-
1
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971; 285: 1182-1186.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
2
-
-
20144382426
-
-
Marx J. Cancer. Encouraging results for second-generation anti-angiogenesis drugs. Science 2005; 308: 1248-1249.
-
Marx J. Cancer. Encouraging results for second-generation anti-angiogenesis drugs. Science 2005; 308: 1248-1249.
-
-
-
-
3
-
-
35349027402
-
Antimyeloma effects of resveratrol through inhibition of angiogenesis
-
Hu Y, Sun CY, Huang J, Hong L, Zhang L, Chu ZB. Antimyeloma effects of resveratrol through inhibition of angiogenesis. Chin Med J 2007; 120: 1672-1677.
-
(2007)
Chin Med J
, vol.120
, pp. 1672-1677
-
-
Hu, Y.1
Sun, C.Y.2
Huang, J.3
Hong, L.4
Zhang, L.5
Chu, Z.B.6
-
4
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastaticcolorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hansworth J, Heim W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastaticcolorectal cancer. N Engl J Med 2004; 350: 2335-2342
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hansworth, J.5
Heim, W.6
-
5
-
-
32944463899
-
Angiogenesis
-
Folkman J. Angiogenesis. Annu Rev Med 2006; 57: 1-18.
-
(2006)
Annu Rev Med
, vol.57
, pp. 1-18
-
-
Folkman, J.1
-
6
-
-
0037967272
-
Tumorigenesis and the angiogenic switch
-
Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat Rev Cancer 2003; 3: 401-410.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 401-410
-
-
Bergers, G.1
Benjamin, L.E.2
-
7
-
-
33750630119
-
HIF-2alpha promotes an aggressive phenotype
-
Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma
-
Holmquist-Mengelbier L, Fredlund E, Löfstedt T, Noguera R, Navarro S, Nilsson H, et al, Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype. Cancer Cell 2006; 10: 413-423.
-
(2006)
Cancer Cell
, vol.10
, pp. 413-423
-
-
Holmquist-Mengelbier, L.1
Fredlund, E.2
Löfstedt, T.3
Noguera, R.4
Navarro, S.5
Nilsson, H.6
-
8
-
-
42449130564
-
-
Shin DH, Chun YS, Lee DS, Huang LE, Park JW. Bortezomib inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated repression of hypoxia-inducible factor-1. Blood 2008 Jan 3, Epub ahead of print.
-
Shin DH, Chun YS, Lee DS, Huang LE, Park JW. Bortezomib inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated repression of hypoxia-inducible factor-1. Blood 2008 Jan 3, Epub ahead of print.
-
-
-
-
9
-
-
0036359548
-
Hypoxia-a key regulatory factor in tumour growth
-
Harris AL. Hypoxia-a key regulatory factor in tumour growth. Nat Rev Cancer 2002; 2: 38-47.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
10
-
-
33747873394
-
Hypoxia inducible factors 1alpha and 2alpha are associated with VEGF expression and angiogenesis in gallbladder carcinomas
-
Giatromanolaki A, Sivridis E, Simopoulos C, Polychronidis A, Gatter KC, Harris AL, et al. Hypoxia inducible factors 1alpha and 2alpha are associated with VEGF expression and angiogenesis in gallbladder carcinomas. J Surg Oncol 2006; 94: 242-247.
-
(2006)
J Surg Oncol
, vol.94
, pp. 242-247
-
-
Giatromanolaki, A.1
Sivridis, E.2
Simopoulos, C.3
Polychronidis, A.4
Gatter, K.C.5
Harris, A.L.6
-
11
-
-
33746932442
-
Angiopoietin 2 expression in invasive ductal carcinoma of the breast: Its relationship to the VEGF expression and microvessel density
-
Tsutsui S, Inoue H, Yasuda K, Suzuki K, Takeuchi H, Nishizaki T, et al. Angiopoietin 2 expression in invasive ductal carcinoma of the breast: its relationship to the VEGF expression and microvessel density. Breast Cancer Res Treat 2006; 98:261-266.
