Activated B cells modified by electroporation of multiple mRNAs encoding immune stimulatory molecules are comparable to mature dendritic cells in inducing in vitro antigen-specific T-cell responses

Immunology

Volumn 125, Issue 2, 2008, Pages 229-240

  Lee, Jaewoo ^a,b   Dollins, Claudia M ^a,b   Boczkowski, David ^a,b   Sullenger, Bruce A ^a,b   Nair, Smita ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

B cell; Costimulatory molecule; Cytokine; Dendritic cell; RNA modification

Indexed keywords

CD137 LIGAND; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 2; MESSENGER RNA; OX40 LIGAND; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE ACTIVATION; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL MATURATION; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DOWN REGULATION; ELECTROPORATION; IMMUNE RESPONSE; IMMUNOREGULATION; IMMUNOSTIMULATION; IMMUNOTHERAPY; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE;

4-1BB LIGAND; ANIMALS; ANTIGENS, CD40; B-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CYTOKINES; CYTOTOXICITY, IMMUNOLOGIC; DENDRITIC CELLS; ELECTROPORATION; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COOPERATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RNA, MESSENGER; SPLEEN; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTORS;

EID: 51249118234     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2008.02833.x     Document Type: Article

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