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Volumn 34, Issue 10, 2008, Pages 1191-1197

Mechanisms of N-acetyl Cysteine-mediated Protection From 2-Hydroxyethyl Methacrylate-induced Apoptosis

Author keywords

2 hydroxyethyl methacrylate; caspases; mitochondria; N acetyl cysteine

Indexed keywords

2 HYDROXYETHYL METHACRYLATE; ACETYLCYSTEINE; BIOMEDICAL AND DENTAL MATERIALS; CASPASE; CASPASE 3; ENZYME INHIBITOR; METHACRYLIC ACID DERIVATIVE; PROTECTIVE AGENT; SCAVENGER;

EID: 51349116390     PISSN: 00992399     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joen.2008.06.011     Document Type: Article
Times cited : (25)

References (40)
  • 1
    • 0037433792 scopus 로고    scopus 로고
    • In vitro uptake and release studies of ocular pharmaceutical agents by silicon-containing and p-hema hydrogel contact lens materials
    • Karlgard C.C., Wong N.S., Jones L.W., and Moresoli C. In vitro uptake and release studies of ocular pharmaceutical agents by silicon-containing and p-hema hydrogel contact lens materials. Int J Pharm 257 (2003) 141-151
    • (2003) Int J Pharm , vol.257 , pp. 141-151
    • Karlgard, C.C.1    Wong, N.S.2    Jones, L.W.3    Moresoli, C.4
  • 2
    • 17644369636 scopus 로고    scopus 로고
    • Salivary bisphenol-a levels detected by elisa after restoration with composite resin
    • Sasaki N., Okuda K., Kato T., et al. Salivary bisphenol-a levels detected by elisa after restoration with composite resin. J Mater Sci Mater Med 16 (2005) 297-300
    • (2005) J Mater Sci Mater Med , vol.16 , pp. 297-300
    • Sasaki, N.1    Okuda, K.2    Kato, T.3
  • 3
    • 34247610806 scopus 로고    scopus 로고
    • In vitro cytotoxicity of dental composites based on new and traditional polymerization chemistries
    • Brackett M.G., Bouillaguet S., Lockwood P.E., et al. In vitro cytotoxicity of dental composites based on new and traditional polymerization chemistries. J Biomed Mater Res B Appl Biomater 81 (2007) 397-402
    • (2007) J Biomed Mater Res B Appl Biomater , vol.81 , pp. 397-402
    • Brackett, M.G.1    Bouillaguet, S.2    Lockwood, P.E.3
  • 4
    • 51349099030 scopus 로고    scopus 로고
    • Effects of monomers eluted from dental resin restoratives on osteoblast-like cells
    • [Epub ahead of print]
    • Imazato S., Horikawa D., Nishida M., and Ebisu S. Effects of monomers eluted from dental resin restoratives on osteoblast-like cells. J Biomed Mater Res B Appl Biomater (2008) [Epub ahead of print]
    • (2008) J Biomed Mater Res B Appl Biomater
    • Imazato, S.1    Horikawa, D.2    Nishida, M.3    Ebisu, S.4
  • 5
    • 33748579626 scopus 로고    scopus 로고
    • Initial in vitro biological response to contemporary endodontic sealers
    • Bouillaguet S., Wataha J.C., Tay F.R., Brackett M.G., and Lockwood P.E. Initial in vitro biological response to contemporary endodontic sealers. J Endod 32 (2006) 989-992
    • (2006) J Endod , vol.32 , pp. 989-992
    • Bouillaguet, S.1    Wataha, J.C.2    Tay, F.R.3    Brackett, M.G.4    Lockwood, P.E.5
  • 6
    • 2442650115 scopus 로고    scopus 로고
    • An evaluation of microbial leakage in roots filled with a thermoplastic synthetic polymer-based root canal filling material (Resilon)
    • Shipper G., Orstavik D., Teixeira F.B., and Trope M. An evaluation of microbial leakage in roots filled with a thermoplastic synthetic polymer-based root canal filling material (Resilon). J Endod 30 (2004) 342-347
    • (2004) J Endod , vol.30 , pp. 342-347
