Syntheses and evaluation of pyrido[2,3-d]pyrimidine-2,4-diones as PDE 4 inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 5, 2001, Pages 611-614

  Nam, Ghilsoo ^a   Yoon, Cheol Min ^b   Kim, Euikyung ^c   Rhee, Chung K ^c   Kim, Joong Hyup ^a   Shin, Jung Hyu ^d   Kim, Sung Hoon ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Korea University   (South Korea)

^c CJ Corporation   (South Korea)

^d Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CILOMILAST; CP 77059; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; PYRIDINE DERIVATIVE; PYRIDO[2,3 D]PYRIMIDINE 2,4 DIONE DERIVATIVE; ROLIPRAM; RS 25344; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BINDING; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; NONHUMAN; RAT;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; BIOLOGICAL ASSAY; HUMANS; MOLECULAR STRUCTURE; PHOSPHODIESTERASE INHIBITORS; PYRIMIDINES; QUINAZOLINES; RATS; ROLIPRAM;

EID: 0035848414     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00681-8     Document Type: Article

References (25)

1. Reviews