-
(2006)
Breast Cancer Res Treat
, vol.98
, pp. 261-266
-
-
Tsutsui, S.1
Inoue, H.2
Yasuda, K.3
Suzuki, K.4
Takeuchi, H.5
Nishizaki, T.6
-
12
-
-
33645737997
-
Angiogenesis in cholangiocellular carcinoma: Expression of vascular endothelial growth factor, angiopoietin-1/2, thrombospondin-1 and clinicopathological significance
-
Tang D, Nagano H, Yamamoto H, Wada H, Nakamura M, Kondo M, et al. Angiogenesis in cholangiocellular carcinoma: expression of vascular endothelial growth factor, angiopoietin-1/2, thrombospondin-1 and clinicopathological significance. Oncol Rep 2006; 15: 525-532.
-
(2006)
Oncol Rep
, vol.15
, pp. 525-532
-
-
Tang, D.1
Nagano, H.2
Yamamoto, H.3
Wada, H.4
Nakamura, M.5
Kondo, M.6
-
13
-
-
33845325814
-
A mechanism-based combination therapy reduces local tumor growth and metastasis in an orthotopic model of prostate cancer
-
Kosharskyy B, Solban N, Chang SK, Rizvi I, Chang Y, Hasan T. A mechanism-based combination therapy reduces local tumor growth and metastasis in an orthotopic model of prostate cancer. Cancer Res 2006; 66: 10953-10958.
-
(2006)
Cancer Res
, vol.66
, pp. 10953-10958
-
-
Kosharskyy, B.1
Solban, N.2
Chang, S.K.3
Rizvi, I.4
Chang, Y.5
Hasan, T.6
-
14
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan, D. Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996; 86:353-364.
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
15
-
-
2542520723
-
Two steps forward in the treatment of colorectal cancer
-
Mayer RJ. Two steps forward in the treatment of colorectal cancer. N Engl J Med 2004; 350:2406-2408.
-
(2004)
N Engl J Med
, vol.350
, pp. 2406-2408
-
-
Mayer, R.J.1
-
16
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996; 86: 353-364.
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
17
-
-
33645772227
-
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain
-
Sun L, Hui AM, Su Q, Vortmeyer A, Kotliarov Y, Pastorino S, et al. Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain. Cancer Cell 2006; 9: 287-300.
-
(2006)
Cancer Cell
, vol.9
, pp. 287-300
-
-
Sun, L.1
Hui, A.M.2
Su, Q.3
Vortmeyer, A.4
Kotliarov, Y.5
Pastorino, S.6
-
18
-
-
30744432102
-
Aktl regulates pathological angiogenesis, vascular maturation and permeability in vivo
-
Chen J, Somanath PR, Razorenova O, Chen WS, Hay N, Bornstein P, et al. Aktl regulates pathological angiogenesis, vascular maturation and permeability in vivo. Nat Med 2005, 11: 1188-1196.
-
(2005)
Nat Med
, vol.11
, pp. 1188-1196
-
-
Chen, J.1
Somanath, P.R.2
Razorenova, O.3
Chen, W.S.4
Hay, N.5
Bornstein, P.6
-
19
-
-
0036152857
-
Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins
-
Reynolds LE, Wyder L, Lively JC, Taverna D, Robinson SD, Huang X, et al. Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins. Nat Med 2002, 8: 27-34.
-
(2002)
Nat Med
, vol.8
, pp. 27-34
-
-
Reynolds, L.E.1
Wyder, L.2
Lively, J.C.3
Taverna, D.4
Robinson, S.D.5
Huang, X.6
-
20
-
-
0033580889
-
Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF
-
Holash J, Maisonpierre PC, Compton D, Boland P, Alexander CR, Zagzag D, et al. Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science 1999; 284: 1994-1998.
