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Volumn 7, Issue 7, 2008, Pages 2252-2260

Synergistic tumoricidal effect of combined hMUC1 vaccination and hNIS radioiodine gene therapy

Author keywords

[No Author keywords available]

Indexed keywords

CD11 ANTIGEN; DNA VACCINE; GAMMA INTERFERON; IODINE 131; PERTECHNETIC ACID TC 99M; PROLYLASPARTYLTHREONYLARGINYLPROLYLALANYLPROLYLGLYCYLSERYL THREONYLALANYLPROLYLPROLYLALANYLHISTIDYLGLYCYLVALYLTHREONYLSERYLALANYL PROLYLASPARTYLTHREONYLARGINYLPROLYLALANYLPROLYLGLYCYLSERYLTHREONINE; SODIUM IODIDE SYMPORTER; UNCLASSIFIED DRUG; CA 15-3 ANTIGEN; COTRANSPORTER; GLYCOPROTEIN P 15095; MUC1 PROTEIN, HUMAN; RADIOACTIVE IODINE;

EID: 51049087087     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-08-0277     Document Type: Article
Times cited : (11)

References (41)
  • 1
    • 0033010852 scopus 로고    scopus 로고
    • Molecular mechanisms of ionizing radiation-induced apoptosis
    • Watters D. Molecular mechanisms of ionizing radiation-induced apoptosis. Immunol Cell Biol 1999;77:263-71.
    • (1999) Immunol Cell Biol , vol.77 , pp. 263-271
    • Watters, D.1
  • 2
    • 0033572416 scopus 로고    scopus 로고
    • Flt3-ligand administration after radiation therapy prolongs survival in a murine model of metastatic lung cancer
    • Chakravarty PK, Alfieri A, Thomas EK, et al. Flt3-ligand administration after radiation therapy prolongs survival in a murine model of metastatic lung cancer. Cancer Res 1999;59:6028-32.
    • (1999) Cancer Res , vol.59 , pp. 6028-6032
    • Chakravarty, P.K.1    Alfieri, A.2    Thomas, E.K.3
  • 3
    • 20944441967 scopus 로고    scopus 로고
    • Combining a recombinant cancer vaccine with standard definitive radiotherapy in patients with localized prostate cancer
    • Gulley JL, Arlen PM, Bastian A, et al. Combining a recombinant cancer vaccine with standard definitive radiotherapy in patients with localized prostate cancer. Clin Cancer Res 2005;11:3353-62.
    • (2005) Clin Cancer Res , vol.11 , pp. 3353-3362
    • Gulley, J.L.1    Arlen, P.M.2    Bastian, A.3
  • 4
    • 0035892360 scopus 로고    scopus 로고
    • Combination of γ-irradiation and dendritic cell administration induces a potent antitumor response in tumor-bearing mice: Approach to treatment of advanced stage cancer
    • Nikitina EY, Gabrilovich DI. Combination of γ-irradiation and dendritic cell administration induces a potent antitumor response in tumor-bearing mice: approach to treatment of advanced stage cancer. Int J Cancer 2001;94:825-33.
    • (2001) Int J Cancer , vol.94 , pp. 825-833
    • Nikitina, E.Y.1    Gabrilovich, D.I.2
  • 5
    • 0028318967 scopus 로고
    • The effect of irradiation on expression of HLA class I antigens in human brain tumors in culture
    • Klein B, Loven D, Lurie H, et al. The effect of irradiation on expression of HLA class I antigens in human brain tumors in culture. J Neurosurg 1994;80:1074-7.
    • (1994) J Neurosurg , vol.80 , pp. 1074-1077
    • Klein, B.1    Loven, D.2    Lurie, H.3
  • 6
    • 0031588408 scopus 로고    scopus 로고
    • Up-regulation of Fas (CD95) in human p53wild-type cancer cells treated with ionizing radiation
    • Sheard MA, Vojtesek B, Janakova L, Kovarik J, Zaloudik J. Up-regulation of Fas (CD95) in human p53wild-type cancer cells treated with ionizing radiation. Int J Cancer 1997;73:757-62.