    • Shipper, G.1    Orstavik, D.2    Teixeira, F.B.3    Trope, M.4
  • 7
    • 0037339672 scopus 로고    scopus 로고
    • Leg ulcers associated with cryoglobulinemia: clinical study of 15 patients and response to treatment
    • Auzerie V., Chiali A., Bussel A., et al. Leg ulcers associated with cryoglobulinemia: clinical study of 15 patients and response to treatment. Arch Dermatol 139 (2003) 391-393
    • (2003) Arch Dermatol , vol.139 , pp. 391-393
    • Auzerie, V.1    Chiali, A.2    Bussel, A.3
  • 8
    • 0036945455 scopus 로고    scopus 로고
    • Occupational contact urticaria from diglycidyl ether of bisphenol a epoxy resin
    • Kanerva L., Pelttari M., Jolanki R., Alanko K., Estlander T., and Suhonen R. Occupational contact urticaria from diglycidyl ether of bisphenol a epoxy resin. Allergy 57 (2002) 1205-1207
    • (2002) Allergy , vol.57 , pp. 1205-1207
    • Kanerva, L.1    Pelttari, M.2    Jolanki, R.3    Alanko, K.4    Estlander, T.5    Suhonen, R.6
  • 9
    • 0029179638 scopus 로고
    • Effect of hydrostatic pressure on the diffusion of monomers through dentin in vitro
    • Gerzina T.M., and Hume W.R. Effect of hydrostatic pressure on the diffusion of monomers through dentin in vitro. J Dent Res 74 (1995) 369-373
    • (1995) J Dent Res , vol.74 , pp. 369-373
    • Gerzina, T.M.1    Hume, W.R.2
  • 10
    • 0029688759 scopus 로고    scopus 로고
    • Diffusion of monomers from bonding resin-resin composite combinations through dentine in vitro
    • Gerzina T.M., and Hume W.R. Diffusion of monomers from bonding resin-resin composite combinations through dentine in vitro. J Dent 24 (1996) 125-128
    • (1996) J Dent , vol.24 , pp. 125-128
    • Gerzina, T.M.1    Hume, W.R.2
  • 11
    • 0031063088 scopus 로고    scopus 로고
    • Diffusion of resin monomers through human carious dentin in vitro
    • Hamid A., and Hume W.R. Diffusion of resin monomers through human carious dentin in vitro. Endod Dent Traumatol 13 (1997) 1-5
    • (1997) Endod Dent Traumatol , vol.13 , pp. 1-5
    • Hamid, A.1    Hume, W.R.2
  • 12
    • 0030641459 scopus 로고    scopus 로고
    • The effect of dentine thickness on diffusion of resin monomers in vitro
    • Hamid A., and Hume W.R. The effect of dentine thickness on diffusion of resin monomers in vitro. J Oral Rehabil 24 (1997) 20-25
    • (1997) J Oral Rehabil , vol.24 , pp. 20-25
    • Hamid, A.1    Hume, W.R.2
  • 13
    • 35148894597 scopus 로고    scopus 로고
    • N-acetylcysteine protects dental pulp stromal cells from hema-induced apoptosis by inducing differentiation of the cells
    • Paranjpe A., Cacalano N.A., Hume W.R., and Jewett A. N-acetylcysteine protects dental pulp stromal cells from hema-induced apoptosis by inducing differentiation of the cells. Free Radic Biol Med 43 (2007) 1394-1408
    • (2007) Free Radic Biol Med , vol.43 , pp. 1394-1408
    • Paranjpe, A.1    Cacalano, N.A.2    Hume, W.R.3    Jewett, A.4
  • 14
    • 38349058113 scopus 로고    scopus 로고
    • An in vitro evaluation of the growth of human periodontal ligament fibroblasts after exposure to a methacrylate-based endodontic sealer
    • Heitman E.P., Joyce A.P., McPherson III J.C., Roberts S., and Chuang A. An in vitro evaluation of the growth of human periodontal ligament fibroblasts after exposure to a methacrylate-based endodontic sealer. J Endod 34 (2008) 186-189
    • (2008) J Endod , vol.34 , pp. 186-189