-
(1999)
Science
, vol.284
, pp. 1994-1998
-
-
Holash, J.1
Maisonpierre, P.C.2
Compton, D.3
Boland, P.4
Alexander, C.R.5
Zagzag, D.6
-
21
-
-
33746800144
-
Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin
-
Phung TL, Ziv K, Dabydeen D, Eyiah-Mensah G, Riveros M, Perruzzi C, et al. Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin. Cancer Cell 2006; 10: 159-170.
-
(2006)
Cancer Cell
, vol.10
, pp. 159-170
-
-
Phung, T.L.1
Ziv, K.2
Dabydeen, D.3
Eyiah-Mensah, G.4
Riveros, M.5
Perruzzi, C.6
-
22
-
-
14844325322
-
Tuniour parameters affected by combretastatin A-4 phosphate therapy in a human colorectal xenograft model in nude mice
-
El-Fmir E, Boxer GM, Petrie IA, Boden RW, Dearling JL, Regent RH, et al. Tuniour parameters affected by combretastatin A-4 phosphate therapy in a human colorectal xenograft model in nude mice. Eur J Cancer 2005, 41: 799-806.
-
(2005)
Eur J Cancer
, vol.41
, pp. 799-806
-
-
El-Fmir, E.1
Boxer, G.M.2
Petrie, I.A.3
Boden, R.W.4
Dearling, J.L.5
Regent, R.H.6
-
24
-
-
1642472018
-
Anti-angiogenic therapy and tumor progression
-
Blagosklomy MV. Anti-angiogenic therapy and tumor progression. Cancer Cell 2004; 5: 13-17.
-
(2004)
Cancer Cell
, vol.5
, pp. 13-17
-
-
Blagosklomy, M.V.1
-
25
-
-
0033822622
-
Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption
-
Rubenstein JL, Kim J, Ozawa T, Zhang M, Westphal M, Deen DF, et al. Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption. Neoplasia 2000; 2: 306-314.
-
(2000)
Neoplasia
, vol.2
, pp. 306-314
-
-
Rubenstein, J.L.1
Kim, J.2
Ozawa, T.3
Zhang, M.4
Westphal, M.5
Deen, D.F.6
-
26
-
-
0029851451
-
Time distribution of the recurrence risk for breast cancer patients undergoing mastectomy: Further support about the concept of tumor dormancy
-
Demicheli R, Abbattista A, Miceli R, Valagussa P, Bonadonna G. Time distribution of the recurrence risk for breast cancer patients undergoing mastectomy: further support about the concept of tumor dormancy. Breast Cancer Res Treat 1996; 41: 177-185.
-
(1996)
Breast Cancer Res Treat
, vol.41
, pp. 177-185
-
-
Demicheli, R.1
Abbattista, A.2
Miceli, R.3
Valagussa, P.4
Bonadonna, G.5
-
27
-
-
1542319129
-
Cancer without disease
-
Folkman J, Kalluri R. Cancer without disease. Nature 2004; 427: 787.
-
(2004)
Nature
, vol.427
, pp. 787
-
-
Folkman, J.1
Kalluri, R.2
-
28
-
-
0028951043
-
Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression
-
Holmgren L, O'Reilly M, Folkman J. Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nat Med 1995; 1: 149-153.
-
(1995)
Nat Med
, vol.1
, pp. 149-153
-
-
Holmgren, L.1
O'Reilly, M.2
Folkman, J.3
-
29
-
-
0036532065
-
Persistence of solitary mammary carcinoma cells in a secondary site: A possible contributor to dormancy
-
Naumov GN, MacDonald IC, Weinmeister PM, Kerkvliet N, Nadkarni KV, Wilson SM, et al. Persistence of solitary mammary carcinoma cells in a secondary site: a possible contributor to dormancy. Cancer Res 2002; 62: 2162-2168.