    • (1997) Int J Cancer , vol.73 , pp. 757-762
    • Sheard, M.A.1    Vojtesek, B.2    Janakova, L.3    Kovarik, J.4    Zaloudik, J.5
  • 7
    • 0037942745 scopus 로고    scopus 로고
    • Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy
    • Chakraborty M, Abrams SI, Camphausen K, et al. Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy. J Immunol 2003;170:6338-47.
    • (2003) J Immunol , vol.170 , pp. 6338-6347
    • Chakraborty, M.1    Abrams, S.I.2    Camphausen, K.3
  • 9
    • 0025029968 scopus 로고
    • Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin
    • Gendler SJ, Lancaster CA, Taylor-Papadimitriou J, et al. Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin. J Biol Chem 1990;265:15286-93.
    • (1990) J Biol Chem , vol.265 , pp. 15286-15293
    • Gendler, S.J.1    Lancaster, C.A.2    Taylor-Papadimitriou, J.3
  • 10
    • 0023741252 scopus 로고
    • A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats
    • Gendler S, Taylor-Papadimitriou J, Duhig T, Rothbard J, Burchell J. A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats. J Biol Chem 1988;263:12820-3.
    • (1988) J Biol Chem , vol.263 , pp. 12820-12823
    • Gendler, S.1    Taylor-Papadimitriou, J.2    Duhig, T.3    Rothbard, J.4    Burchell, J.5
  • 12
    • 33645095443 scopus 로고    scopus 로고
    • A MUC1/IL-18 DNA vaccine induces anti-tumor immunity and increased survival in MUC1 transgenic mice
    • Snyder LA, Goletz TJ, Gunn GR, et al. A MUC1/IL-18 DNA vaccine induces anti-tumor immunity and increased survival in MUC1 transgenic mice. Vaccine 2006;24:3340-52.
    • (2006) Vaccine , vol.24 , pp. 3340-3352
    • Snyder, L.A.1    Goletz, T.J.2    Gunn, G.R.3
  • 13
    • 18344392257 scopus 로고    scopus 로고
    • Novel vaccination protocol consisting of injecting MUC1 DNA and nonprimed dendritic cells at the same region greatly enhanced MUC1-specific antitumor immunity in a murine model
    • Kontani K, Taguchi O, Ozaki Y, et al. Novel vaccination protocol consisting of injecting MUC1 DNA and nonprimed dendritic cells at the same region greatly enhanced MUC1-specific antitumor immunity in a murine model. Cancer Gene Ther 2002;9:330-7.
    • (2002) Cancer Gene Ther , vol.9 , pp. 330-337
    • Kontani, K.1    Taguchi, O.2    Ozaki, Y.3
  • 14
    • 0036732003 scopus 로고    scopus 로고
    • Sodium iodide symporter: Its role in nuclear medicine
    • Chung JK. Sodium iodide symporter: its role in nuclear medicine. J Nucleic Med 2002;43:1188-200.
    • (2002) J Nucleic Med , vol.43 , pp. 1188-1200
    • Chung, J.K.1
  • 15
    • 0033922682 scopus 로고    scopus 로고
    • Molecular analysis of the sodium/iodide symporter: Impact on thyroid and extrathyroid pathophysiology
    • De La Vieja A, Dohan O, Levy O, Carrasco N. Molecular analysis of the sodium/iodide symporter: impact on thyroid and extrathyroid pathophysiology. Physiol Rev 2000;80:1083-105.
    • (2000) Physiol Rev , vol.80 , pp. 1083-1105
    • De La Vieja, A.1    Dohan, O.2    Levy, O.3    Carrasco, N.4
  • 16
    • 0033693586 scopus 로고    scopus 로고
    • Treatment of prostate cancer by radioiodine therapy after tissue-specific expression of the sodium iodide symporter
    • Spitzweg C, O'Connor MK, Bergert ER, Tindall DJ, Young CY, Morris JC. Treatment of prostate cancer by radioiodine therapy after tissue-specific expression of the sodium iodide symporter. Cancer Res 2000;60:6526-30.
