Exclusive KRAS mutation in microsatellite-unstable human colorectal carcinomas with sequence alterations in the DNA mismatch repair gene, MLH1

Gene

Volumn 423, Issue 2, 2008, Pages 188-193

  Zhao, Yan ^a,b   Miyashita, Kaname ^a   Ando, Takayuki ^c   Kakeji, Yoshihiro ^b   Yamanaka, Takeharu ^a   Taguchi, Kenichi ^a   Ushijima, Toshikazu ^c   Oda, Shinya ^a   Maehara, Yoshihiko ^b  

^a NATIONAL KYUSHU CANCER CENTER   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

Base substitutions; DNA mismatch repair; Microsatellite instability (MSI); Mutator phenotype; Replication errors

Indexed keywords

MICROSATELLITE DNA;

ADOLESCENT; ADULT; AGED; ARTICLE; COLORECTAL CARCINOMA; CONTROLLED STUDY; FEMALE; GENE MUTATION; GENE SEQUENCE; HUMAN; MALE; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; ONCOGENE K RAS; PHENOTYPE; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BASE SEQUENCE; CODON; COLORECTAL NEOPLASMS; DNA MISMATCH REPAIR; FEMALE; HUMANS; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MUTATION; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; RAS PROTEINS;

EID: 51249089446     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2008.07.014     Document Type: Article

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