-
(2002)
Cancer Res
, vol.62
, pp. 2162-2168
-
-
Naumov, G.N.1
MacDonald, I.C.2
Weinmeister, P.M.3
Kerkvliet, N.4
Nadkarni, K.V.5
Wilson, S.M.6
-
30
-
-
0141679385
-
Prolonged dormancy and site-specific growth potential of cancer cells spontaneously disseminated from nonmetastatic breast tumors as revealed by labeling with green fluorescent protein
-
Goodison S, Kawai K, Hihara J, Jiang P, Yang M, Urquidi V, et al. Prolonged dormancy and site-specific growth potential of cancer cells spontaneously disseminated from nonmetastatic breast tumors as revealed by labeling with green fluorescent protein. Clin Cancer Res 2003; 9:3808-3814.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3808-3814
-
-
Goodison, S.1
Kawai, K.2
Hihara, J.3
Jiang, P.4
Yang, M.5
Urquidi, V.6
-
31
-
-
2942538264
-
Dissecting the metastatic cascade
-
Pantel K, Brakenhoff RH. Dissecting the metastatic cascade. Nat Rev Cancer 2004; 4: 448-456.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 448-456
-
-
Pantel, K.1
Brakenhoff, R.H.2
-
32
-
-
0036720684
-
Persistence of microscopic human cancers in mice: Alterations in the angiogenic balance accompanies loss of tumor dormancy
-
Udagawa T, Fernandez A, Achilles EQ Folkman J, D'Amato RJ. Persistence of microscopic human cancers in mice: alterations in the angiogenic balance accompanies loss of tumor dormancy. FASEB J 2002; 16: 1361-1370.
-
(2002)
FASEB J
, vol.16
, pp. 1361-1370
-
-
Udagawa, T.1
Fernandez, A.2
Achilles, E.Q.3
Folkman, J.4
D'Amato, R.J.5
-
33
-
-
33645226260
-
Interruption of tumor dormancy by a transient angiogenic burst within the tumor microenvironment
-
Indraccolo S, Stievano L, Minuzzo S, Tosello, V, Esposito G, Piovan E, et al. Interruption of tumor dormancy by a transient angiogenic burst within the tumor microenvironment. Proc Natl Acad Sci U S A 2006; 103:4216-4221.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 4216-4221
-
-
Indraccolo, S.1
Stievano, L.2
Minuzzo, S.3
Tosello, V.4
Esposito, G.5
Piovan, E.6
-
36
-
-
16844368698
-
Tumour stem cells and drug resistance
-
Dean M, Fojo T, Bates S. Tumour stem cells and drug resistance. Nat Rev Cancer 2005; 5: 275-284.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 275-284
-
-
Dean, M.1
Fojo, T.2
Bates, S.3
-
37
-
-
21344454219
-
Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
-
Ponti D, Costa A, Zaffaroni N, Pratesi G, Petrangolini G, Coradini D, et al. Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res 2005; 65: 5506-5511.
-
(2005)
Cancer Res
, vol.65
, pp. 5506-5511
-
-
Ponti, D.1
Costa, A.2
Zaffaroni, N.3
Pratesi, G.4
Petrangolini, G.5
Coradini, D.6
-
38
-
-
33645772227
-
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain
-
San L, Hui AM, Su Q, Vortmeyer A, Kotliarov Y, Pastorino S, et al. Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain. Cancer Cell 2006; 9: 287-300.
-
(2006)
Cancer Cell
, vol.9
, pp. 287-300
-
-
San, L.1
Hui, A.M.2
Su, Q.3
Vortmeyer, A.4
Kotliarov, Y.5
Pastorino, S.6
-
39
-
-
0032945433
-
Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization
-
Takahashi T, Kalka C, Masuda H, Chen D, Silver M, Kearney M, et al. Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization. Nat Med 1999; 5: 434-438.
