  • 12
    • 0023142538 scopus 로고
    • Skeletal microcirculatory responses to hyperdynamic Escherichia coli sepsis in unanesthetized rats
    • Cryer HM, Garrison RN, Kaebnick HW, Harris PD, Flint LM. 1987. Skeletal microcirculatory responses to hyperdynamic Escherichia coli sepsis in unanesthetized rats. Arch Surg 122:86-92.
    • (1987) Arch Surg , vol.122 , pp. 86-92
    • Cryer, H.M.1    Garrison, R.N.2    Kaebnick, H.W.3    Harris, P.D.4    Flint, L.M.5
  • 14
    • 0034737654 scopus 로고    scopus 로고
    • de Wit C, Roos F, Bolz SS, Kirchhoff S, Kruger O, Willecke K, Pohl U. 2000. Impaired conduction of vasodilation along arterioles in connexin40-deficient mice. Circ Res 86:649-6S5.
    • de Wit C, Roos F, Bolz SS, Kirchhoff S, Kruger O, Willecke K, Pohl U. 2000. Impaired conduction of vasodilation along arterioles in connexin40-deficient mice. Circ Res 86:649-6S5.
  • 16
    • 0035007308 scopus 로고    scopus 로고
    • Electrical activation of endothelium evokes vasodilation and hyperpolarization along hamster feed arteries
    • Emerson GG, Segal SS. 2001. Electrical activation of endothelium evokes vasodilation and hyperpolarization along hamster feed arteries. Am J Physiol Heart Circ Physiol 280:H160-H167.
    • (2001) Am J Physiol Heart Circ Physiol , vol.280
    • Emerson, G.G.1    Segal, S.S.2
  • 18
    • 0033452740 scopus 로고    scopus 로고
    • bcl-X(S)-induced cell death in 3T3 cells does not require or induce caspase activation
    • Fridman JS, Benedict MA, Maybaum J. 1999. bcl-X(S)-induced cell death in 3T3 cells does not require or induce caspase activation. Cancer Res 59:5999-6004.
    • (1999) Cancer Res , vol.59 , pp. 5999-6004
    • Fridman, J.S.1    Benedict, M.A.2    Maybaum, J.3
  • 19
    • 1942470625 scopus 로고    scopus 로고
    • Contribution of connexins to the function of the vascular wall
    • Haefliger JA, Nicod P, Meda P. 2004. Contribution of connexins to the function of the vascular wall. Cardiovasc Res 62:345-356.
    • (2004) Cardiovasc Res , vol.62 , pp. 345-356
    • Haefliger, J.A.1    Nicod, P.2    Meda, P.3
  • 20
    • 0346850850 scopus 로고    scopus 로고
    • Oxidative stress reprograms lipopolysaccharide signaling via Src kinase-dependent pathway in RAW 264.7 macrophage cell line
    • Khadaroo RG, Kapus A, Powers KA, Cybulsky MI, Marshall JC, Rotstein OD. 2003. Oxidative stress reprograms lipopolysaccharide signaling via Src kinase-dependent pathway in RAW 264.7 macrophage cell line. J Biol Chem 278:47834-7841.
    • (2003) J Biol Chem , vol.278 , pp. 47834-47841
    • Khadaroo, R.G.1    Kapus, A.2    Powers, K.A.3    Cybulsky, M.I.4    Marshall, J.C.5    Rotstein, O.D.6
  • 22
    • 33644826498 scopus 로고    scopus 로고
    • Pathways and control of connexin oligomerization
    • Koval M. 2006. Pathways and control of connexin oligomerization. Trends Cell Biol 16:159-166.
    • (2006) Trends Cell Biol , vol.16 , pp. 159-166
    • Koval, M.1
  • 24
    • 0025569290 scopus 로고
    • Biochemical and immunochemical analysis of the arrangement of connexin43 in rat heart gap junction membranes
    • Laird DW, Revel JP. 1990. Biochemical and immunochemical analysis of the arrangement of connexin43 in rat heart gap junction membranes. J Cell Sci 97:109-117.