    • Heitman, E.P.1    Joyce, A.P.2    McPherson III, J.C.3    Roberts, S.4    Chuang, A.5
  • 15
    • 15544383039 scopus 로고    scopus 로고
    • Resin monomer 2-hydroxyethyl methacrylate (hema) is a potent inducer of apoptotic cell death in human and mouse cells
    • Paranjpe A., Bordador L.C., Wang M.Y., Hume W.R., and Jewett A. Resin monomer 2-hydroxyethyl methacrylate (hema) is a potent inducer of apoptotic cell death in human and mouse cells. J Dent Res 84 (2005) 172-177
    • (2005) J Dent Res , vol.84 , pp. 172-177
    • Paranjpe, A.1    Bordador, L.C.2    Wang, M.Y.3    Hume, W.R.4    Jewett, A.5
  • 17
    • 0033529634 scopus 로고    scopus 로고
    • Caspase activation involves the formation of the aposome, a large (approximately 700 kda) caspase-activating complex
    • Cain K., Brown D.G., Langlais C., and Cohen G.M. Caspase activation involves the formation of the aposome, a large (approximately 700 kda) caspase-activating complex. J Biol Chem 274 (1999) 22686-22692
    • (1999) J Biol Chem , vol.274 , pp. 22686-22692
    • Cain, K.1    Brown, D.G.2    Langlais, C.3    Cohen, G.M.4
  • 18
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green D.R., and Reed J.C. Mitochondria and apoptosis. Science 281 (1998) 1309-1312
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 19
    • 2942519187 scopus 로고    scopus 로고
    • N-acetyl cysteine regulates TNF-alpha-inhibited differentiation in ros 17/2.8 osteoblasts
    • Chae H.J., Chae S.W., and Kim H.R. N-acetyl cysteine regulates TNF-alpha-inhibited differentiation in ros 17/2.8 osteoblasts. Immunopharmacol Immunotoxicol 26 (2004) 203-213
    • (2004) Immunopharmacol Immunotoxicol , vol.26 , pp. 203-213
    • Chae, H.J.1    Chae, S.W.2    Kim, H.R.3
  • 20
    • 34247160064 scopus 로고    scopus 로고
    • Inhibition of TEGDMA and HEMA-induced genotoxicity and cell cycle arrest by N-acetylcysteine
    • Schweikl H., Hartmann A., Hiller K.A., et al. Inhibition of TEGDMA and HEMA-induced genotoxicity and cell cycle arrest by N-acetylcysteine. Dent Mater 23 (2007) 688-695
    • (2007) Dent Mater , vol.23 , pp. 688-695
    • Schweikl, H.1    Hartmann, A.2    Hiller, K.A.3
  • 22
    • 28744458359 scopus 로고    scopus 로고
    • Effect of n-acetyl-l-cysteine on ROS production and cell death caused by hema in human primary gingival fibroblasts
    • Spagnuolo G., D'Anto V., Cosentino C., Schmalz G., Schweikl H., and Rengo S. Effect of n-acetyl-l-cysteine on ROS production and cell death caused by hema in human primary gingival fibroblasts. Biomaterials 27 (2006) 1803-1809
    • (2006) Biomaterials , vol.27 , pp. 1803-1809
    • Spagnuolo, G.1    D'Anto, V.2    Cosentino, C.3    Schmalz, G.4    Schweikl, H.5    Rengo, S.6
  • 23
    • 4444355381 scopus 로고    scopus 로고
    • Stimulation of glutathione depletion, ROS production and cell cycle arrest of dental pulp cells and gingival epithelial cells by HEMA
    • Chang H.H., Guo M.K., Kasten F.H., et al. Stimulation of glutathione depletion, ROS production and cell cycle arrest of dental pulp cells and gingival epithelial cells by HEMA. Biomaterials 26 (2005) 745-753
    • (2005) Biomaterials , vol.26 , pp. 745-753
    • Chang, H.H.1    Guo, M.K.2    Kasten, F.H.3
  • 24
    • 0034724653 scopus 로고    scopus 로고
    • N-acetylcysteine suppresses TNF-induced NF-kappaB activation through inhibition of IkappaB kinases
    • Oka S., Kamata H., Kamata K., Yagisawa H., and Hirata H. N-acetylcysteine suppresses TNF-induced NF-kappaB activation through inhibition of IkappaB kinases. FEBS Lett 472 (2000) 196-202
