Characterization and differentiation of iron status in anemic very low birth weight infants using a diagnostic nomogram

Neonatology

Volumn 95, Issue 2, 2009, Pages 164-171

  Kasper, David C ^a   Widness, John A ^b   Haiden, Nadja ^a   Berger, Angelika ^a   Hayde, Michael ^a   Pollak, Arnold ^a   Herkner, Kurt R ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

CHr; Diagnostic plot; Erythropoiesis; Ferritin index; Iron deficiency; sTfR; VLBW infants

Indexed keywords

FERRITIN; IRON;

ANEMIA; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; ERYTHROPOIESIS; GESTATIONAL AGE; HUMAN; INFANT; NOMOGRAM; PRIORITY JOURNAL; SEROLOGY; VALIDATION PROCESS; VERY LOW BIRTH WEIGHT;

ADMINISTRATION, ORAL; ANEMIA, IRON-DEFICIENCY; BODY WEIGHT; DRUG THERAPY, COMBINATION; ERYTHROPOIETIN, RECOMBINANT; FERRIC COMPOUNDS; FERRITINS; HEMOGLOBINS; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE, DISEASES; INFANT, VERY LOW BIRTH WEIGHT; INJECTIONS, INTRAVENOUS; IRON; NOMOGRAMS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RETICULOCYTES;

EID: 50949097127     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000153101     Document Type: Article

References (30)

1. Bell EF, Strauss RG, Widness JA, Mahoney LT, Mock DM, Seward VJ, Cress GA, Johnson KJ, Kromer IJ, Zimmerman MB: Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants. Pediatrics 2005;115:1685-1691.
2. Bohler T, Leo A, Stadler A, Linderkamp O: Mechanical fragility of erythrocyte membrane in neonates and adults. Pediatr Res 1992;32:92-96.
3. Pollak A, Hayde M, Hayn M, Herkner K, Lombard KA, Lubec G, Weninger M, Widness JA: Effect of intravenous iron supplementation on erythropoiesis in erythropoietin-treated premature infants. Pediatrics 2001;107:78-85.
4. Widness JA: Pathophysiology, diagnosis, and prevention of neonatal anemia. Neoreviews 2000;1:e61-e68.
5. Maier RF, Obladen M, Muller-Hansen I, Kattner E, Merz U, Arlettaz R, Groneck P, Hammer H, Kossel H, Verellen G, Stock GJ, Lacaze-Masmonteil T, Claris O, Wagner M, Matis J, Gilberg F: Early treatment with erythropoietin β ameliorates anemia and reduces transfusion requirements in infants with birth weights below 1,000 g. J Pediatr 2002;141:8-15.
6. Carbonell-Estrany X, Figueras-Aloy J, Alvarez E: Erythropoietin and prematurity - where do we stand? J Perinat Med 2005;33:277-286.
7. Aher S, Ohlsson A: Late erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants. Cochrane Database Syst Rev 2006;3:CD004868.
8. Aher SM, Ohlsson A: Early versus late erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants. Cochrane Database Syst Rev 2006;3:CD004865.
9. Dimitriou H, Stiakaki E, Markaki EA, Bolonaki I, Giannakopoulou C, Kalmanti M: Soluble transferrin receptor levels and soluble transferrin receptor/log ferritin index in the evaluation of erythropoietic status in childhood infections and malignancy. Acta Paediatr 2000;89:1169-1173.
10. Beguin Y: Soluble transferrin receptor for the evaluation of erythropoiesis and iron status. Clin Chim Acta 2003;329:9-22.
11. Thomas C, Kirschbaum A, Boehm D, Thomas L: The diagnostic plot: a concept for identifying different states of iron deficiency and monitoring the response to epoetin therapy. Med Oncol 2006;23:23-36.
12. Thomas C, Thomas L: Anemia of chronic disease: pathophysiology and laboratory diagnosis. Lab Hematol 2005;11:14-23.
13. Brugnara C, Schiller B, Moran J: Reticulocyte hemoglobin equivalent (Ret He) and assessment of iron-deficient states. Clin Lab Haematol 2006;28:303-308.
14. Ullrich C, Wu A, Armsby C, Rieber S, Wingerter S, Brugnara C, Shapiro D, Bernstein H: Screening healthy infants for iron deficiency using reticulocyte hemoglobin content. JAMA 2005;294:924-930.
15. Thomas C, Thomas L: Biochemical markers and hematologic indices in the diagnosis of functional iron deficiency. Clin Chem 2002;48:1066-1076.
16. Brugnara C: Reticulocyte cellular indices: a new approach in the diagnosis of anemias and monitoring of erythropoietic function. Crit Rev Clin Lab Sci 2000;37:93-130.
17. Brugnara C: Iron deficiency and erythropoiesis: new diagnostic approaches. Clin Chem 2003;49:1573-1578.
18. Brugnara C: Erythrocyte membrane transport physiology. Curr Opin Hematol 1997;4:122-127.
19. Choi JW: Sensitivity, specificity, and predictive value of serum soluble transferrin receptor at different stages of iron deficiency. Ann Clin Lab Sci 2005;35:435-439.
20. Mast AE, Blinder MA, Gronowski AM, Chumley C, Scott MG: Clinical utility of the soluble transferrin receptor and comparison with serum ferritin in several populations. Clin Chem 1998;44:45-51.
21. Labbe RF, Vreman HJ, Stevenson DK: Zinc protoporphyrin: a metabolite with a mission. Clin Chem 1999;45:2060-2072.
22. Lin XM, Ji CY, Liu WJ, Long Z, Shen XY: Levels of serum transferrin receptor and its response to Fe-supplement in Fe-deficient children. Br J Nutr 2006;96:1134-1139.
23. Vazquez Lopez MA, Carracedo A, Lendinez F, Munoz FJ, Lopez J, Munoz A: The usefulness of serum transferrin receptor for discriminating iron deficiency without anemia in children. Haematologica 2006;91:264-265.
24. Rettmer RL, Carlson TH, Origenes ML, Jack RM, Labb RF: Zinc protoporphyrin/heme ratio for diagnosis of preanemic iron deficiency. Pediatrics 1999;104:e37.
25. Ali MA, Luxton AW, Walker WH: Serum ferritin concentration and bone marrow iron stores: a prospective study. Can Med Assoc J 1978;118:945-946.
26. Lipschitz DA, Cook JD, Finch CA: A clinical evaluation of serum ferritin as an index of iron stores. N Engl J Med 1974;290:1213-1216.
27. Ridley FC, Harris J, Gottstein R, Emmerson AJ: Is supplementary iron useful when preterm infants are treated with erythropoietin? Arch Dis Child 2006;91:1036-1038.
28. Horl WH: Iron therapy for renal anemia: how much needed, how much harmful? Pediatr Nephrol 2007;22:480-489.
29. 12 on the transfusion requirements of extremely low birth weight infants. Pediatrics 2006;118:2004-2013.
30. 12 to reduce the severity of the anemia of prematurity. Am J Clin Nutr 1994;60:930-935.