Analysis of the association of polymorphism in the osteoprotegerin gene with susceptibility to chronic kidney disease and periodontitis

Journal of Periodontal Research

Volumn 43, Issue 5, 2008, Pages 578-584

  Baioni, C S ^a   De Souza, C M ^a   Ribeiro Braosi, A P ^a   Luczyszyn, S M ^a   Dias Da Silva, M A ^b   Ignacio S A ^a   Naval MacHado, M A ^a   Benato Martins, W D ^a   Riella, M C ^a   Pecoits Filho, R ^a   Trevilatto, P C ^a  

^a PONTIFICAL CATHOLIC UNIVERSITY OF PARANÁ   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Chronic kidney disease; Genetic polymorphism; Osteoprotegerin; Periodontal disease

Indexed keywords

OSTEOPROTEGERIN;

ADULT; AGED; ARTICLE; BRAZIL; CHRONIC KIDNEY FAILURE; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; HUMAN; MALE; MIDDLE AGED; PERIODONTITIS; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; BRAZIL; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; OSTEOPROTEGERIN; PERIODONTITIS; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; YOUNG ADULT;

EID: 50849120053     PISSN: 00223484     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0765.2008.01098.x     Document Type: Article

References (71)

1. Goldfarb-Rumyantzev AS, Cheung AK, Habib AN et al. A population-based assessment of the familial component of chronic kidney disease mortality. Am J Nephrol 2006 26 : 142 148.
2. De Rossi SS, Glick M. Dental considerations for the patient with renal disease receiving hemodialysis. J Am Dent Assoc 1996 127 : 211 219.
3. Proctor R, Kumar N, Stein A, Moles D, Porter S. Oral and dental aspects of chronic renal failure. J Dent Res 2005 84 : 199 208.
4. Rose BD. Manual of Clinical Problems in Nephrology. Boston : Little Brown and Co., 1988 : 371 379.
5. Eigner TL, Jastak JT, Bennett WM. Achieving oral health in patients with renal failure and renal transplants. J Am Dent Assoc 1986 113 : 612 616.
6. Schoolwerth AC, Engelgau MM, Hostetter TH et al. Chronic kidney disease: a public health problem that needs a public health action plan. Prev Chronic Dis 2006 3 : A57.
7. Projecto SB Brasil. Condiçãoes da saúde bucal da população brasileira: resultados principais. Ministério da Saúde, Departamento de Atenção Básica, Brasilia : Ministério da Saúde, 2003 : 36 40.
8. Stenvinkel P, Lindholm B, Heimburger O. Novel approaches in an integrated therapy of inflammatory-associated wasting in end-stage renal disease. Semin Dial 2004 17 : 505 515.
9. Naugle K, Darby ML, Bauman DB, Lineberger LT, Powers R. The oral health status of individuals on renal dialysis. Ann Periodontol 1998 3 : 197 205.
10. Wyatt CM, Winston J. Renal disease in patients with HIV. Curr Infect Dis Rep 2006 8 : 76 81.
11. Rahmati MA, Craig RG, Homel P, Kaysen GA, Levin NW. Serum markers of periodontal disease status and inflammation in hemodialysis patients. Am J Kidney Dis 2002 40 : 983 989.
12. Garlet GP, Martins W Jr, Fonseca BA, Ferreira BR, Silva JS. Matrix metalloproteinases, their physiological inhibitors and osteoclast factors are differentially regulated by the cytokine profile in human periodontal disease. J Clin Periodontol 2004 31 : 671 679.
13. Ebisu S, Noiri Y. Oral Biofilms and bone resorption [in Japanese]. Clin Calcium 2007 17 : 179 184.
14. Kornman KS, Crane A, Wang HY et al. The interleukin-1 genotype as a severity factor in adult periodontal disease. J Clin Periodontol 1997 24 : 72 77.
15. Schenkein HA, Van Dyke TE. Early-onset periodontitis: systemic aspects of etiology and pathogenesis. Periodontol 2000 1994 6 : 7 25.
16. American Academy of Periodontology. Epidemiology of periodontal disease. J Periodontol 2005 76 : 1409 1419.
17. Marakoglu I, Gursoy UK, Demirer S, Sezer H. Periodontal status of chronic renal failure patients receiving hemodialysis. Yonsei Med J 2003 44 : 648 652.
18. Borawski J, Wilczynska-Borawska M, Stokowska W, Mysliwiec M. The periodontal status of pre-dialysis chronic kidney disease and maintenance dialysis patients. Nephrol Dial Transplant 2007 22 : 457 464.
19. Kshirsagar AV, Moss KL, Elter JR, Beck JD, Offenbacher S, Falk RJ. Periodontal disease is associated with renal insufficiency in the Atherosclerosis Risk in Communities (ARIC) study. Am J Kidney Dis 2005 45 : 650 657.