    • (2000) FEBS Lett , vol.472 , pp. 196-202
    • Oka, S.1    Kamata, H.2    Kamata, K.3    Yagisawa, H.4    Hirata, H.5
  • 25
    • 33750045758 scopus 로고    scopus 로고
    • Genetic and cellular toxicology of dental resin monomers
    • Schweikl H., Spagnuolo G., and Schmalz G. Genetic and cellular toxicology of dental resin monomers. J Dent Res 85 (2006) 870-877
    • (2006) J Dent Res , vol.85 , pp. 870-877
    • Schweikl, H.1    Spagnuolo, G.2    Schmalz, G.3
  • 26
    • 26844509194 scopus 로고    scopus 로고
    • Global gene expression analysis in time series following n-acetyl l-cysteine induced epithelial differentiation of human normal and cancer cells in vitro
    • Gustafsson A.C., Kupershmidt I., Edlundh-Rose E., et al. Global gene expression analysis in time series following n-acetyl l-cysteine induced epithelial differentiation of human normal and cancer cells in vitro. BMC Cancer 5 (2005) 75
    • (2005) BMC Cancer , vol.5 , pp. 75
    • Gustafsson, A.C.1    Kupershmidt, I.2    Edlundh-Rose, E.3
  • 27
    • 26844471893 scopus 로고    scopus 로고
    • Differentiation of normal and cancer cells induced by sulfhydryl reduction: biochemical and molecular mechanisms
    • Parasassi T., Brunelli R., Bracci-Laudiero L., et al. Differentiation of normal and cancer cells induced by sulfhydryl reduction: biochemical and molecular mechanisms. Cell Death Differ 12 (2005) 1285-1296
    • (2005) Cell Death Differ , vol.12 , pp. 1285-1296
    • Parasassi, T.1    Brunelli, R.2    Bracci-Laudiero, L.3
  • 28
    • 45849145075 scopus 로고    scopus 로고
    • N-acetyl cysteine protects pulp cells from resin toxins in vivo
    • Paranjpe A., Sung E.C., Cacalano N.A., Hume W.R., and Jewett A. N-acetyl cysteine protects pulp cells from resin toxins in vivo. J Dent Res 87 (2008) 537-541
    • (2008) J Dent Res , vol.87 , pp. 537-541
    • Paranjpe, A.1    Sung, E.C.2    Cacalano, N.A.3    Hume, W.R.4    Jewett, A.5
  • 29
    • 0036103384 scopus 로고    scopus 로고
    • Dentist's occupational asthma, rhinoconjunctivitis, and allergic contact dermatitis from methacrylates
    • Lindstrom M., Alanko K., Keskinen H., and Kanerva L. Dentist's occupational asthma, rhinoconjunctivitis, and allergic contact dermatitis from methacrylates. Allergy 57 (2002) 543-545
    • (2002) Allergy , vol.57 , pp. 543-545
    • Lindstrom, M.1    Alanko, K.2    Keskinen, H.3    Kanerva, L.4
  • 30
    • 0029793030 scopus 로고    scopus 로고
    • Bioavailability of components of resin-based materials which are applied to teeth
    • Hume W.R., and Gerzia T.M. Bioavailability of components of resin-based materials which are applied to teeth. Crit Rev Oral Biol Med 7 (1996) 172-179
    • (1996) Crit Rev Oral Biol Med , vol.7 , pp. 172-179
    • Hume, W.R.1    Gerzia, T.M.2
  • 31
    • 0033228259 scopus 로고    scopus 로고
    • Human pulp response after an adhesive system application in deep cavities
    • Hebling J., Giro E.M., and Costa C.A. Human pulp response after an adhesive system application in deep cavities. J Dent 27 (1999) 557-564
    • (1999) J Dent , vol.27 , pp. 557-564
    • Hebling, J.1    Giro, E.M.2    Costa, C.A.3
  • 32
    • 0029950290 scopus 로고    scopus 로고
    • Bcl-2 inhibits the mitochondrial release of an apoptogenic protease
    • Susin S.A., Zamzami N., Castedo M., et al. Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J Exp Med 184 (1996) 1331-1341
