Mitochondrial targeting adaptation of the hominoid-specific glutamate dehydrogenase driven by positive darwinian selection

PLoS Genetics

Volumn 4, Issue 8, 2008, Pages

  Rosso, Lia ^a   Marques, Ana C ^a,c   Reichert, Andreas S ^b   Kaessmann, Henrik ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b GOETHE UNIVERSITY   (Germany)

^c MRC Functional Genetics Unit   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMATE DEHYDROGENASE; GLUTAMIC ACID; LYSINE; ARABIDOPSIS PROTEIN; GLUD2 PROTEIN, HUMAN; GLUTAMATE DEHYDROGENASE (NADP); SIGNAL PEPTIDE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BRAIN; CYTOPLASM; GENE FUNCTION; HOMINID; HUMAN; HUMAN CELL; MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN LOCALIZATION; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CERCOPITHECUS; CHEMISTRY; ENZYMOLOGY; GENE DUPLICATION; GENETIC SELECTION; GENETICS; HAPLORHINI; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; MOUSE; PHYLOGENY; PHYSIOLOGY; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT; SPECIES DIFFERENCE;

HOMINOIDEA; HOMO; MAMMALIA;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ARABIDOPSIS PROTEINS; CELL LINE; CERCOPITHECUS AETHIOPS; EVOLUTION, MOLECULAR; GENE DUPLICATION; GLUTAMATE DEHYDROGENASE; GLUTAMATE DEHYDROGENASE (NADP+); HOMINIDAE; HUMANS; HYLOBATES; MICE; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN SORTING SIGNALS; PROTEIN TRANSPORT; SELECTION (GENETICS); SEQUENCE ALIGNMENT; SPECIES SPECIFICITY;

EID: 50849144657     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000150     Document Type: Article

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