20. Khan S. Secondary hyperparathyroidism is associated with higher cost of care among chronic kidney disease patients with cardiovascular comorbidities. Nephron Clin Pract 2007 105 : c159 c164.
21. Floege J, Ketteler M. Vascular calcification in patients with end-stage renal disease. Nephrol Dial Transplant 2004 19 (suppl 5 V59 V66.
22. Jassal SK, von Muhlen D, Barrett-Connor E. Measures of renal function, BMD, bone loss, and osteoporotic fracture in older adults: the Rancho Bernardo study. J Bone Miner Res 2007 22 : 203 210.
23. Moe SM, Drueke T, Lameire N, Eknoyan G. Chronic kidney disease-mineral-bone disorder: a new paradigm. Adv Chronic Kidney Dis 2007 14 : 3 12.
24. Coen G, Ballanti P, Balducci A et al. Serum osteoprotegerin and renal osteodystrophy. Nephrol Dial Transplant 2002 17 : 233 238.
25. Montalban C, Garcia-Unzueta MT, De Francisco AL, Amado JA. Serum interleukin-6 in renal osteodystrophy: relationship with serum PTH and bone remodeling markers. Horm Metab Res 1999 31 : 14 17.
26. Simonet WS, Lacey DL, Dunstan CR et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 1997 89 : 309 319.
27. Yasuda H, Shima N, Nakagawa N et al. Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro. Endocrinology 1998 139 : 1329 1337.
28. Lacey DL, Timms E, Tan HL et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 1998 93 : 165 176.
29. Shalhoub V, Faust J, Boyle WJ et al. Osteoprotegerin and osteoprotegerin ligand effects on osteoclast formation from human peripheral blood mononuclear cell precursors. J Cell Biochem 1999 72 : 251 261.
30. Morinaga T, Nakagawa N, Yasuda H, Tsuda E, Higashio K. Cloning and characterization of the gene encoding human osteoprotegerin/osteoclastogenesis- inhibitory factor. Eur J Biochem 1998 254 : 685 691.
31. Trevilatto PC, Scarel-Caminaga RM, de Brito RB Jr, de Souza AP, Line SR. Polymorphism at position -174 of IL-6 gene is associated with susceptibility to chronic periodontitis in a Caucasian Brazilian population. J Clin Periodontol 2003 30 : 438 442.
32. Riemenschneider M, Konta L, Friedrich P et al. A functional polymorphism within plasminogen activator urokinase (PLAU) is associated with Alzheimer's disease. Hum Mol Genet 2006 15 : 2446 2456.
33. de Brito RB Jr, Scarel-Caminaga RM, Trevilatto PC, de Souza AP, Barros SP. Polymorphisms in the vitamin D receptor gene are associated with periodontal disease. J Periodontol 2004 75 : 1090 1095.
34. Machado de Souza C, Ribeiro Braosi AP, Luczyszyn SM et al. Association between vitamin D receptor gene polymorphisms and susceptibility to chronic kidney disease and periodontitis. Blood Purif 2007 25 : 411 419.
35. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of diet in Renal Disease Study Group. Ann Intern Med 1999 130 : 461 470.
36. Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999 4 : 1 6.
37. Loee H, Silness J. Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand 1963 21 : 533 551.
38. Silness J, Loee H. Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 1964 22 : 121 135.
39. Greene JC, Vermillion JR. The simplified oral hygiene index. J Am Dent Assoc 1964 68 : 7 13.
40. Trevilatto PC, Line SR. Use of buccal epithelial cells for PCR amplification of large DNA fragments. J Forensic Odontostomatol 2000 18 : 6 9.
41. Aidar M, Line SR. A simple and cost-effective protocol for DNA isolation from buccal epithelial cells. Braz Dent J 2007 18 : 148 152.
42. Brandstrom H, Stiger F, Lind L, Kahan T, Melhus H, Kindmark A. A single nucleotide polymorphism in the promoter region of the human gene for osteoprotegerin is related to vascular morphology and function. Biochem Biophys Res Commun 2002 293 : 13 17.
43. Soufi M, Schoppet M, Sattler AM et al. Osteoprotegerin gene polymorphisms in men with coronary artery disease. J Clin Endocrinol Metab 2004 89 : 3764 3768.
44. Yamashita T, Okada S, Higashio K, Nabeshima Y, Noda M. Double mutations in klotho and osteoprotegerin gene loci rescued osteopetrotic phenotype. Endocrinology 2002 143 : 4711 4717.
45. Boyle WJ, Simonet WS, Lacey DL. Osteoclast differentiation and activation. Nature 2003 6937 : 337 342.
46. Takai H, Kanematsu M, Yano K et al. Transforming growth factor-β stimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cells. J Biol Chem 1998 273 : 27091 27096.
