Design, synthesis, and bioactivity of putative tubulin ligands with adamantane core

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 18, 2008, Pages 5091-5094

  Zefirova, Olga N ^a,c   Nurieva, Evgeniya V ^a   Lemcke, Heiko ^b   Ivanov, Andrei A ^c   Shishov, Dmitrii V ^a   Weiss, Dieter G ^b   Kuznetsov, Sergei A ^b   Zefirov, Nikolay S ^a,c  

^a MOSCOW STATE UNIVERSITY   (Russian Federation)

^b UNIVERSITY OF ROSTOCK   (Germany)

^c INSTITUTE OF PHYSIOLOGICALLY ACTIVE COMPOUNDS   (Russian Federation)

Author keywords

Adamantane derivatives; Taxol; Taxol mimics; Taxoter; Tubulin ligands

Indexed keywords

ADAMANTANE DERIVATIVE; COLCHICINE; DOCETAXEL; LIGAND; N BENZOYLPHENYLISOSERYLOXYADAMANTANE; PACLITAXEL; PACLITAXEL DERIVATIVE; TAXOID; TUBULIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CARCINOMA CELL; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG BINDING; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG CARCINOMA; MICROTUBULE ASSEMBLY; POLYMERIZATION; PROTEIN AGGREGATION;

ADAMANTANE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BRAIN; CATTLE; COLCHICINE; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MICROTUBULES; MOLECULAR MIMICRY; PACLITAXEL; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN;

EID: 51349133964     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.07.116     Document Type: Article

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