    • (1990) J Cell Sci , vol.97 , pp. 109-117
    • Laird, D.W.1    Revel, J.P.2
  • 25
    • 0028053865 scopus 로고
    • Microvascular perfusion is impaired in a rat model of normotensive sepsis
    • Lam C, Tyml K, Martin C, Sibbald W. 1994. Microvascular perfusion is impaired in a rat model of normotensive sepsis. J Clin Invest 94:2077-2083.
    • (1994) J Clin Invest , vol.94 , pp. 2077-2083
    • Lam, C.1    Tyml, K.2    Martin, C.3    Sibbald, W.4
  • 26
    • 0034671950 scopus 로고    scopus 로고
    • Regulation of gap junctions by phosphorylation of connexins
    • Lampe PD, Lau AF. 2000. Regulation of gap junctions by phosphorylation of connexins. Arch Biochem Biophys 384:205-215.
    • (2000) Arch Biochem Biophys , vol.384 , pp. 205-215
    • Lampe, P.D.1    Lau, A.F.2
  • 27
    • 0033843226 scopus 로고    scopus 로고
    • Endotoxin increases intercellular resistance in microvascular endothelial cells by a tyrosine kinase pathway
    • Lidington D, Ouellette Y, Tyml K. 2000. Endotoxin increases intercellular resistance in microvascular endothelial cells by a tyrosine kinase pathway. J Cell Physiol 185:117-125.
    • (2000) J Cell Physiol , vol.185 , pp. 117-125
    • Lidington, D.1    Ouellette, Y.2    Tyml, K.3
  • 28
    • 0038347425 scopus 로고    scopus 로고
    • Conducted vasoconstriction is reduced in a mouse model of sepsis
    • Lidington D, Ouellette Y, Li F, Tyml K. 2003. Conducted vasoconstriction is reduced in a mouse model of sepsis. J Vasc Res 40:149-158.
    • (2003) J Vasc Res , vol.40 , pp. 149-158
    • Lidington, D.1    Ouellette, Y.2    Li, F.3    Tyml, K.4
  • 29
    • 33847611016 scopus 로고    scopus 로고
    • Deletion of neuronal NOS prevents impaired vasodilation in septic mouse skeletal muscle
    • Lidington D, Li F, Tyml K. 2007. Deletion of neuronal NOS prevents impaired vasodilation in septic mouse skeletal muscle. Cardiovasc Res 74:151-158.
    • (2007) Cardiovasc Res , vol.74 , pp. 151-158
    • Lidington, D.1    Li, F.2    Tyml, K.3
  • 30
    • 0030972807 scopus 로고    scopus 로고
    • Transcriptional regulation by cyclic AMP
    • Montminy M. 1997. Transcriptional regulation by cyclic AMP. Annu Rev Biochem 66:807-822.
    • (1997) Annu Rev Biochem , vol.66 , pp. 807-822
    • Montminy, M.1
  • 31
    • 0027488960 scopus 로고
    • Early interactions of cancer cells with the microvasculature in mouse liver and muscle during hematogenous metastasis: Videomicroscopic analysis
    • Morris VL, MacDonald IC, Koop S, Schmidt EE, Chambers AF, Groom AC. 1993. Early interactions of cancer cells with the microvasculature in mouse liver and muscle during hematogenous metastasis: Videomicroscopic analysis. Clin Exp Metastasis 11:377-390.
    • (1993) Clin Exp Metastasis , vol.11 , pp. 377-390
    • Morris, V.L.1    MacDonald, I.C.2    Koop, S.3    Schmidt, E.E.4    Chambers, A.F.5    Groom, A.C.6
  • 33
    • 34249290789 scopus 로고    scopus 로고
    • Sepsis in the 21st century: Recent definitions and therapeutic advances
    • Nguyen HB, Smith D. 2007. Sepsis in the 21st century: Recent definitions and therapeutic advances. Am J Emerg Med 25:564-571.
