Clinical versatility of porcine hepatocytes in the light of interspecies differences in cytochrome P450 regulation and expression

Xenotransplantation

Volumn 15, Issue 4, 2008, Pages 208-217

  Kleine, Moritz ^a   Schrem, Harald ^a   Borlak, Jürgen ^b   Klempnauer, Jürgen ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

Author keywords

Bioartificial liver; IL 6; Liver failure; TNF ; Xenotransplantation

Indexed keywords

CYTOCHROME P450; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME REGULATION; FEMALE; HUMAN; HUMAN CELL; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPECIES DIFFERENCE;

AGED; ANIMALS; BASE SEQUENCE; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTOCHROME P-450 ENZYME SYSTEM; DNA PRIMERS; FEMALE; GENE EXPRESSION; HEPATOCYTES; HUMANS; INTERLEUKIN-6; LIVER FAILURE, ACUTE; LIVER, ARTIFICIAL; MALE; MIDDLE AGED; RNA, MESSENGER; SPECIES SPECIFICITY; SWINE; TRANSPLANTATION, HETEROLOGOUS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 50949126239     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/j.1399-3089.2008.00478.x     Document Type: Article

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