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Volumn 83, Issue 11-12, 2008, Pages 438-446

Airway smooth muscle relaxation induced by 5-HT2A receptors: Role of Na+/K+-ATPase pump and Ca2+-activated K+ channels

Author keywords

5 HT2A receptors; Airway smooth muscle; BKCa channels; Na+ K+ ATPase pump; Relaxation

Indexed keywords

1 (1 METHYL 5 INDOLYL) 3 (3 METHYL 5 ISOTHIAZOLYL)UREA; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CALCIUM ACTIVATED POTASSIUM CHANNEL; CHARYBDOTOXIN; HISTAMINE; IBERIOTOXIN; KETANSERIN; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; N TERT BUTYL 3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 2 PHENYLPROPIONAMIDE; N(G) NITROARGININE METHYL ESTER; OUABAIN; PROPRANOLOL; SEROTONIN 1A ANTAGONIST; SEROTONIN 1B ANTAGONIST; SEROTONIN 1D ANTAGONIST; SEROTONIN 2 ANTAGONIST; SEROTONIN 2 RECEPTOR; TROPISETRON; UNCLASSIFIED DRUG;

EID: 50849132506     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2008.07.006     Document Type: Article
Times cited : (11)

References (45)
  • 2
    • 0027362895 scopus 로고
    • Common phosphatidylinositol 4,5-bisphosphate pools are involved in carbachol and serotonin activation of tracheal smooth muscle
    • Baron C.B., Pompeo J., Blackman D., and Coburn R.F. Common phosphatidylinositol 4,5-bisphosphate pools are involved in carbachol and serotonin activation of tracheal smooth muscle. Journal of Pharmacological and Experimental Therapeutics 266 1 (1993) 8-15
    • (1993) Journal of Pharmacological and Experimental Therapeutics , vol.266 , Issue.1 , pp. 8-15
    • Baron, C.B.1    Pompeo, J.2    Blackman, D.3    Coburn, R.F.4
  • 3
    • 0020000206 scopus 로고
    • Properties of single calcium-activated potassium channels in cultured rat muscle
    • Barrett J.N., Magleby K.L., and Pallotta B.S. Properties of single calcium-activated potassium channels in cultured rat muscle. Journal of Physiology 331 1 (1982) 211-230
    • (1982) Journal of Physiology , vol.331 , Issue.1 , pp. 211-230
    • Barrett, J.N.1    Magleby, K.L.2    Pallotta, B.S.3
  • 7
    • 0026050395 scopus 로고
    • Kinetic characterization of 5-hydroxytryptamine receptor desensitization in isolated guinea-pig trachea and rabbit aorta
    • Ben-Harari R.R., Dalton B.A., Osman R., and Maayani S. Kinetic characterization of 5-hydroxytryptamine receptor desensitization in isolated guinea-pig trachea and rabbit aorta. Journal of Pharmacology and Experimental Therapeutics 257 1 (1991) 416-424
    • (1991) Journal of Pharmacology and Experimental Therapeutics , vol.257 , Issue.1 , pp. 416-424
    • Ben-Harari, R.R.1    Dalton, B.A.2    Osman, R.3    Maayani, S.4
  • 8
    • 0025947163 scopus 로고
    • A pharmacologic examination of receptors mediating serotonin-induced bronchoconstriction in the anesthetized guinea pig
    • Buckner C.K., Dea D., Liberati N., and Krell R.D. A pharmacologic examination of receptors mediating serotonin-induced bronchoconstriction in the anesthetized guinea pig. Journal of Pharmacology and Experimental Therapeutics 257 1 (1991) 26-34
    • (1991) Journal of Pharmacology and Experimental Therapeutics , vol.257 , Issue.1 , pp. 26-34
    • Buckner, C.K.1    Dea, D.2    Liberati, N.3    Krell, R.D.4
  • 10
    • 0033964166 scopus 로고    scopus 로고
    • 5-HT modifiers as a potential treatment of asthma