    • (2007) Am J Emerg Med , vol.25 , pp. 564-571
    • Nguyen, H.B.1    Smith, D.2
  • 35
    • 33746601126 scopus 로고    scopus 로고
    • Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages
    • Powers KA, Szaszi K, Khadaroo RG, Tawadros PS, Marshall JC, Kapus A, Rotstein OD. 2006. Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages. J Exp Med 203:1951-1961.
    • (2006) J Exp Med , vol.203 , pp. 1951-1961
    • Powers, K.A.1    Szaszi, K.2    Khadaroo, R.G.3    Tawadros, P.S.4    Marshall, J.C.5    Kapus, A.6    Rotstein, O.D.7
  • 37
    • 8444252937 scopus 로고    scopus 로고
    • Protein kinase C spatially and temporally regulates gap junctional communication during human wound repair via phosphorylation of connexin43 on serine368
    • Richards TS, Dunn CA, Carter WG, Usui ML, Olerud JE, Lampe PD. 2004. Protein kinase C spatially and temporally regulates gap junctional communication during human wound repair via phosphorylation of connexin43 on serine368. J Cell Biol 167:555-562.
    • (2004) J Cell Biol , vol.167 , pp. 555-562
    • Richards, T.S.1    Dunn, C.A.2    Carter, W.G.3    Usui, M.L.4    Olerud, J.E.5    Lampe, P.D.6
  • 39
    • 20144374064 scopus 로고    scopus 로고
    • Hypoxia/reoxygenation reduces microvascular endothelial cell coupling by a tyrosine and MAP kinase dependent pathway
    • Rose K, Ouellette Y, Bolon M, Tyml K. 2005. Hypoxia/reoxygenation reduces microvascular endothelial cell coupling by a tyrosine and MAP kinase dependent pathway. J Cell Physiol 204:131-138.
    • (2005) J Cell Physiol , vol.204 , pp. 131-138
    • Rose, K.1    Ouellette, Y.2    Bolon, M.3    Tyml, K.4
  • 40
    • 0344196790 scopus 로고    scopus 로고
    • Expression of homocellular and heterocellular gap junctions in hamster arterioles and feed arteries
    • Sandow SL, Looft-Wilson R, Doran B, Grayson TH, Segal SS, Hill CE. 2003. Expression of homocellular and heterocellular gap junctions in hamster arterioles and feed arteries. Cardiovasc Res 60:643-653.
    • (2003) Cardiovasc Res , vol.60 , pp. 643-653
    • Sandow, S.L.1    Looft-Wilson, R.2    Doran, B.3    Grayson, T.H.4    Segal, S.S.5    Hill, C.E.6
  • 41
    • 33646092779 scopus 로고    scopus 로고
    • Cx37 and Cx43 localize to zona pellucida in mouse ovarian follicles
    • Simon AM, Chen H, Jackson CL. 2006. Cx37 and Cx43 localize to zona pellucida in mouse ovarian follicles. Cell Commun Adhes 13:61-77.
    • (2006) Cell Commun Adhes , vol.13 , pp. 61-77
    • Simon, A.M.1    Chen, H.2    Jackson, C.L.3
  • 42
    • 0038010467 scopus 로고    scopus 로고
    • Decreased intercellular dye-transfer and downregulation of non-ablated connexins in aortic endothelium deficient in connexin37 or connexin40
    • Simon AM, McWhorter AR. 2003. Decreased intercellular dye-transfer and downregulation of non-ablated connexins in aortic endothelium deficient in connexin37 or connexin40. J Cell Sci 116:2223-2236.
