Bystander activation by cytokines of intrahepatic T cells in chronic viral hepatitis

Seminars in Liver Disease

Volumn 17, Issue 4, 1997, Pages 319-322

  Abrignani, Sergio ^a  

^a CHIRON VACCINES   (Italy)

Author keywords

Cytokines; Effector function; Immune response; T cells; Viral hepatitis

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; INTERLEUKIN 2; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

CHRONIC HEPATITIS; CYTOTOXIC T LYMPHOCYTE; HEPATITIS B; HEPATITIS C; HUMAN; MEMORY CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE ACTIVATION; VIRUS HEPATITIS;

EID: 0030692033     PISSN: 02728087     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-1007208     Document Type: Review

References (29)

1. Doherty PC, Hou S, Tripp RA. CD8+ T-cell memory to viruses. Curr Opin Immunol 6:545-552, 1994.
2. Nahill SR, Welsh RM. High frequency of cross-reactive cytotoxic T lymphocytes elicited during the virus-induced polyclonal cytotoxic T lymphocyte response. J Exp Med 177:317-327, 1993.
3. Carding SR, Allan W, McMickle A, et al. Activation of cytokine genes in T cells during primary and secondary murine influenza pneumonia. J Exp Med 177:475-482, 1993.
4. Meuer SC, Hussey RE, Fabbi M, et al. An alternative pathway of T-cell activation: A functional role for the 50 kdT11 sheep erythrocyte receptor protein. Cell 36:897-903, 1984.
5. Verwilghen J, Vandenberghe P, Wallays G, et al. Simultaneous ligation of CD5 and CD28 on resting T lymphocytes induces T cell activation in the absence of T cell receptor/CD3 occupancy. J Immunol 150:835-846, 1993.
6. Gilat D, Cahalon L, Hershkoviz R, et al Interplay of T cells and cytokines in the context of enzymatically modified extracellular matrix. Immunol Today 17:16-20, 1996.
7. Kuhin M, Kamoun M, Trinchieri G. Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells J Exp Med 180:211-222, 1994.
8. Bacon JCB, Premack BA, Gardner P, et al. Activation of dual T cell pathways by the chemokine RANTES. Science 269:1727-1730, 1995.
9. Unutmaz D, Pileri P, Abrignani S. Antigen-independent activation of naive and memory resting T cells by a cytokine combination. J Exp Med 180:1159-1164, 1994.
10. Unutmaz D, Baldoni F, Abrignani S Human naive T cells activated by cytokines differentiate between naive and memory T cells. Int Immunol 7:1417-1424, 1995.
11. Tough DF, Sprent J. Turnover of naive- and memory-phenotype T cells J Exp Med 179:1127-1135, 1994.
12. Sprent J. Lifespans of naive, memory and effector lymphocytes. Curr Opin Immunol 5:433-438, 1993.
13. Miller JFAP. Immunological function of the thymus Lancet 2:748-750, 1961.
14. Sprent J, Tough DF. Lymphocyte life-span and memory. Science 265:1395-1400, 1994.
15. Akbar AN, Terry L, Timms A, et al. Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells. J Immunol 140:2171-2178, 1988.
16. Ehlers S, Smith KA. Differentiation of T cell lymphokine gene expression: The in vitro acquisition of T cell memory. J Exp Med 173:25-36, 1991.
17. Beverley P. Immunological memory in T cells. Curr Opin Immunol 3:355-360, 1991.
18. Michie CA, McLean A, Alcock C, et al. Lifespan of human lymphocyte subsets defined by CD45 isoforms. Nature 360: 264-265, 1992.
19. Actor JK, Shirai M, Kullberg MC, et al. Helminth infection results in decreased virus-specific CD8+ cytotoxic T-cell and Th1 cytokine responses as well as delayed virus clearance. Proc Natl Acad Sci USA 90:948-952, 1993.
20. Beverley PCL. Is T-cell memory maintained by crossreactive stimulation? Immunol Today 11:203-205, 1990.
21. Gray K. Immunological memory: A function of antigen persistence Trends Microbiol 1:39-41, 1993.
22. Lau LL, Jamieson BD, Somasundaram T, et al. Cytotoxic T-cell memory with antigen. Nature 369:648-652, 1994.
23. Hou S, Hyland L, Ryan KW, et al. Virus-specific CD8+ T-cell memory determined by clonal burst size. Nature 369:652-654,1994.
24. EhI S, Homback J, Aichele P, et al. Bystander activation of cytotoxic T cells: Studies on the mechanism and evaluation of in vivo significance in a transgenic mouse model. J Exp Med 185: 1241-1251, 1997.
25. Ahmed R. Tickling memory T cells. Science 272:1904, 1996
26. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell 76:301-314, 1994.
27. Ando K, Moriyama T, Guidotti L, et al. Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis. J Exp Med 178:1541-1554, 1993.
28. Ballardini G, Groff P, Pontisso P, et al. Hepatitis C virus (HCV) genotype, tissue HCV antigens, hepatocellular expression of HLA-A,B,C, and intracellular adhesion-1 molecules. Clues to pathogenesis of hepatocellular damage and response to interferon treatment in patients with chronic hepatitis C. J Clin Invest 95:2067-2075, 1995.
29. Minutello MA, Pileri P, Unutmaz E, et al. Compartmentalization of T lymphocytes to the site of disease: Intrahepatic CD4+ T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C. J Exp Med 178:17-25, 1993.