    • Cazzola M., and Matera M.G. 5-HT modifiers as a potential treatment of asthma. Trends in Pharmacological Sciences 21 1 (2000) 13-16
    • (2000) Trends in Pharmacological Sciences , vol.21 , Issue.1 , pp. 13-16
    • Cazzola, M.1    Matera, M.G.2
  • 13
    • 0025317428 scopus 로고
    • Responses of equine trachealis and lung parenchyma to methacholine, histamine, serotonin, prostanoids, and leukotrienes in vitro
    • Doucet M.Y., Jones T.R., and Ford-Hutchinson A.W. Responses of equine trachealis and lung parenchyma to methacholine, histamine, serotonin, prostanoids, and leukotrienes in vitro. Canadian Journal of Physiology and Pharmacology 68 3 (1990) 379-383
    • (1990) Canadian Journal of Physiology and Pharmacology , vol.68 , Issue.3 , pp. 379-383
    • Doucet, M.Y.1    Jones, T.R.2    Ford-Hutchinson, A.W.3
  • 16
    • 0036521963 scopus 로고    scopus 로고
    • Hypoxia-induced secretion of serotonin from intact pulmonary neuroepithelial bodies in neonatal rabbit
    • Fu X.W., Nurse C.A., Wong V., and Cutz E. Hypoxia-induced secretion of serotonin from intact pulmonary neuroepithelial bodies in neonatal rabbit. Journal of Physiology 539 Pt2 (2002) 503-510
    • (2002) Journal of Physiology , vol.539 , Issue.PART 2 , pp. 503-510
    • Fu, X.W.1    Nurse, C.A.2    Wong, V.3    Cutz, E.4
  • 17
    • 0030774639 scopus 로고    scopus 로고
    • Functional characteristics of heterologously expressed 5-HT receptors
    • Gerhardt C.C., and van Heerikhuizen H. Functional characteristics of heterologously expressed 5-HT receptors. European Journal of Pharmacology 334 1 (1997) 1-23
    • (1997) European Journal of Pharmacology , vol.334 , Issue.1 , pp. 1-23
    • Gerhardt, C.C.1    van Heerikhuizen, H.2
  • 19
    • 0019970131 scopus 로고
    • Pharmacological responses of human and porcine lung parenchyma, bronchus and pulmonary artery
    • Goldie R.G., Paterson J.W., and Wale J.L. Pharmacological responses of human and porcine lung parenchyma, bronchus and pulmonary artery. British Journal of Pharmacology 76 4 (1982) 515-521
    • (1982) British Journal of Pharmacology , vol.76 , Issue.4 , pp. 515-521
    • Goldie, R.G.1    Paterson, J.W.2    Wale, J.L.3
  • 21
    • 0036119338 scopus 로고    scopus 로고
    • Molecular, pharmacological and functional diversity of 5-HT receptors
    • Hoyer D., Hannon J.P., and Martin G.R. Molecular, pharmacological and functional diversity of 5-HT receptors. Pharmacology Biochemistry Behavior 71 4 (2002) 533-554
    • (2002) Pharmacology Biochemistry Behavior , vol.71 , Issue.4 , pp. 533-554
    • Hoyer, D.1    Hannon, J.P.2    Martin, G.R.3
  • 22
    • 0028950946 scopus 로고
    • Role of nitric oxide in non-adrenergic, non-cholinergic relaxation and modulation of excitatory neuroeffector transmission in the cat airway
    • Jing L., Inoue R., Tashiro K., Takahashi S., and Ito Y. Role of nitric oxide in non-adrenergic, non-cholinergic relaxation and modulation of excitatory neuroeffector transmission in the cat airway. Journal of Physiology 483 Pt1 (1995) 225-237
    • (1995) Journal of Physiology , vol.483 , Issue.PART 1 , pp. 225-237
    • Jing, L.1    Inoue, R.2    Tashiro, K.3    Takahashi, S.4    Ito, Y.5
  • 23
    • 0030669360 scopus 로고    scopus 로고