-
(1999)
Nat Med
, vol.5
, pp. 434-438
-
-
Takahashi, T.1
Kalka, C.2
Masuda, H.3
Chen, D.4
Silver, M.5
Kearney, M.6
-
40
-
-
27144446814
-
Circulating endothelial progenitor cells
-
Garmy-Susini B, Varner JA. Circulating endothelial progenitor cells. Br J Cancer 2005; 93: 855-858.
-
(2005)
Br J Cancer
, vol.93
, pp. 855-858
-
-
Garmy-Susini, B.1
Varner, J.A.2
-
41
-
-
0031019745
-
Isolation of putative progenitor endothelial cells for angiogenesis
-
Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, Li T, et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997; 275: 964-967.
-
(1997)
Science
, vol.275
, pp. 964-967
-
-
Asahara, T.1
Murohara, T.2
Sullivan, A.3
Silver, M.4
van der Zee, R.5
Li, T.6
-
42
-
-
2642571660
-
Vascular-targeting therapies for treatment of malignant disease
-
Siemann DW, Chaplin DJ, Horsman MR. Vascular-targeting therapies for treatment of malignant disease. Cancer 2004; 100: 2491-2499.
-
(2004)
Cancer
, vol.100
, pp. 2491-2499
-
-
Siemann, D.W.1
Chaplin, D.J.2
Horsman, M.R.3
-
44
-
-
19944432454
-
Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; Implications for cellular surrogate marker analysis of anti-angiogenesis
-
Shaked Y, Bertolini F, Man S, Rogers MS, Cervi D, Foutz T, et al. Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; Implications for cellular surrogate marker analysis of anti-angiogenesis. Cancer Cell 2005; 7: 101-111.
-
(2005)
Cancer Cell
, vol.7
, pp. 101-111
-
-
Shaked, Y.1
Bertolini, F.2
Man, S.3
Rogers, M.S.4
Cervi, D.5
Foutz, T.6
-
45
-
-
33749005405
-
Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors
-
Shaked Y, Ciarrocchi A, Franco M, Lee CR, Man S, Cheung AM, et al. Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors. Science 2006; 313:1785-1787.
-
(2006)
Science
, vol.313
, pp. 1785-1787
-
-
Shaked, Y.1
Ciarrocchi, A.2
Franco, M.3
Lee, C.R.4
Man, S.5
Cheung, A.M.6
-
46
-
-
20344394640
-
The vascular disrupting agent ZD6126 shows increased antitumor efficacy and enhanced radiation response in large, advanced tumors
-
Siemann DW, Rojiani AM. The vascular disrupting agent ZD6126 shows increased antitumor efficacy and enhanced radiation response in large, advanced tumors. Int J Radiat Oncol Biol Phys 2005; 62: 846-853.
-
(2005)
Int J Radiat Oncol Biol Phys
, vol.62
, pp. 846-853
-
-
Siemann, D.W.1
Rojiani, A.M.2
-
47
-
-
20144386931
-
Contribution of bone marrow-derived endothelial cells to human tumor vasculature
-
Peters BA, Diaz LA, Polyak K, Meszler L, Romans K, Guinan EC, et al. Contribution of bone marrow-derived endothelial cells to human tumor vasculature. Nat Med 2005; 11: 261-262.
-
(2005)
Nat Med
, vol.11
, pp. 261-262
-
-
Peters, B.A.1
Diaz, L.A.2
Polyak, K.3
Meszler, L.4
Romans, K.5
Guinan, E.C.6
-
48
-
-
35648956232
-
Combined anti-angiogenesis and antiepidermal growth factor receptor targeting in the treatment of cancer: Hold back, we are not there yet
-
Baselga J, Tabernero J. Combined anti-angiogenesis and antiepidermal growth factor receptor targeting in the treatment of cancer: hold back, we are not there yet. J Clin Oncol 2007; 25: 4516-4518.
-
(2007)
J Clin Oncol
, vol.25
, pp. 4516-4518
-
-
Baselga, J.1
Tabernero, J.2
|