    • (2000) Cancer Res , vol.60 , pp. 6526-6530
    • Spitzweg, C.1    O'Connor, M.K.2    Bergert, E.R.3    Tindall, D.J.4    Young, C.Y.5    Morris, J.C.6
  • 17
    • 0035171630 scopus 로고    scopus 로고
    • In vivo sodium iodide symporter gene therapy of prostate cancer
    • Spitzweg C, Dietz AB, O'Connor MK, et al. In vivo sodium iodide symporter gene therapy of prostate cancer. Gene Ther 2001;8:1524-31.
    • (2001) Gene Ther , vol.8 , pp. 1524-1531
    • Spitzweg, C.1    Dietz, A.B.2    O'Connor, M.K.3
  • 18
    • 33745544663 scopus 로고    scopus 로고
    • Radioiodine therapy of hepatoma using targeted transfer of the human sodium/iodide symporter gene
    • Chen L, Altmann A, Mier W, et al. Radioiodine therapy of hepatoma using targeted transfer of the human sodium/iodide symporter gene. J Nucleic Med 2006;47:854-62.
    • (2006) J Nucleic Med , vol.47 , pp. 854-862
    • Chen, L.1    Altmann, A.2    Mier, W.3
  • 19
    • 13544264755 scopus 로고    scopus 로고
    • Radioiodine therapy of colon cancer following tissue-specific sodium iodide symporter gene transfer
    • Scholz IV, Cengic N, Baker CH, et al. Radioiodine therapy of colon cancer following tissue-specific sodium iodide symporter gene transfer. Gene Ther 2005;12:272-80.
    • (2005) Gene Ther , vol.12 , pp. 272-280
    • Scholz, I.V.1    Cengic, N.2    Baker, C.H.3
  • 20
    • 34548290379 scopus 로고    scopus 로고
    • Human sodium iodide symporter gene adjunctive radiotherapy to enhance the preventive effect of hMUC1 DNA vaccine
    • Jeon YH, Choi Y, Kim HJ, et al. Human sodium iodide symporter gene adjunctive radiotherapy to enhance the preventive effect of hMUC1 DNA vaccine. Int J Cancer 2007;121:1593-9.
    • (2007) Int J Cancer , vol.121 , pp. 1593-1599
    • Jeon, Y.H.1    Choi, Y.2    Kim, H.J.3
  • 21
    • 0033083046 scopus 로고    scopus 로고
    • Radioisotope concentrator gene therapy using the sodium/iodide symporter gene
    • Mandell RB, Mandell LZ, Link CJ, Jr. Radioisotope concentrator gene therapy using the sodium/iodide symporter gene. Cancer Res 1999;59:661-8.
    • (1999) Cancer Res , vol.59 , pp. 661-668
    • Mandell, R.B.1    Mandell, L.Z.2    Link Jr., C.J.3
  • 22
    • 0030977234 scopus 로고    scopus 로고
    • Targeting of HIV-1 antigens for rapid intracellular degradation enhances cytotoxic T lymphocyte (CTL) recognition and the induction of de novo CTL responses in vivo after immunization
    • Tobery TW, Siliciano RF. Targeting of HIV-1 antigens for rapid intracellular degradation enhances cytotoxic T lymphocyte (CTL) recognition and the induction of de novo CTL responses in vivo after immunization. J Exp Med 1997;185:909-20.
    • (1997) J Exp Med , vol.185 , pp. 909-920
    • Tobery, T.W.1    Siliciano, R.F.2
  • 23
    • 0032568415 scopus 로고    scopus 로고
    • Enhanced responses to a DNA vaccine encoding a fusion antigen that is directed to sites of immune induction
    • Boyle JS, Brady JL, Lew AM. Enhanced responses to a DNA vaccine encoding a fusion antigen that is directed to sites of immune induction. Nature 1998;392:408-11.