    • Role of 5-hydroxytryptamine and mast cells in the tachykinin-induced contraction of rat trachea in vitro
    • Joos G.F., Lefebvre R.A., Bullock G.R., and Pauwels R.A. Role of 5-hydroxytryptamine and mast cells in the tachykinin-induced contraction of rat trachea in vitro. European Journal of Pharmacology 338 3 (1997) 259-268
    • (1997) European Journal of Pharmacology , vol.338 , Issue.3 , pp. 259-268
    • Joos, G.F.1    Lefebvre, R.A.2    Bullock, G.R.3    Pauwels, R.A.4
  • 24
    • 0027241555 scopus 로고
    • Calcium mobilization by muscarinic cholinergic stimulation in bovine single airway smooth muscle
    • Kajita J., and Yamaguchi H. Calcium mobilization by muscarinic cholinergic stimulation in bovine single airway smooth muscle. American Journal of Physiology Lung Cell Molecular Physiology 264 5 Pt1 (1993) 496-503
    • (1993) American Journal of Physiology Lung Cell Molecular Physiology , vol.264 , Issue.5 PART 1 , pp. 496-503
    • Kajita, J.1    Yamaguchi, H.2
  • 25
    • 33645240964 scopus 로고    scopus 로고
    • Pharmacological characterization of 5-hydroxytryptamine-induced contraction in the chicken gastrointestinal tract
    • Kitazawa T., Ukai H., Komori S., and Taneike T. Pharmacological characterization of 5-hydroxytryptamine-induced contraction in the chicken gastrointestinal tract. Autonomic and Autacoid Pharmacology 26 2 (2006) 157-168
    • (2006) Autonomic and Autacoid Pharmacology , vol.26 , Issue.2 , pp. 157-168
    • Kitazawa, T.1    Ukai, H.2    Komori, S.3    Taneike, T.4
  • 26
    • 0016054457 scopus 로고
    • Neuroepithelial bodies in mammalian respiratory mucosa: light optical, histochemical and ultrastructural studies
    • (Suppl)
    • Lauweryns J.M., Cokelaere M., Theunynck P., and Deleersnyder M. Neuroepithelial bodies in mammalian respiratory mucosa: light optical, histochemical and ultrastructural studies. Chest 65 (1974) 22S-29S (Suppl)
    • (1974) Chest , vol.65
    • Lauweryns, J.M.1    Cokelaere, M.2    Theunynck, P.3    Deleersnyder, M.4
  • 27
    • 0031757638 scopus 로고    scopus 로고
    • The serotonin uptake-enhancing drug tianeptine suppresses asthmatic symptoms in children: a double-blind, crossover, placebo-controlled study
    • Lechin F., van der Dijs B., Orozco B., Jara H., Rada I., Lechin M.E., and Lechin A.E. The serotonin uptake-enhancing drug tianeptine suppresses asthmatic symptoms in children: a double-blind, crossover, placebo-controlled study. Journal of Clinical Pharmacology 38 10 (1998) 918-925
    • (1998) Journal of Clinical Pharmacology , vol.38 , Issue.10 , pp. 918-925
    • Lechin, F.1    van der Dijs, B.2    Orozco, B.3    Jara, H.4    Rada, I.5    Lechin, M.E.6    Lechin, A.E.7
  • 30
    • 34247209050 scopus 로고    scopus 로고
    • Bradykinin activates calcium-dependent potassium channels in cultured human airway smooth muscle cells
    • Liu B., Freyer A.M., and Hall I.P. Bradykinin activates calcium-dependent potassium channels in cultured human airway smooth muscle cells. American Journal of Physiology Lung Cell Molecular Physiology 292 4 (2007) 898-907
    • (2007) American Journal of Physiology Lung Cell Molecular Physiology , vol.292 , Issue.4 , pp. 898-907
    • Liu, B.1    Freyer, A.M.2    Hall, I.P.3
  • 33
    • 0021999732 scopus 로고
    • Mechanism by which serotonin attenuates contractile response of canine mesenteric arterial smooth muscle