    • (1996) J Exp Med , vol.184 , pp. 1331-1341
    • Susin, S.A.1    Zamzami, N.2    Castedo, M.3
  • 33
    • 0032567877 scopus 로고    scopus 로고
    • The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of bcl-2 by enforcing mitochondrial permeability transition
    • Zamzami N., Marzo I., Susin S.A., et al. The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of bcl-2 by enforcing mitochondrial permeability transition. Oncogene 16 (1998) 1055-1063
    • (1998) Oncogene , vol.16 , pp. 1055-1063
    • Zamzami, N.1    Marzo, I.2    Susin, S.A.3
  • 34
    • 0742323605 scopus 로고    scopus 로고
    • Antioxidative vitamins decrease cytotoxicity of HEMA and TEGDMA in cultured cell lines
    • Walther U.I., Siagian I.I., Walther S.C., Reichl F.X., and Hickel R. Antioxidative vitamins decrease cytotoxicity of HEMA and TEGDMA in cultured cell lines. Arch Oral Biol 49 (2004) 125-131
    • (2004) Arch Oral Biol , vol.49 , pp. 125-131
    • Walther, U.I.1    Siagian, I.I.2    Walther, S.C.3    Reichl, F.X.4    Hickel, R.5
  • 36
    • 33845414175 scopus 로고    scopus 로고
    • Apoptosis induced by the monomers hema and TEGDMA involves formation of ROS and differential activation of the map-kinases p38, jnk and erk
    • Samuelsen J.T., Dahl J.E., Karlsson S., Morisbak E., and Becher R. Apoptosis induced by the monomers hema and TEGDMA involves formation of ROS and differential activation of the map-kinases p38, jnk and erk. Dent Mater 23 (2007) 34-39
    • (2007) Dent Mater , vol.23 , pp. 34-39
    • Samuelsen, J.T.1    Dahl, J.E.2    Karlsson, S.3    Morisbak, E.4    Becher, R.5
  • 37
    • 16544376816 scopus 로고    scopus 로고
    • NF-kappaB protection against apoptosis induced by hema
    • Spagnuolo G., Mauro C., Leonardi A., et al. NF-kappaB protection against apoptosis induced by hema. J Dent Res 83 (2004) 837-842
    • (2004) J Dent Res , vol.83 , pp. 837-842
    • Spagnuolo, G.1    Mauro, C.2    Leonardi, A.3
  • 38
    • 43549108541 scopus 로고    scopus 로고
    • Effect of 2-hydroxyethyl methacrylate on human pulp cell survival pathways ERK and AKT
    • Spagnuolo G., D'Anto V., Valletta R., et al. Effect of 2-hydroxyethyl methacrylate on human pulp cell survival pathways ERK and AKT. J Endod 34 (2008) 684-688
    • (2008) J Endod , vol.34 , pp. 684-688
    • Spagnuolo, G.1    D'Anto, V.2    Valletta, R.3
  • 39
    • 33750508107 scopus 로고    scopus 로고
    • Involvement of oxidative stress in mutagenicity and apoptosis caused by dental resin monomers in cell cultures
    • Lee D.H., Lim B.S., Lee Y.K., Ahn S.J., and Yang H.C. Involvement of oxidative stress in mutagenicity and apoptosis caused by dental resin monomers in cell cultures. Dent Mater 22 (2006) 1086-1092
    • (2006) Dent Mater , vol.22 , pp. 1086-1092
    • Lee, D.H.1    Lim, B.S.2    Lee, Y.K.3    Ahn, S.J.4    Yang, H.C.5
  • 40
    • 33750484015 scopus 로고    scopus 로고
    • Antioxidant and anti-inflammatory efficacy of NAC in the treatment of COPD: discordant in vitro and in vivo dose-effects: a review
    • Sadowska A.M., Manuel Y.K.B., and De Backer W.A. Antioxidant and anti-inflammatory efficacy of NAC in the treatment of COPD: discordant in vitro and in vivo dose-effects: a review. Pulm Pharmacol Ther 20 (2007) 9-22
    • (2007) Pulm Pharmacol Ther , vol.20 , pp. 9-22
    • Sadowska, A.M.1    Manuel, Y.K.B.2    De Backer, W.A.3


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