    • (1998) Nature , vol.392 , pp. 408-411
    • Boyle, J.S.1    Brady, J.L.2    Lew, A.M.3
  • 24
    • 0031761363 scopus 로고    scopus 로고
    • DNA vaccines with single-chain Fv fused to fragment C of tetanus toxin induce protective immunity against lymphoma and myeloma
    • King CA, Spellerberg MB, Zhu D, et al. DNA vaccines with single-chain Fv fused to fragment C of tetanus toxin induce protective immunity against lymphoma and myeloma. Nat Med 1998;4:1281-6.
    • (1998) Nat Med , vol.4 , pp. 1281-1286
    • King, C.A.1    Spellerberg, M.B.2    Zhu, D.3
  • 25
    • 0022387966 scopus 로고
    • The serologic response of patients with stage II melanoma to allogeneic melanoma cell vaccines
    • Livingston PO, Kaelin K, Pinsky CM, Oettgen HF, Old LJ. The serologic response of patients with stage II melanoma to allogeneic melanoma cell vaccines. Cancer 1985;56:2194-200.
    • (1985) Cancer , vol.56 , pp. 2194-2200
    • Livingston, P.O.1    Kaelin, K.2    Pinsky, C.M.3    Oettgen, H.F.4    Old, L.J.5
  • 26
    • 0025147441 scopus 로고
    • Treatment of metastatic melanoma with an autologous tumor-cell vaccine: Clinical and immunologic results in 64 patients
    • Berd D, Maguire HC, Jr., McCue P, Mastrangelo MJ. Treatment of metastatic melanoma with an autologous tumor-cell vaccine: clinical and immunologic results in 64 patients. J Clin Oncol 1990;8:1858-67.
    • (1990) J Clin Oncol , vol.8 , pp. 1858-1867
    • Berd, D.1    Maguire Jr., H.C.2    McCue, P.3    Mastrangelo, M.J.4
  • 27
    • 0028793675 scopus 로고
    • Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity
    • Mayordomo JI, Zorina T, Storkus WJ, et al. Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity. Nat Med 1995;1:1297-302.
    • (1995) Nat Med , vol.1 , pp. 1297-1302
    • Mayordomo, J.I.1    Zorina, T.2    Storkus, W.J.3
  • 28
    • 0030028770 scopus 로고    scopus 로고
    • Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo
    • Paglia P, Chiodoni C, Rodolfo M, Colombo MP. Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo. J Exp Med 1996;183:317-22.
    • (1996) J Exp Med , vol.183 , pp. 317-322
    • Paglia, P.1    Chiodoni, C.2    Rodolfo, M.3    Colombo, M.P.4
  • 29
    • 17144454609 scopus 로고    scopus 로고
    • + T cells against influenza virus induced by vaccination with nucleoprotein DNA
    • + T cells against influenza virus induced by vaccination with nucleoprotein DNA. J Virol 1998;72:5648-53.
    • (1998) J Virol , vol.72 , pp. 5648-5653
    • Ulmer, J.B.1    Fu, T.M.2    Deck, R.R.3
  • 30
    • 0027411456 scopus 로고
    • Heterologous protection against influenza by injection of DNA encoding a viral protein
    • Ulmer JB, Donnelly JJ, Parker SE, et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 1993;259:1745-9.
    • (1993) Science , vol.259 , pp. 1745-1749
    • Ulmer, J.B.1    Donnelly, J.J.2    Parker, S.E.3
  • 31
    • 0034046182 scopus 로고    scopus 로고
    • DNA vaccines: Immunology, application, and optimization
    • Gurunathan S, Klinman DM, Seder RA. DNA vaccines: immunology, application, and optimization. Annu Rev Immunol 2000;18:927-74.
    • (2000) Annu Rev Immunol , vol.18 , pp. 927-974
    • Gurunathan, S.1    Klinman, D.M.2    Seder, R.A.3
  • 32
    • 0042964824 scopus 로고    scopus 로고
    • Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins
    • Kim TW, Hung CF, Ling M, et al. Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins. J Clin Invest 2003;112:109-17.
    • (2003) J Clin Invest , vol.112 , pp. 109-117
    • Kim, T.W.1    Hung, C.F.2    Ling, M.3
  • 33
    • 1242273662 scopus 로고    scopus 로고
    • Enhancement of suicidal DNA vaccine potency by delaying suicidal DNA-induced cell death
    • Kim TW, Hung CF, Juang J, He L, Hardwick JM, Wu TC. Enhancement of suicidal DNA vaccine potency by delaying suicidal DNA-induced cell death. Gene Ther 2004;11:336-42.