    • Moreland R.S., van Breemen C., and Bohr D.F. Mechanism by which serotonin attenuates contractile response of canine mesenteric arterial smooth muscle. Journal of Pharmacoly and Experimental Therapeutics 232 2 (1985) 322-329
    • (1985) Journal of Pharmacoly and Experimental Therapeutics , vol.232 , Issue.2 , pp. 322-329
    • Moreland, R.S.1    van Breemen, C.2    Bohr, D.F.3
  • 34
    • 0027988484 scopus 로고
    • + channel openers and suppression of airway hyperreactivity
    • + channel openers and suppression of airway hyperreactivity. Trends in Pharmacological Sciences 15 12 (1994) 463-468
    • (1994) Trends in Pharmacological Sciences , vol.15 , Issue.12 , pp. 463-468
    • Morley, J.1
  • 35
    • 0029847520 scopus 로고    scopus 로고
    • Potassium channel modulation: a new drug principle for regulation of smooth muscle contractility. Studies on isolated airways and arteries
    • Nielsen-Kudsk J.E. Potassium channel modulation: a new drug principle for regulation of smooth muscle contractility. Studies on isolated airways and arteries. Danish Medical Bulletin 43 5 (1996) 429-447
    • (1996) Danish Medical Bulletin , vol.43 , Issue.5 , pp. 429-447
    • Nielsen-Kudsk, J.E.1
  • 41
    • 0029126312 scopus 로고
    • Potassium currents in human freshly isolated bronchial smooth muscle cells
    • Snetkov V.A., Hirst S.J., Twort C.H., and Ward J.P. Potassium currents in human freshly isolated bronchial smooth muscle cells. British Journal of Pharmacology 115 6 (1995) 1117-1125
    • (1995) British Journal of Pharmacology , vol.115 , Issue.6 , pp. 1117-1125
    • Snetkov, V.A.1    Hirst, S.J.2    Twort, C.H.3    Ward, J.P.4
  • 42
    • 0029762248 scopus 로고    scopus 로고
    • Ion channels in freshly isolated and cultured human bronchial smooth muscle cells
    • Snetkov V.A., Hirst S.J., and Ward J. Ion channels in freshly isolated and cultured human bronchial smooth muscle cells. Experimental Physiology 81 5 (1996) 791-804
    • (1996) Experimental Physiology , vol.81 , Issue.5 , pp. 791-804
    • Snetkov, V.A.1    Hirst, S.J.2    Ward, J.3
  • 44
    • 0024553348 scopus 로고
    • Sodium and calcium influx induced by phorbol esters in airway smooth muscle cells
    • Souhrada M., and Souhrada J.F. Sodium and calcium influx induced by phorbol esters in airway smooth muscle cells. American Review of Respiratory Disease 139 4 (1989) 927-932
    • (1989) American Review of Respiratory Disease , vol.139 , Issue.4 , pp. 927-932
    • Souhrada, M.1    Souhrada, J.F.2
  • 45
    • 10244256391 scopus 로고    scopus 로고
    • Effect of passive sensitization by serum from allergic asthmatic patients on the activity and expression of voltage-dependent delayed rectifier potassium channel in human bronchial smooth muscle cells
    • Zhao L.M., Xu Y.J., Zhang Z.X., Ni W., and Chen S.X. Effect of passive sensitization by serum from allergic asthmatic patients on the activity and expression of voltage-dependent delayed rectifier potassium channel in human bronchial smooth muscle cells. Chinese Medical Journal (Engl) 117 11 (2004) 1630-1636
    • (2004) Chinese Medical Journal (Engl) , vol.117 , Issue.11 , pp. 1630-1636
    • Zhao, L.M.1    Xu, Y.J.2    Zhang, Z.X.3    Ni, W.4    Chen, S.X.5


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