47. Lee SK, Lorenzo JA. Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: correlation with osteoclast-like cell formation. Endocrinology 1999 140 : 3552 3561.
48. Kitazawa R, Kitazawa S, Maeda S. Promoter structure of mouse RANKL/TRANCE/OPGL/ODF gene. Biochim Biophys Acta 1999 1445 : 134 141.
49. Hofbauer LC, Gori F, Riggs BL et al. Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis. Endocrinology 1999 140 : 4382 4389.
50. Saika M, Inoue D, Kido S, Matsumoto T. 17β-Estradiol stimulates expression of osteoprotegerin by a mouse stromal cell line, ST-2, via estrogen receptor-α. Endocrinology 2001 142 : 2205 2212.
51. Nicholson GC, Moseley JM, Sexton PM, Mendelsohn FA, Martin TJ. Abundant calcitonin receptors in isolated rat osteoclasts. Biochemical and autoradiographic characterization. J Clin Invest 1986 78 : 355 360.
52. Hughes DE, Dai A, Tiffee JC, Li HH, Mundy GR, Boyce BF. Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-β. Nat Med 1996 2 : 1132 1136.
53. Crisafulli A, Romeo A, Floccari F et al. Osteoprotegerin and bone mineral density in hemodiafiltration patients. Ren Fail 2005 27 : 531 539.
54. Price PA, June HH, Buckley JR, Williamson MK. Osteoprotegerin inhibits artery calcification induced by warfarin and by vitamin D. Arterioscler Thromb Vasc Biol 2001 21 : 1610 1616.
55. Wada N, Maeda H, Yoshimine Y, Akamine A. Lipopolysaccharide stimulates expression of osteoprotegerin and receptor activator of NF-κB ligand in periodontal ligament fibroblasts through the induction of interleukin-1β and tumor necrosis factor-α. Bone 2004 35 : 629 635.
56. Mogi M, Otogoto J, Ota N, Togari A. Differential expression of RANKL and osteoprotegerin in gingival crevicular fluid of patients with periodontitis. J Dent Res 2004 83 : 166 169.
57. 2 is a main mediator in receptor activator of nuclear factor-κB ligand-dependent osteoclastogenesis induced by Porphyromonas gingivalis, Treponema denticola, and Treponema socranskii. J Periodontol 2005 76 : 813 820.
58. Miller CS, King CP Jr, Langub MC, Kryscio RJ, Thomas MV. Salivary biomarkers of existing periodontal disease: a cross-sectional study. J Am Dent Assoc 2006 137 : 322 329.
59. Kobayashi-Sakamoto M, Hirose K, Isogai E, Chiba I. NF-κB-dependent induction of osteoprotegerin by Porphyromonas gingivalis in endothelial cells. Biochem Biophys Res Commun 2004 315 : 107 112.
60. Crotti T, Smith MD, Hirsch R et al. Receptor activator NF κB ligand (RANKL) and osteoprotegerin (OPG) protein expression in periodontitis. J Periodont Res 2003 38 : 380 387.
61. Arko B, Prezelj J, Kocijancic A, Komel R, Marc J. Association of the osteoprotegerin gene polymorphisms with bone mineral density in postmenopausal women. Maturitas 2005 51 : 270 279.
62. Langdahl BL, Carstens M, Stenkjaer L, Eriksen EF. Polymorphisms in the osteoprotegerin gene are associated with osteoporotic fractures. J Bone Miner Res 2002 17 : 1245 1255.
63. Daroszewska A, Hocking LJ, McGuigan FE et al. Susceptibility to Paget's disease of bone is influenced by a common polymorphic variant of osteoprotegerin. J Bone Miner Res 2004 19 : 1506 1511.
64. Valdes AM, Hart DJ, Jones KA et al. Association study of candidate genes for the prevalence and progression of knee osteoarthritis. Arthritis Rheum 2004 50 : 2497 2507.
65. Vidal C, Brincat M, Xuereb Anastasi A. TNFRSF11B gene variants and bone mineral density in postmenopausal women in Malta. Maturitas 2006 53 : 386 395.
66. Soedarsono N, Rabello D, Kamei H et al. Evaluation of RANK/RANKL/OPG gene polymorphisms in aggressive periodontitis. J Periodont Res 2006 41 : 397 404.
67. Wohlfahrt JC, Wu T, Hodges JS, Hinrichs JE, Michalowicz BS. No association between selected candidate gene polymorphisms and severe chronic periodontitis. J Periodontol 2006 77 : 426 436.
68. Wagner J, Kaminski WE, Aslanidis C et al. Prevalence of OPG and IL-1 gene polymorphisms. J Clin Periodontol 2007 34 : 823 827.
69. Padiyar A, Sedor JR. Genetic and genomic approaches to glomerulosclerosis. Curr Mol Med 2005 5 : 497 507.
70. Michalowicz BS, Diehl SR, Gunsolley JC et al. Evidence of a substantial genetic basis for risk of adult periodontitis. J Periodontol 2000 71 : 1699 1707.
71. Rannala B. Finding genes influencing susceptibility to complex diseases in the post-genome era. Am J Pharmacogenomics 2001 1 : 203 221.