    • (2003) J Cell Sci , vol.116 , pp. 2223-2236
    • Simon, A.M.1    McWhorter, A.R.2
  • 43
    • 0031016934 scopus 로고    scopus 로고
    • Female infertility in mice lacking connexin 37
    • Simon AM, Goodenough DA, Li E, Paul DL. 1997. Female infertility in mice lacking connexin 37. Nature 385:525-529.
    • (1997) Nature , vol.385 , pp. 525-529
    • Simon, A.M.1    Goodenough, D.A.2    Li, E.3    Paul, D.L.4
  • 44
    • 0032567887 scopus 로고    scopus 로고
    • Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block
    • Simon AM, Goodenough DA, Paul DL. 1998. Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block. Curr Biol 8:295-298.
    • (1998) Curr Biol , vol.8 , pp. 295-298
    • Simon, A.M.1    Goodenough, D.A.2    Paul, D.L.3
  • 45
    • 5644239564 scopus 로고    scopus 로고
    • Decreased Intercellular communication and connexin expression in mouse aortic endothelium during lipopolysaccharide-induced inflammation
    • Simon AM, McWhorter AR, Chen H, Jackson CL, Ouellette Y. 2004. Decreased Intercellular communication and connexin expression in mouse aortic endothelium during lipopolysaccharide-induced inflammation. J Vasc Res 41:323-333.
    • (2004) J Vasc Res , vol.41 , pp. 323-333
    • Simon, A.M.1    McWhorter, A.R.2    Chen, H.3    Jackson, C.L.4    Ouellette, Y.5
  • 48
    • 0034822793 scopus 로고    scopus 로고
    • Lipopolysaccharide reduces intercellular coupling in vitro and arteriolar conducted response in vivo
    • Tyml K, Wang X, Lidington D, Ouellette Y. 2001. Lipopolysaccharide reduces intercellular coupling in vitro and arteriolar conducted response in vivo. Am J Physiol Heart Circ Physiol 281:H1397-H1406.
    • (2001) Am J Physiol Heart Circ Physiol , vol.281
    • Tyml, K.1    Wang, X.2    Lidington, D.3    Ouellette, Y.4
  • 51
    • 27144483559 scopus 로고    scopus 로고
    • Microvascular dysfunction as a cause of organ dysfunction in severe sepsis
    • Vincent JL, De Backer D. 2005. Microvascular dysfunction as a cause of organ dysfunction in severe sepsis. Crit Care 9:S9-S12.
    • (2005) Crit Care , vol.9
    • Vincent, J.L.1    De Backer, D.2
  • 52
    • 33750888832 scopus 로고    scopus 로고
    • Endothelial and smooth muscle cell conduction in arterioles controlling blood flow
    • Welsh DG, Segal SS. 1998. Endothelial and smooth muscle cell conduction in arterioles controlling blood flow. Am J Physiol 274:H178-H186.
    • (1998) Am J Physiol , vol.274
    • Welsh, D.G.1    Segal, S.S.2
  • 53
    • 0030154883 scopus 로고    scopus 로고
    • Ascorbate uptake by microvascular endothelial cells of rat skeletal muscle
    • Wilson JX, Dixon SJ, Yu J, Nees S, Tyml K. 1996. Ascorbate uptake by microvascular endothelial cells of rat skeletal muscle. Microcirculation 3:211-221.
    • (1996) Microcirculation , vol.3 , pp. 211-221
    • Wilson, J.X.1    Dixon, S.J.2    Yu, J.3    Nees, S.4    Tyml, K.5
  • 54
    • 0038311988 scopus 로고    scopus 로고
    • Ascorbate inhibits iNOS expression and preserves vasoconstrictor responsiveness in skeletal muscle of septic mice
    • Wu F, Wilson JX, Tyml K. 2003. Ascorbate inhibits iNOS expression and preserves vasoconstrictor responsiveness in skeletal muscle of septic mice. Am J Physiol Regul Integr Comp Physiol 285:R50-R56.
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.285
    • Wu, F.1    Wilson, J.X.2    Tyml, K.3


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