    • (2004) Gene Ther , vol.11 , pp. 336-342
    • Kim, T.W.1    Hung, C.F.2    Juang, J.3    He, L.4    Hardwick, J.M.5    Wu, T.C.6
  • 34
    • 0038697491 scopus 로고    scopus 로고
    • Inability to immunize patients with metastatic melanoma using plasmid DNA encoding the gp100 melanoma-melanocyte antigen
    • Rosenberg SA, Yang JC, Sherry RM, et al. Inability to immunize patients with metastatic melanoma using plasmid DNA encoding the gp100 melanoma-melanocyte antigen. Hum Gene Ther 2003;14:709-14.
    • (2003) Hum Gene Ther , vol.14 , pp. 709-714
    • Rosenberg, S.A.1    Yang, J.C.2    Sherry, R.M.3
  • 35
    • 0032538597 scopus 로고    scopus 로고
    • Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine
    • Wang R, Doolan DL, Le TP, et al. Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine. Science 1998;282:476-80.
    • (1998) Science , vol.282 , pp. 476-480
    • Wang, R.1    Doolan2    DL, L.T.3
  • 37
    • 0011998302 scopus 로고    scopus 로고
    • Radiopharmaceuticals in oncology
    • Khalkhali IMJ, Goldsmith SJ, editors, Philadelphia PA, Lippincott,Williams & Wilkins;
    • Vallabhajosula S. Radiopharmaceuticals in oncology. In: Khalkhali IMJ, Goldsmith SJ, editors. Nuclear oncology: diagnosis and therapy. Philadelphia (PA): Lippincott,Williams & Wilkins; 2001. p. 31-62.
    • (2001) Nuclear oncology: Diagnosis and therapy , pp. 31-62
    • Vallabhajosula, S.1
  • 38
    • 7444258053 scopus 로고    scopus 로고
    • Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes
    • Garnett CT, Palena C, Chakraborty M, Tsang KY, Schlom J, Hodge JW. Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes. Cancer Res 2004;64:7985-94.
    • (2004) Cancer Res , vol.64 , pp. 7985-7994
    • Garnett, C.T.1    Palena, C.2    Chakraborty, M.3    Tsang, K.Y.4    Schlom, J.5    Hodge, J.W.6
  • 39
    • 0034920535 scopus 로고    scopus 로고
    • Dendritic cells resurrect antigens from dead cells
    • Larsson M, Fonteneau JF, Bhardwaj N. Dendritic cells resurrect antigens from dead cells. Trends Immunol 2001;22:141-8.
    • (2001) Trends Immunol , vol.22 , pp. 141-148
    • Larsson, M.1    Fonteneau, J.F.2    Bhardwaj, N.3
  • 40
    • 6944247422 scopus 로고    scopus 로고
    • Establishment of a human hepatocellular carcinoma cell line highly expressing sodium iodide symporter for radionuclide gene therapy
    • Kang JH, Chung JK, Lee YJ, et al. Establishment of a human hepatocellular carcinoma cell line highly expressing sodium iodide symporter for radionuclide gene therapy. J Nucleic Med 2004;45:1571-6.
    • (2004) J Nucleic Med , vol.45 , pp. 1571-1576
    • Kang, J.H.1    Chung, J.K.2    Lee, Y.J.3
  • 41
    • 10044241857 scopus 로고    scopus 로고
    • In vitro and in vivo properties of a human anaplastic thyroid carcinoma cell line transfected with the sodium iodide symporter gene
    • Lee YJ, Chung JK, Shin JH, et al. In vitro and in vivo properties of a human anaplastic thyroid carcinoma cell line transfected with the sodium iodide symporter gene. Thyroid 2004;14:889-95.
    • (2004) Thyroid , vol.14 , pp. 889-895
    • Lee, Y.J.1    Chung, J.K.2    Shin, J.H.3


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