Synthesis and antibacterial activity of a new series of 2,3,5,7-substituted-pyrido[2,3-d/]pyrimidin-4(3H)-one derivatives

Chemical and Pharmaceutical Bulletin

Volumn 56, Issue 9, 2008, Pages 1342-1348

  Bheemanapalli, Lakshmi Narayana ^a   Akkinepally, Raghuram Rao ^a   Pamulaparthy, Shanthan Rao ^b  

^a PANJAB UNIVERSITY   (India)

^b INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

1 ethyl 3 (3 dimethylaminopropyl) carbodiimide; Antibacterial activity; N substituted nicotinamide; Pyrido 2,3 pyrimidin 4(3H) one; Triethylorthopropionate

Indexed keywords

2 ETHYL 3 (4 IODOPHENYL) 5 METHYL 7 PHENYLPYRIDO[2,3 D]PYRIMIDIN 4(3H) ONE; 2 ETHYL 3 [4 (METHYLTHIO)PHENYL] 7 PHENYL 5 (TRIFLUOROMETHYL)PYRIDO[2,3 D]PYRIMIDIN 4(3H) ONE; 2 ETHYL 5 METHYL 7 PHENYL 3,2 TOLYLPYRIDO[2,3 D]PYRIMIDIN 4(3H) ONE; 2 ETHYL 7 PHENYL 5 (TRIFLUOROMETHYL) 3 [4 (TRIFLUOROMETHYL)PHENYL]PYRIDO[2,3 D]PYRIMIDIN 4(3H) ONE; 2,5 DIMETHYL 7 PHENYL 3,2 TOLYLPYRIDO[2,3 D]PYRIMIDIN 4(3H) ONE; 3 (3,4 DIMETHOXYPHENYL) 2 ETHYL 5 METHYL 7 PHENYLPYRIDO[2,3 D]PYRIMIDIN 4(3H) ONE; 3 (3,4 DIMETHOXYPHENYL) 2,5 DIMETHYL 7 PHENYLPYRIDO[2,3 D]PYRIMIDIN 4(3H) ONE; 3 (4 CHLOROPHENYL) 2 ETHYL 7 PHENYL 5 (TRIFLUOROMETHYL)PYRIDO[2,3 D]PYRIMIDIN 4(3H) ONE; 7 (4 CHLOROPHENYL) 2 ETHYL 3 (2 METHOXYPHENYL) 5 (TRIFLUOROMETHYL)PYRIDO[2,3 D]PYRIMIDIN 4(3H) ONE; 7 (4 CHLOROPHENYL) 2 ETHYL 3 (4 FLUOROPHENYL) 5 (TRIFLUOROMETHYL)PYRIDO[2,3 D]PYRIMIDIN 4(3H) ONE; 7 (4 CHLOROPHENYL) 2 ETHYL 3,4 TOLYL 5 (TRIFLUOROMETHYL)PYRIDO[2,3 D]PYRIMIDIN 4(3H) ONE; 7 (4 CHLOROPHENYL) 2 METHYL 3,4 TOLYL 5 (TRIFLUOROMETHYL)PYRIDO[2,3 D]PYRIMIDIN 4(3H) ONE; 7 (4 CHLOROPHENYL) 3 (2 METHOXYPHENYL) 2 METHYL 5 (TRIFLUOROMETHYL)PYRIDO[2,3 D]PYRIMIDIN 4(3H) ONE; 7 (4 CHLOROPHENYL) 3 (3,5 DIMETHYLPHENYL) 2 ETHYL 5 (TRIFLUOROMETHYL)PYRIDO[2,3 D]PYRIMIDIN 4(3H) ONE; 7 (4 CHLOROPHENYL) 3 (3,5 DIMETHYLPHENYL) 2 METHYL 5 (TRIFLUOROMETHYL)PYRIDO[2,3 D]PYRIMIDIN 4(3H) ONE; 7 (4 CHLOROPHENYL) 3 (4 FLUOROPHENYL) 2 METHYL 5 (TRIFLUOROMETHYL)PYRIDO[2,3 D]PYRIMIDIN 4(3H) ONE; AROMATIC AMINE; CIPROFLOXACIN; CYANAMIDE; ETHYL 3 (3 DIMETHYLAMINOPROPYL)CARBODIIMIDE; NICOTINAMIDE DERIVATIVE; NICOTINIC ACID DERIVATIVE; PYRIDO[2,3 D]PYRIMIDIN 4(3H)ONE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CHEMICAL REACTION; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN;

ANTI-BACTERIAL AGENTS; BACTERIA; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MICROBIAL SENSITIVITY TESTS; PYRIMIDINONES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, INFRARED; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 51349130182     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.56.1342     Document Type: Article

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